# OnKure Therapeutics, Inc. (OKUR)

> Source: Nexqual · https://nexqual.com/OKUR · data as of 2026-10-15 20:00 UTC · cite as "Nexqual, OnKure Therapeutics, Inc. (OKUR), nexqual.com/OKUR" · informational, not investment advice.

**Price:** USD 2.13 (-5.33% on the day) · last close of Oct 15, 2026; US market closed, not a live price. Prev close 2.25 · day 2.09–2.28 · 52w 2.09–5.38 · market cap $86.3M · NGM

## Key facts
- Analysts: Buy (mean 2.17 on a 1–5 scale) (6 analysts), mean target USD 15.5 (range 11–21).
- Total return with dividends: 1Y -26.0% vs S&P 500 +18.1%; 5Y -96.7% vs S&P 500 +85.1%.

## Analysts
Consensus Buy (mean 2.17 on a 1–5 scale), 6 analysts; mean target USD 15.5 (low 11, high 21).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-08-14 | Oppenheimer | Target lowered | Outperform | $30 → $14 |
| 2026-07-20 | HC Wainwright & Co. | Target lowered | Buy | $27 → $21 |

## Total return (dividends reinvested)
|  | 1Y (from 2025-10-16) | 5Y (from 2021-10-11) |
|---|---|---|
| Total return | -26.0% | -96.7% |
| S&P 500 (SPY) | +18.1% | +85.1% |
| Per year | -26.1% | -49.4% |
| Volatility (annualized) | 69.8% | 104.8% |
| Max drawdown | -59.6% (Apr 2026→Oct 2026) | -98.2% (Apr 2023→May 2025) |

## Peers (Biotechnology)
RYTM (Rhythm Pharmaceuticals, Inc.) USD 87.97 +1.57% · BLTE (Belite Bio, Inc) USD 152.62 +0.49% · IOVA (Iovance Biotherapeutics, Inc.) USD 14.72 +1.52% · PRAX (Praxis Precision Medicines, Inc) USD 248.24 +2.01% · IONS (Ionis Pharmaceuticals, Inc.) USD 44.12 +4.11% · SYRE (Spyre Therapeutics, Inc.) USD 80.1 -0.44%

## More
Full page: https://nexqual.com/OKUR · Free keyless MCP server with the same data and citations: https://mcp.nexqual.com/mcp · Guide for agents: https://nexqual.com/agents · https://nexqual.com/llms.txt