Arcus Biosciences, Inc. (RCUS) Stock Price & Analysis

Arcus Biosciences, Inc. (RCUS) closed at USD 19.36 on Thursday, October 22, 2026, up 1.36% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 19.1; the Oct 22, 2026 session ranged USD 17.43–19.62 on volume of 8,370,959 shares. Market capitalization is $2.43B, with a 52-week range of USD 16.41–31.74 (NYQ). Source: Nexqual, retrieved October 23, 2026 at 09:15 UTC.

Also available as compact Markdown for AI agents: nexqual.com/RCUS.md

Key facts (RCUS)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (RCUS)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$383M$112M$117M$258M$247M$117M
Operating income$54.0M-$280M-$340M-$330M-$386M-$486M
Net income$53.0M-$267M-$307M-$283M-$353M-$460M
EPS (diluted)$0.71-$3.71-$4.15-$3.14-$3.29—
Free cash flow-$282M$432M-$330M-$176M-$484M-$475M
Operating margin14.1%-250.0%-290.6%-127.9%-156.3%-415.4%
Net margin13.8%-238.4%-262.4%-109.7%-142.9%-393.2%
Revenue growth+391.0%-70.8%+4.5%+120.5%-4.3%—
Cash + short-term investments$499M$1.01B$759M$978M$981M—
Total debt——$0K$48.0M$99.0M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (RCUS)

P/S 20.8x · EV/Sales 15.7x · P/B 5.3x · FCF yield -19.51% · Earnings yield -18.89% · Net cash $601M · EV $1.83B

Insider sales (SEC Form 4, open-market, last ~7 months) (RCUS)

5 of 5 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-08-21Azoy AlexanderChief Accounting Officer2,827$85K6.7%YesRoutine (sold in Dec each year 2023–2025; this trade is outside those months)
2026-07-09…2026-07-10Jaen Juan C.President68,569$2.0M5.4%YesToo little history (no open-market trades in 2023)
2026-06-22…2026-06-24Jaen Juan C.President31,431$878K2.4%Yes (adopted February 27, 2026)Too little history (no open-market trades in 2023)
2026-06-01Azoy AlexanderChief Accounting Officer2,562$66K6.1%YesRoutine (sold in Dec each year 2023–2025; this trade is outside those months)
2026-05-11Goeltz Ii Robert C.Chief Financial Officer7,763$199K8.4%YesOpportunistic (traded every year 2023–2025, no repeating month)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (RCUS)

Consensus Buy (mean 2.07 on a 1–5 scale), 15 analysts; mean target USD 41 (low 23, high 50).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-21CitigroupTarget raisedBuy$45 → $50
2026-10-21Truist SecuritiesTarget raisedBuy$40 → $41
2026-10-21WedbushTarget raisedOutperform$43 → $49
2026-10-16William BlairInitiatedOutperform
2026-10-14JP MorganInitiatedOverweight$41
2026-09-30WedbushReiteratedOutperform$43
2026-09-16TD CowenInitiatedBuy
2026-09-08Truist SecuritiesTarget raisedBuy$35 → $40
2026-08-06Wells FargoTarget raisedEqual-Weight$23 → $26
2026-08-06WedbushTarget raisedOutperform$41 → $43
2026-07-20HC Wainwright & Co.Target raisedBuy$32 → $45

Total return (dividends reinvested) (RCUS)

1Y (from 2025-10-23)5Y (from 2021-10-18)
Total return+15.4%-45.2%
S&P 500 (SPY)+14.9%+80.3%
Per year+15.4%-11.3%
Volatility (annualized)62.9%62.3%
Max drawdown-39.5% (Aug 2026→Oct 2026)-85.5% (Nov 2021→Mar 2025)

RCUS revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Other collaboration$25.0M61.0%+212.5%
License and development services$16.0M39.0%-89.5%
Total revenue$41.0M100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

RCUS suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerGILEAD SCIENCES, INC. (GILD)“•We expect to depend on our collaboration with Gilead for the research, development, manufacture and commercialization of certain of our investigational products.”
PartnerTaiho Pharmaceutical“With respect to quemliclustat, domvanalimab and zimberelimab and subject to timely exercise of Gilead's and Taiho's respective option rights to other molecules in our pipeline, as discussed below, Gilead has certain commercialization rights under the Gilead Collaboration Agreement, and Taiho has commercial rights in Japan and certain other Asian countries based on the Option and License Agreement that we entered i…”
PartnerWuXi“Our PD-1 license agreement (the "WuXi PD-1 Agreement") with WuXi Biologics Ireland Limited ("WuXi Biologics"), which we entered into in 2017 as subsequently amended, provides us with an exclusive license to (i) develop, use and manufacture products that include an anti-PD-1 antibody, including zimberelimab, throughout the world and (ii) commercialize any such products, throughout the world except in Greater China.”
PartnerASTRAZENECA PLC (AZN)“There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…”
PartnerHercules Capital, Inc. (HTGC)“•Our operating activities may be restricted as a result of covenants related to the indebtedness under our loan and security agreement with Hercules Capital, Inc., as amended, and we may be required to repay the outstanding indebtedness in an event of default, which could have a materially adverse effect on our business.”
PartnerAbmuno Therapeutics“In 2016, we entered into a license agreement (the "Abmuno Agreement") with Abmuno Therapeutics LLC ("Abmuno") for a worldwide exclusive license to develop, use, manufacture, and commercialize products that include an anti-TIGIT antibody, including domvanalimab.”
PartnerMerck (MRK)“There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…”
PartnerNOVARTIS AG (NVS)“There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…”
PartnerPfizer (PFE)“There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…”
PartnerREGENERON PHARMACEUTICALS, INC. (REGN)“There are many other companies that have commercialized and/or are developing oncology treatments for cancer including large pharmaceutical and biotechnology companies such as AstraZeneca, BeiGene, Ltd. ("BeiGene"), The Bristol-Myer Squibb Company ("Bristol-Myers Squibb"), GlaxoSmithKline plc ("GSK"), Merck, Novartis Inc. ("Novartis"), Pfizer Inc. ("Pfizer"), Regeneron Pharmaceuticals, Inc. ("Regeneron") in partne…”
PartnerBVF Partners“We have a liability for sale of future royalties which consists of the current balance of estimated contingent milestone and royalty payments under our agreement with BVF.”
PartnerWuXi Biologics Ireland“Our PD-1 license agreement (the "WuXi PD-1 Agreement") with WuXi Biologics Ireland Limited ("WuXi Biologics"), which we entered into in 2017 as subsequently amended, provides us with an exclusive license to (i) develop, use and manufacture products that include an anti-PD-1 antibody, including zimberelimab, throughout the world and (ii) commercialize any such products, throughout the world except in Greater China.”
CompetitorAbbVie (ABBV)“For our inflammation and immunology portfolio, we will be competing against large pharmaceutical and biotechnology companies with established products, such as Dupixent®, which is marketed by Sanofi and Regeneron, Xolair®, which is marketed by Genentech and Novartis, and Humira®, which is marketed by Abbvie.”

Quoted from the company's 10-K filed Feb 25, 2026.

Companies that name RCUS in their SEC reports

Relationship to RCUSCompanyFilingSentence
partnerGILEAD SCIENCES, INC. (GILD)10-K Feb 24, 2026“(1) For additional information regarding our collaborations with Merck, Arcellx and Arcus, see Note 7.”

RCUS analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.89$-0.83+8.1%$8.3M9
Next quarter (ends Dec 2026)$-0.84$-0.74+13.1%$6.0M9
Current fiscal year (ends Dec 2026)$-3.52$-3.48+1.0%$73.1M9
Next fiscal year (ends Dec 2027)$-3.12$-3.10+0.7%$56.5M9

RCUS options: expected move

Options price a move of about ±14.9% (±$2.88) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±5.8% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262863.9%±14.9%
Dec 18, 20265684.7%±27.0%
Jan 15, 20278474.5%±30.9%
Mar 19, 202714760.8%±31.0%
Apr 16, 202717561.1%±33.8%

30-day implied volatility 67.1% vs 79.1% realized over the last 30 trading days. Put/call ratio (volume) 1.99. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 23, 2026 at 09:15 UTC)

PriceUSD 19.36
Change▲ 1.36% (up)
Previous CloseUSD 19.1
OpenUSD 17.43
Day RangeUSD 17.43 – 19.62
52-Week RangeUSD 16.41 – 31.74
Volume8,370,959 shares
Market Cap$2.43B
ExchangeNYQ

Technical Analysis (RCUS)

Nexqual's technical model rates RCUS "SELL" based on 2 bullish and 5 bearish signals across 127 daily candles, as of October 23, 2026 at 09:15 UTC.

Overall SignalSELL
RSI (14)27.72 (oversold)
vs SMA50Below (USD 26.33)
MACD-1.52 (negative)

Analyst Ratings (RCUS)

Wall Street analysts rate RCUS "Buy" based on 15 analysts, with a mean price target of USD 41 (range USD 23–50), per Nexqual as of October 23, 2026 at 09:15 UTC.

Consensus RatingBuy
Analyst Count15
Mean TargetUSD 41
High TargetUSD 50
Low TargetUSD 23
Buy / Hold / Sell13 / 2 / 0

Earnings (RCUS)

Next Earnings Date2026-11-04
EPS EstimateUSD -0.89
Revenue Estimate$8.27M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.72 vs est -0.81 ▲ beat
2026-03-31USD -1.02 vs est -0.83 ▼ miss
2025-12-31USD -0.89 vs est -1.08 ▲ beat
2025-09-30USD -1.27 vs est -1.29 ▲ beat

Source: Nexqual, October 23, 2026 at 09:15 UTC.

Financials & Fundamentals (RCUS)

Total Revenue$117.00M
Revenue Growth (latest quarter, YoY)-74.40%
Gross Margin+0.00%
Operating Margin-234.15%
Profit Margin+0.00%
ROE-90.82%
Debt / Equity0.51
Current Ratio3.82
Total Cash$702.00M
Total Debt$238.00M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$475.00M (-406.0% of revenue)

Source: Nexqual, October 23, 2026 at 09:15 UTC.

Financial Health Score (RCUS)

Nexqual rates Arcus Biosciences, Inc.'s overall financial health "Weak" across five dimensions, as of October 23, 2026 at 09:15 UTC.

GrowthWeak — Revenue -4% YoY (annual), declining
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $702M cash and investments vs $101M debt (Jun 2026, SEC), net cash
Cash FlowWeak — FCF negative: -$475M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -91%, ROA -30.4%

Ownership (RCUS)

Insider Ownership+25.95%
Institutional Ownership+67.41%
Shares Outstanding125.77M
Float90.53M
Short % of Float+16.81%

Source: Nexqual, October 23, 2026 at 09:15 UTC.

Leadership (RCUS)

Arcus Biosciences, Inc. is led by Terry J. Rosen, Co-Founder, Chairman & CEO, per Nexqual as of October 23, 2026 at 09:15 UTC.

Co-Founder, Chairman & CEOTerry J. Rosen
Co- Founder & PresidentJuan Carlos Jaen
Principal Financial Officer & CFORobert C. Goeltz
Chief Scientific OfficerJonathan Yingling
Vice President of Investor Relations & StrategyPia Eaves

Major Backers & Investors (RCUS)

Notable institutional backers of Arcus Biosciences, Inc. include Gilead Sciences Inc, Wellington Management, Montanova Capital LLC, according to Nexqual as of October 23, 2026 at 09:15 UTC.

Active Investors

InvestorStake
Gilead Sciences Inc24.68%
Wellington Management4.63%
Montanova Capital LLC3.75%
FMR, LLC3.18%
Citadel2.46%
Woodline Partners LP2.36%
Fidelity1.44%

Index Funds (Passive)

FundStake
BlackRock12.89%
Vanguard Group6.56%
State Street4.74%

Source: Nexqual, October 23, 2026 at 09:15 UTC.

From Arcus Biosciences, Inc.'s Latest SEC 10-K Filing (filed 2026-02-25)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 09:15 UTC. This page is informational and not investment advice.

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