Ironwood Pharmaceuticals, Inc. (IRWD) Stock Price & Analysis

Ironwood Pharmaceuticals, Inc. (IRWD) closed at USD 3.61 on Wednesday, October 28, 2026, up 2.85% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 3.51; the Oct 28, 2026 session ranged USD 3.46–3.63 on volume of 1,411,305 shares. Market capitalization is $596.52M, with a 52-week range of USD 1.47–5.78 (NMS). Source: Nexqual, retrieved October 29, 2026 at 07:41 UTC.

Also available as compact Markdown for AI agents: nexqual.com/IRWD.md

Key facts (IRWD)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (IRWD)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$414M$411M$443M$351M$296M$389M
Operating income$232M$250M-$945M$93.1M$98.5M$234M
Net income$528M$175M-$1.00B$880K$24.0M$130M
EPS (diluted)$3.21$0.96-$6.45$0.01$0.15—
Free cash flow$262M$274M$183M$103M$127M—
Operating margin56.1%61.0%-213.5%26.5%33.3%60.1%
Net margin127.7%42.6%-226.4%0.3%8.1%33.4%
Revenue growth+6.2%-0.8%+7.8%-20.6%-15.7%—
Cash + short-term investments$620M$656M$92.2M$88.6M$215M—
Total debt$454M$396M$398M$199M——

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (IRWD)

P/E 4.6x · P/S 1.5x · Earnings yield 21.77%

P/E at fiscal year-ends: Dec 2025 22.9x, Dec 2024 805.9x.

Insider sales (SEC Form 4, open-market, last ~7 months) (IRWD)

2 of 2 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-07-07Silver RonaldPFO & PAO127,890$578K29%YesRoutine (sold in Feb & Aug each year 2023–2025; this trade is outside those months)
2026-06-16McHugh JulieDirector21,571$80K7.9%YesToo little history (no open-market trades in 2023 or 2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (IRWD)

Consensus Buy (mean 2.25 on a 1–5 scale), 4 analysts; mean target USD 6.1 (low 3.7, high 10).

Total return (dividends reinvested) (IRWD)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+139.1%-71.7%
S&P 500 (SPY)+13.6%+79.8%
Per year+139.8%-22.3%
Volatility (annualized)86.8%71.5%
Max drawdown-43.6% (Jan 2026→Mar 2026)-96.3% (Feb 2024→May 2025)

IRWD earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 6, 2026Quarter ended Jun 30, 2026$0.31$0.28Beat +10.7%+4.1%
May 7, 2026Quarter ended Mar 31, 2026$0.24$0.24In line-12.6%
Feb 25, 2026Quarter ended Dec 31, 2025−$0.01$0.01Miss −$0.02-3.4%
Jan 2, 2026Quarter ended Sep 30, 2025$0.24$0.12Beat +100.0%+36.2%
Nov 10, 2025Quarter ended Sep 30, 2025$0.24$0.12Beat +100.0%+50.5%
Aug 7, 2025————+11.1%
May 7, 2025————-24.7%
Apr 25, 2025————+10.2%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

IRWD recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 28, 2026Schedule 13G/ABANK OF AMERICA CORP /DE/: 3.2% of shares, passive 5%+ holder (amended)
Oct 16, 20268-KDirector or executive officer change, or pay arrangement
“Ironwood Pharmaceuticals, Inc. (the "Company") today announced that, on October 12, 2026, the Board of Directors (the "Board") appointed Tammi Gaskins, the Company's Senior Vice President, Chief Commercial Officer, as Chief Executive Officer, effective January 1, 2027 (the "Transition Date"). The Board increased the size of the Board from eight to nine directors and elected Ms. Gaskins as a director, in each case, effective as of the Transition Date. Biographical information for Ms. Gaskins is available on page 22…”
Aug 14, 2026Schedule 13G/AArmistice Capital, LLC, Steven Boyd: 8.4% of shares, passive 5%+ holder (amended)
Aug 7, 2026Schedule 13GSTATE STREET CORPORATION: 5.4% of shares, passive 5%+ holder
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 6, 20268-KQuarterly results
Jul 28, 2026Schedule 13G/ABlackRock, Inc.: 8.1% of shares, passive 5%+ holder (amended)

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

IRWD suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerAbbVie (ABBV)“We have strategic partnerships with leading pharmaceutical companies to support the development and commercialization of linaclotide throughout the world, including with our partner, AbbVie Inc. (together with its affiliates), or AbbVie, in the U.S. and all countries worldwide other than China (including Hong Kong and Macau) and Japan, AstraZeneca AB (together with its affiliates), or AstraZeneca, in China (includ…”
PartnerAstellas Pharma“In November 2009, we entered into a license agreement with Astellas to develop and commercialize linaclotide for the treatment of IBS-C, CIC, and other GI conditions in Japan.”
PartnerCOUR Pharmaceutical Development Company“Through a collaboration and license option agreement, or the COUR Collaboration Agreement, we and COUR Pharmaceutical Development Company, Inc., or COUR, were developing CNP-104 for the treatment of PBC, a rare autoimmune disease targeting the liver.”
PartnerAlmirall“In April 2009, we entered into a license agreement with Almirall, S.A., or Almirall, or the European License Agreement, to develop and commercialize linaclotide in Europe (including the Commonwealth of Independent States and Turkey) for the treatment of IBS-C, CIC, and other GI conditions.”
PartnerAsahi Kasei Pharma“We continue to plan for a potential commercial launch of apraglutide, if successfully developed and approved, in the U.S. and with partners in territories outside the U.S. For example, we granted AKP an exclusive license to sublicense, develop, commercialize and exploit products derived from apraglutide in Japan.”
PartnerGlyPharma Therapeutic“For example, we are a party to an amended and restated exclusive license agreement, dated as of December 6, 2016, as amended, by and between GlyPharma Therapeutic Inc. (as predecessor to VectivBio AG) and Ferring, or the Ferring Agreement, pursuant to which we have exclusive rights to apraglutide including an issued composition of matter and method of use patent in the U.S. in lead indications.”
PartnerVectivBio Holding“For example, we are a party to an amended and restated exclusive license agreement, dated as of December 6, 2016, as amended, by and between GlyPharma Therapeutic Inc. (as predecessor to VectivBio AG) and Ferring, or the Ferring Agreement, pursuant to which we have exclusive rights to apraglutide including an issued composition of matter and method of use patent in the U.S. in lead indications.”
PartnerFerring International Center“For example, we are a party to an amended and restated exclusive license agreement, dated as of December 6, 2016, as amended, by and between GlyPharma Therapeutic Inc. (as predecessor to VectivBio AG) and Ferring, or the Ferring Agreement, pursuant to which we have exclusive rights to apraglutide including an issued composition of matter and method of use patent in the U.S. in lead indications.”

Quoted from the company's 10-K filed Feb 26, 2026.

Companies that name IRWD in their SEC reports

Relationship to IRWDCompanyFilingSentence
partnerNeuphoria Therapeutics Inc. (NEUP)10-K Sep 18, 2026“Research and License Agreement with Ironwood Pharmaceuticals”
partnerKorsana Biosciences, Inc. (KRSA)10-K Mar 30, 2026“Our employee, consultants, non-academic outside scientific collaborators and other advisors enter into confidentiality and intellectual property assignment agreements with us or have entered into confidentiality and intellectual property assignment agreements with Ironwood or third parties licensing intellectual property to us.”

IRWD company outlook (results filed Aug 6, 2026)

Analysts expect $121.6M for the current quarter, 89.7% below the midpoint of the company's guidance ($1.18B).

Quoted word-for-word from the SEC 8-K results press release.

IRWD analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$0.31$0.29+6.9%$121.6M2
Next quarter (ends Dec 2026)$0.34$0.28+19.3%$128.3M2
Current fiscal year (ends Dec 2026)$1.21$1.09+11.0%$471.4M2
Next fiscal year (ends Dec 2027)$1.50$1.44+4.2%$494.1M3

IRWD options: expected move

Options price a move of about ±31.6% (±$1.15) by Nov 20, 2026, which includes earnings on Nov 5, 2026. Over the last 8 reports the stock moved ±19.1% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202623232.2%±31.6%
Feb 19, 2027114104.6%±38.5%

30-day implied volatility 67.4% vs 48.5% realized over the last 30 trading days. Put/call ratio (volume) 0. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 07:41 UTC)

PriceUSD 3.61
Change▲ 2.85% (up)
Previous CloseUSD 3.51
OpenUSD 3.46
Day RangeUSD 3.46 – 3.63
52-Week RangeUSD 1.47 – 5.78
Volume1,411,305 shares
Market Cap$596.52M
ExchangeNMS

Technical Analysis (IRWD)

Nexqual's technical model rates IRWD "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 29, 2026 at 07:41 UTC.

Overall SignalSTRONG SELL
RSI (14)45.5 (neutral)
vs SMA50Below (USD 3.98)
MACD-0.13 (negative)

Analyst Ratings (IRWD)

Wall Street analysts rate IRWD "Buy" based on 4 analysts, with a mean price target of USD 6.1 (range USD 3.7–10), per Nexqual as of October 29, 2026 at 07:41 UTC.

Consensus RatingBuy
Analyst Count4
Mean TargetUSD 6.1
High TargetUSD 10
Low TargetUSD 3.7
Buy / Hold / Sell2 / 2 / 0

Earnings (IRWD)

Next Earnings Date2026-11-05
EPS EstimateUSD 0.31
Revenue Estimate$121.57M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 0.31 vs est 0.28 ▲ beat
2026-03-31USD 0.24 vs est 0.24 ▲ beat
2025-12-31USD -0.01 vs est 0.01 ▼ miss
2025-09-30USD 0.24 vs est 0.12 ▲ beat

Source: Nexqual, October 29, 2026 at 07:41 UTC.

Financials & Fundamentals (IRWD)

Total Revenue$389.32M
Revenue Growth (latest quarter, YoY)+32.60%
Gross Margin+77.22%
Operating Margin+70.16%
Profit Margin+33.36%
Current Ratio6.06
Total Cash$79.13M
Total Debt$396.87M
Free Cash Flow (fiscal year ended Dec 2025, SEC 10-K)$127.01M (42.9% of revenue)

Source: Nexqual, October 29, 2026 at 07:41 UTC.

Financial Health Score (IRWD)

Nexqual rates Ironwood Pharmaceuticals, Inc.'s overall financial health "Solid" across five dimensions, as of October 29, 2026 at 07:41 UTC.

GrowthCritical — Revenue -16% YoY (annual), sharp decline
ProfitabilityStrong — Gross margin 77%, operating 60% (last 12 months)
Balance SheetMixed — $140M cash and investments vs $200M debt (Sep 2025, SEC)
Cash FlowStrong — FCF $127M (FY ended Dec 2025, 10-K), 43% margin
EfficiencyStrong — ROE not meaningful (negative equity); ROA 45.5% (last 4 quarters, SEC)

Ownership (IRWD)

Insider Ownership+3.24%
Institutional Ownership+98.93%
Shares Outstanding165.24M
Float136.76M
Short % of Float+10.50%

Source: Nexqual, October 29, 2026 at 07:41 UTC.

Leadership (IRWD)

Ironwood Pharmaceuticals, Inc. is led by Thomas A. McCourt, CEO & Director, per Nexqual as of October 29, 2026 at 07:41 UTC.

CEO & DirectorThomas A. McCourt
Senior VP, Interim CFO, Corporate Controller & Chief Accounting OfficerRonald Silver
Chief Strategy OfficerJeff Ruberti

Major Backers & Investors (IRWD)

Notable institutional backers of Ironwood Pharmaceuticals, Inc. include Armistice Capital, LLC, Sarissa Capital Management, LP, Bank of America Corporation, according to Nexqual as of October 29, 2026 at 07:41 UTC.

Active Investors

InvestorStake
Armistice Capital, LLC8.43%
Sarissa Capital Management, LP5.56%
Bank of America Corporation5.26%
Renaissance Technologies4.84%
AQR Capital Management, LLC3.91%
Acadian Asset Management. LLC3.54%
Fidelity1.08%

Index Funds (Passive)

FundStake
BlackRock10.77%
Vanguard Group7.34%
State Street5.33%

Source: Nexqual, October 29, 2026 at 07:41 UTC.

From Ironwood Pharmaceuticals, Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

SymbolNamePriceChange
SUPNSupernus Pharmaceuticals, Inc.USD 41.08▲ 0.29%
BHCBausch Health Companies Inc.USD 6.92▲ 9.67%
AMLXAmylyx Pharmaceuticals, Inc.USD 28.07▼ 0.81%
RGCRegencell Bioscience Holdings LUSD 7.27▼ 2.55%
LQDALiquidia CorporationUSD 45.72▲ 0.62%
INDVIndivior Pharmaceuticals, Inc.USD 34.77▲ 0.14%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 07:41 UTC. This page is informational and not investment advice.

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