Palvella Therapeutics, Inc. (PVLA) Stock Price & Analysis

Palvella Therapeutics, Inc. (PVLA) closed at USD 127.34 on Thursday, October 15, 2026, up 3.88% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 122.58; the Oct 15, 2026 session ranged USD 122.51–129.49 on volume of 240,969 shares. Market capitalization is $1.83B, with a 52-week range of USD 68.96–161.38 (NGM). Source: Nexqual, retrieved October 16, 2026 at 05:20 UTC.

Also available as compact Markdown for AI agents: nexqual.com/PVLA.md

Key facts (PVLA)

Analysts (PVLA)

Consensus Buy (mean 2.00 on a 1–5 scale), 15 analysts; mean target USD 228.93 (low 205, high 267).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-12HC Wainwright & Co.Target loweredBuy$270 → $246
2026-09-21Chardan CapitalMaintainedBuy$240

Total return (dividends reinvested) (PVLA)

1Y (from 2025-10-16)5Y (from 2021-10-11)
Total return+74.1%-64.7%
S&P 500 (SPY)+18.1%+85.1%
Per year+74.4%-18.8%
Volatility (annualized)80.9%97.8%
Max drawdown-31.1% (Feb 2026→Jun 2026)-98.1% (Oct 2021→Jul 2024)

Key Statistics (as of October 16, 2026 at 05:20 UTC)

PriceUSD 127.34
Change▲ 3.88% (up)
Previous CloseUSD 122.58
OpenUSD 123.58
Day RangeUSD 122.51 – 129.49
52-Week RangeUSD 68.96 – 161.38
Volume240,969 shares
Market Cap$1.83B
ExchangeNGM

Technical Analysis (PVLA)

Nexqual's technical model rates PVLA "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 16, 2026 at 05:20 UTC.

Overall SignalSTRONG SELL
RSI (14)38.28 (neutral)
vs SMA50Below (USD 146.14)
MACD-5.56 (negative)

Analyst Ratings (PVLA)

Wall Street analysts rate PVLA "Buy" based on 15 analysts, with a mean price target of USD 228.93 (range USD 205–267), per Nexqual as of October 16, 2026 at 05:20 UTC.

Consensus RatingBuy
Analyst Count15
Mean TargetUSD 228.93
High TargetUSD 267
Low TargetUSD 205
Buy / Hold / Sell15 / 0 / 0

Earnings (PVLA)

Next Earnings Date2026-11-11
EPS EstimateUSD -1.74
Revenue Estimate$0

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -1.52 vs est -1.15 ▼ miss
2026-03-31USD -1.2 vs est -0.93 ▼ miss
2025-12-31USD -1.08 vs est -0.91 ▼ miss
2025-09-30USD -1.03 vs est -0.85 ▼ miss

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Financials & Fundamentals (PVLA)

Gross Margin+0.00%
Operating Margin+0.00%
Profit Margin+0.00%
ROE-46.63%
Debt / Equity0.1
Current Ratio21.18
Total Cash$250.58M
Total Debt$22.64M

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Financial Health Score (PVLA)

Nexqual rates Palvella Therapeutics, Inc.'s overall financial health "Mixed" across five dimensions, as of October 16, 2026 at 05:20 UTC.

GrowthMixed — No data
ProfitabilityWeak — Pre-revenue or very early stage
Balance SheetStrong — $251M cash vs $23M debt, net cash position
Cash FlowWeak — Operating cash flow -$37M (TTM)
EfficiencyCritical — ROE -47%, ROA -22.1%

Ownership (PVLA)

Insider Ownership+11.59%
Institutional Ownership+103.84%
Shares Outstanding14.41M
Float10.68M
Short % of Float+19.82%

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Leadership (PVLA)

Palvella Therapeutics, Inc. is led by Wesley H. Kaupinen, Founder, President, CEO & Director, per Nexqual as of October 16, 2026 at 05:20 UTC.

Founder, President, CEO & DirectorWesley H. Kaupinen
CFO, Corporate Secretary & TreasurerMatthew E. Korenberg (age 50)
Chief Operating OfficerKathleen Goin (age 54)
Chief Scientific OfficerJeffrey Martini (age 47)
Vice President of Investor Relations & Corporate AffairsMarcy B. Nanus

Major Backers & Investors (PVLA)

Notable institutional backers of Palvella Therapeutics, Inc. include Montanova Capital LLC, Jennison Associates LLC, Frazier Life Sciences Management, L.P. , according to Nexqual as of October 16, 2026 at 05:20 UTC.

Active Investors

InvestorStake
Montanova Capital LLC7.88%
Jennison Associates LLC6.67%
Frazier Life Sciences Management, L.P. 6.12%
First Light Asset Management, LLC5.36%
BVF Inc.4.67%
Price (T.Rowe) Associates Inc4.43%
Frontier Capital Management Company LLC3.32%

Index Funds (Passive)

FundStake
BlackRock8.31%
State Street7.04%
Vanguard Group6.27%

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Peers & Related Stocks

SymbolNamePriceChange
RYTMRhythm Pharmaceuticals, Inc.USD 87.97▲ 1.57%
BLTEBelite Bio, IncUSD 152.62▲ 0.49%
IOVAIovance Biotherapeutics, Inc.USD 14.72▲ 1.52%
PRAXPraxis Precision Medicines, IncUSD 248.24▲ 2.01%
IONSIonis Pharmaceuticals, Inc.USD 44.12▲ 4.11%
SYRESpyre Therapeutics, Inc.USD 80.1▼ 0.44%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 16, 2026 at 05:20 UTC. This page is informational and not investment advice.

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