Oruka Therapeutics, Inc. (ORKA) Stock Price & Analysis
Oruka Therapeutics, Inc. (ORKA) rose 4.48% to USD 66.93 as of June 10, 2026 at 02:33 UTC, according to Nexqual real-time market data.
ORKA last closed at USD 64.06; the session ranged USD 62.55–67.13 on volume of 1,427,446 shares. Market capitalization is $4.04B, with a 52-week range of USD 10.77–91 (NGM). Source: Nexqual, June 10, 2026 at 02:33 UTC.
Key Statistics (as of June 10, 2026 at 02:33 UTC)
| Price | USD 66.93 |
|---|---|
| Change | ▲ 4.48% (up) |
| Previous Close | USD 64.06 |
| Open | USD 65 |
| Day Range | USD 62.55 – 67.13 |
| 52-Week Range | USD 10.77 – 91 |
| Volume | 1,427,446 shares |
| Market Cap | $4.04B |
| Exchange | NGM |
Technical Analysis (ORKA)
Nexqual's technical model rates ORKA "BUY" based on 5 bullish and 2 bearish signals across 124 daily candles, as of June 10, 2026 at 02:33 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 57.3 (neutral) |
| vs SMA50 | Above (USD 62.55) |
| MACD | 0.06 (positive) |
Analyst Ratings (ORKA)
Wall Street analysts rate ORKA "Strong Buy" based on 12 analysts, with a mean price target of USD 142.17 (range USD 100–200), per Nexqual as of June 10, 2026 at 02:33 UTC.
| Consensus Rating | Strong Buy |
|---|---|
| Analyst Count | 12 |
| Mean Target | USD 142.17 |
| High Target | USD 200 |
| Low Target | USD 100 |
| Buy / Hold / Sell | 13 / 0 / 0 |
Earnings (ORKA)
| Next Earnings Date | 2026-08-10 |
|---|---|
| EPS Estimate | USD -0.5 |
| Revenue Estimate | $0 |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-03-31 | USD -0.48 vs est -0.54 ▲ beat |
| 2025-12-31 | USD -0.45 vs est -0.62 ▲ beat |
| 2025-09-30 | USD -0.55 vs est -0.52 ▼ miss |
| 2025-06-30 | USD -0.46 vs est -0.43 ▼ miss |
Source: Nexqual, June 10, 2026 at 02:33 UTC.
Financials & Fundamentals (ORKA)
| Gross Margin | +0.00% |
|---|---|
| Operating Margin | +0.00% |
| Profit Margin | +0.00% |
| ROE | -27.31% |
| Debt / Equity | 0.37 |
| Current Ratio | 23.76 |
| Total Cash | $388.83M |
| Total Debt | $1.81M |
| Free Cash Flow | $-56.13M |
Source: Nexqual, June 10, 2026 at 02:33 UTC.
Financial Health Score (ORKA)
Nexqual rates Oruka Therapeutics, Inc.'s overall financial health "Mixed" across five dimensions, as of June 10, 2026 at 02:33 UTC.
| Growth | Mixed — No data |
|---|---|
| Profitability | Weak — Pre-revenue or very early stage |
| Balance Sheet | Strong — $389M cash vs $2M debt, net cash position |
| Cash Flow | Weak — Operating cash flow -$91M |
| Efficiency | Critical — ROE -27%, ROA -18.9% |
Ownership (ORKA)
| Insider Ownership | +1.29% |
|---|---|
| Institutional Ownership | +88.54% |
| Shares Outstanding | 60.31M |
| Float | 51.05M |
| Short % of Float | +16.10% |
Source: Nexqual, June 10, 2026 at 02:33 UTC.
Leadership (ORKA)
Oruka Therapeutics, Inc. is led by Lawrence Otto Klein (age 42), President, CEO & Director, per Nexqual as of June 10, 2026 at 02:33 UTC.
| President, CEO & Director | Lawrence Otto Klein (age 42) |
|---|---|
| Chief Operating Officer | Laura Sandler (age 47) |
Major Backers & Investors (ORKA)
Notable institutional backers of Oruka Therapeutics, Inc. include FMR, LLC, Venrock Adviser, LLC, Fidelity, according to Nexqual as of June 10, 2026 at 02:33 UTC.
Active Investors
| Investor | Stake |
|---|---|
| FMR, LLC | 12.32% |
| Venrock Adviser, LLC | 6.88% |
| Fidelity | 6.44% |
| Fairmount Funds Management LLC | 6.14% |
| Viking Global | 4.42% |
| Paradigm Biocapital Advisors LP | 3.85% |
| RTW Investments LP | 3.41% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 7.36% |
| Vanguard Group | 6.08% |
| State Street | 4.09% |
Source: Nexqual, June 10, 2026 at 02:33 UTC.
From Oruka Therapeutics, Inc.'s Latest SEC 10-K Filing (filed 2026-03-12)
Key Strengths & Strategy (as disclosed to the SEC)
- We and Paragon have also filed, and may continue to file, patent applications relating to antibodies that target IL-17, including applications covering composition of matter, pharmaceutical formulations, and methods of use, including for ORKA-002.   We hold exclusive rights to ORKA-001 and ORKA-002, as well as the associated IL-23 and IL-17 patent rights, pursuant to license agreements with Paragon.
- Our strategy is to apply antibody engineering and format innovations to validated modes of action, which we believe will enable us to improve meaningfully upon the efficacy and dosing regimens of standard-of-care medicines while significantly reducing technical and biological risk.
- We believe this approach will enable us to improve meaningfully upon the efficacy and convenience of standard-of-care medicines while significantly reducing technical and biological risk.
Partnerships
- In September 2024, we exercised our exclusive option to acquire certain rights to ORKA-001, and in December 2024, we entered into a corresponding license agreement with Paragon pursuant to which Paragon granted us a royalty-bearing, world-wide, exclusive license to develop, manufacture, commercialize or otherwise exploit certain antibodies and products targeting IL-23 in all fields other than the field of inflammatory bowel disease.
- As of December 31, 2025, we have not entered into a license agreement with Paragon and Paruka related to this additional option agreement.   15     Cell Line License Agreement   In March 2024, we entered into the Cell Line License Agreement (the "Cell Line License Agreement") with WuXi Biologics Ireland Limited ("WuXi Biologics").
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| SYRE | Spyre Therapeutics, Inc. | USD 76.44 | ▲ 3.79% |
| DNTH | Dianthus Therapeutics, Inc. | USD 84.57 | ▲ 5.04% |
| APGE | Apogee Therapeutics, Inc. | USD 85 | ▼ 2.21% |
| ELVN | Enliven Therapeutics, Inc. | USD 36.11 | ▲ 4.03% |
| TNGX | Tango Therapeutics, Inc. | USD 31.56 | ▲ 56.08% |
Data source: Nexqual — real-time market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: June 10, 2026 at 02:33 UTC. This page is informational and not investment advice.