# ALPS Medical Breakthroughs ETF (SBIO)

> Source: Nexqual · https://nexqual.com/SBIO · data as of 2026-10-23 19:49 UTC · cite as "Nexqual, ALPS Medical Breakthroughs ETF (SBIO), nexqual.com/SBIO" · informational, not investment advice.

**Price:** USD 53.38 (-2.14% on the day) · last close of Oct 23, 2026; US market after hours, not a live price. Prev close 54.55 · day 52.89–53.79 · 52w 42.4–70.85 · market cap null · PCX

## Key facts
- Total return with dividends: 1Y +25.7% vs S&P 500 +13.4%; 5Y +20.3% vs S&P 500 +76.9%.

## Total return (dividends reinvested)
|  | 1Y (from 2025-10-24) | 5Y (from 2021-10-25) |
|---|---|---|
| Total return | +25.7% | +20.3% |
| S&P 500 (SPY) | +13.4% | +76.9% |
| Per year | +25.8% | +3.8% |
| Volatility (annualized) | 32.5% | 33.2% |
| Max drawdown | -29.2% (Aug 2026→Oct 2026) | -51.5% (Nov 2021→Oct 2023) |

## Peers
BBC (Virtus Biotech Clinical Trials ) USD 41.22 -2.16% · BBP (Virtus Biotech ETF) USD 102.07 -1.82% · FBT (First Trust Amex Biotech Index ) USD 269.25 -1.26% · ROM (ProShares Ultra Technology) USD 138.19 +0.91% · KBA (KraneShares Bosera MSCI China A) USD 28.81 +1.10%

## More
Full page: https://nexqual.com/SBIO · Free keyless MCP server with the same data and citations: https://mcp.nexqual.com/mcp · Guide for agents: https://nexqual.com/agents · https://nexqual.com/llms.txt