Replimune Group, Inc. (REPL) Stock Price & Analysis

Replimune Group, Inc. (REPL) closed at USD 16.06 on Wednesday, October 28, 2026, up 23.07% on the day. The US market is currently closed (after-hours); this is not a live price.

The prior close was USD 13.05; the Oct 28, 2026 session ranged USD 12.5–16.75 on volume of 7,277,843 shares. Market capitalization is $1.51B, with a 52-week range of USD 1.5–16.75 (NMS). Source: Nexqual, retrieved October 28, 2026 at 21:41 UTC.

Also available as compact Markdown for AI agents: nexqual.com/REPL.md

Key facts (REPL)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (REPL)

USDFY2022FY2023FY2024FY2025FY2026TTM
Operating income-$118M-$177M-$235M-$262M-$320M-$298M
Net income-$118M-$174M-$216M-$247M-$314M-$297M
EPS (diluted)-$2.26-$2.99-$3.24-$3.07-$3.38—
Free cash flow-$84.5M-$130M-$191M-$199M-$285M-$281M
Cash + short-term investments$396M$583M$421M$484M$269M—
Total debt$0K$28.6M$44.8M$46.4M$83.3M—

Fiscal years end Mar. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (REPL)

P/B 14.3x · FCF yield -18.54% · Earnings yield -19.63% · Net cash $111M · EV $1.40B

Insider sales (SEC Form 4, open-market, last ~7 months) (REPL)

1 of 12 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-08-17Hill Emily LuisaChief Financial Officer9,256$132K4.1%NoToo little history (no open-market trades in 2023)
2026-08-10Patel SushilChief Executive Officer39,341$510K5.3%NoRoutine (sold in May each year 2023–2025; this trade is outside those months)
2026-08-10Hill Emily LuisaChief Financial Officer11,448$148K4.8%NoToo little history (no open-market trades in 2023)
2026-08-10Xynos KonstantinosChief Medical Officer11,447$148K4.9%NoRoutine (sold in May & Nov each year 2023–2025; this trade is outside those months)
2026-08-10Schwendenman AndrewChief Accounting Officer7,632$99K7.1%NoToo little history (no open-market trades in 2023)
2026-06-01Sarchi ChristopherChief Commercial Officer12,000$111K6.2%Yes (adopted December 15, 2025)Routine (sold in Nov each year 2023–2025; this trade is outside those months)
2026-05-18Xynos KonstantinosChief Medical Officer14,023$71K5.6%NoRoutine (sold in May & Nov each year 2023–2025)
2026-05-18Schwendenman AndrewChief Accounting Officer7,894$40K6.9%NoToo little history (no open-market trades in 2023)
2026-05-18Sarchi ChristopherChief Commercial Officer8,626$44K4.3%NoRoutine (sold in Nov each year 2023–2025; this trade is outside those months)
2026-05-18Astley-Sparke PhilipDirector17,657$90K1.2%NoRoutine (sold in May each year 2023–2025)
2026-05-18Patel SushilChief Executive Officer37,324$190K4.8%NoRoutine (sold in May each year 2023–2025)
2026-05-18Hill Emily LuisaChief Financial Officer7,812$40K3.2%NoToo little history (no open-market trades in 2023)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (REPL)

Consensus Buy (mean 2.00 on a 1–5 scale), 8 analysts; mean target USD 19.5 (low 14, high 24).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-26JP MorganTarget raisedOverweight$20 → $21
2026-08-07JP MorganTarget raisedOverweight$17 → $20
2026-08-07WedbushUpgradeNeutral → Outperform$12 → $19
2026-08-04Leerink PartnersUpgradeMarket Perform → Outperform$11 → $17
2026-07-31WedbushTarget raisedNeutral$9 → $12
2026-07-31Cantor FitzgeraldUpgradeNeutral → Overweight

Total return (dividends reinvested) (REPL)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+57.3%-45.6%
S&P 500 (SPY)+13.6%+79.8%
Per year+57.5%-11.4%
Volatility (annualized)180.2%122.5%
Max drawdown-84.2% (Dec 2025→Apr 2026)-93.7% (Nov 2021→Apr 2026)

REPL major shareholder filing: Schedule 13D/A, Aug 11, 2026

Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker filed a Schedule 13D/A with the SEC on Aug 11, 2026, reporting up to 11.80% of the class. A Schedule 13D is filed by an owner of more than 5% who may seek to influence the company. Item 4 (Purpose of Transaction), quoted from the filing:

Item 4 of Schedule 13D is supplemented and amended, as the case may be, as follows: The disclosures in Item 5 and Item 6 below are incorporated herein by reference. On August 9, 2026, Replimune Group, Inc. (the "Issuer") entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. (collectively, the "Underwriters"), related to the public offering (the "Offering") of 9,701,490 shares of common stock of the Issuer ("Common Stock") at a price to the public of $12.06 per share and 2,736,340 pre-funded warrants at a price to the public of $12.0599 per pre-funded warrant to purchase shares of Common Stock that are exercisable at any time on a 1-for-1 basis into Common Stock at an exercise price of $0.0001 per warrant with no expiration date, subject to beneficial ownership limitations described in Item 5 (the "2026 $0.0001 Prefunded Warrants"). The Offering closed on August 11, 2026. Pursuant to the Offering, 667 and Life Sciences purchased 126,394 and 2,609,946 2026 $0.0001 Prefunded Warrants, respectively, at the offering price of $12.0599 per pre-funded warrant, totaling 2,736,340 2026 $0.0001 Prefunded Warrants in the aggregate for an aggregate purchase price of $32,999,986.77. Each of 667 and Life Sciences purchased the 2026 $0.0001 Prefunded Warrants with its working capital. The Funds hold securities of the Issuer for investment purposes. …

Source: SEC EDGAR, Schedule 13D/A filed Aug 11, 2026. Quoted word for word; Nexqual adds no interpretation.

REPL earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 14, 2026Quarter ended Jun 30, 2026−$0.72−$0.77Beat +6.5%-3.7%
Jun 29, 2026Quarter ended Mar 31, 2026−$0.76−$0.72Miss −5.6%-4.8%
Feb 3, 2026Quarter ended Dec 31, 2025−$0.77−$0.82Beat +6.1%+0.4%
Nov 6, 2025————-3.1%
Aug 7, 2025————-3.8%
May 22, 2025————-1.3%
Feb 12, 2025————+11.2%
Nov 12, 2024————-6.5%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

REPL recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 28, 202610-QQuarterly report · period ended Sep 30, 2026
Oct 28, 20268-KQuarterly results
Sep 16, 20268-KBylaws or fiscal-year change; Shareholder vote results
Aug 14, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 14, 2026Schedule 13G/ARidgeback Capital Investments L.P., Ridgeback Capital Investments LLC: 8.7% of shares, passive 5%+ holder (amended)
Aug 14, 20268-KQuarterly results
Aug 11, 2026Schedule 13D/ABaker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC: 11.8% of shares, 5%+ holder that may seek to influence the company (amended)
“Item 4 of Schedule 13D is supplemented and amended, as the case may be, as follows: The disclosures in Item 5 and Item 6 below are incorporated herein by reference. On August 9, 2026, Replimune Group, Inc. (the "Issuer") entered into an underwriting agreement (the "Underwriting…”
Aug 11, 20268-K/AOther material event
“On August 9, 2026, the Company entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. (each, an "Underwriter" and, collectively, the "Underwriters"), relating to the issuance and sale of an aggregate of 9,701,490 shares of the Company's common stock (the "Shares") and pre-funded warrants to purchase 2,736,340 shares of the Company's common stock (the "Pre-Funded Warrants") to the Underwriters (the "Offering"). The…”
Aug 10, 2026Schedule 13GTHE GOLDMAN SACHS GROUP, INC., GOLDMAN SACHS & CO. LLC: 5.3% of shares, passive 5%+ holder
Aug 10, 20268-KOther material event
“On August 9, 2026, Replimune Group, Inc. (the "Company") entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. ("Cantor") (each, an "Underwriter" and, collectively, the "Underwriters"), relating to the issuance and sale of an aggregate of 9,701,490 shares of the Company's common stock (the "Shares") and pre-funded warrants to purchase 2,736,340 shares of the Company's common stock (the "Pre-Funded Warrants") to the…”
Aug 7, 2026Schedule 13GSTATE STREET CORPORATION: 5.3% of shares, passive 5%+ holder
Aug 7, 20268-KOther material event
“On August 6, 2026, Replimune Group, Inc. (the "Company") issued a press release announcing that the U.S. Food and Drug Administration has granted accelerated approval for TUDRIQEV TM (vusolimogene oderparepvec-wtpg), previously referred to as RP1, in combination with nivolumab for the treatment of adults with unresectable advanced cutaneous melanoma who experienced disease progression on an anti-PD-1 antibody-based regimen. Continued approval for this indication may be contingent upon verification and description…”
Aug 6, 2026Schedule 13G/AMontanova Capital, LLC, Averill Master Fund, Ltd.: 7.9% of shares, passive 5%+ holder (amended)
Jul 31, 20268-KOther material event

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

REPL suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerHercules Capital, Inc. (HTGC)“On October 6, 2022 we and certain of our subsidiaries entered into a Loan and Security Agreement, or the Hercules Loan Agreement with Hercules Capital, Inc., or Hercules, in its capacity as administrative agent and collateral agent and as a lender, which such agreement was subsequently amended in June 2023, December 2023 and January 2026.”

Quoted from the company's 10-K filed Jun 29, 2026.

REPL analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Dec 2026)$-0.76$-0.49−$0.27$6.7M2
Next quarter (ends Mar 2027)$-0.74$-0.44−$0.30$19.7M2
Current fiscal year (ends Mar 2027)$-3.01$-2.08−$0.92$28.9M2
Next fiscal year (ends Mar 2028)$-1.82$-1.10−$0.72$172.6M3

REPL options: expected move

Options price a move of about ±11.6% (±$1.53) by Oct 30, 2026, which includes earnings on Oct 28, 2026. Over the last 8 reports the stock moved ±4.4% on average.

ExpirationDaysATM implied volatilityExpected move
Oct 30, 20262161.4%±11.6%
Nov 6, 20269130.7%±17.2%
Nov 13, 202616101.6%±17.4%
Nov 20, 20262384.7%±17.2%
Nov 27, 202630169.2%±38.5%
Dec 4, 202637110.5%±28.1%
Dec 18, 20265188.3%±26.1%
Jan 15, 202779105.3%±38.4%

30-day implied volatility 90.9% vs 84.4% realized over the last 30 trading days. Put/call ratio (volume) 0.55. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 28, 2026 at 21:41 UTC)

PriceUSD 16.06
Change▲ 23.07% (up)
Previous CloseUSD 13.05
OpenUSD 12.96
Day RangeUSD 12.5 – 16.75
52-Week RangeUSD 1.5 – 16.75
Volume7,277,843 shares
Market Cap$1.51B
ExchangeNMS

Technical Analysis (REPL)

Nexqual's technical model rates REPL "BUY" based on 5 bullish and 3 bearish signals across 127 daily candles, as of October 28, 2026 at 21:41 UTC.

Overall SignalBUY
RSI (14)71.83 (overbought)
vs SMA50Above (USD 13.46)
MACD0.03 (positive)

Analyst Ratings (REPL)

Wall Street analysts rate REPL "Buy" based on 8 analysts, with a mean price target of USD 19.5 (range USD 14–24), per Nexqual as of October 28, 2026 at 21:41 UTC.

Consensus RatingBuy
Analyst Count8
Mean TargetUSD 19.5
High TargetUSD 24
Low TargetUSD 14
Buy / Hold / Sell7 / 0 / 1

Earnings (REPL)

Next Earnings Date2026-10-28
EPS EstimateUSD -0.76
Revenue Estimate$6.69M

Recent Earnings History

QuarterActual vs Estimate
2026-09-30USD -0.54 vs est -0.79 ▲ beat
2026-06-30USD -0.72 vs est -0.77 ▲ beat
2026-03-31USD -0.76 vs est -0.72 ▼ miss
2025-12-31USD -0.77 vs est -0.82 ▲ beat

Source: Nexqual, October 28, 2026 at 21:41 UTC.

Financials & Fundamentals (REPL)

Gross Margin+0.00%
Operating Margin+0.00%
Profit Margin+0.00%
ROE-134.29%
Debt / Equity1.06
Current Ratio5.23
Total Cash$195.33M
Total Debt$111.97M

Source: Nexqual, October 28, 2026 at 21:41 UTC.

Financial Health Score (REPL)

Nexqual rates Replimune Group, Inc.'s overall financial health "Weak" across five dimensions, as of October 28, 2026 at 21:41 UTC.

GrowthMixed — No data
ProfitabilityWeak — Pre-revenue or very early stage
Balance SheetMixed — $195M cash and investments vs $84M debt (Jun 2026, SEC), net cash
Cash FlowWeak — Operating cash flow -$280M (FY ended Mar 2026, 10-K)
EfficiencyCritical — ROE -281%, ROA -117.7% (last 4 quarters, SEC)

Ownership (REPL)

Insider Ownership+1.65%
Institutional Ownership+105.79%
Shares Outstanding94.22M
Float67.65M
Short % of Float+34.30%

Source: Nexqual, October 28, 2026 at 21:41 UTC.

Leadership (REPL)

Replimune Group, Inc. is led by Sushil Patel, CEO & Director, per Nexqual as of October 28, 2026 at 21:41 UTC.

CEO & DirectorSushil Patel
Chief Financial OfficerEmily Luisa Hill
Executive ChairmanPhilip Astley-Sparke F.S.A.
Senior Vice President of Quality AssuranceCarolyn Trott
Senior Vice President of Regulatory AffairsKari Jeschke

Major Backers & Investors (REPL)

Notable institutional backers of Replimune Group, Inc. include Baker Bros. Advisors, LP, RTW Investments LP, Ridgeback Capital Investments L.P., according to Nexqual as of October 28, 2026 at 21:41 UTC.

Active Investors

InvestorStake
Baker Bros. Advisors, LP11.78%
RTW Investments LP7.9%
Ridgeback Capital Investments L.P.7.79%
Goldman Sachs4.84%
Montanova Capital LLC4.68%
Boxer Capital Management, LLC4.25%
FCPM III Services B.V.2.99%

Index Funds (Passive)

FundStake
BlackRock9.55%
State Street4.73%
Vanguard Group3.09%

Source: Nexqual, October 28, 2026 at 21:41 UTC.

From Replimune Group, Inc.'s Latest SEC 10-K Filing (filed 2026-06-29)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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IONSIonis Pharmaceuticals, Inc.USD 44.9▲ 2.14%
AXSMAxsome Therapeutics, Inc.USD 143.51▲ 0.92%
PRAXPraxis Precision Medicines, IncUSD 285.48▲ 6.69%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 28, 2026 at 21:41 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt