# Rydex Biotechnology Inv (RYOIX)

> Source: Nexqual · https://nexqual.com/RYOIX · data as of 2026-10-24 00:08 UTC · cite as "Nexqual, Rydex Biotechnology Inv (RYOIX), nexqual.com/RYOIX" · informational, not investment advice.

**Price:** USD 94.53 (-0.82% on the day) · last close of Oct 23, 2026; US market closed, not a live price. Prev close 95.31 · day 94.53–94.53 · 52w 72–98.74 · market cap null · NAS

## Key facts
- Total return with dividends: 1Y +37.3% vs S&P 500 +13.4%; 5Y +46.2% vs S&P 500 +76.9%.

## Total return (dividends reinvested)
|  | 1Y (from 2025-10-24) | 5Y (from 2021-10-25) |
|---|---|---|
| Total return | +37.3% | +46.2% |
| S&P 500 (SPY) | +13.4% | +76.9% |
| Per year | +37.5% | +7.9% |
| Volatility (annualized) | 22.0% | 23.0% |
| Max drawdown | -8.4% (Feb 2026→Mar 2026) | -27.3% (Nov 2021→Jun 2022) |

## Peers
RYHIX (Rydex Series Trust Health Care ) USD 160.39 +0.00% · RYTIX (Rydex Series Trust Technology F) USD 327.49 +0.00% · RYSIX (Rydex Series Trust Electronics ) USD 831.42 +0.00% · RYFIX (Rydex Series Trust Financial Se) USD 109.31 +0.00% · RYVIX (Rydex Series Trust Energy Servi) USD 309.32 -0.00%

## More
Full page: https://nexqual.com/RYOIX · Free keyless MCP server with the same data and citations: https://mcp.nexqual.com/mcp · Guide for agents: https://nexqual.com/agents · https://nexqual.com/llms.txt