Castle Biosciences Inc (CSTL) Stock Price & Analysis
Castle Biosciences Inc (CSTL) rose 4.77% to USD 21.08 as of June 10, 2026 at 03:29 UTC, according to Nexqual real-time market data.
CSTL last closed at USD 20.12; the session ranged USD 20.24–21.09 on volume of 253,553 shares. Market capitalization is $639.36M, with a 52-week range of USD 14.59–44.28 (NGM). Source: Nexqual, June 10, 2026 at 03:29 UTC.
Key Statistics (as of June 10, 2026 at 03:29 UTC)
| Price | USD 21.08 |
|---|---|
| Change | ▲ 4.77% (up) |
| Previous Close | USD 20.12 |
| Open | USD 20.3 |
| Day Range | USD 20.24 – 21.09 |
| 52-Week Range | USD 14.59 – 44.28 |
| Volume | 253,553 shares |
| Market Cap | $639.36M |
| Exchange | NGM |
Technical Analysis (CSTL)
Nexqual's technical model rates CSTL "NEUTRAL" based on 2 bullish and 3 bearish signals across 124 daily candles, as of June 10, 2026 at 03:29 UTC.
| Overall Signal | NEUTRAL |
|---|---|
| RSI (14) | 48 (neutral) |
| vs SMA50 | Below (USD 22.47) |
| MACD | -0.45 (negative) |
Analyst Ratings (CSTL)
Wall Street analysts rate CSTL "Strong Buy" based on 8 analysts, with a mean price target of USD 44 (range USD 35–52), per Nexqual as of June 10, 2026 at 03:29 UTC.
| Consensus Rating | Strong Buy |
|---|---|
| Analyst Count | 8 |
| Mean Target | USD 44 |
| High Target | USD 52 |
| Low Target | USD 35 |
| Buy / Hold / Sell | 8 / 0 / 0 |
Earnings (CSTL)
| Next Earnings Date | 2026-08-03 |
|---|---|
| EPS Estimate | USD -0.4 |
| Revenue Estimate | $86.26M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-03-31 | USD -0.49 vs est -0.49 ▼ miss |
| 2025-12-31 | USD -0.08 vs est -0.26 ▲ beat |
| 2025-09-30 | USD -0.02 vs est -0.51 ▲ beat |
| 2025-06-30 | USD 0.15 vs est -0.5 ▲ beat |
Source: Nexqual, June 10, 2026 at 03:29 UTC.
Financials & Fundamentals (CSTL)
| Total Revenue | $339.92M |
|---|---|
| Revenue Growth (YoY) | -4.90% |
| Gross Margin | +77.88% |
| Operating Margin | -22.00% |
| Profit Margin | -3.78% |
| ROE | -2.85% |
| Debt / Equity | 7.96 |
| Current Ratio | 6.75 |
| Total Cash | $261.68M |
| Total Debt | $36.72M |
| Free Cash Flow | $12.89M |
Source: Nexqual, June 10, 2026 at 03:29 UTC.
Financial Health Score (CSTL)
Nexqual rates Castle Biosciences Inc's overall financial health "Mixed" across five dimensions, as of June 10, 2026 at 03:29 UTC.
| Growth | Mixed — Revenue +3.7% YoY (annual), slow |
|---|---|
| Profitability | Solid — Gross margin 78%, operating -22% |
| Balance Sheet | Strong — $262M cash vs $37M debt, net cash position |
| Cash Flow | Mixed — FCF $13M, slim 3.7% margin |
| Efficiency | Critical — ROE -3%, ROA -4.0% |
Ownership (CSTL)
| Insider Ownership | +2.73% |
|---|---|
| Institutional Ownership | +93.02% |
| Shares Outstanding | 30.33M |
| Float | 26.77M |
| Short % of Float | +5.01% |
Source: Nexqual, June 10, 2026 at 03:29 UTC.
Leadership (CSTL)
Castle Biosciences Inc is led by Derek J. Maetzold (age 63), Founder, CEO, President & Director, per Nexqual as of June 10, 2026 at 03:29 UTC.
| Founder, CEO, President & Director | Derek J. Maetzold (age 63) |
|---|---|
| CFO & Treasurer | Frank Stokes (age 55) |
| Chief Operating Officer | Kristen M. Oelschlager R.N. (age 56) |
| Vice President of Investor Relations & Corporate Affairs | Camilla Zuckero |
| Vice President of Sales | Kevin Doman |
Major Backers & Investors (CSTL)
Notable institutional backers of Castle Biosciences Inc include RTW Investments LP, Principal Financial Group, Inc., Portolan Capital Management, LLC, according to Nexqual as of June 10, 2026 at 03:29 UTC.
Active Investors
| Investor | Stake |
|---|---|
| RTW Investments LP | 9.09% |
| Principal Financial Group, Inc. | 5.84% |
| Portolan Capital Management, LLC | 4.45% |
| Fidelity | 3.3% |
| Summit Partners Public Asset Management LLC | 3.1% |
| Principal Funds, Inc-SmallCap Fund | 2.67% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 12.88% |
| Vanguard Group | 11.42% |
| Dimensional Fund Advisors | 3.43% |
| Allianz Asset Management GmbH | 2.67% |
Source: Nexqual, June 10, 2026 at 03:29 UTC.
From Castle Biosciences Inc's Latest SEC 10-K Filing (filed 2026-02-26)
Key Strengths & Strategy (as disclosed to the SEC)
- Our proprietary tests, which were first marketed prior to May 6, 2024, remain approved by and under the oversight of the NYSDOH, and we continue to believe that changes in FDA's regulatory approach to LDTs will have no material impact on our existing test offerings.
- Medical Device Regulatory Framework Although we currently market our proprietary testing products as LDTs, which are currently subject to enforcement discretion, we could be subject to FDA compliance obligations in the future.
- DecisionDx-Melanoma DecisionDx-Melanoma is our proprietary risk stratification gene expression profile ("GEP") test designed to predict the likelihood of a positive sentinel lymph node and the risk of metastasis or recurrence for patients diagnosed with invasive cutaneous melanoma ("CM"), a deadly skin cancer.
- DecisionDx-SCC DecisionDx‑SCC is our proprietary GEP test designed for use in patients with cutaneous squamous cell carcinoma ("SCC"), the second most common form of skin cancer, with one or more risk factors (also referred to as "high-risk" SCC).
Partnerships
- If these suppliers can no longer provide us with the materials we need to perform our test services, they do not meet our quality specifications, or we cannot obtain acceptable substitute materials, our business would likely be negatively affected. 12 Table of Contents License Agreement with The Washington University In November 2009, we entered into a license agreement (the "License Agreement") with The Washington University in St.
- In June 2025, we entered into a collaboration and license agreement with SciBase Holding AB ("SciBase") to develop and commercialize diagnostic tests for dermatologic diseases, beginning with atopic dermatitis.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| PSNL | Personalis, Inc. | USD 9.75 | ▼ 9.3% |
| VCYT | Veracyte, Inc. | USD 49.24 | ▲ 1.05% |
| CDNA | CareDx, Inc. | USD 22.75 | ▲ 2.25% |
| CDXS | Codexis, Inc. | USD 2.47 | ▼ 3.52% |
| PHR | Phreesia, Inc. | USD 9.29 | ▼ 2.62% |
Data source: Nexqual — real-time market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: June 10, 2026 at 03:29 UTC. This page is informational and not investment advice.