LeonaBio, Inc. (LONA) Stock Price & Analysis

LeonaBio, Inc. (LONA) closed at USD 5.29 on Thursday, October 15, 2026, down 1.86% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 5.39; the Oct 15, 2026 session ranged USD 4.91–5.42 on volume of 35,246 shares. Market capitalization is $49.84M, with a 52-week range of USD 2.21–14.21 (NCM). Source: Nexqual, retrieved October 16, 2026 at 05:19 UTC.

Also available as compact Markdown for AI agents: nexqual.com/LONA.md

Key facts (LONA)

Analysts (LONA)

Consensus Buy (mean 1.50 on a 1–5 scale), 4 analysts; mean target USD 17.33 (low 15, high 20).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-19MizuhoTarget loweredOutperform$16 → $15
2026-08-17CitizensTarget loweredMarket Outperform$18 → $17
2026-07-30CitizensUpgradeMarket Perform → Market Outperform$18

Total return (dividends reinvested) (LONA)

1Y (from 2025-10-16)5Y (from 2021-10-11)
Total return+44.5%-94.5%
S&P 500 (SPY)+18.1%+85.1%
Per year+44.7%-43.9%
Volatility (annualized)115.3%125.4%
Max drawdown-75.4% (Apr 2026→Sep 2026)-98.5% (Nov 2021→Apr 2025)

Key Statistics (as of October 16, 2026 at 05:19 UTC)

PriceUSD 5.29
Change▼ 1.86% (down)
Previous CloseUSD 5.39
OpenUSD 5.41
Day RangeUSD 4.91 – 5.42
52-Week RangeUSD 2.21 – 14.21
Volume35,246 shares
Market Cap$49.84M
ExchangeNCM

Technical Analysis (LONA)

Nexqual's technical model rates LONA "SELL" based on 1 bullish and 4 bearish signals across 127 daily candles, as of October 16, 2026 at 05:19 UTC.

Overall SignalSELL
RSI (14)43.75 (neutral)
vs SMA50Below (USD 6.66)
MACD-0.25 (negative)

Analyst Ratings (LONA)

Wall Street analysts rate LONA "Buy" based on 4 analysts, with a mean price target of USD 17.33 (range USD 15–20), per Nexqual as of October 16, 2026 at 05:19 UTC.

Consensus RatingBuy
Analyst Count4
Mean TargetUSD 17.33
High TargetUSD 20
Low TargetUSD 15
Buy / Hold / Sell4 / 0 / 0

Earnings (LONA)

Next Earnings Date2026-08-06
Revenue Estimate$0

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.8 vs est -1.36 ▲ beat
2026-03-31USD -1.73 vs est -2.5 ▲ beat
2025-12-31USD -18.92 vs est -1.27 ▼ miss
2025-09-30USD -1.68 vs est -1.22 ▼ miss

Source: Nexqual, October 16, 2026 at 05:19 UTC.

Financials & Fundamentals (LONA)

Gross Margin+0.00%
Operating Margin+0.00%
Profit Margin+0.00%
ROE-431.39%
Debt / Equity0.02
Current Ratio7.01
Total Cash$51.07M
Total Debt$577,000

Source: Nexqual, October 16, 2026 at 05:19 UTC.

Financial Health Score (LONA)

Nexqual rates LeonaBio, Inc.'s overall financial health "Mixed" across five dimensions, as of October 16, 2026 at 05:19 UTC.

GrowthMixed — No data
ProfitabilityWeak — Pre-revenue or very early stage
Balance SheetStrong — $51M cash, no debt
Cash FlowWeak — Operating cash flow -$62M (TTM)
EfficiencyCritical — ROE -431%, ROA -74.1%

Ownership (LONA)

Insider Ownership+4.07%
Institutional Ownership+87.66%
Shares Outstanding9.42M
Float4.73M
Short % of Float+0.26%

Source: Nexqual, October 16, 2026 at 05:19 UTC.

Leadership (LONA)

LeonaBio, Inc. is led by Mark J. Litton (age 57), President, CEO & Director, per Nexqual as of October 16, 2026 at 05:19 UTC.

President, CEO & DirectorMark J. Litton (age 57)
Chief Financial OfficerRobert Renninger (age 40)
Chief Scientific OfficerKevin Church (age 40)

Major Backers & Investors (LONA)

Notable institutional backers of LeonaBio, Inc. include Perceptive Advisors Llc, Adar1 Capital Management, LLC , Acorn Capital Advisors, LLC , according to Nexqual as of October 16, 2026 at 05:19 UTC.

Active Investors

InvestorStake
Perceptive Advisors Llc19.79%
Adar1 Capital Management, LLC 8.27%
Acorn Capital Advisors, LLC 6.76%
Commodore Capital Lp4.94%
NEA Management Company, LLC4.94%
TCG Crossover Management, LLC4.94%
Spruce Street Capital LP4.19%
Kalehua Capital Management LLC4.19%

Source: Nexqual, October 16, 2026 at 05:19 UTC.

Peers & Related Stocks

SymbolNamePriceChange
RYTMRhythm Pharmaceuticals, Inc.USD 87.97▲ 1.57%
BLTEBelite Bio, IncUSD 152.62▲ 0.49%
IOVAIovance Biotherapeutics, Inc.USD 14.72▲ 1.52%
PRAXPraxis Precision Medicines, IncUSD 248.24▲ 2.01%
IONSIonis Pharmaceuticals, Inc.USD 44.12▲ 4.11%
SYRESpyre Therapeutics, Inc.USD 80.1▼ 0.44%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 16, 2026 at 05:19 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt