Q32 Bio Inc. (QTTB) Stock Price & Analysis

Q32 Bio Inc. (QTTB) closed at USD 8.8 on Thursday, October 22, 2026, up 1.50% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 8.67; the Oct 22, 2026 session ranged USD 8.6–9.01 on volume of 363,636 shares. Market capitalization is $261.97M, with a 52-week range of USD 1.91–23.57 (NCM). Source: Nexqual, retrieved October 23, 2026 at 10:12 UTC.

Also available as compact Markdown for AI agents: nexqual.com/QTTB.md

Key facts (QTTB)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (QTTB)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$34.0M$3.2M$1.2M$0K$53.7M—
Operating income-$95.9M-$133M-$48.3M-$66.1M$16.9M$21.5M
Net income-$95.8M-$5.0M-$53.7M-$47.7M$29.8M$33.8M
EPS (diluted)-$31.14-$1.62-$153.96-$6.58$2.42—
Free cash flow-$112M-$115M-$18.7M-$67.8M-$33.5M—
Operating margin-282.4%-4154.6%-4174.3%—31.5%—
Net margin-281.9%-156.0%-4649.0%—55.5%—
Revenue growth+1157.3%-90.6%-64.0%-100.0%——
Cash + short-term investments$156M$175M$25.6M$78.0M——
Total debt—$30.0M$38.6M$0K——

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (QTTB)

P/E 7.8x · P/B 2.5x · Earnings yield 12.90%

P/E at fiscal year-ends: Dec 2025 1.4x.

Analysts (QTTB)

Consensus Buy (mean 1.86 on a 1–5 scale), 7 analysts; mean target USD 39.67 (low 29, high 59).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-12Leerink PartnersInitiatedOutperform$40
2026-09-28JefferiesInitiatedBuy$29
2026-08-24Morgan StanleyInitiatedOverweight$34
2026-07-28HC Wainwright & Co.Target raisedBuy$13 → $36
2026-07-13OppenheimerTarget raisedOutperform$20 → $40
2026-07-13Wells FargoUpgradeEqual-Weight → Overweight$66

Total return (dividends reinvested) (QTTB)

1Y (from 2025-10-23)5Y (from 2021-10-18)
Total return+214.3%-91.8%
S&P 500 (SPY)+14.9%+80.3%
Per year+215.5%-39.4%
Volatility (annualized)141.8%134.7%
Max drawdown-64.8% (Jul 2026→Oct 2026)-98.8% (Nov 2021→Jun 2025)

Companies that name QTTB in their SEC reports

Relationship to QTTBCompanyFilingSentence
partnerAkebia Therapeutics, Inc. (AKBA)10-K Feb 26, 2026“In November 2025, we entered into an asset purchase agreement with Q32 Bio Inc. and Q32 Bio Operations Inc., together Q32, pursuant to which we purchased and assumed substantially all assets and liabilities of Q32 and its”

QTTB analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.33$-0.38-14.0%$07
Next quarter (ends Dec 2026)$-0.30$-0.37-18.8%$333,3307
Current fiscal year (ends Dec 2026)$-1.50$-1.74-13.7%$333,3307
Next fiscal year (ends Dec 2027)$-2.27$-1.97+15.0%$833,3307

Key Statistics (as of October 23, 2026 at 10:12 UTC)

PriceUSD 8.8
Change▲ 1.50% (up)
Previous CloseUSD 8.67
OpenUSD 8.67
Day RangeUSD 8.6 – 9.01
52-Week RangeUSD 1.91 – 23.57
Volume363,636 shares
Market Cap$261.97M
ExchangeNCM

Technical Analysis (QTTB)

Nexqual's technical model rates QTTB "SELL" based on 2 bullish and 4 bearish signals across 127 daily candles, as of October 23, 2026 at 10:12 UTC.

Overall SignalSELL
RSI (14)45.66 (neutral)
vs SMA50Below (USD 11.26)
MACD-0.72 (negative)

Analyst Ratings (QTTB)

Wall Street analysts rate QTTB "Buy" based on 7 analysts, with a mean price target of USD 39.67 (range USD 29–59), per Nexqual as of October 23, 2026 at 10:12 UTC.

Consensus RatingBuy
Analyst Count7
Mean TargetUSD 39.67
High TargetUSD 59
Low TargetUSD 29
Buy / Hold / Sell7 / 0 / 0

Earnings (QTTB)

Revenue Estimate$0

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.44 vs est -0.54 ▲ beat
2026-03-31USD -0.54 vs est -0.68 ▲ beat
2025-12-31USD 4.58 vs est -0.86 ▲ beat
2025-09-30USD -0.6 vs est -1.19 ▲ beat

Source: Nexqual, October 23, 2026 at 10:12 UTC.

Financials & Fundamentals (QTTB)

Total Revenue$53.74M
Gross Margin+73.30%
Operating Margin+39.94%
Profit Margin+62.87%
ROE+72.14%
Debt / Equity0.05
Current Ratio20.3
Total Cash$106.27M
Total Debt$5.30M
Free Cash Flow (fiscal year ended Dec 2025, SEC 10-K)-$33.54M (-62.4% of revenue)

Source: Nexqual, October 23, 2026 at 10:12 UTC.

Financial Health Score (QTTB)

Nexqual rates Q32 Bio Inc.'s overall financial health "Solid" across five dimensions, as of October 23, 2026 at 10:12 UTC.

GrowthMixed — No data
ProfitabilityStrong — Gross margin 73%, operating 40% (last 12 months)
Balance SheetStrong — $106M cash vs $5M debt, net cash position
Cash FlowWeak — FCF negative: -$34M (FY ended Dec 2025, 10-K), burning cash
EfficiencyStrong — ROE 72%, ROA 14.7%

Ownership (QTTB)

Insider Ownership+2.08%
Institutional Ownership+87.72%
Shares Outstanding29.77M
Float12.72M
Short % of Float+22.29%

Source: Nexqual, October 23, 2026 at 10:12 UTC.

Leadership (QTTB)

Q32 Bio Inc. is led by Jodie Pope Morrison, CEO & Director, per Nexqual as of October 23, 2026 at 10:12 UTC.

CEO & DirectorJodie Pope Morrison
CFO & PresidentLee H. Kalowski
Co-founder, Chief Scientific Officer & President of ResearchShelia M. Violette

Major Backers & Investors (QTTB)

Notable institutional backers of Q32 Bio Inc. include Orbimed Advisors LLC., Boxer Capital Management, LLC, Atlas Venture Life Science Advisors, LLC , according to Nexqual as of October 23, 2026 at 10:12 UTC.

Active Investors

InvestorStake
Orbimed Advisors LLC.13.87%
Boxer Capital Management, LLC10.58%
Atlas Venture Life Science Advisors, LLC 9.13%
BVF Inc.7.89%
RA Capital Management, L.P.7.84%
Point72 Asset Management, L.P.3.94%
Opaleye Management Inc.3.13%
Logos Global Management LP2.69%

Source: Nexqual, October 23, 2026 at 10:12 UTC.

Peers & Related Stocks

SymbolNamePriceChange
RYTMRhythm Pharmaceuticals, Inc.USD 90.9▲ 2.57%
LGNDLigand Pharmaceuticals IncorporUSD 307.82▼ 2.21%
IOVAIovance Biotherapeutics, Inc.USD 14.14▼ 3.28%
PRAXPraxis Precision Medicines, IncUSD 258.92▲ 0.96%
IONSIonis Pharmaceuticals, Inc.USD 43.91▼ 0.81%
ABVXAbivax SAUSD 90.23▼ 3.49%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 10:12 UTC. This page is informational and not investment advice.

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