Castle Biosciences Inc (CSTL) Stock Price & Analysis

Castle Biosciences Inc (CSTL) fell 3.12% to USD 24.69 as of July 25, 2026 at 08:27 UTC, according to Nexqual real-time market data.

CSTL last closed at USD 25.48; the session ranged USD 24.35–25.63 on volume of 393,431 shares. Market capitalization is $748.69M, with a 52-week range of USD 14.59–44.28 (NGM). Source: Nexqual, July 25, 2026 at 08:27 UTC.

Key Statistics (as of July 25, 2026 at 08:27 UTC)

PriceUSD 24.69
Change▼ 3.12% (down)
Previous CloseUSD 25.48
OpenUSD 25.58
Day RangeUSD 24.35 – 25.63
52-Week RangeUSD 14.59 – 44.28
Volume393,431 shares
Market Cap$748.69M
ExchangeNGM

Technical Analysis (CSTL)

Nexqual's technical model rates CSTL "STRONG BUY" based on 5 bullish and 0 bearish signals across 125 daily candles, as of July 25, 2026 at 08:27 UTC.

Overall SignalSTRONG BUY
RSI (14)59.21 (neutral)
vs SMA50Above (USD 22.01)
MACD0.69 (positive)

Analyst Ratings (CSTL)

Wall Street analysts rate CSTL "Strong Buy" based on 9 analysts, with a mean price target of USD 42.78 (range USD 35–52), per Nexqual as of July 25, 2026 at 08:27 UTC.

Consensus RatingStrong Buy
Analyst Count9
Mean TargetUSD 42.78
High TargetUSD 52
Low TargetUSD 35
Buy / Hold / Sell9 / 0 / 0

Earnings (CSTL)

Next Earnings Date2026-07-30
EPS EstimateUSD -0.41
Revenue Estimate$86.24M

Recent Earnings History

QuarterActual vs Estimate
2026-03-31USD -0.49 vs est -0.49 ▼ miss
2025-12-31USD -0.08 vs est -0.26 ▲ beat
2025-09-30USD -0.02 vs est -0.51 ▲ beat
2025-06-30USD 0.15 vs est -0.5 ▲ beat

Source: Nexqual, July 25, 2026 at 08:27 UTC.

Financials & Fundamentals (CSTL)

Total Revenue$339.92M
Revenue Growth (YoY)-4.90%
Gross Margin+77.88%
Operating Margin-22.00%
Profit Margin-3.78%
ROE-2.85%
Debt / Equity7.96
Current Ratio6.75
Total Cash$261.68M
Total Debt$36.72M
Free Cash Flow$12.89M

Source: Nexqual, July 25, 2026 at 08:27 UTC.

Financial Health Score (CSTL)

Nexqual rates Castle Biosciences Inc's overall financial health "Mixed" across five dimensions, as of July 25, 2026 at 08:27 UTC.

GrowthMixed — Revenue +3.7% YoY (annual), slow
ProfitabilitySolid — Gross margin 78%, operating -22%
Balance SheetStrong — $262M cash vs $37M debt, net cash position
Cash FlowMixed — FCF $13M, slim 3.7% margin
EfficiencyCritical — ROE -3%, ROA -4.0%

Ownership (CSTL)

Insider Ownership+2.73%
Institutional Ownership+92.54%
Shares Outstanding30.33M
Float26.79M
Short % of Float+4.80%

Source: Nexqual, July 25, 2026 at 08:27 UTC.

Leadership (CSTL)

Castle Biosciences Inc is led by Derek J. Maetzold (age 63), Founder, CEO, President & Director, per Nexqual as of July 25, 2026 at 08:27 UTC.

Founder, CEO, President & DirectorDerek J. Maetzold (age 63)
CFO & TreasurerFrank Stokes (age 55)
Chief Operating OfficerKristen M. Oelschlager R.N. (age 56)
Vice President of Investor Relations & Corporate AffairsCamilla Zuckero
Vice President of SalesKevin Doman

Major Backers & Investors (CSTL)

Notable institutional backers of Castle Biosciences Inc include RTW Investments LP, Principal Financial Group, Inc., Portolan Capital Management, LLC, according to Nexqual as of July 25, 2026 at 08:27 UTC.

Active Investors

InvestorStake
RTW Investments LP9.09%
Principal Financial Group, Inc.5.84%
Portolan Capital Management, LLC4.45%
Summit Partners Public Asset Management LLC3.1%
Principal Funds, Inc-SmallCap Fund2.34%

Index Funds (Passive)

FundStake
BlackRock12.91%
Vanguard Group11.42%
Dimensional Fund Advisors3.43%
Allianz Asset Management GmbH2.67%
State Street2.54%

Source: Nexqual, July 25, 2026 at 08:27 UTC.

From Castle Biosciences Inc's Latest SEC 10-K Filing (filed 2026-02-26)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

SymbolNamePriceChange
PSNLPersonalis, Inc.USD 11.78▼ 5.53%
VCYTVeracyte, Inc.USD 56.61▼ 2.41%
CDNACareDx, Inc.USD 37.14▼ 1.69%
CDXSCodexis, Inc.USD 1.48▼ 28.16%
PHRPhreesia, Inc.USD 10.22▲ 2.1%

Data source: Nexqual — real-time market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: July 25, 2026 at 08:27 UTC. This page is informational and not investment advice.