Arcus Biosciences, Inc. (RCUS) Stock Price & Analysis
Arcus Biosciences, Inc. (RCUS) closed at USD 19.36 on Thursday, October 22, 2026, up 1.36% on the day. The US market is currently closed (pre-market); this is not a live price.
The prior close was USD 19.1; the Oct 22, 2026 session ranged USD 17.43–19.62 on volume of 8,370,959 shares. Market capitalization is $2.43B, with a 52-week range of USD 16.41–31.74 (NYQ). Source: Nexqual, retrieved October 23, 2026 at 09:15 UTC.
Also available as compact Markdown for AI agents: nexqual.com/RCUS.md
Key facts (RCUS)
- Last four reported quarters (through Jun 30, 2026): revenue $117M, net income -$460M (-393.2% margin), free cash flow -$475M (SEC filings).
- Insider open-market sales, last ~7 months: 5 Form 4 filings, $3.3M; 0 not under a Rule 10b5-1 plan ($0K); 1 by opportunistic insiders (0 outside 10b5-1 plans), 2 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.07 on a 1–5 scale) (15 analysts), mean target USD 41 (range 23–50).
- Total return with dividends: 1Y +15.4% vs S&P 500 +14.9%; 5Y -45.2% vs S&P 500 +80.3%.
- Next earnings: 2026-11-04, EPS estimate USD -0.89, revenue estimate $8.3M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (RCUS)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $383M | $112M | $117M | $258M | $247M | $117M |
| Operating income | $54.0M | -$280M | -$340M | -$330M | -$386M | -$486M |
| Net income | $53.0M | -$267M | -$307M | -$283M | -$353M | -$460M |
| EPS (diluted) | $0.71 | -$3.71 | -$4.15 | -$3.14 | -$3.29 | — |
| Free cash flow | -$282M | $432M | -$330M | -$176M | -$484M | -$475M |
| Operating margin | 14.1% | -250.0% | -290.6% | -127.9% | -156.3% | -415.4% |
| Net margin | 13.8% | -238.4% | -262.4% | -109.7% | -142.9% | -393.2% |
| Revenue growth | +391.0% | -70.8% | +4.5% | +120.5% | -4.3% | — |
| Cash + short-term investments | $499M | $1.01B | $759M | $978M | $981M | — |
| Total debt | — | — | $0K | $48.0M | $99.0M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (RCUS)
P/S 20.8x · EV/Sales 15.7x · P/B 5.3x · FCF yield -19.51% · Earnings yield -18.89% · Net cash $601M · EV $1.83B
Insider sales (SEC Form 4, open-market, last ~7 months) (RCUS)
5 of 5 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-08-21 | Azoy Alexander | Chief Accounting Officer | 2,827 | $85K | 6.7% | Yes | Routine (sold in Dec each year 2023–2025; this trade is outside those months) |
| 2026-07-09…2026-07-10 | Jaen Juan C. | President | 68,569 | $2.0M | 5.4% | Yes | Too little history (no open-market trades in 2023) |
| 2026-06-22…2026-06-24 | Jaen Juan C. | President | 31,431 | $878K | 2.4% | Yes (adopted February 27, 2026) | Too little history (no open-market trades in 2023) |
| 2026-06-01 | Azoy Alexander | Chief Accounting Officer | 2,562 | $66K | 6.1% | Yes | Routine (sold in Dec each year 2023–2025; this trade is outside those months) |
| 2026-05-11 | Goeltz Ii Robert C. | Chief Financial Officer | 7,763 | $199K | 8.4% | Yes | Opportunistic (traded every year 2023–2025, no repeating month) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (RCUS)
Consensus Buy (mean 2.07 on a 1–5 scale), 15 analysts; mean target USD 41 (low 23, high 50).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-21 | Citigroup | Target raised | Buy | $45 → $50 |
| 2026-10-21 | Truist Securities | Target raised | Buy | $40 → $41 |
| 2026-10-21 | Wedbush | Target raised | Outperform | $43 → $49 |
| 2026-10-16 | William Blair | Initiated | Outperform | |
| 2026-10-14 | JP Morgan | Initiated | Overweight | $41 |
| 2026-09-30 | Wedbush | Reiterated | Outperform | $43 |
| 2026-09-16 | TD Cowen | Initiated | Buy | |
| 2026-09-08 | Truist Securities | Target raised | Buy | $35 → $40 |
| 2026-08-06 | Wells Fargo | Target raised | Equal-Weight | $23 → $26 |
| 2026-08-06 | Wedbush | Target raised | Outperform | $41 → $43 |
| 2026-07-20 | HC Wainwright & Co. | Target raised | Buy | $32 → $45 |
Total return (dividends reinvested) (RCUS)
| 1Y (from 2025-10-23) | 5Y (from 2021-10-18) | |
|---|---|---|
| Total return | +15.4% | -45.2% |
| S&P 500 (SPY) | +14.9% | +80.3% |
| Per year | +15.4% | -11.3% |
| Volatility (annualized) | 62.9% | 62.3% |
| Max drawdown | -39.5% (Aug 2026→Oct 2026) | -85.5% (Nov 2021→Mar 2025) |
RCUS revenue by product line (quarter ended Jun 30, 2026)
| Line | Revenue | Share of total | YoY |
|---|---|---|---|
| Other collaboration | $25.0M | 61.0% | +212.5% |
| License and development services | $16.0M | 39.0% | -89.5% |
| Total revenue | $41.0M | 100% | — |
As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).
RCUS suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | GILEAD SCIENCES, INC. (GILD) | “•We expect to depend on our collaboration with Gilead for the research, development, manufacture and commercialization of certain of our investigational products.” |
| Partner | Taiho Pharmaceutical | “With respect to quemliclustat, domvanalimab and zimberelimab and subject to timely exercise of Gilead's and Taiho's respective option rights to other molecules in our pipeline, as discussed below, Gilead has certain commercialization rights under the Gilead Collaboration Agreement, and Taiho has commercial rights in Japan and certain other Asian countries based on the Option and License Agreement that we entered i…” |
| Partner | WuXi | “Our PD-1 license agreement (the "WuXi PD-1 Agreement") with WuXi Biologics Ireland Limited ("WuXi Biologics"), which we entered into in 2017 as subsequently amended, provides us with an exclusive license to (i) develop, use and manufacture products that include an anti-PD-1 antibody, including zimberelimab, throughout the world and (ii) commercialize any such products, throughout the world except in Greater China.” |
| Partner | ASTRAZENECA PLC (AZN) | “There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…” |
| Partner | Hercules Capital, Inc. (HTGC) | “•Our operating activities may be restricted as a result of covenants related to the indebtedness under our loan and security agreement with Hercules Capital, Inc., as amended, and we may be required to repay the outstanding indebtedness in an event of default, which could have a materially adverse effect on our business.” |
| Partner | Abmuno Therapeutics | “In 2016, we entered into a license agreement (the "Abmuno Agreement") with Abmuno Therapeutics LLC ("Abmuno") for a worldwide exclusive license to develop, use, manufacture, and commercialize products that include an anti-TIGIT antibody, including domvanalimab.” |
| Partner | Merck (MRK) | “There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…” |
| Partner | NOVARTIS AG (NVS) | “There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…” |
| Partner | Pfizer (PFE) | “There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…” |
| Partner | REGENERON PHARMACEUTICALS, INC. (REGN) | “There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…” |
| Partner | BVF Partners | “We have a liability for sale of future royalties which consists of the current balance of estimated contingent milestone and royalty payments under our agreement with BVF.” |
| Partner | WuXi Biologics Ireland | “Our PD-1 license agreement (the "WuXi PD-1 Agreement") with WuXi Biologics Ireland Limited ("WuXi Biologics"), which we entered into in 2017 as subsequently amended, provides us with an exclusive license to (i) develop, use and manufacture products that include an anti-PD-1 antibody, including zimberelimab, throughout the world and (ii) commercialize any such products, throughout the world except in Greater China.” |
| Competitor | AbbVie (ABBV) | “For our inflammation and immunology portfolio, we will be competing against large pharmaceutical and biotechnology companies with established products, such as Dupixent®, which is marketed by Sanofi and Regeneron, Xolair®, which is marketed by Genentech and Novartis, and Humira®, which is marketed by Abbvie.” |
Quoted from the company's 10-K filed Feb 25, 2026.
Companies that name RCUS in their SEC reports
| Relationship to RCUS | Company | Filing | Sentence |
|---|---|---|---|
| partner | GILEAD SCIENCES, INC. (GILD) | 10-K Feb 24, 2026 | “(1) For additional information regarding our collaborations with Merck, Arcellx and Arcus, see Note 7.” |
RCUS analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-0.89 | $-0.83 | +8.1% | $8.3M | 9 |
| Next quarter (ends Dec 2026) | $-0.84 | $-0.74 | +13.1% | $6.0M | 9 |
| Current fiscal year (ends Dec 2026) | $-3.52 | $-3.48 | +1.0% | $73.1M | 9 |
| Next fiscal year (ends Dec 2027) | $-3.12 | $-3.10 | +0.7% | $56.5M | 9 |
RCUS options: expected move
Options price a move of about ±14.9% (±$2.88) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±5.8% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 28 | 63.9% | ±14.9% |
| Dec 18, 2026 | 56 | 84.7% | ±27.0% |
| Jan 15, 2027 | 84 | 74.5% | ±30.9% |
| Mar 19, 2027 | 147 | 60.8% | ±31.0% |
| Apr 16, 2027 | 175 | 61.1% | ±33.8% |
30-day implied volatility 67.1% vs 79.1% realized over the last 30 trading days. Put/call ratio (volume) 1.99. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 23, 2026 at 09:15 UTC)
| Price | USD 19.36 |
|---|---|
| Change | ▲ 1.36% (up) |
| Previous Close | USD 19.1 |
| Open | USD 17.43 |
| Day Range | USD 17.43 – 19.62 |
| 52-Week Range | USD 16.41 – 31.74 |
| Volume | 8,370,959 shares |
| Market Cap | $2.43B |
| Exchange | NYQ |
Technical Analysis (RCUS)
Nexqual's technical model rates RCUS "SELL" based on 2 bullish and 5 bearish signals across 127 daily candles, as of October 23, 2026 at 09:15 UTC.
| Overall Signal | SELL |
|---|---|
| RSI (14) | 27.72 (oversold) |
| vs SMA50 | Below (USD 26.33) |
| MACD | -1.52 (negative) |
Analyst Ratings (RCUS)
Wall Street analysts rate RCUS "Buy" based on 15 analysts, with a mean price target of USD 41 (range USD 23–50), per Nexqual as of October 23, 2026 at 09:15 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 15 |
| Mean Target | USD 41 |
| High Target | USD 50 |
| Low Target | USD 23 |
| Buy / Hold / Sell | 13 / 2 / 0 |
Earnings (RCUS)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD -0.89 |
| Revenue Estimate | $8.27M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -0.72 vs est -0.81 ▲ beat |
| 2026-03-31 | USD -1.02 vs est -0.83 ▼ miss |
| 2025-12-31 | USD -0.89 vs est -1.08 ▲ beat |
| 2025-09-30 | USD -1.27 vs est -1.29 ▲ beat |
Source: Nexqual, October 23, 2026 at 09:15 UTC.
Financials & Fundamentals (RCUS)
| Total Revenue | $117.00M |
|---|---|
| Revenue Growth (latest quarter, YoY) | -74.40% |
| Gross Margin | +0.00% |
| Operating Margin | -234.15% |
| Profit Margin | +0.00% |
| ROE | -90.82% |
| Debt / Equity | 0.51 |
| Current Ratio | 3.82 |
| Total Cash | $702.00M |
| Total Debt | $238.00M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$475.00M (-406.0% of revenue) |
Source: Nexqual, October 23, 2026 at 09:15 UTC.
Financial Health Score (RCUS)
Nexqual rates Arcus Biosciences, Inc.'s overall financial health "Weak" across five dimensions, as of October 23, 2026 at 09:15 UTC.
| Growth | Weak — Revenue -4% YoY (annual), declining |
|---|---|
| Profitability | Critical — Heavily loss-making — early-stage company |
| Balance Sheet | Strong — $702M cash and investments vs $101M debt (Jun 2026, SEC), net cash |
| Cash Flow | Weak — FCF negative: -$475M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE -91%, ROA -30.4% |
Ownership (RCUS)
| Insider Ownership | +25.95% |
|---|---|
| Institutional Ownership | +67.41% |
| Shares Outstanding | 125.77M |
| Float | 90.53M |
| Short % of Float | +16.81% |
Source: Nexqual, October 23, 2026 at 09:15 UTC.
Leadership (RCUS)
Arcus Biosciences, Inc. is led by Terry J. Rosen, Co-Founder, Chairman & CEO, per Nexqual as of October 23, 2026 at 09:15 UTC.
| Co-Founder, Chairman & CEO | Terry J. Rosen |
|---|---|
| Co- Founder & President | Juan Carlos Jaen |
| Principal Financial Officer & CFO | Robert C. Goeltz |
| Chief Scientific Officer | Jonathan Yingling |
| Vice President of Investor Relations & Strategy | Pia Eaves |
Major Backers & Investors (RCUS)
Notable institutional backers of Arcus Biosciences, Inc. include Gilead Sciences Inc, Wellington Management, Montanova Capital LLC, according to Nexqual as of October 23, 2026 at 09:15 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Gilead Sciences Inc | 24.68% |
| Wellington Management | 4.63% |
| Montanova Capital LLC | 3.75% |
| FMR, LLC | 3.18% |
| Citadel | 2.46% |
| Woodline Partners LP | 2.36% |
| Fidelity | 1.44% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 12.89% |
| Vanguard Group | 6.56% |
| State Street | 4.74% |
Source: Nexqual, October 23, 2026 at 09:15 UTC.
From Arcus Biosciences, Inc.'s Latest SEC 10-K Filing (filed 2026-02-25)
Key Strengths & Strategy (as disclosed to the SEC)
- In the U.S., the FDA regulates under the Federal Food, Drug, and Cosmetic Act (the "FDCA"), and biologics under the FDCA and the Public Health Service Act (the "PHSA"), and their respective implementing regulations.
- The FDA has various programs, including Fast Track, Breakthrough Therapy, priority review, accelerated approval, and Commissioner's National Priority Voucher ("CNPV"), which are intended to expedite or simplify the process for reviewing investigational products designed to address serious or life threatening conditions, or provide for the approval of a such investigational products on the basis of an effect on a surrogate or intermediate endpoint.
- Our commercial success depends in large part on our ability to obtain and maintain patent protection in the U.S. and other countries for our investigational products, to operate without infringing valid and enforceable patents and proprietary rights of others, and to prevent others from infringing on our proprietary or intellectual property rights.
- We seek to protect our proprietary position by filing, in the U.S. and other foreign jurisdictions, patent applications intended to cover the composition of matter of our investigational products, their methods of use, and related discoveries, technologies, inventions and improvements that may be commercially important to our business.
Partnerships
- For our anti-PD-1 antibody, zimberelimab, multiple large pharmaceutical companies have already received regulatory approvals for their anti-PD-1/PD-L1 antibodies, including AstraZeneca, BeiGene/Novartis, Bristol-Myers Squibb, Merck, Pfizer in partnership with Merck KGaA, Regeneron in partnership with Sanofi Genzyme and Roche/Genentech, and there are also many other anti-PD-1 and anti-PD-L1 antibodies in clinical development.
- Further, with respect to domvanalimab, we remain eligible to receive up to $500 million in milestone payments.
Legal & Regulatory Risks (Item 1A, quoted)
- Our manufacturing partners are subject to extensive regulation. In the event any of our manufacturers fail to comply with such regulations or perform its obligations, our business may be adversely affected and we may need to delay or halt the development of our investigational products.
- Our employees, clinical trial investigators, CROs, consultants, vendors, collaboration partners and any potential commercial partners may engage in misconduct or other improper activities, including non-compliance with regulatory standards and requirements and insider trading.
- We may become involved in lawsuits alleging that we have infringed the intellectual property rights of third parties or to protect or enforce our patents or other intellectual property, which litigation could be expensive, time consuming and adversely affect our ability to develop or commercialize our investigational products.
- We may be subject to claims that our employees, consultants or independent contractors have wrongfully used or disclosed confidential information of third parties.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| RYTM | Rhythm Pharmaceuticals, Inc. | USD 90.9 | ▲ 2.57% |
| LGND | Ligand Pharmaceuticals Incorpor | USD 307.82 | ▼ 2.21% |
| IOVA | Iovance Biotherapeutics, Inc. | USD 14.14 | ▼ 3.28% |
| PRAX | Praxis Precision Medicines, Inc | USD 258.92 | ▲ 0.96% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 43.91 | ▼ 0.81% |
| ABVX | Abivax SA | USD 90.23 | ▼ 3.49% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 09:15 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt