Amgen Inc. (AMGN) Stock Price & Analysis

Amgen Inc. (AMGN) closed at USD 447.28 on Thursday, October 22, 2026, up 2.04% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 438.34; the Oct 22, 2026 session ranged USD 437.19–450.98 on volume of 3,103,849 shares. Market capitalization is $241.81B, with a 52-week range of USD 288–450.98 (NMS). Source: Nexqual, retrieved October 23, 2026 at 09:26 UTC.

Also available as compact Markdown for AI agents: nexqual.com/AMGN.md

Key facts (AMGN)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (AMGN)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$26.0B$26.3B$28.2B$33.4B$36.8B$38.1B
Gross profit$19.5B$19.9B$19.7B$20.6B$24.7B—
Operating income$7.64B$9.57B$7.90B$7.26B$9.08B$11.4B
Net income$5.89B$6.55B$6.72B$4.09B$7.71B$8.74B
EPS (diluted)$10.28$12.11$12.49$7.56$14.23—
Free cash flow$8.38B$8.79B$7.36B$10.4B$8.10B$10.2B
Gross margin75.2%75.7%70.0%61.5%67.2%—
Operating margin29.4%36.3%28.0%21.7%24.7%30.0%
Net margin22.7%24.9%23.8%12.2%21.0%23.0%
Revenue growth+2.2%+1.3%+7.1%+18.6%+10.0%—
Cash + short-term investments$8.04B$9.30B$10.9B———
Total debt$33.3B$38.9B$64.6B$60.1B$54.6B—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (AMGN)

P/E 27.7x · P/S 6.3x · EV/EBITDA 20.2x · EV/Sales 7.5x · P/FCF 23.8x · P/B 20.7x · FCF yield 4.21% · Earnings yield 3.62% · Dividend yield (paid, TTM) 2.19% · Net debt $43.3B · EV $285B

P/E at fiscal year-ends: Dec 2025 23.0x, Dec 2024 34.5x, Dec 2023 23.1x.

Superinvestors (SEC 13F-HR, Q2 2026) (AMGN)

4 of 80 tracked investors hold AMGN (1 investor on Q3 2026, filed early). Each row is the investor's latest 13F; change is vs their prior-quarter share count.

InvestorFirm% of portfolioValueChangeQuarter
Torray Funds2.92%$21.6MAdded +10.7%Q2 2026
David KatzMatrix Asset Advisors2.91%$35.4MReduced -18.4%Q3 2026
Mairs & PowerMairs & Power Funds0.02%$1.8MReduced -0.8%Q2 2026
Dodge & Cox FundsDodge & Cox<0.01%$4.6MReduced -4.1%Q2 2026

Analysts (AMGN)

Consensus Hold (mean 2.74 on a 1–5 scale), 34 analysts; mean target USD 396.7 (low 225, high 500).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-21BarclaysTarget raisedEqual-Weight$380 → $400
2026-10-13GuggenheimTarget loweredNeutral$388 → $378
2026-10-12BMO CapitalTarget loweredMarket Perform$450 → $415
2026-10-12Wells FargoTarget loweredEqual-Weight$435 → $430
2026-10-09UBSTarget raisedBuy$430 → $470
2026-10-08RBC CapitalTarget raisedOutperform$400 → $430
2026-10-08Cantor FitzgeraldTarget raisedNeutral$400 → $440
2026-10-07Truist SecuritiesTarget raisedHold$362 → $380
2026-10-07Morgan StanleyTarget loweredEqual-Weight$362 → $359
2026-09-29ScotiabankTarget raisedSector Outperform$450 → $500
2026-09-10HSBCDowngradeBuy → Hold$445 → $425
2026-09-08BMO CapitalDowngradeOutperform → Market Perform$450

Total return (dividends reinvested) (AMGN)

1Y (from 2025-10-23)5Y (from 2021-10-18)
Total return+57.0%+149.8%
S&P 500 (SPY)+14.9%+80.3%
Per year+57.2%+20.0%
Volatility (annualized)29.6%25.3%
Max drawdown-16.6% (Feb 2026→May 2026)-23.1% (Nov 2022→May 2023)

Companies that name AMGN in their SEC reports

Relationship to AMGNCompanyFilingSentence
partnerNeumora Therapeutics, Inc. (NMRA)10-K Mar 30, 2026“Until a specified period of time following the achievement of the first successful Phase 2 clinical trial for any licensed product, if we choose to sell, transfer, sublicense or divest rights to a licensed product in certain major markets, Amgen has a time-limited, exclusive right of first negotiation to enter into an agreement with us for such rights.”
partnerJasper Therapeutics, Inc. (JSPR)10-K Mar 30, 2026“have an exclusive license agreement with Amgen Inc. ("Amgen") for the development and commercialization of the briquilimab”
partnerCytomX Therapeutics, Inc. (CTMX)10-K Mar 16, 2026“We currently have several strategic alliances with major multinational drug companies, including Amgen, Inc. ("Amgen"), Bristol Myers Squibb, Astellas Pharma Inc. ("Astellas"), Regeneron Pharmaceuticals Inc. ("Regeneron"), and ModernaTX, Inc., a wholly owned subsidiary of Moderna, Inc ("Moderna").”
partnerQ32 Bio Inc. (QTTB)10-K Mar 10, 2026“Following the acquisition, Legacy Q32 agreed with Amgen to mutually terminate the Collaboration and Option Agreement (the "Horizon Collaboration Agreement") and the Asset Purchase Agreement (the "Purchase Agreement", and together with the Horizon Collaboration Agreement, the "Horizon Agreements"), each between Legacy Q32 and Horizon Therapeutics Ireland DAC ("Horizon").”
partnerVerastem, Inc. (VSTM)10-K Mar 4, 2026“In September 2021, we entered into a clinical collaboration agreement with Amgen, Inc. ("Amgen") to evaluate avutometinib in combination with Amgen's KRAS G12C inhibitor LUMAKRAS® (sotorasib) with and without defactinib in a Phase1/2 study entitled RAMP 203 in patients naïve to or previously treated with a KRAS G12C inhibitor.”
partnerTScan Therapeutics, Inc. (TCRX)10-K Mar 4, 2026“In addition, the Company is continuing to discover targets for Crohn's disease in partnership with Amgen.”
relatedZymeworks Inc. (ZYME)10-K Mar 2, 2026“Dr. Cesano has also held various management positions at Amgen Inc., Biogen Inc. (formerly Biogen Idec) and SmithKline Beecham Pharmaceuticals, where she helped to advance various oncology drugs through late-stage development and FDA approvals.”
partnerBeOne Medicines Ltd. (ONC)10-K Feb 26, 2026“On October 31, 2019, our wholly-owned subsidiary, BeOne Medicines I GmbH, entered into a Collaboration Agreement with Amgen, which became effective on January 2, 2020 (as amended, the "Amgen Collaboration Agreement").”
partnerRevolution Medicines, Inc. (RVMD)10-K Feb 25, 2026“In February 2025, we entered into a clinical collaboration with Amgen Inc. (Amgen) pursuant to which Amgen is evaluating its compound AMG 193, an MTA-cooperative PRMT5 inhibitor, in combination with daraxonrasib in patients with 2L PDAC as part of an Amgen-sponsored trial.”
partnerXencor Inc (XNCR)10-K Feb 25, 2026“Amgen: Xaluritamig is a STEAP1 x CD3 2+1 XmAb bispecific T-cell engager that our partner Amgen is advancing for the treatment of patients with prostate cancer.”
partnerGENMAB A/S (GMAB)20-F Feb 17, 2026“Roche / Amgen Teprotumumab Collaboration”
partnerALNYLAM PHARMACEUTICALS, INC. (ALNY)10-K Feb 12, 2026“Companies working on chemically synthesized siRNAs include but are not limited to ADARx Pharmaceuticals, Inc., or ADARx, Amgen Inc., Argo Biopharmaceutical Co., Ltd., or Argo, Aro Biotherapeutics, Arrowhead Pharmaceuticals, Inc., or Arrowhead, AstraZeneca plc, or AstraZeneca, Dyne Therapeutics, Inc., Eli Lilly and Company, GlaxoSmithKline plc, Novartis, Novo Nordisk A/S, or Novo Nordisk, SanegeneBio, Sarepta Thera…”
partnerARROWHEAD PHARMACEUTICALS, INC. (ARWR)10-K Nov 25, 2025“The Company has entered into multiple license and collaboration agreements with leading biotech and pharmaceutical companies, including Sarepta Therapeutics, Inc., Amgen Inc., Takeda Pharmaceutical Company Limited, Glaxosmithkline Intellectual Property (No. 3) Limited and Novartis Pharma AG, for programs that the Company does not intend to commercialize independently.”
customerDAXOR CORP (DXR)10-K Mar 28, 2012“manufactured by Amgen) to stimulate rapid red cell replacement; (c) if the patient is suitable for blood donation, remove one unit”

AMGN analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$5.79$5.74+0.8%$10.08B28
Next quarter (ends Dec 2026)$5.77$5.77+0.1%$10.27B26
Current fiscal year (ends Dec 2026)$23.03$22.34+3.1%$38.97B33
Next fiscal year (ends Dec 2027)$24.49$23.46+4.4%$40.38B31

Key Statistics (as of October 23, 2026 at 09:26 UTC)

PriceUSD 447.28
Change▲ 2.04% (up)
Previous CloseUSD 438.34
OpenUSD 441.55
Day RangeUSD 437.19 – 450.98
52-Week RangeUSD 288 – 450.98
Volume3,103,849 shares
Market Cap$241.81B
ExchangeNMS

Technical Analysis (AMGN)

Nexqual's technical model rates AMGN "BUY" based on 5 bullish and 2 bearish signals across 127 daily candles, as of October 23, 2026 at 09:26 UTC.

Overall SignalBUY
RSI (14)61.22 (neutral)
vs SMA50Above (USD 416.83)
MACD8.63 (positive)

Analyst Ratings (AMGN)

Wall Street analysts rate AMGN "Hold" based on 34 analysts, with a mean price target of USD 396.7 (range USD 225–500), per Nexqual as of October 23, 2026 at 09:26 UTC.

Consensus RatingHold
Analyst Count34
Mean TargetUSD 396.7
High TargetUSD 500
Low TargetUSD 225
Buy / Hold / Sell12 / 17 / 5

Earnings (AMGN)

Next Earnings Date2026-11-03
EPS EstimateUSD 5.79
Revenue Estimate$10.08B

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 6.29 vs est 5.62 ▲ beat
2026-03-31USD 5.15 vs est 4.77 ▲ beat
2025-12-31USD 5.29 vs est 4.73 ▲ beat
2025-09-30USD 5.64 vs est 5.01 ▲ beat

Source: Nexqual, October 23, 2026 at 09:26 UTC.

Financials & Fundamentals (AMGN)

Total Revenue$38.09B
Revenue Growth (latest quarter, YoY)+9.50%
Gross Margin+71.89%
Operating Margin+35.55%
Profit Margin+22.95%
ROE+91.47%
Debt / Equity4.9
Current Ratio1.37
Total Cash$13.99B
Total Debt$57.30B
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)$10.18B (26.7% of revenue)

Source: Nexqual, October 23, 2026 at 09:26 UTC.

Financial Health Score (AMGN)

Nexqual rates Amgen Inc.'s overall financial health "Solid" across five dimensions, as of October 23, 2026 at 09:26 UTC.

GrowthSolid — Revenue +10% YoY (annual)
ProfitabilityStrong — Gross margin 72%, operating 36% (last 12 months)
Balance SheetCritical — $14.0B cash and investments vs $57.3B debt (Jun 2026, SEC)
Cash FlowStrong — FCF $10.2B (last 4 quarters to Jun 2026, SEC), 27% margin
EfficiencyStrong — ROE 91%, ROA 8.7%

Ownership (AMGN)

Insider Ownership+0.23%
Institutional Ownership+85.17%
Shares Outstanding540.63M
Float539.16M
Short % of Float+2.60%

Source: Nexqual, October 23, 2026 at 09:26 UTC.

Leadership (AMGN)

Amgen Inc. is led by Robert A. Bradway, Chairman & CEO, per Nexqual as of October 23, 2026 at 09:26 UTC.

Chairman & CEORobert A. Bradway
Executive Vice President of Global Markets and PolicyMurdo Gordon
Executive Vice PresidentPeter H. Griffith
Executive VP & CFOThomas J. W. Dittrich
Executive Vice President of OperationsEsteban Santos

Major Backers & Investors (AMGN)

Notable institutional backers of Amgen Inc. include Capital Group, Invesco, Charles Schwab Investment Management, Inc., according to Nexqual as of October 23, 2026 at 09:26 UTC.

Active Investors

InvestorStake
Capital Group5.38%
Invesco3.02%
Charles Schwab Investment Management, Inc.2.78%
Morgan Stanley2.53%
Charles Schwab1.81%
Wells Fargo & Company1.34%

Index Funds (Passive)

FundStake
Vanguard Group9.27%
BlackRock9.13%
State Street5.65%
Geode Capital2.9%

Source: Nexqual, October 23, 2026 at 09:26 UTC.

Peers & Related Stocks

SymbolNamePriceChange
AZNAstraZeneca PLCUSD 172.57▲ 2.45%
NVSNovartis AGUSD 156.27▲ 1.52%
GILDGilead Sciences, Inc.USD 157.19▲ 2.36%
NVONovo Nordisk A/SUSD 39.43▲ 0.95%
PFEPfizer, Inc.USD 30.42▲ 1.91%
MRKMerck & Company, Inc.USD 147.24▼ 1.76%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 09:26 UTC. This page is informational and not investment advice.

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