# Lycia Therapeutics, Inc. (LYCA)

> Source: Nexqual · https://nexqual.com/LYCA · data as of 2026-10-30 20:00 UTC · cite as "Nexqual, Lycia Therapeutics, Inc. (LYCA), nexqual.com/LYCA" · informational, not investment advice.

**Price:** USD 26.4 (-4.80% on the day) · last close of Oct 30, 2026; US market after hours, not a live price. Prev close 27.73 · day 25.66–27.59 · 52w 22.19–36.49 · market cap $1.38B · NMS

## Key facts
- Analysts: None.
- Total return with dividends: 1Y -12.0% vs S&P 500 +12.0%; 5Y -12.0% vs S&P 500 +72.5%.
- Dividend: LYCA paid no cash dividend in the last five years.

## Analysts
Consensus None.

## Total return (dividends reinvested)
|  | 1Y (from 2026-10-23) | 5Y (from 2026-10-19) |
|---|---|---|
| Total return | -12.0% | -12.0% |
| S&P 500 (SPY) | +12.0% | +72.5% |
| Per year | — | — |
| Volatility (annualized) | 119.5% | 15.1% |
| Max drawdown | -16.5% (Oct 2026→Oct 2026) | -12.0% (Oct 2026→Oct 2026) |

## Dividends
LYCA paid no cash dividend in the last five years.

## Peers (Biotechnology)
LGND (Ligand Pharmaceuticals Incorpor) USD 322.75 +1.71% · RYTM (Rhythm Pharmaceuticals, Inc.) USD 92.57 -0.54% · ORKA (Oruka Therapeutics, Inc.) USD 96.87 +0.23% · IONS (Ionis Pharmaceuticals, Inc.) USD 43.52 -1.96% · AXSM (Axsome Therapeutics, Inc.) USD 144.43 +0.68% · ABVX (Abivax SA) USD 86.59 -2.77%

## More
Full page: https://nexqual.com/LYCA · Free keyless MCP server with the same data and citations: https://mcp.nexqual.com/mcp · Guide for agents: https://nexqual.com/agents · https://nexqual.com/llms.txt

## Analyst estimates and revisions

| Period | EPS est. | 90d ago | Change | Revenue est. | Analysts |
|---|---|---|---|---|---|
| Current quarter | — | — | — | $0 | — |
| Next quarter | — | — | — | $0 | — |
| Current fiscal year | — | — | — | $0 | — |
| Next fiscal year | — | — | — | $0 | — |

## Recent SEC filings (last 120 days)
| Filed | Form | What it says | Filing |
|---|---|---|---|
| 2026-10-30 | Schedule 13G | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC: 11.9% of shares, passive 5%+ holder | https://www.sec.gov/Archives/edgar/data/1806540/000173804826000077/0001738048-26-000077-index.htm |
| 2026-10-26 | 8-K | Bylaws or fiscal-year change | https://www.sec.gov/Archives/edgar/data/1806540/000162828026067312/0001628280-26-067312-index.htm |
| 2026-10-20 | S-1/A | Registration of new shares | https://www.sec.gov/Archives/edgar/data/1806540/000162828026066381/0001628280-26-066381-index.htm |
| 2026-10-05 | S-1 | Registration of new shares | https://www.sec.gov/Archives/edgar/data/1806540/000162828026064973/0001628280-26-064973-index.htm |
Source: SEC EDGAR. Quotes are the opening words of each item as filed.