GRAIL, Inc. (GRAL) Stock Price & Analysis

GRAIL, Inc. (GRAL) is trading at USD 159.72, up 1.16% today, as of October 29, 2026 at 17:21 UTC (US market open; quotes may be delayed), according to Nexqual market data.

GRAL last closed at USD 157.88; today's session has ranged USD 155.69–161.9 on volume of 285,252 shares. Market capitalization is $7.13B, with a 52-week range of USD 41.5–166.48 (NMS). Source: Nexqual, retrieved October 29, 2026 at 17:22 UTC.

Also available as compact Markdown for AI agents: nexqual.com/GRAL.md

Key facts (GRAL)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (GRAL)

USDFY2022FY2023FY2024FY2025TTM
Revenue$55.5M$93.1M$126M$147M$165M
Operating income-$5.44B-$1.52B-$2.19B-$562M-$559M
Net income-$5.40B-$1.47B-$2.03B-$408M-$392M
EPS (diluted)-$173.89-$47.21-$63.54-$11.11—
Free cash flow-$584M-$609M-$582M-$300M-$296M
Operating margin-9798.2%-1627.6%-1743.0%-382.0%-338.4%
Net margin-9719.3%-1574.2%-1613.9%-277.5%-236.9%
Revenue growth—+67.6%+34.9%+17.2%—
Cash + short-term investments$242M$97.3M$761M$902M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (GRAL)

P/S 43.2x · P/B 2.8x · FCF yield -4.15% · Earnings yield -5.49%

Insider sales (SEC Form 4, open-market, last ~7 months) (GRAL)

5 of 8 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-10-15Ofman Joshua J.Chief Executive Officer20,000$2.7M5.5%Yes (adopted December 2, 2025)Too little history (no open-market trades in 2023)
2026-10-05Partridge Andrew JohnChief Growth Officer7,873$1.2M4.8%NoToo little history (no open-market trades in 2023–2025)
2026-10-05Freidin AaronChief Financial Officer23,619$3.5M9.5%NoToo little history (no open-market trades in 2023)
2026-09-21Freidin AaronChief Financial Officer4,100$383K1.6%Yes (adopted December 11, 2025)Too little history (no open-market trades in 2023)
2026-09-21Ofman Joshua J.Chief Executive Officer61,452$6.0M14.5%Yes (adopted December 2, 2025)Too little history (no open-market trades in 2023)
2026-08-27Ofman Joshua J.Chief Executive Officer5,000$425K1.2%YesToo little history (no open-market trades in 2023)
2026-08-27Freidin AaronChief Financial Officer7,900$672K3%YesToo little history (no open-market trades in 2023)
2026-06-04Partridge Andrew JohnChief Growth Officer1,491$91K0.9%NoToo little history (no open-market trades in 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (GRAL)

Consensus Hold (mean 2.50 on a 1–5 scale), 10 analysts; mean target USD 132.56 (low 74, high 180).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-13Morgan StanleyTarget raisedEqual-Weight$60 → $120
2026-10-13TD CowenTarget raisedBuy$88 → $180
2026-10-02UBSTarget raisedBuy$105 → $175
2026-10-01GuggenheimTarget raisedBuy$75 → $155
2026-09-28Canaccord GenuityTarget raisedBuy$80 → $150
2026-09-25MizuhoTarget raisedNeutral$65 → $100
2026-09-22BairdTarget raisedOutperform$96 → $118
2026-09-17RBC CapitalInitiatedSector Perform$84
2026-09-09UBSInitiatedBuy$105
2026-07-15MizuhoTarget raisedNeutral$58 → $65

Total return (dividends reinvested) (GRAL)

1Y (from 2025-10-29)5Y (from 2024-06-10)
Total return+87.4%+992.4%
S&P 500 (SPY)+13.0%+78.9%
Per year+87.5%+172.4%
Volatility (annualized)111.0%101.4%
Max drawdown-62.9% (Jan 2026→Feb 2026)-61.0% (Nov 2025→Mar 2026)

GRAL earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 5, 2026Quarter ended Jun 30, 2026−$1.34−$2.43Beat +44.9%-12.8%
May 5, 2026Quarter ended Mar 31, 2026−$1.37−$1.96Beat +30.1%+12.7%
Feb 19, 2026Quarter ended Dec 31, 2025−$2.44−$2.53Beat +3.6%-50.9%
Jan 12, 2026Quarter ended Dec 31, 2025−$2.44−$2.53Beat +3.6%+1.9%
Nov 12, 2025Quarter ended Sep 30, 2025−$2.46−$3.26Beat +24.5%-0.2%
Oct 16, 2025Quarter ended Sep 30, 2025−$2.46−$3.26Beat +24.5%+3.3%
Aug 12, 2025————+3.9%
May 13, 2025————-8.6%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

GRAL recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 13, 2026Schedule 13G/AFarallon Capital Management, L.L.C., Farallon Capital Partners, L.P.: 9.6% of shares, passive 5%+ holder (amended)
Aug 7, 2026Schedule 13GSTATE STREET CORPORATION: 5.6% of shares, passive 5%+ holder
Aug 6, 2026Schedule 13G/APRIMECAP MANAGEMENT CO/CA/: 5.1% of shares, passive 5%+ holder (amended)
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 5, 20268-KQuarterly results
Jul 28, 2026Schedule 13G/ABlackRock, Inc.: 7.9% of shares, passive 5%+ holder (amended)

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

GRAL revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Screening revenue$42.6M95.4%+24.0%
Development Services$2.0M4.6%+75.5%
Total revenue$44.7M100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

GRAL suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
SupplierILLUMINA, INC. (ILMN)“•We rely on Illumina, Inc. as a sole supplier for our next-generation sequencers and associated reagents, Madison Industries as a sole supplier of blood collection tubes, and Twist Bioscience Corporation as a sole supplier of DNA panels.”
SupplierTwist Biosciences“•We rely on Illumina, Inc. as a sole supplier for our next-generation sequencers and associated reagents, Madison Industries as a sole supplier of blood collection tubes, and Twist Bioscience Corporation as a sole supplier of DNA panels.”
PartnerSamsung Electronics“We have also begun entering select international markets through distributor partners, including Israel and Canada, and intend to enter South Korea through our partnership with Samsung.”
PartnerSamsung C&T“Also in October 2025, we announced subject to final execution of definitive agreements, that we will work with Samsung C&T as exclusive partners to commercialize the Galleri test in South Korea, with a possible extension into other Asian geographies, including Japan and Singapore.”
PartnerFord (F)“Collaborators include, among others, the Cleveland Clinic, Duke Health, Henry Ford Health System, Mayo Clinic, Oregon Health and Science University (OHSU), Memorial Care, Sutter Health, and the US Oncology Network.”

Quoted from the company's 10-K filed Mar 12, 2026.

Companies that name GRAL in their SEC reports

Relationship to GRALCompanyFilingSentence
supplierILLUMINA, INC. (ILMN)10-K Feb 12, 2026“Revenue from genotyping and sequencing services, including cancer detection testing services related to the GRAIL business prior to the Spin-Off, is recognized when earned, which is generally at the time the genotyping or sequencing analysis data is made available to the customer.”

GRAL customer concentration

In the period ended Jun 30, 2026, a single direct customer accounted for 10% of revenue, per the company's 10-Q filed Aug 6, 2026. The company does not name it.

GRAL analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-1.90$-2.38+$0.48$44.2M4
Next quarter (ends Dec 2026)$-2.09$-2.45+$0.36$51.2M5
Current fiscal year (ends Dec 2026)$-7.52$-9.14+$1.63$180.8M5
Next fiscal year (ends Dec 2027)$-8.25$-9.72+$1.47$227.2M4

GRAL options: expected move

Options price a move of about ±19.3% (±$30.40) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±11.8% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262297.0%±19.3%
Dec 18, 20265084.8%±25.1%
Jan 15, 20277881.8%±29.9%
Apr 16, 202716981.0%±43.1%

30-day implied volatility 93.2% vs 120.1% realized over the last 30 trading days. Put/call ratio (volume) 0.22. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 17:22 UTC)

PriceUSD 159.72
Change▲ 1.16% (up)
Previous CloseUSD 157.88
OpenUSD 156.27
Day RangeUSD 155.69 – 161.9
52-Week RangeUSD 41.5 – 166.48
Volume285,252 shares
Market Cap$7.13B
ExchangeNMS

Technical Analysis (GRAL)

Nexqual's technical model rates GRAL "BUY" based on 5 bullish and 2 bearish signals across 128 daily candles, as of October 29, 2026 at 17:22 UTC.

Overall SignalBUY
RSI (14)71.63 (overbought)
vs SMA50Above (USD 110.7)
MACD10.16 (positive)

Analyst Ratings (GRAL)

Wall Street analysts rate GRAL "Hold" based on 10 analysts, with a mean price target of USD 132.56 (range USD 74–180), per Nexqual as of October 29, 2026 at 17:22 UTC.

Consensus RatingHold
Analyst Count10
Mean TargetUSD 132.56
High TargetUSD 180
Low TargetUSD 74
Buy / Hold / Sell5 / 5 / 0

Earnings (GRAL)

Next Earnings Date2026-11-04
EPS EstimateUSD -1.9
Revenue Estimate$44.21M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -1.34 vs est -2.43 ▲ beat
2026-03-31USD -1.37 vs est -1.96 ▲ beat
2025-12-31USD -2.44 vs est -2.53 ▲ beat
2025-09-30USD -2.46 vs est -3.27 ▲ beat

Source: Nexqual, October 29, 2026 at 17:22 UTC.

Financials & Fundamentals (GRAL)

Total Revenue$165.26M
Revenue Growth (latest quarter, YoY)+25.70%
Gross Margin+49.71%
Operating Margin-332.00%
Profit Margin-236.95%
ROE-16.12%
Debt / Equity0.04
Current Ratio10.95
Total Cash$861.61M
Total Debt$91.31M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$296.16M (-179.2% of revenue)

Source: Nexqual, October 29, 2026 at 17:22 UTC.

Financial Health Score (GRAL)

Nexqual rates GRAIL, Inc.'s overall financial health "Mixed" across five dimensions, as of October 29, 2026 at 17:22 UTC.

GrowthStrong — Revenue +17% YoY (annual)
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $862M cash vs $91M debt, net cash position
Cash FlowWeak — FCF negative: -$296M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -15%, ROA -13.8% (last 4 quarters, SEC)

Ownership (GRAL)

Insider Ownership+4.79%
Institutional Ownership+86.79%
Shares Outstanding44.67M
Float34.34M
Short % of Float+18.60%

Source: Nexqual, October 29, 2026 at 17:22 UTC.

Leadership (GRAL)

GRAIL, Inc. is led by Joshua J. Ofman M.D., M.S.H.S, CEO & Director, per Nexqual as of October 29, 2026 at 17:22 UTC.

CEO & DirectorJoshua J. Ofman M.D., M.S.H.S
CFO & Head of Corporate DevelopmentAaron Freidin
Senior Vice President of Global Development & OperationsPaul Ciccolella
Chief Technology OfficerSatnam Alag
Chief Scientific Officer and President of Global Clinical & Medical AffairsHarpal S. Kumar M.A., M.B.A., MEng

Major Backers & Investors (GRAL)

Notable institutional backers of GRAIL, Inc. include Farallon Capital Management LLC, Baker Bros. Advisors, LP, Primecap Management Company, according to Nexqual as of October 29, 2026 at 17:22 UTC.

Active Investors

InvestorStake
Farallon Capital Management LLC9.32%
Baker Bros. Advisors, LP9.02%
Primecap Management Company4.88%
Sessa Capital IM, L.P.4.56%
Deep Track Capital, Lp4.11%
PRIMECAP Odyssey Funds-PRIMECAP Odyssey Aggressive Growth Fund3.54%
Morgan Stanley3.27%

Index Funds (Passive)

FundStake
BlackRock8.01%
State Street5.34%
Vanguard Group3.67%

Source: Nexqual, October 29, 2026 at 17:22 UTC.

From GRAIL, Inc.'s Latest SEC 10-K Filing (filed 2026-03-12)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 17:22 UTC. This page is informational and not investment advice.

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