GRAIL, Inc. (GRAL) Stock Price & Analysis
GRAIL, Inc. (GRAL) is trading at USD 159.72, up 1.16% today, as of October 29, 2026 at 17:21 UTC (US market open; quotes may be delayed), according to Nexqual market data.
GRAL last closed at USD 157.88; today's session has ranged USD 155.69–161.9 on volume of 285,252 shares. Market capitalization is $7.13B, with a 52-week range of USD 41.5–166.48 (NMS). Source: Nexqual, retrieved October 29, 2026 at 17:22 UTC.
Also available as compact Markdown for AI agents: nexqual.com/GRAL.md
Key facts (GRAL)
- Last four reported quarters (through Jun 30, 2026): revenue $165M, net income -$392M (-236.9% margin), free cash flow -$296M (SEC filings).
- Insider open-market sales, last ~7 months: 8 Form 4 filings, $14.9M; 3 not under a Rule 10b5-1 plan ($4.7M); 0 by opportunistic insiders, 0 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Hold (mean 2.50 on a 1–5 scale) (10 analysts), mean target USD 132.56 (range 74–180).
- Total return with dividends: 1Y +87.4% vs S&P 500 +13.0%; 5Y +992.4% vs S&P 500 +78.9%.
- Next earnings: 2026-11-04, EPS estimate USD -1.9, revenue estimate $44.2M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (GRAL)
| USD | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|
| Revenue | $55.5M | $93.1M | $126M | $147M | $165M |
| Operating income | -$5.44B | -$1.52B | -$2.19B | -$562M | -$559M |
| Net income | -$5.40B | -$1.47B | -$2.03B | -$408M | -$392M |
| EPS (diluted) | -$173.89 | -$47.21 | -$63.54 | -$11.11 | — |
| Free cash flow | -$584M | -$609M | -$582M | -$300M | -$296M |
| Operating margin | -9798.2% | -1627.6% | -1743.0% | -382.0% | -338.4% |
| Net margin | -9719.3% | -1574.2% | -1613.9% | -277.5% | -236.9% |
| Revenue growth | — | +67.6% | +34.9% | +17.2% | — |
| Cash + short-term investments | $242M | $97.3M | $761M | $902M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (GRAL)
P/S 43.2x · P/B 2.8x · FCF yield -4.15% · Earnings yield -5.49%
Insider sales (SEC Form 4, open-market, last ~7 months) (GRAL)
5 of 8 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-10-15 | Ofman Joshua J. | Chief Executive Officer | 20,000 | $2.7M | 5.5% | Yes (adopted December 2, 2025) | Too little history (no open-market trades in 2023) |
| 2026-10-05 | Partridge Andrew John | Chief Growth Officer | 7,873 | $1.2M | 4.8% | No | Too little history (no open-market trades in 2023–2025) |
| 2026-10-05 | Freidin Aaron | Chief Financial Officer | 23,619 | $3.5M | 9.5% | No | Too little history (no open-market trades in 2023) |
| 2026-09-21 | Freidin Aaron | Chief Financial Officer | 4,100 | $383K | 1.6% | Yes (adopted December 11, 2025) | Too little history (no open-market trades in 2023) |
| 2026-09-21 | Ofman Joshua J. | Chief Executive Officer | 61,452 | $6.0M | 14.5% | Yes (adopted December 2, 2025) | Too little history (no open-market trades in 2023) |
| 2026-08-27 | Ofman Joshua J. | Chief Executive Officer | 5,000 | $425K | 1.2% | Yes | Too little history (no open-market trades in 2023) |
| 2026-08-27 | Freidin Aaron | Chief Financial Officer | 7,900 | $672K | 3% | Yes | Too little history (no open-market trades in 2023) |
| 2026-06-04 | Partridge Andrew John | Chief Growth Officer | 1,491 | $91K | 0.9% | No | Too little history (no open-market trades in 2023–2025) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (GRAL)
Consensus Hold (mean 2.50 on a 1–5 scale), 10 analysts; mean target USD 132.56 (low 74, high 180).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-13 | Morgan Stanley | Target raised | Equal-Weight | $60 → $120 |
| 2026-10-13 | TD Cowen | Target raised | Buy | $88 → $180 |
| 2026-10-02 | UBS | Target raised | Buy | $105 → $175 |
| 2026-10-01 | Guggenheim | Target raised | Buy | $75 → $155 |
| 2026-09-28 | Canaccord Genuity | Target raised | Buy | $80 → $150 |
| 2026-09-25 | Mizuho | Target raised | Neutral | $65 → $100 |
| 2026-09-22 | Baird | Target raised | Outperform | $96 → $118 |
| 2026-09-17 | RBC Capital | Initiated | Sector Perform | $84 |
| 2026-09-09 | UBS | Initiated | Buy | $105 |
| 2026-07-15 | Mizuho | Target raised | Neutral | $58 → $65 |
Total return (dividends reinvested) (GRAL)
| 1Y (from 2025-10-29) | 5Y (from 2024-06-10) | |
|---|---|---|
| Total return | +87.4% | +992.4% |
| S&P 500 (SPY) | +13.0% | +78.9% |
| Per year | +87.5% | +172.4% |
| Volatility (annualized) | 111.0% | 101.4% |
| Max drawdown | -62.9% (Jan 2026→Feb 2026) | -61.0% (Nov 2025→Mar 2026) |
GRAL earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 5, 2026 | Quarter ended Jun 30, 2026 | −$1.34 | −$2.43 | Beat +44.9% | -12.8% |
| May 5, 2026 | Quarter ended Mar 31, 2026 | −$1.37 | −$1.96 | Beat +30.1% | +12.7% |
| Feb 19, 2026 | Quarter ended Dec 31, 2025 | −$2.44 | −$2.53 | Beat +3.6% | -50.9% |
| Jan 12, 2026 | Quarter ended Dec 31, 2025 | −$2.44 | −$2.53 | Beat +3.6% | +1.9% |
| Nov 12, 2025 | Quarter ended Sep 30, 2025 | −$2.46 | −$3.26 | Beat +24.5% | -0.2% |
| Oct 16, 2025 | Quarter ended Sep 30, 2025 | −$2.46 | −$3.26 | Beat +24.5% | +3.3% |
| Aug 12, 2025 | — | — | — | — | +3.9% |
| May 13, 2025 | — | — | — | — | -8.6% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
GRAL recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Aug 13, 2026 | Schedule 13G/A | Farallon Capital Management, L.L.C., Farallon Capital Partners, L.P.: 9.6% of shares, passive 5%+ holder (amended) |
| Aug 7, 2026 | Schedule 13G | STATE STREET CORPORATION: 5.6% of shares, passive 5%+ holder |
| Aug 6, 2026 | Schedule 13G/A | PRIMECAP MANAGEMENT CO/CA/: 5.1% of shares, passive 5%+ holder (amended) |
| Aug 6, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 5, 2026 | 8-K | Quarterly results |
| Jul 28, 2026 | Schedule 13G/A | BlackRock, Inc.: 7.9% of shares, passive 5%+ holder (amended) |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
GRAL revenue by product line (quarter ended Jun 30, 2026)
| Line | Revenue | Share of total | YoY |
|---|---|---|---|
| Screening revenue | $42.6M | 95.4% | +24.0% |
| Development Services | $2.0M | 4.6% | +75.5% |
| Total revenue | $44.7M | 100% | — |
As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).
GRAL suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Supplier | ILLUMINA, INC. (ILMN) | “•We rely on Illumina, Inc. as a sole supplier for our next-generation sequencers and associated reagents, Madison Industries as a sole supplier of blood collection tubes, and Twist Bioscience Corporation as a sole supplier of DNA panels.” |
| Supplier | Twist Biosciences | “•We rely on Illumina, Inc. as a sole supplier for our next-generation sequencers and associated reagents, Madison Industries as a sole supplier of blood collection tubes, and Twist Bioscience Corporation as a sole supplier of DNA panels.” |
| Partner | Samsung Electronics | “We have also begun entering select international markets through distributor partners, including Israel and Canada, and intend to enter South Korea through our partnership with Samsung.” |
| Partner | Samsung C&T | “Also in October 2025, we announced subject to final execution of definitive agreements, that we will work with Samsung C&T as exclusive partners to commercialize the Galleri test in South Korea, with a possible extension into other Asian geographies, including Japan and Singapore.” |
| Partner | Ford (F) | “Collaborators include, among others, the Cleveland Clinic, Duke Health, Henry Ford Health System, Mayo Clinic, Oregon Health and Science University (OHSU), Memorial Care, Sutter Health, and the US Oncology Network.” |
Quoted from the company's 10-K filed Mar 12, 2026.
Companies that name GRAL in their SEC reports
| Relationship to GRAL | Company | Filing | Sentence |
|---|---|---|---|
| supplier | ILLUMINA, INC. (ILMN) | 10-K Feb 12, 2026 | “Revenue from genotyping and sequencing services, including cancer detection testing services related to the GRAIL business prior to the Spin-Off, is recognized when earned, which is generally at the time the genotyping or sequencing analysis data is made available to the customer.” |
GRAL customer concentration
In the period ended Jun 30, 2026, a single direct customer accounted for 10% of revenue, per the company's 10-Q filed Aug 6, 2026. The company does not name it.
GRAL analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-1.90 | $-2.38 | +$0.48 | $44.2M | 4 |
| Next quarter (ends Dec 2026) | $-2.09 | $-2.45 | +$0.36 | $51.2M | 5 |
| Current fiscal year (ends Dec 2026) | $-7.52 | $-9.14 | +$1.63 | $180.8M | 5 |
| Next fiscal year (ends Dec 2027) | $-8.25 | $-9.72 | +$1.47 | $227.2M | 4 |
GRAL options: expected move
Options price a move of about ±19.3% (±$30.40) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±11.8% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 22 | 97.0% | ±19.3% |
| Dec 18, 2026 | 50 | 84.8% | ±25.1% |
| Jan 15, 2027 | 78 | 81.8% | ±29.9% |
| Apr 16, 2027 | 169 | 81.0% | ±43.1% |
30-day implied volatility 93.2% vs 120.1% realized over the last 30 trading days. Put/call ratio (volume) 0.22. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 29, 2026 at 17:22 UTC)
| Price | USD 159.72 |
|---|---|
| Change | ▲ 1.16% (up) |
| Previous Close | USD 157.88 |
| Open | USD 156.27 |
| Day Range | USD 155.69 – 161.9 |
| 52-Week Range | USD 41.5 – 166.48 |
| Volume | 285,252 shares |
| Market Cap | $7.13B |
| Exchange | NMS |
Technical Analysis (GRAL)
Nexqual's technical model rates GRAL "BUY" based on 5 bullish and 2 bearish signals across 128 daily candles, as of October 29, 2026 at 17:22 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 71.63 (overbought) |
| vs SMA50 | Above (USD 110.7) |
| MACD | 10.16 (positive) |
Analyst Ratings (GRAL)
Wall Street analysts rate GRAL "Hold" based on 10 analysts, with a mean price target of USD 132.56 (range USD 74–180), per Nexqual as of October 29, 2026 at 17:22 UTC.
| Consensus Rating | Hold |
|---|---|
| Analyst Count | 10 |
| Mean Target | USD 132.56 |
| High Target | USD 180 |
| Low Target | USD 74 |
| Buy / Hold / Sell | 5 / 5 / 0 |
Earnings (GRAL)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD -1.9 |
| Revenue Estimate | $44.21M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -1.34 vs est -2.43 ▲ beat |
| 2026-03-31 | USD -1.37 vs est -1.96 ▲ beat |
| 2025-12-31 | USD -2.44 vs est -2.53 ▲ beat |
| 2025-09-30 | USD -2.46 vs est -3.27 ▲ beat |
Source: Nexqual, October 29, 2026 at 17:22 UTC.
Financials & Fundamentals (GRAL)
| Total Revenue | $165.26M |
|---|---|
| Revenue Growth (latest quarter, YoY) | +25.70% |
| Gross Margin | +49.71% |
| Operating Margin | -332.00% |
| Profit Margin | -236.95% |
| ROE | -16.12% |
| Debt / Equity | 0.04 |
| Current Ratio | 10.95 |
| Total Cash | $861.61M |
| Total Debt | $91.31M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$296.16M (-179.2% of revenue) |
Source: Nexqual, October 29, 2026 at 17:22 UTC.
Financial Health Score (GRAL)
Nexqual rates GRAIL, Inc.'s overall financial health "Mixed" across five dimensions, as of October 29, 2026 at 17:22 UTC.
| Growth | Strong — Revenue +17% YoY (annual) |
|---|---|
| Profitability | Critical — Heavily loss-making — early-stage company |
| Balance Sheet | Strong — $862M cash vs $91M debt, net cash position |
| Cash Flow | Weak — FCF negative: -$296M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE -15%, ROA -13.8% (last 4 quarters, SEC) |
Ownership (GRAL)
| Insider Ownership | +4.79% |
|---|---|
| Institutional Ownership | +86.79% |
| Shares Outstanding | 44.67M |
| Float | 34.34M |
| Short % of Float | +18.60% |
Source: Nexqual, October 29, 2026 at 17:22 UTC.
Leadership (GRAL)
GRAIL, Inc. is led by Joshua J. Ofman M.D., M.S.H.S, CEO & Director, per Nexqual as of October 29, 2026 at 17:22 UTC.
| CEO & Director | Joshua J. Ofman M.D., M.S.H.S |
|---|---|
| CFO & Head of Corporate Development | Aaron Freidin |
| Senior Vice President of Global Development & Operations | Paul Ciccolella |
| Chief Technology Officer | Satnam Alag |
| Chief Scientific Officer and President of Global Clinical & Medical Affairs | Harpal S. Kumar M.A., M.B.A., MEng |
Major Backers & Investors (GRAL)
Notable institutional backers of GRAIL, Inc. include Farallon Capital Management LLC, Baker Bros. Advisors, LP, Primecap Management Company, according to Nexqual as of October 29, 2026 at 17:22 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Farallon Capital Management LLC | 9.32% |
| Baker Bros. Advisors, LP | 9.02% |
| Primecap Management Company | 4.88% |
| Sessa Capital IM, L.P. | 4.56% |
| Deep Track Capital, Lp | 4.11% |
| PRIMECAP Odyssey Funds-PRIMECAP Odyssey Aggressive Growth Fund | 3.54% |
| Morgan Stanley | 3.27% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 8.01% |
| State Street | 5.34% |
| Vanguard Group | 3.67% |
Source: Nexqual, October 29, 2026 at 17:22 UTC.
From GRAIL, Inc.'s Latest SEC 10-K Filing (filed 2026-03-12)
Key Strengths & Strategy (as disclosed to the SEC)
- The law included certain standards, including that Centers for Medicare and Medicaid Services ("CMS") would establish coverage through a national coverage determination ("NCD") process under "reasonable and necessary" evidentiary requirements.
- We can leverage our proprietary platform for additional applications, including our precision oncology portfolio.
- The commercial opportunity for Galleri is significant, with more than 300 million individuals globally over the age of 50 (our intended use population), including more than 100 million individuals in the United States.
- Our proprietary targeted methylation platform, as well as our growing body of clinical and real-world data, have provided us with unique insights into cancer biology that enable development of products beyond asymptomatic screening.
Partnerships
- We have also begun entering select international markets through distributor partners, including Israel and Canada, and intend to enter South Korea through our partnership with Samsung.
- Under our agreement with the NHS, these results have met certain success criteria and missed others.
Legal & Regulatory Risks (Item 1A, quoted)
- The PMA approval process can be expensive, lengthy and uncertain.
- The global data protection landscape is rapidly evolving and we and our partners are or may be subject to federal, state, and foreign data protection laws and regulations (i.e., laws and regulations that address data privacy and security).
- We receive, store, process and disclose personal information as part of our business and as our operations and business grow, we may become subject to or affected by new or additional data protection laws and regulations and face increased scrutiny or attention from regulatory authorities.
- Our business may be affected by the evolving regulatory framework for AI Technologies.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| RDNT | RadNet, Inc. | USD 74.37 | ▲ 1.13% |
| BLLN | BillionToOne, Inc. | USD 114.54 | ▲ 0.47% |
| SHC | Sotera Health Company | USD 18.68 | ▲ 0.16% |
| QGEN | Qiagen N.V. | USD 50.35 | ▲ 0.04% |
| ADPT | Adaptive Biotechnologies Corpor | USD 28.22 | ▼ 0.55% |
| VCYT | Veracyte, Inc. | USD 51.37 | ▲ 2.11% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 17:22 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt