Alkermes plc (ALKS) Stock Price & Analysis

Alkermes plc (ALKS) closed at USD 44.18 on Thursday, October 22, 2026, up 1.61% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 43.48; the Oct 22, 2026 session ranged USD 43.46–44.68 on volume of 1,833,975 shares. Market capitalization is $7.41B, with a 52-week range of USD 27–55.67 (NMS). Source: Nexqual, retrieved October 23, 2026 at 11:23 UTC.

Also available as compact Markdown for AI agents: nexqual.com/ALKS.md

Key facts (ALKS)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (ALKS)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$1.17B$1.11B$1.66B$1.56B$1.48B$1.67B
Gross profit$976M$894M$1.41B$1.31B$1.28B—
Operating income$97.7M-$6.1M$414M$421M$254M$117M
Net income-$48.2M-$158M$356M$367M$242M$66.1M
EPS (diluted)-$0.29-$0.97$2.10$2.17$1.43—
Free cash flow$73.7M-$17.2M$353M$406M$480M$222M
Gross margin83.2%80.4%84.8%84.2%86.7%—
Operating margin8.3%-0.5%24.9%27.0%17.2%7.0%
Net margin-4.1%-14.2%21.4%23.6%16.4%4.0%
Revenue growth+13.0%-5.3%+49.6%-6.4%-5.2%—
Cash + short-term investments$536M$608M$773M$752M$588M—
Total debt$296M$293M$291M—$0K—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (ALKS)

P/E 112.1x · P/S 4.4x · EV/EBITDA 46.3x · EV/Sales 5.0x · P/FCF 33.4x · P/B 4.1x · FCF yield 2.99% · Earnings yield 0.89% · Net debt $868M · EV $8.28B

P/E at fiscal year-ends: Dec 2025 19.5x, Dec 2024 13.3x, Dec 2023 13.2x.

Insider sales (SEC Form 4, open-market, last ~7 months) (ALKS)

14 of 16 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-10-02Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$83K0.9%YesToo little history (no open-market trades in 2023–2025)
2026-09-03Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$98K0.9%YesToo little history (no open-market trades in 2023–2025)
2026-09-01Hopkinson Craig C.EVP R&D, Chief Medical Officer9,000$423K12.1%YesToo little history (no open-market trades in 2023)
2026-08-17Nichols Christian ToddSVP, Chief Commercial Officer7,576$373K6.9%YesOpportunistic (traded every year 2023–2025, no repeating month)
2026-08-03Snyderman Nancy Lynn MdDirector44,472$2.2M55.1%NoToo little history (no open-market trades in 2023–2025)
2026-08-03Hopkinson Craig C.EVP R&D, Chief Medical Officer9,000$437K11.5%YesToo little history (no open-market trades in 2023)
2026-08-03Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$99K0.9%YesToo little history (no open-market trades in 2023–2025)
2026-07-06Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$110K0.9%YesToo little history (no open-market trades in 2023–2025)
2026-07-01Hopkinson Craig C.EVP R&D, Chief Medical Officer9,000$464K10.9%YesToo little history (no open-market trades in 2023)
2026-06-12Wright Christopher IDirector2,000$90K7.2%YesToo little history (no open-market trades in 2023–2025)
2026-06-04Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$88K0.9%YesToo little history (no open-market trades in 2023–2025)
2026-06-01Hopkinson Craig C.EVP R&D, Chief Medical Officer9,000$375K10.4%YesToo little history (no open-market trades in 2023)
2026-05-29Parisi Samuel JosephVP, Finance (Interim PAO)16,217$687K67.8%NoToo little history (no open-market trades in 2023)
2026-05-04Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$68K0.9%YesToo little history (no open-market trades in 2023–2025)
2026-05-01Hopkinson Craig C.EVP R&D, Chief Medical Officer9,000$301K10%YesToo little history (no open-market trades in 2023)
2026-04-06Gaffin David JosephEVP, CLO, Alkermes, Inc.2,034$70K0.9%YesToo little history (no open-market trades in 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (ALKS)

Consensus Buy (mean 2.20 on a 1–5 scale), 20 analysts; mean target USD 56.21 (low 38, high 83).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-09-22RBC CapitalReiteratedOutperform$56
2026-09-22BairdTarget raisedOutperform$58 → $61
2026-09-21NeedhamReiteratedBuy$62
2026-07-29JP MorganTarget raisedNeutral$60 → $61
2026-07-29BairdTarget raisedOutperform$48 → $58
2026-07-28Piper SandlerTarget raisedOverweight$43 → $65
2026-07-20StifelTarget raisedBuy$45 → $63
2026-07-13NeedhamTarget raisedBuy$61 → $62
2026-07-02MizuhoTarget raisedOutperform$53 → $65
2026-06-29Wells FargoTarget raisedOverweight$44 → $65
2026-06-29B of A SecuritiesDowngradeNeutral → Underperform$38

Total return (dividends reinvested) (ALKS)

1Y (from 2025-10-23)5Y (from 2021-10-18)
Total return+47.1%+43.2%
S&P 500 (SPY)+14.9%+80.3%
Per year+47.3%+7.4%
Volatility (annualized)40.2%36.8%
Max drawdown-29.2% (Jul 2026→Oct 2026)-30.5% (Jul 2022→Oct 2022)

ALKS revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Product$411.7M83.0%+34.0%
— Vivitrol (part of Product)$124.5M25.1%+2.3%
— Aristada & Aristada Initio (part of Product)$96.7M19.5%-4.5%
— LUMRYZ (part of Product)$96.6M19.5%—
— LYBALVI (part of Product)$94.0M18.9%+11.5%
Manufactured Product & Royalty$84.3M17.0%+1.0%
— Royalty (part of Manufactured Product & Royalty)$63.4M12.8%-5.2%
— Manufacturing Revenue (part of Manufactured Product & Royalty)$20.9M4.2%+26.2%
Total revenue$496.0M100%—

ALKS revenue by region (fiscal year ended Dec 31, 2025)

LineRevenueShare of totalYoY
United States$1.37B93.0%-2.7%
Foreign Country Excluding Specified Country$102.4M6.9%-30.0%
Ireland$754,0000.1%-41.7%
Total revenue$1.48B100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

ALKS suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
SupplierNovo Nordisk (NVO)“In May 2024, we completed the sale of our Athlone Facility and related business to Novo Nordisk ("Novo") and entered into subcontracting arrangements to continue certain development and manufacturing activities performed at the Athlone Facility for a period of time after the closing of the transaction, which concluded by the end of 2025.”
PartnerJanssen“Under an exclusive license agreement with Janssen, we provided Janssen with rights to, and know-how, training and technical assistance in respect of, our small particle pharmaceutical compound technology, known as NANOCRYSTAL technology, which was used to develop the long-acting INVEGA products, and we received milestone payments from Janssen upon the achievement of certain development goals.”
PartnerAvadel Pharmaceuticals“In October 2025, we entered into the Transaction Agreement with Avadel, which was subsequently amended in November 2025, pursuant to which we agreed to acquire the entire issued and to be issued ordinary share capital of Avadel for consideration of (i) $21.00 per Avadel Share, payable in cash at closing and (ii) a non-transferable CVR entitling holders of Avadel Shares to a potential additional cash payment of $1.…”
CompetitorEli Lilly (LLY)“In the treatment of schizophrenia, ARISTADA, the long-acting INVEGA products and RISPERDAL CONSTA compete with each other and a number of other injectable products, including ZYPREXA RELPREVV ((olanzapine) For Extended Release Injectable Suspension), which is marketed and sold by Lilly;”
CompetitorJohnson & Johnson (JNJ)“In the treatment of schizophrenia, LYBALVI competes with other oral antipsychotic products, including CAPLYTA (lumateperone) marketed by Johnson & Johnson or its affiliated companies.;”

Quoted from the company's 10-K filed Feb 25, 2026.

Companies that name ALKS in their SEC reports

Relationship to ALKSCompanyFilingSentence
supplierVEEVA SYSTEMS INC (VEEV)10-K Mar 20, 2026“Our life sciences customers range from the largest global pharmaceutical and biotechnology companies such as Bayer AG, Boehringer Ingelheim GmbH, Eli Lilly and Company, Gilead Sciences, Inc., Merck Sharp & Dohme Corp., and Novartis Pharma AG, to emerging growth pharmaceutical and biotechnology companies, including Alkermes Inc., Alnylam Pharmaceuticals, Inc., bluebird bio, Inc., and Idorsia Pharmaceuticals Ltd. We…”

ALKS customer concentration

In the period ended Dec 31, 2025, 3 direct customers each accounted for at least 10% (31%, 20%, 17%) of revenue, per the company's 10-K filed Feb 25, 2026. The company does not name them.

ALKS analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$0.25$0.36-31.6%$465.1M4
Next quarter (ends Dec 2026)$0.09$0.32-72.0%$472.3M4
Current fiscal year (ends Dec 2026)$1.27$0.98+29.6%$1.82B4
Next fiscal year (ends Dec 2027)$1.81$1.56+16.2%$1.94B4

ALKS options: expected move

Options price a move of about ±11.0% (±$4.85) by Nov 20, 2026, which includes earnings on Nov 3, 2026. Over the last 8 reports the stock moved ±6.1% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262848.8%±11.0%
Dec 18, 20265650.7%±15.9%
Jan 15, 20278449.3%±19.1%
Feb 19, 202711949.6%±22.5%
May 21, 202721051.6%±30.7%

30-day implied volatility 48% vs 38.4% realized over the last 30 trading days. Put/call ratio (volume) 0.06. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 23, 2026 at 11:23 UTC)

PriceUSD 44.18
Change▲ 1.61% (up)
Previous CloseUSD 43.48
OpenUSD 44
Day RangeUSD 43.46 – 44.68
52-Week RangeUSD 27 – 55.67
Volume1,833,975 shares
Market Cap$7.41B
ExchangeNMS

Technical Analysis (ALKS)

Nexqual's technical model rates ALKS "NEUTRAL" based on 3 bullish and 4 bearish signals across 127 daily candles, as of October 23, 2026 at 11:23 UTC.

Overall SignalNEUTRAL
RSI (14)57.22 (neutral)
vs SMA50Below (USD 44.61)
MACD-0.35 (negative)

Analyst Ratings (ALKS)

Wall Street analysts rate ALKS "Buy" based on 20 analysts, with a mean price target of USD 56.21 (range USD 38–83), per Nexqual as of October 23, 2026 at 11:23 UTC.

Consensus RatingBuy
Analyst Count20
Mean TargetUSD 56.21
High TargetUSD 83
Low TargetUSD 38
Buy / Hold / Sell15 / 4 / 1

Earnings (ALKS)

Next Earnings Date2026-11-03
EPS EstimateUSD 0.25
Revenue Estimate$465.11M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 0.7 vs est 0.29 ▲ beat
2026-03-31USD 0.38 vs est -0.04 ▲ beat
2025-12-31USD 0.48 vs est 0.45 ▲ beat
2025-09-30USD 0.65 vs est 0.39 ▲ beat

Source: Nexqual, October 23, 2026 at 11:23 UTC.

Financials & Fundamentals (ALKS)

Total Revenue$1.67B
Revenue Growth (latest quarter, YoY)+27.00%
Gross Margin+87.18%
Operating Margin+15.50%
Profit Margin+3.96%
ROE+3.85%
Debt / Equity0.87
Current Ratio2.3
Total Cash$656.58M
Total Debt$1.57B
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)$221.65M (13.3% of revenue)

Source: Nexqual, October 23, 2026 at 11:23 UTC.

Financial Health Score (ALKS)

Nexqual rates Alkermes plc's overall financial health "Mixed" across five dimensions, as of October 23, 2026 at 11:23 UTC.

GrowthWeak — Revenue -5% YoY (annual), declining
ProfitabilityStrong — Gross margin 87%, operating 15% (last 12 months)
Balance SheetMixed — $657M cash and investments vs $1.52B debt (Jun 2026, SEC)
Cash FlowSolid — FCF $222M (last 4 quarters to Jun 2026, SEC), 13% margin
EfficiencyWeak — ROE 4%, ROA 4.2%

Ownership (ALKS)

Insider Ownership+1.40%
Institutional Ownership+107.78%
Shares Outstanding167.76M
Float155.19M
Short % of Float+14.72%

Source: Nexqual, October 23, 2026 at 11:23 UTC.

Leadership (ALKS)

Alkermes plc is led by Blair C. Jackson, President, CEO & Director, per Nexqual as of October 23, 2026 at 11:23 UTC.

President, CEO & DirectorBlair C. Jackson
Senior VP & CFOJoshua Reed
Senior Vice President of Corporate Affairs & Investor RelationsSandra Coombs

Major Backers & Investors (ALKS)

Notable institutional backers of Alkermes plc include Baker Bros. Advisors, LP, Price (T.Rowe) Associates Inc, Renaissance Technologies, according to Nexqual as of October 23, 2026 at 11:23 UTC.

Active Investors

InvestorStake
Baker Bros. Advisors, LP5.97%
Price (T.Rowe) Associates Inc4.02%
Renaissance Technologies3.85%
Deep Track Capital, Lp2.38%
Fidelity1.09%

Index Funds (Passive)

FundStake
BlackRock17.43%
Vanguard Group10.14%
State Street5.46%
Geode Capital2.67%
Dimensional Fund Advisors2.5%

Source: Nexqual, October 23, 2026 at 11:23 UTC.

From Alkermes plc's Latest SEC 10-K Filing (filed 2026-02-25)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

SymbolNamePriceChange
AMRXAmneal Pharmaceuticals, Inc.USD 20.48▲ 1.39%
HIMSHims & Hers Health, Inc.USD 29.13▼ 0.27%
LNTHLantheus Holdings, Inc.USD 100.1▼ 0.14%
KNSAKiniksa Pharmaceuticals InternaUSD 80.79▲ 1.37%
RDYDr. Reddy's Laboratories LtdUSD 13.23▲ 0.3%
RGCRegencell Bioscience Holdings LUSD 9.81▼ 9.17%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 11:23 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt