Ironwood Pharmaceuticals, Inc. (IRWD) Stock Price & Analysis
Ironwood Pharmaceuticals, Inc. (IRWD) closed at USD 3.61 on Wednesday, October 28, 2026, up 2.85% on the day. The US market is currently closed; this is not a live price.
The prior close was USD 3.51; the Oct 28, 2026 session ranged USD 3.46–3.63 on volume of 1,411,305 shares. Market capitalization is $596.52M, with a 52-week range of USD 1.47–5.78 (NMS). Source: Nexqual, retrieved October 29, 2026 at 07:41 UTC.
Also available as compact Markdown for AI agents: nexqual.com/IRWD.md
Key facts (IRWD)
- Last four reported quarters (through Jun 30, 2026): revenue $389M, net income $130M (33.4% margin) (SEC filings).
- Valuation: P/E 4.6x (avg 414.4x at the last 2 fiscal year-ends).
- Insider open-market sales, last ~7 months: 2 Form 4 filings, $659K; 0 not under a Rule 10b5-1 plan ($0K); 0 by opportunistic insiders, 1 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.25 on a 1–5 scale) (4 analysts), mean target USD 6.1 (range 3.7–10).
- Total return with dividends: 1Y +139.1% vs S&P 500 +13.6%; 5Y -71.7% vs S&P 500 +79.8%.
- Next earnings: 2026-11-05, EPS estimate USD 0.31, revenue estimate $122M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (IRWD)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $414M | $411M | $443M | $351M | $296M | $389M |
| Operating income | $232M | $250M | -$945M | $93.1M | $98.5M | $234M |
| Net income | $528M | $175M | -$1.00B | $880K | $24.0M | $130M |
| EPS (diluted) | $3.21 | $0.96 | -$6.45 | $0.01 | $0.15 | — |
| Free cash flow | $262M | $274M | $183M | $103M | $127M | — |
| Operating margin | 56.1% | 61.0% | -213.5% | 26.5% | 33.3% | 60.1% |
| Net margin | 127.7% | 42.6% | -226.4% | 0.3% | 8.1% | 33.4% |
| Revenue growth | +6.2% | -0.8% | +7.8% | -20.6% | -15.7% | — |
| Cash + short-term investments | $620M | $656M | $92.2M | $88.6M | $215M | — |
| Total debt | $454M | $396M | $398M | $199M | — | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (IRWD)
P/E 4.6x · P/S 1.5x · Earnings yield 21.77%
P/E at fiscal year-ends: Dec 2025 22.9x, Dec 2024 805.9x.
Insider sales (SEC Form 4, open-market, last ~7 months) (IRWD)
2 of 2 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-07-07 | Silver Ronald | PFO & PAO | 127,890 | $578K | 29% | Yes | Routine (sold in Feb & Aug each year 2023–2025; this trade is outside those months) |
| 2026-06-16 | McHugh Julie | Director | 21,571 | $80K | 7.9% | Yes | Too little history (no open-market trades in 2023 or 2025) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (IRWD)
Consensus Buy (mean 2.25 on a 1–5 scale), 4 analysts; mean target USD 6.1 (low 3.7, high 10).
Total return (dividends reinvested) (IRWD)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +139.1% | -71.7% |
| S&P 500 (SPY) | +13.6% | +79.8% |
| Per year | +139.8% | -22.3% |
| Volatility (annualized) | 86.8% | 71.5% |
| Max drawdown | -43.6% (Jan 2026→Mar 2026) | -96.3% (Feb 2024→May 2025) |
IRWD earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 6, 2026 | Quarter ended Jun 30, 2026 | $0.31 | $0.28 | Beat +10.7% | +4.1% |
| May 7, 2026 | Quarter ended Mar 31, 2026 | $0.24 | $0.24 | In line | -12.6% |
| Feb 25, 2026 | Quarter ended Dec 31, 2025 | −$0.01 | $0.01 | Miss −$0.02 | -3.4% |
| Jan 2, 2026 | Quarter ended Sep 30, 2025 | $0.24 | $0.12 | Beat +100.0% | +36.2% |
| Nov 10, 2025 | Quarter ended Sep 30, 2025 | $0.24 | $0.12 | Beat +100.0% | +50.5% |
| Aug 7, 2025 | — | — | — | — | +11.1% |
| May 7, 2025 | — | — | — | — | -24.7% |
| Apr 25, 2025 | — | — | — | — | +10.2% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
IRWD recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Oct 28, 2026 | Schedule 13G/A | BANK OF AMERICA CORP /DE/: 3.2% of shares, passive 5%+ holder (amended) |
| Oct 16, 2026 | 8-K | Director or executive officer change, or pay arrangement “Ironwood Pharmaceuticals, Inc. (the "Company") today announced that, on October 12, 2026, the Board of Directors (the "Board") appointed Tammi Gaskins, the Company's Senior Vice President, Chief Commercial Officer, as Chief Executive Officer, effective January 1, 2027 (the "Transition Date"). The Board increased the size of the Board from eight to nine directors and elected Ms. Gaskins as a director, in each case, effective as of the Transition Date. Biographical information for Ms. Gaskins is available on page 22…” |
| Aug 14, 2026 | Schedule 13G/A | Armistice Capital, LLC, Steven Boyd: 8.4% of shares, passive 5%+ holder (amended) |
| Aug 7, 2026 | Schedule 13G | STATE STREET CORPORATION: 5.4% of shares, passive 5%+ holder |
| Aug 6, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 6, 2026 | 8-K | Quarterly results |
| Jul 28, 2026 | Schedule 13G/A | BlackRock, Inc.: 8.1% of shares, passive 5%+ holder (amended) |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
IRWD suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | AbbVie (ABBV) | “We have strategic partnerships with leading pharmaceutical companies to support the development and commercialization of linaclotide throughout the world, including with our partner, AbbVie Inc. (together with its affiliates), or AbbVie, in the U.S. and all countries worldwide other than China (including Hong Kong and Macau) and Japan, AstraZeneca AB (together with its affiliates), or AstraZeneca, in China (includ…” |
| Partner | Astellas Pharma | “In November 2009, we entered into a license agreement with Astellas to develop and commercialize linaclotide for the treatment of IBS-C, CIC, and other GI conditions in Japan.” |
| Partner | COUR Pharmaceutical Development Company | “Through a collaboration and license option agreement, or the COUR Collaboration Agreement, we and COUR Pharmaceutical Development Company, Inc., or COUR, were developing CNP-104 for the treatment of PBC, a rare autoimmune disease targeting the liver.” |
| Partner | Almirall | “In April 2009, we entered into a license agreement with Almirall, S.A., or Almirall, or the European License Agreement, to develop and commercialize linaclotide in Europe (including the Commonwealth of Independent States and Turkey) for the treatment of IBS-C, CIC, and other GI conditions.” |
| Partner | Asahi Kasei Pharma | “We continue to plan for a potential commercial launch of apraglutide, if successfully developed and approved, in the U.S. and with partners in territories outside the U.S. For example, we granted AKP an exclusive license to sublicense, develop, commercialize and exploit products derived from apraglutide in Japan.” |
| Partner | GlyPharma Therapeutic | “For example, we are a party to an amended and restated exclusive license agreement, dated as of December 6, 2016, as amended, by and between GlyPharma Therapeutic Inc. (as predecessor to VectivBio AG) and Ferring, or the Ferring Agreement, pursuant to which we have exclusive rights to apraglutide including an issued composition of matter and method of use patent in the U.S. in lead indications.” |
| Partner | VectivBio Holding | “For example, we are a party to an amended and restated exclusive license agreement, dated as of December 6, 2016, as amended, by and between GlyPharma Therapeutic Inc. (as predecessor to VectivBio AG) and Ferring, or the Ferring Agreement, pursuant to which we have exclusive rights to apraglutide including an issued composition of matter and method of use patent in the U.S. in lead indications.” |
| Partner | Ferring International Center | “For example, we are a party to an amended and restated exclusive license agreement, dated as of December 6, 2016, as amended, by and between GlyPharma Therapeutic Inc. (as predecessor to VectivBio AG) and Ferring, or the Ferring Agreement, pursuant to which we have exclusive rights to apraglutide including an issued composition of matter and method of use patent in the U.S. in lead indications.” |
Quoted from the company's 10-K filed Feb 26, 2026.
Companies that name IRWD in their SEC reports
| Relationship to IRWD | Company | Filing | Sentence |
|---|---|---|---|
| partner | Neuphoria Therapeutics Inc. (NEUP) | 10-K Sep 18, 2026 | “Research and License Agreement with Ironwood Pharmaceuticals” |
| partner | Korsana Biosciences, Inc. (KRSA) | 10-K Mar 30, 2026 | “Our employee, consultants, non-academic outside scientific collaborators and other advisors enter into confidentiality and intellectual property assignment agreements with us or have entered into confidentiality and intellectual property assignment agreements with Ironwood or third parties licensing intellectual property to us.” |
IRWD company outlook (results filed Aug 6, 2026)
- “(linaclotide) U.S. net sales guidance to $1.15 - $1.20 billion, representing greater than 30% increase year-over-year;”
Analysts expect $121.6M for the current quarter, 89.7% below the midpoint of the company's guidance ($1.18B).
Quoted word-for-word from the SEC 8-K results press release.
IRWD analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $0.31 | $0.29 | +6.9% | $121.6M | 2 |
| Next quarter (ends Dec 2026) | $0.34 | $0.28 | +19.3% | $128.3M | 2 |
| Current fiscal year (ends Dec 2026) | $1.21 | $1.09 | +11.0% | $471.4M | 2 |
| Next fiscal year (ends Dec 2027) | $1.50 | $1.44 | +4.2% | $494.1M | 3 |
IRWD options: expected move
Options price a move of about ±31.6% (±$1.15) by Nov 20, 2026, which includes earnings on Nov 5, 2026. Over the last 8 reports the stock moved ±19.1% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 23 | 232.2% | ±31.6% |
| Feb 19, 2027 | 114 | 104.6% | ±38.5% |
30-day implied volatility 67.4% vs 48.5% realized over the last 30 trading days. Put/call ratio (volume) 0. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 29, 2026 at 07:41 UTC)
| Price | USD 3.61 |
|---|---|
| Change | ▲ 2.85% (up) |
| Previous Close | USD 3.51 |
| Open | USD 3.46 |
| Day Range | USD 3.46 – 3.63 |
| 52-Week Range | USD 1.47 – 5.78 |
| Volume | 1,411,305 shares |
| Market Cap | $596.52M |
| Exchange | NMS |
Technical Analysis (IRWD)
Nexqual's technical model rates IRWD "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 29, 2026 at 07:41 UTC.
| Overall Signal | STRONG SELL |
|---|---|
| RSI (14) | 45.5 (neutral) |
| vs SMA50 | Below (USD 3.98) |
| MACD | -0.13 (negative) |
Analyst Ratings (IRWD)
Wall Street analysts rate IRWD "Buy" based on 4 analysts, with a mean price target of USD 6.1 (range USD 3.7–10), per Nexqual as of October 29, 2026 at 07:41 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 4 |
| Mean Target | USD 6.1 |
| High Target | USD 10 |
| Low Target | USD 3.7 |
| Buy / Hold / Sell | 2 / 2 / 0 |
Earnings (IRWD)
| Next Earnings Date | 2026-11-05 |
|---|---|
| EPS Estimate | USD 0.31 |
| Revenue Estimate | $121.57M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD 0.31 vs est 0.28 ▲ beat |
| 2026-03-31 | USD 0.24 vs est 0.24 ▲ beat |
| 2025-12-31 | USD -0.01 vs est 0.01 ▼ miss |
| 2025-09-30 | USD 0.24 vs est 0.12 ▲ beat |
Source: Nexqual, October 29, 2026 at 07:41 UTC.
Financials & Fundamentals (IRWD)
| Total Revenue | $389.32M |
|---|---|
| Revenue Growth (latest quarter, YoY) | +32.60% |
| Gross Margin | +77.22% |
| Operating Margin | +70.16% |
| Profit Margin | +33.36% |
| Current Ratio | 6.06 |
| Total Cash | $79.13M |
| Total Debt | $396.87M |
| Free Cash Flow (fiscal year ended Dec 2025, SEC 10-K) | $127.01M (42.9% of revenue) |
Source: Nexqual, October 29, 2026 at 07:41 UTC.
Financial Health Score (IRWD)
Nexqual rates Ironwood Pharmaceuticals, Inc.'s overall financial health "Solid" across five dimensions, as of October 29, 2026 at 07:41 UTC.
| Growth | Critical — Revenue -16% YoY (annual), sharp decline |
|---|---|
| Profitability | Strong — Gross margin 77%, operating 60% (last 12 months) |
| Balance Sheet | Mixed — $140M cash and investments vs $200M debt (Sep 2025, SEC) |
| Cash Flow | Strong — FCF $127M (FY ended Dec 2025, 10-K), 43% margin |
| Efficiency | Strong — ROE not meaningful (negative equity); ROA 45.5% (last 4 quarters, SEC) |
Ownership (IRWD)
| Insider Ownership | +3.24% |
|---|---|
| Institutional Ownership | +98.93% |
| Shares Outstanding | 165.24M |
| Float | 136.76M |
| Short % of Float | +10.50% |
Source: Nexqual, October 29, 2026 at 07:41 UTC.
Leadership (IRWD)
Ironwood Pharmaceuticals, Inc. is led by Thomas A. McCourt, CEO & Director, per Nexqual as of October 29, 2026 at 07:41 UTC.
| CEO & Director | Thomas A. McCourt |
|---|---|
| Senior VP, Interim CFO, Corporate Controller & Chief Accounting Officer | Ronald Silver |
| Chief Strategy Officer | Jeff Ruberti |
Major Backers & Investors (IRWD)
Notable institutional backers of Ironwood Pharmaceuticals, Inc. include Armistice Capital, LLC, Sarissa Capital Management, LP, Bank of America Corporation, according to Nexqual as of October 29, 2026 at 07:41 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Armistice Capital, LLC | 8.43% |
| Sarissa Capital Management, LP | 5.56% |
| Bank of America Corporation | 5.26% |
| Renaissance Technologies | 4.84% |
| AQR Capital Management, LLC | 3.91% |
| Acadian Asset Management. LLC | 3.54% |
| Fidelity | 1.08% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 10.77% |
| Vanguard Group | 7.34% |
| State Street | 5.33% |
Source: Nexqual, October 29, 2026 at 07:41 UTC.
From Ironwood Pharmaceuticals, Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)
Key Strengths & Strategy (as disclosed to the SEC)
- FDA regulations, drug-device combination products are subject to current GMP requirements applicable to both drugs and devices, including the Quality System Regulations applicable to medical devices.
- We actively seek to protect the proprietary technology that we consider important to our business, including pursuing patents that cover our products, compositions, and formulations, their methods of use and the processes for their manufacture, as well as any other relevant inventions and improvements that are commercially important to the development of our business.
Partnerships
- License Agreement with AbbVie (All countries other than the countries and territories of North America, China (including Hong Kong and Macau), and Japan) In April 2009, we entered into a license agreement with Almirall, S.A., or Almirall, or the European License Agreement, to develop and commercialize linaclotide in Europe (including the Commonwealth of Independent States and Turkey) for the treatment of IBS-C, CIC, and other GI conditions.
- In October 2012, we entered into a collaboration agreement with AstraZeneca to co-develop and co-commercialize linaclotide in China (including Hong Kong and Macau).
Legal & Regulatory Risks (Item 1A, quoted)
- We may be subject to privacy and security laws in the various jurisdictions, both inside and outside the U.S., in which we operate and/or obtain or store personally identifiable information, such as the E.U.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| SUPN | Supernus Pharmaceuticals, Inc. | USD 41.08 | ▲ 0.29% |
| BHC | Bausch Health Companies Inc. | USD 6.92 | ▲ 9.67% |
| AMLX | Amylyx Pharmaceuticals, Inc. | USD 28.07 | ▼ 0.81% |
| RGC | Regencell Bioscience Holdings L | USD 7.27 | ▼ 2.55% |
| LQDA | Liquidia Corporation | USD 45.72 | ▲ 0.62% |
| INDV | Indivior Pharmaceuticals, Inc. | USD 34.77 | ▲ 0.14% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 07:41 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt