# Senti Biosciences Holdings, Inc. (SNTI)

> Source: Nexqual · https://nexqual.com/SNTI · data as of 2026-10-15 20:00 UTC · cite as "Nexqual, Senti Biosciences Holdings, Inc. (SNTI), nexqual.com/SNTI" · informational, not investment advice.

**Price:** USD 0.26 (+8.60% on the day) · last close of Oct 15, 2026; US market closed, not a live price. Prev close 0.26 · day 0.24–0.26 · 52w 0.24–2.88 · market cap null · NCM

## Key facts
- Total return with dividends: 1Y -88.0% vs S&P 500 +18.1%; 5Y -99.7% vs S&P 500 +85.1%.

## Total return (dividends reinvested)
|  | 1Y (from 2025-10-16) | 5Y (from 2021-10-11) |
|---|---|---|
| Total return | -88.0% | -99.7% |
| S&P 500 (SPY) | +18.1% | +85.1% |
| Per year | -88.1% | -69.4% |
| Volatility (annualized) | 108.0% | 124.4% |
| Max drawdown | -89.9% (Dec 2025→Oct 2026) | -99.7% (Oct 2021→Oct 2026) |

## Peers (Biotechnology)
RYTM (Rhythm Pharmaceuticals, Inc.) USD 87.97 +1.57% · BLTE (Belite Bio, Inc) USD 152.62 +0.49% · IOVA (Iovance Biotherapeutics, Inc.) USD 14.72 +1.52% · PRAX (Praxis Precision Medicines, Inc) USD 248.24 +2.01% · IONS (Ionis Pharmaceuticals, Inc.) USD 44.12 +4.11% · SYRE (Spyre Therapeutics, Inc.) USD 80.1 -0.44%

## More
Full page: https://nexqual.com/SNTI · Free keyless MCP server with the same data and citations: https://mcp.nexqual.com/mcp · Guide for agents: https://nexqual.com/agents · https://nexqual.com/llms.txt