Replimune Group, Inc. (REPL) Stock Price & Analysis
Replimune Group, Inc. (REPL) closed at USD 16.06 on Wednesday, October 28, 2026, up 23.07% on the day. The US market is currently closed (after-hours); this is not a live price.
The prior close was USD 13.05; the Oct 28, 2026 session ranged USD 12.5–16.75 on volume of 7,277,843 shares. Market capitalization is $1.51B, with a 52-week range of USD 1.5–16.75 (NMS). Source: Nexqual, retrieved October 28, 2026 at 21:41 UTC.
Also available as compact Markdown for AI agents: nexqual.com/REPL.md
Key facts (REPL)
- Insider open-market sales, last ~7 months: 12 Form 4 filings, $1.6M; 11 not under a Rule 10b5-1 plan ($1.5M); 0 by opportunistic insiders, 7 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.00 on a 1–5 scale) (8 analysts), mean target USD 19.5 (range 14–24).
- Total return with dividends: 1Y +57.3% vs S&P 500 +13.6%; 5Y -45.6% vs S&P 500 +79.8%.
- Next earnings: 2026-10-28, EPS estimate USD -0.76, revenue estimate $6.7M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (REPL)
| USD | FY2022 | FY2023 | FY2024 | FY2025 | FY2026 | TTM |
|---|---|---|---|---|---|---|
| Operating income | -$118M | -$177M | -$235M | -$262M | -$320M | -$298M |
| Net income | -$118M | -$174M | -$216M | -$247M | -$314M | -$297M |
| EPS (diluted) | -$2.26 | -$2.99 | -$3.24 | -$3.07 | -$3.38 | — |
| Free cash flow | -$84.5M | -$130M | -$191M | -$199M | -$285M | -$281M |
| Cash + short-term investments | $396M | $583M | $421M | $484M | $269M | — |
| Total debt | $0K | $28.6M | $44.8M | $46.4M | $83.3M | — |
Fiscal years end Mar. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (REPL)
P/B 14.3x · FCF yield -18.54% · Earnings yield -19.63% · Net cash $111M · EV $1.40B
Insider sales (SEC Form 4, open-market, last ~7 months) (REPL)
1 of 12 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-08-17 | Hill Emily Luisa | Chief Financial Officer | 9,256 | $132K | 4.1% | No | Too little history (no open-market trades in 2023) |
| 2026-08-10 | Patel Sushil | Chief Executive Officer | 39,341 | $510K | 5.3% | No | Routine (sold in May each year 2023–2025; this trade is outside those months) |
| 2026-08-10 | Hill Emily Luisa | Chief Financial Officer | 11,448 | $148K | 4.8% | No | Too little history (no open-market trades in 2023) |
| 2026-08-10 | Xynos Konstantinos | Chief Medical Officer | 11,447 | $148K | 4.9% | No | Routine (sold in May & Nov each year 2023–2025; this trade is outside those months) |
| 2026-08-10 | Schwendenman Andrew | Chief Accounting Officer | 7,632 | $99K | 7.1% | No | Too little history (no open-market trades in 2023) |
| 2026-06-01 | Sarchi Christopher | Chief Commercial Officer | 12,000 | $111K | 6.2% | Yes (adopted December 15, 2025) | Routine (sold in Nov each year 2023–2025; this trade is outside those months) |
| 2026-05-18 | Xynos Konstantinos | Chief Medical Officer | 14,023 | $71K | 5.6% | No | Routine (sold in May & Nov each year 2023–2025) |
| 2026-05-18 | Schwendenman Andrew | Chief Accounting Officer | 7,894 | $40K | 6.9% | No | Too little history (no open-market trades in 2023) |
| 2026-05-18 | Sarchi Christopher | Chief Commercial Officer | 8,626 | $44K | 4.3% | No | Routine (sold in Nov each year 2023–2025; this trade is outside those months) |
| 2026-05-18 | Astley-Sparke Philip | Director | 17,657 | $90K | 1.2% | No | Routine (sold in May each year 2023–2025) |
| 2026-05-18 | Patel Sushil | Chief Executive Officer | 37,324 | $190K | 4.8% | No | Routine (sold in May each year 2023–2025) |
| 2026-05-18 | Hill Emily Luisa | Chief Financial Officer | 7,812 | $40K | 3.2% | No | Too little history (no open-market trades in 2023) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (REPL)
Consensus Buy (mean 2.00 on a 1–5 scale), 8 analysts; mean target USD 19.5 (low 14, high 24).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-08-26 | JP Morgan | Target raised | Overweight | $20 → $21 |
| 2026-08-07 | JP Morgan | Target raised | Overweight | $17 → $20 |
| 2026-08-07 | Wedbush | Upgrade | Neutral → Outperform | $12 → $19 |
| 2026-08-04 | Leerink Partners | Upgrade | Market Perform → Outperform | $11 → $17 |
| 2026-07-31 | Wedbush | Target raised | Neutral | $9 → $12 |
| 2026-07-31 | Cantor Fitzgerald | Upgrade | Neutral → Overweight |
Total return (dividends reinvested) (REPL)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +57.3% | -45.6% |
| S&P 500 (SPY) | +13.6% | +79.8% |
| Per year | +57.5% | -11.4% |
| Volatility (annualized) | 180.2% | 122.5% |
| Max drawdown | -84.2% (Dec 2025→Apr 2026) | -93.7% (Nov 2021→Apr 2026) |
REPL major shareholder filing: Schedule 13D/A, Aug 11, 2026
Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker filed a Schedule 13D/A with the SEC on Aug 11, 2026, reporting up to 11.80% of the class. A Schedule 13D is filed by an owner of more than 5% who may seek to influence the company. Item 4 (Purpose of Transaction), quoted from the filing:
Item 4 of Schedule 13D is supplemented and amended, as the case may be, as follows: The disclosures in Item 5 and Item 6 below are incorporated herein by reference. On August 9, 2026, Replimune Group, Inc. (the "Issuer") entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. (collectively, the "Underwriters"), related to the public offering (the "Offering") of 9,701,490 shares of common stock of the Issuer ("Common Stock") at a price to the public of $12.06 per share and 2,736,340 pre-funded warrants at a price to the public of $12.0599 per pre-funded warrant to purchase shares of Common Stock that are exercisable at any time on a 1-for-1 basis into Common Stock at an exercise price of $0.0001 per warrant with no expiration date, subject to beneficial ownership limitations described in Item 5 (the "2026 $0.0001 Prefunded Warrants"). The Offering closed on August 11, 2026. Pursuant to the Offering, 667 and Life Sciences purchased 126,394 and 2,609,946 2026 $0.0001 Prefunded Warrants, respectively, at the offering price of $12.0599 per pre-funded warrant, totaling 2,736,340 2026 $0.0001 Prefunded Warrants in the aggregate for an aggregate purchase price of $32,999,986.77. Each of 667 and Life Sciences purchased the 2026 $0.0001 Prefunded Warrants with its working capital. The Funds hold securities of the Issuer for investment purposes. …
Source: SEC EDGAR, Schedule 13D/A filed Aug 11, 2026. Quoted word for word; Nexqual adds no interpretation.
REPL earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 14, 2026 | Quarter ended Jun 30, 2026 | −$0.72 | −$0.77 | Beat +6.5% | -3.7% |
| Jun 29, 2026 | Quarter ended Mar 31, 2026 | −$0.76 | −$0.72 | Miss −5.6% | -4.8% |
| Feb 3, 2026 | Quarter ended Dec 31, 2025 | −$0.77 | −$0.82 | Beat +6.1% | +0.4% |
| Nov 6, 2025 | — | — | — | — | -3.1% |
| Aug 7, 2025 | — | — | — | — | -3.8% |
| May 22, 2025 | — | — | — | — | -1.3% |
| Feb 12, 2025 | — | — | — | — | +11.2% |
| Nov 12, 2024 | — | — | — | — | -6.5% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
REPL recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Oct 28, 2026 | 10-Q | Quarterly report · period ended Sep 30, 2026 |
| Oct 28, 2026 | 8-K | Quarterly results |
| Sep 16, 2026 | 8-K | Bylaws or fiscal-year change; Shareholder vote results |
| Aug 14, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 14, 2026 | Schedule 13G/A | Ridgeback Capital Investments L.P., Ridgeback Capital Investments LLC: 8.7% of shares, passive 5%+ holder (amended) |
| Aug 14, 2026 | 8-K | Quarterly results |
| Aug 11, 2026 | Schedule 13D/A | Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC: 11.8% of shares, 5%+ holder that may seek to influence the company (amended) “Item 4 of Schedule 13D is supplemented and amended, as the case may be, as follows: The disclosures in Item 5 and Item 6 below are incorporated herein by reference. On August 9, 2026, Replimune Group, Inc. (the "Issuer") entered into an underwriting agreement (the "Underwriting…” |
| Aug 11, 2026 | 8-K/A | Other material event “On August 9, 2026, the Company entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. (each, an "Underwriter" and, collectively, the "Underwriters"), relating to the issuance and sale of an aggregate of 9,701,490 shares of the Company's common stock (the "Shares") and pre-funded warrants to purchase 2,736,340 shares of the Company's common stock (the "Pre-Funded Warrants") to the Underwriters (the "Offering"). The…” |
| Aug 10, 2026 | Schedule 13G | THE GOLDMAN SACHS GROUP, INC., GOLDMAN SACHS & CO. LLC: 5.3% of shares, passive 5%+ holder |
| Aug 10, 2026 | 8-K | Other material event “On August 9, 2026, Replimune Group, Inc. (the "Company") entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. ("Cantor") (each, an "Underwriter" and, collectively, the "Underwriters"), relating to the issuance and sale of an aggregate of 9,701,490 shares of the Company's common stock (the "Shares") and pre-funded warrants to purchase 2,736,340 shares of the Company's common stock (the "Pre-Funded Warrants") to the…” |
| Aug 7, 2026 | Schedule 13G | STATE STREET CORPORATION: 5.3% of shares, passive 5%+ holder |
| Aug 7, 2026 | 8-K | Other material event “On August 6, 2026, Replimune Group, Inc. (the "Company") issued a press release announcing that the U.S. Food and Drug Administration has granted accelerated approval for TUDRIQEV TM (vusolimogene oderparepvec-wtpg), previously referred to as RP1, in combination with nivolumab for the treatment of adults with unresectable advanced cutaneous melanoma who experienced disease progression on an anti-PD-1 antibody-based regimen. Continued approval for this indication may be contingent upon verification and description…” |
| Aug 6, 2026 | Schedule 13G/A | Montanova Capital, LLC, Averill Master Fund, Ltd.: 7.9% of shares, passive 5%+ holder (amended) |
| Jul 31, 2026 | 8-K | Other material event |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
REPL suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | Hercules Capital, Inc. (HTGC) | “On October 6, 2022 we and certain of our subsidiaries entered into a Loan and Security Agreement, or the Hercules Loan Agreement with Hercules Capital, Inc., or Hercules, in its capacity as administrative agent and collateral agent and as a lender, which such agreement was subsequently amended in June 2023, December 2023 and January 2026.” |
Quoted from the company's 10-K filed Jun 29, 2026.
REPL analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Dec 2026) | $-0.76 | $-0.49 | −$0.27 | $6.7M | 2 |
| Next quarter (ends Mar 2027) | $-0.74 | $-0.44 | −$0.30 | $19.7M | 2 |
| Current fiscal year (ends Mar 2027) | $-3.01 | $-2.08 | −$0.92 | $28.9M | 2 |
| Next fiscal year (ends Mar 2028) | $-1.82 | $-1.10 | −$0.72 | $172.6M | 3 |
REPL options: expected move
Options price a move of about ±11.6% (±$1.53) by Oct 30, 2026, which includes earnings on Oct 28, 2026. Over the last 8 reports the stock moved ±4.4% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Oct 30, 2026 | 2 | 161.4% | ±11.6% |
| Nov 6, 2026 | 9 | 130.7% | ±17.2% |
| Nov 13, 2026 | 16 | 101.6% | ±17.4% |
| Nov 20, 2026 | 23 | 84.7% | ±17.2% |
| Nov 27, 2026 | 30 | 169.2% | ±38.5% |
| Dec 4, 2026 | 37 | 110.5% | ±28.1% |
| Dec 18, 2026 | 51 | 88.3% | ±26.1% |
| Jan 15, 2027 | 79 | 105.3% | ±38.4% |
30-day implied volatility 90.9% vs 84.4% realized over the last 30 trading days. Put/call ratio (volume) 0.55. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 28, 2026 at 21:41 UTC)
| Price | USD 16.06 |
|---|---|
| Change | ▲ 23.07% (up) |
| Previous Close | USD 13.05 |
| Open | USD 12.96 |
| Day Range | USD 12.5 – 16.75 |
| 52-Week Range | USD 1.5 – 16.75 |
| Volume | 7,277,843 shares |
| Market Cap | $1.51B |
| Exchange | NMS |
Technical Analysis (REPL)
Nexqual's technical model rates REPL "BUY" based on 5 bullish and 3 bearish signals across 127 daily candles, as of October 28, 2026 at 21:41 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 71.83 (overbought) |
| vs SMA50 | Above (USD 13.46) |
| MACD | 0.03 (positive) |
Analyst Ratings (REPL)
Wall Street analysts rate REPL "Buy" based on 8 analysts, with a mean price target of USD 19.5 (range USD 14–24), per Nexqual as of October 28, 2026 at 21:41 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 8 |
| Mean Target | USD 19.5 |
| High Target | USD 24 |
| Low Target | USD 14 |
| Buy / Hold / Sell | 7 / 0 / 1 |
Earnings (REPL)
| Next Earnings Date | 2026-10-28 |
|---|---|
| EPS Estimate | USD -0.76 |
| Revenue Estimate | $6.69M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-09-30 | USD -0.54 vs est -0.79 ▲ beat |
| 2026-06-30 | USD -0.72 vs est -0.77 ▲ beat |
| 2026-03-31 | USD -0.76 vs est -0.72 ▼ miss |
| 2025-12-31 | USD -0.77 vs est -0.82 ▲ beat |
Source: Nexqual, October 28, 2026 at 21:41 UTC.
Financials & Fundamentals (REPL)
| Gross Margin | +0.00% |
|---|---|
| Operating Margin | +0.00% |
| Profit Margin | +0.00% |
| ROE | -134.29% |
| Debt / Equity | 1.06 |
| Current Ratio | 5.23 |
| Total Cash | $195.33M |
| Total Debt | $111.97M |
Source: Nexqual, October 28, 2026 at 21:41 UTC.
Financial Health Score (REPL)
Nexqual rates Replimune Group, Inc.'s overall financial health "Weak" across five dimensions, as of October 28, 2026 at 21:41 UTC.
| Growth | Mixed — No data |
|---|---|
| Profitability | Weak — Pre-revenue or very early stage |
| Balance Sheet | Mixed — $195M cash and investments vs $84M debt (Jun 2026, SEC), net cash |
| Cash Flow | Weak — Operating cash flow -$280M (FY ended Mar 2026, 10-K) |
| Efficiency | Critical — ROE -281%, ROA -117.7% (last 4 quarters, SEC) |
Ownership (REPL)
| Insider Ownership | +1.65% |
|---|---|
| Institutional Ownership | +105.79% |
| Shares Outstanding | 94.22M |
| Float | 67.65M |
| Short % of Float | +34.30% |
Source: Nexqual, October 28, 2026 at 21:41 UTC.
Leadership (REPL)
Replimune Group, Inc. is led by Sushil Patel, CEO & Director, per Nexqual as of October 28, 2026 at 21:41 UTC.
| CEO & Director | Sushil Patel |
|---|---|
| Chief Financial Officer | Emily Luisa Hill |
| Executive Chairman | Philip Astley-Sparke F.S.A. |
| Senior Vice President of Quality Assurance | Carolyn Trott |
| Senior Vice President of Regulatory Affairs | Kari Jeschke |
Major Backers & Investors (REPL)
Notable institutional backers of Replimune Group, Inc. include Baker Bros. Advisors, LP, RTW Investments LP, Ridgeback Capital Investments L.P., according to Nexqual as of October 28, 2026 at 21:41 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Baker Bros. Advisors, LP | 11.78% |
| RTW Investments LP | 7.9% |
| Ridgeback Capital Investments L.P. | 7.79% |
| Goldman Sachs | 4.84% |
| Montanova Capital LLC | 4.68% |
| Boxer Capital Management, LLC | 4.25% |
| FCPM III Services B.V. | 2.99% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 9.55% |
| State Street | 4.73% |
| Vanguard Group | 3.09% |
Source: Nexqual, October 28, 2026 at 21:41 UTC.
From Replimune Group, Inc.'s Latest SEC 10-K Filing (filed 2026-06-29)
Key Strengths & Strategy (as disclosed to the SEC)
- We seek to protect our proprietary technology and processes, in part, by confidentiality agreements with our employees, consultants, scientific advisors and other contractors, as well as physical security of our premises and our information technology systems. management personnel, establishing clinical trial sites and patient registration for clinical trials, as well as in acquiring technologies and technology licenses complementary to our programs or advantageous to our business.
- In the United States, the FDA regulates biologics under the Federal Food, Drug, and Cosmetic Act, or FDCA, the Public Health Services Act, or PHSA, and their implementing regulations.
- Our proprietary oncolytic immunotherapy product candidates are designed and intended to maximally activate the immune system against cancer.
- Our proprietary RPx platform is based on a novel, engineered strain of herpes simplex virus 1, or HSV-1, backbone with payloads added that are intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response.
Partnerships
- In April 2019, we entered into a separate agreement with BMS on terms similar to the terms set forth in the agreement described above, pursuant to which BMS will provide, at no cost to us, nivolumab for use in our Phase 1 clinical trial of RP2 in combination with nivolumab.
- We continue our signal finding trial of RP2 in combination with atezolizumab and bevacizumab in the 2L setting of patients with hepatocellular carcinoma, or HCC, in collaboration with Roche.
Legal & Regulatory Risks (Item 1A, quoted)
- We are not permitted to market or promote or sell any of our product candidates before we receive regulatory approval from the FDA or comparable foreign regulatory authorities, and we may never receive such regulatory approval for any of our product candidates.
- Our ability to market, sell, distribute, obtain acceptable reimbursement for, set pricing for, and continue to operate and develop RP1 may be further delayed, adversely affected or prevented altogether.
- The regulatory approval processes of the FDA and comparable foreign regulatory authorities are lengthy, time consuming and inherently unpredictable. If we are not able to obtain, or experience delays in obtaining, required regulatory approvals, we will not be able to commercialize our product candidates as expected, and our ability to generate revenue may be materially impaired.
- The FDA or a comparable foreign regulatory authority may determine that our product candidates have undesirable side effects that could delay or prevent their regulatory approval or commercialization.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| ORKA | Oruka Therapeutics, Inc. | USD 95.97 | ▲ 0.17% |
| RYTM | Rhythm Pharmaceuticals, Inc. | USD 91.97 | ▼ 0.23% |
| IOVA | Iovance Biotherapeutics, Inc. | USD 14.81 | ▲ 1.58% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 44.9 | ▲ 2.14% |
| AXSM | Axsome Therapeutics, Inc. | USD 143.51 | ▲ 0.92% |
| PRAX | Praxis Precision Medicines, Inc | USD 285.48 | ▲ 6.69% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 28, 2026 at 21:41 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt