# Matinas BioPharma Holdings, Inc. (MTNB)

> Source: Nexqual · https://nexqual.com/MTNB · data as of 2026-10-15 20:00 UTC · cite as "Nexqual, Matinas BioPharma Holdings, Inc. (MTNB), nexqual.com/MTNB" · informational, not investment advice.

**Price:** USD 2.42 (-2.42% on the day) · last close of Oct 15, 2026; US market closed, not a live price. Prev close 2.48 · day 2.42–2.54 · 52w 2.27–27.9 · market cap $2.4M · ASE

## Key facts
- Total return with dividends: 1Y +41.5% vs S&P 500 +18.1%; 5Y -95.6% vs S&P 500 +85.1%.

## Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $33K | $3.2M | $1.1M | — | — | — |
| Operating income | -$24.7M | -$24.6M | -$23.8M | -$24.6M | -$7.0M | -$6.7M |
| Net income | -$23.3M | -$21.0M | -$22.9M | -$24.3M | -$10.3M | -$6.7M |
| EPS (diluted) | -$82.50 | -$75.00 | -$79.20 | -$74.70 | -$30.00 | — |
| Free cash flow | -$15.5M | -$20.0M | -$15.5M | — | — | — |
| Operating margin | -74954.5% | -771.3% | -2168.4% | — | — | — |
| Net margin | -70554.5% | -658.6% | -2093.2% | — | — | — |
| Revenue growth | -79.2% | +9560.6% | -65.6% | — | — | — |
| Cash + short-term investments | $49.6M | $28.8M | $13.8M | — | — | — |
Fiscal years end Dec. EPS is split-adjusted.

## Valuation (price ÷ last four quarters, through Jun 30, 2026)
P/B 1.3x · Earnings yield -282.27%

## Total return (dividends reinvested)
|  | 1Y (from 2025-10-16) | 5Y (from 2021-10-11) |
|---|---|---|
| Total return | +41.5% | -95.6% |
| S&P 500 (SPY) | +18.1% | +85.1% |
| Per year | +41.7% | -46.5% |
| Volatility (annualized) | 930.0% | 248.4% |
| Max drawdown | -96.4% (Jul 2026→Sep 2026) | -99.7% (Oct 2021→Sep 2026) |

## Peers (Biotechnology)
RYTM (Rhythm Pharmaceuticals, Inc.) USD 87.97 +1.57% · BLTE (Belite Bio, Inc) USD 152.62 +0.49% · IOVA (Iovance Biotherapeutics, Inc.) USD 14.72 +1.52% · PRAX (Praxis Precision Medicines, Inc) USD 248.24 +2.01% · IONS (Ionis Pharmaceuticals, Inc.) USD 44.12 +4.11% · SYRE (Spyre Therapeutics, Inc.) USD 80.1 -0.44%

## More
Full page: https://nexqual.com/MTNB · Free keyless MCP server with the same data and citations: https://mcp.nexqual.com/mcp · Guide for agents: https://nexqual.com/agents · https://nexqual.com/llms.txt