UroGen Pharma Ltd. (URGN) Stock Price & Analysis
UroGen Pharma Ltd. (URGN) closed at USD 33.75 on Wednesday, October 28, 2026, down 0.47% on the day. The US market is currently closed (pre-market); this is not a live price.
The prior close was USD 33.91; the Oct 28, 2026 session ranged USD 33.1–34.04 on volume of 1,587,964 shares. Market capitalization is $1.65B, with a 52-week range of USD 16.5–50.81 (NGM). Source: Nexqual, retrieved October 29, 2026 at 13:07 UTC.
Also available as compact Markdown for AI agents: nexqual.com/URGN.md
Key facts (URGN)
- Last four reported quarters (through Jun 30, 2026): revenue $189M, net income -$97.6M (-51.7% margin), free cash flow -$159M (SEC filings).
- 1 of 80 tracked superinvestors hold URGN (13F, Q2 2026): 1 new, 0 added, 0 reduced, 0 unchanged.
- Insider open-market sales, last ~7 months: 8 Form 4 filings, $4.2M; 5 not under a Rule 10b5-1 plan ($3.2M); 0 by opportunistic insiders, 7 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.00 on a 1–5 scale) (8 analysts), mean target USD 60 (range 48–75).
- Total return with dividends: 1Y +70.6% vs S&P 500 +13.6%; 5Y +96.2% vs S&P 500 +79.8%.
- Next earnings: 2026-11-04, EPS estimate USD 0.09, revenue estimate $89.8M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (URGN)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $48.0M | $64.4M | $82.7M | $90.4M | $110M | $189M |
| Gross profit | $42.9M | $56.7M | $73.4M | $81.5M | $97.3M | — |
| Operating income | -$92.3M | -$79.0M | -$65.5M | -$96.8M | -$125M | -$66.7M |
| Net income | -$111M | -$110M | -$102M | -$127M | -$153M | -$97.6M |
| EPS (diluted) | -$4.96 | — | — | — | — | — |
| Free cash flow | -$85.6M | -$87.8M | -$76.6M | -$97.1M | -$163M | -$159M |
| Gross margin | 89.3% | 88.1% | 88.7% | 90.2% | 88.7% | — |
| Operating margin | -192.1% | -122.8% | -79.2% | -107.1% | -113.7% | -35.3% |
| Net margin | -230.7% | -170.6% | -123.6% | -140.4% | -139.8% | -51.7% |
| Revenue growth | +307.2% | +34.0% | +28.5% | +9.3% | +21.4% | — |
| Cash + short-term investments | $66.9M | $100.0M | $142M | $242M | $121M | — |
| Total debt | $0K | $97.5M | $98.6M | $122M | $125M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (URGN)
P/S 8.7x · EV/Sales 9.2x · FCF yield -9.65% · Earnings yield -5.92% · Net debt $92.0M · EV $1.74B
Superinvestors (SEC 13F-HR, Q2 2026) (URGN)
1 of 80 tracked investors hold URGN. Each row is the investor's latest 13F; change is vs their prior-quarter share count.
| Investor | Firm | % of portfolio | Value | Change |
|---|---|---|---|---|
| Polen Capital | Polen Capital Management | 0.01% | $1.1M | New position |
Insider sales (SEC Form 4, open-market, last ~7 months) (URGN)
3 of 8 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-10-08 | Degnan Chris | Chief Financial Officer | 2,202 | $81K | 32.6% | No | Too little history (no open-market trades in 2023 or 2024) |
| 2026-09-08 | Schoenberg Mark | Chief Medical Officer | 871 | $37K | 1.4% | No | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
| 2026-09-08 | Smith Jason Drew | General Counsel | 1,519 | $65K | 2.8% | No | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
| 2026-08-20 | Schoenberg Mark | Chief Medical Officer | 60,677 | $2.9M | 50.7% | No | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
| 2026-07-09 | Schoenberg Mark | Chief Medical Officer | 10,000 | $400K | 7.7% | Yes | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
| 2026-06-22 | Schoenberg Mark | Chief Medical Officer | 10,000 | $350K | 7.2% | Yes | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
| 2026-06-08 | Schoenberg Mark | Chief Medical Officer | 5,222 | $143K | 3.6% | No | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
| 2026-05-08 | Schoenberg Mark | Chief Medical Officer | 10,000 | $300K | 6.9% | Yes | Routine (sold in Jan each year 2023–2025; this trade is outside those months) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (URGN)
Consensus Buy (mean 2.00 on a 1–5 scale), 8 analysts; mean target USD 60 (low 48, high 75).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-19 | HC Wainwright & Co. | Reiterated | Buy | $75 |
| 2026-08-06 | Guggenheim | Target raised | Buy | $42 → $58 |
| 2026-08-06 | HC Wainwright & Co. | Target raised | Buy | $45 → $75 |
| 2026-08-05 | TD Cowen | Target raised | Buy | $50 → $60 |
| 2026-07-21 | Guggenheim | Target raised | Buy | $32 → $42 |
| 2026-07-16 | Oppenheimer | Target raised | Outperform → Outperformer | $40 → $50 |
Total return (dividends reinvested) (URGN)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +70.6% | +96.2% |
| S&P 500 (SPY) | +13.6% | +79.8% |
| Per year | +70.9% | +14.4% |
| Volatility (annualized) | 61.9% | 87.5% |
| Max drawdown | -42.2% (Nov 2025→Mar 2026) | -81.5% (Jul 2023→May 2025) |
URGN earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 5, 2026 | Quarter ended Jun 30, 2026 | −$0.28 | −$0.26 | Miss −7.7% | +14.2% |
| May 6, 2026 | Quarter ended Mar 31, 2026 | −$0.47 | −$0.48 | Beat +2.1% | +11.6% |
| Mar 2, 2026 | Quarter ended Dec 31, 2025 | −$0.53 | −$0.51 | Miss −3.9% | -13.3% |
| Nov 6, 2025 | Quarter ended Sep 30, 2025 | −$0.69 | −$0.68 | Miss −1.5% | +20.4% |
| Aug 7, 2025 | — | — | — | — | -11.3% |
| May 12, 2025 | — | — | — | — | -2.3% |
| Mar 10, 2025 | — | — | — | — | +10.2% |
| Nov 6, 2024 | — | — | — | — | -0.9% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
URGN recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Oct 27, 2026 | Schedule 13G/A | BlackRock, Inc.: 6.3% of shares, passive 5%+ holder (amended) |
| Aug 20, 2026 | 8-K | Other material event “On August 18, 2026, UroGen Pharma Ltd. ("the Company"), through its wholly owned subsidiary UroGen Pharma, Inc. ("UroGen U.S."), entered into an Option and Research License Agreement (the "Option Agreement") with IntraGel Therapeutics, Ltd. ("IntraGel"), a company organized under the laws of Israel. Pursuant to the Option Agreement, UroGen U.S. obtained from IntraGel (i) an exclusive option to obtain an exclusive, worldwide license under certain intellectual property rights of IntraGel to develop, commercialize…” |
| Aug 12, 2026 | Schedule 13G/A | The Toronto-Dominion Bank, TD SECURITIES INC.: 6.9% of shares, passive 5%+ holder (amended) |
| Aug 5, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 5, 2026 | 8-K | Quarterly results |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
URGN suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Supplier | Isotopia Molecular Imaging | “We depend on Isotopia Molecular Imaging Ltd. as our single contracted suppliers for the hydrogel contained in Jelmyto and Zusduri.” |
| Supplier | Teva Pharmaceuticals | “We currently depend on Teva Pharmaceuticals Industries Ltd, as our single-source supplier of mitomycin API for Jelmyto, Zusduri, UGN-103 and UGN-104.” |
| Partner | AGENUS INC (AGEN) | “In November 2025, we decided to discontinue development of UGN-301 based on our strategic priorities and provided Agenus Inc. ("Agenus") notice of termination of the license agreement.” |
| Partner | Pharmakon Advisors | “On February 26, 2026, we entered into a second amended and restated loan agreement with Pharmakon providing for a senior secured term loan facility of up to $250.0 million, consisting of two tranches.” |
Quoted from the company's 10-K filed Mar 2, 2026.
Companies that name URGN in their SEC reports
| Relationship to URGN | Company | Filing | Sentence |
|---|---|---|---|
| partner | AGENUS INC (AGEN) | 10-K Mar 16, 2026 | “We have entered into collaborations with several companies, including Bristol-Myers Squibb Company ("BMS"), Betta Pharmaceuticals Co., Ltd. ("Betta"), UroGen Pharma Ltd. ("UroGen"), Gilead Sciences, Inc. ("Gilead"), Incyte Corporation ("Incyte"), and Merck Sharp & Dohme ("Merck").” |
URGN company outlook (results filed Aug 5, 2026)
- “Guidance: The Company continues to expect 2026 net product revenue for JELMYTO to be in the range of $97 million to $101 million.”
- “The Company is not providing full-year 2026 revenue guidance for ZUSDURI at this time, as the product remains in the early stages of its commercial launch.”
- “The Company is increasing its full-year 2026 operating expenses guidance to be in the range of $260 million to $270 million, including non-cash share-based compensation expense of $20 million to $24 million.”
Quoted word-for-word from the SEC 8-K results press release.
URGN analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $0.09 | $-0.05 | +$0.14 | $89.8M | 7 |
| Next quarter (ends Dec 2026) | $0.39 | $0.10 | +305.2% | $107.3M | 7 |
| Current fiscal year (ends Dec 2026) | $-0.24 | $-0.70 | +$0.46 | $320.5M | 7 |
| Next fiscal year (ends Dec 2027) | $2.59 | $1.49 | +73.2% | $522.8M | 7 |
URGN options: expected move
Options price a move of about ±20.4% (±$6.93) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±10.5% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 22 | 102.0% | ±20.4% |
| Dec 18, 2026 | 50 | 57.1% | ±17.1% |
| Jan 15, 2027 | 78 | 58.7% | ±21.8% |
| Feb 19, 2027 | 113 | 60.8% | ±26.9% |
| May 21, 2027 | 204 | 66.7% | ±39.1% |
30-day implied volatility 69.9% vs 41.6% realized over the last 30 trading days. Put/call ratio (volume) 0.08. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 29, 2026 at 13:07 UTC)
| Price | USD 33.75 |
|---|---|
| Change | ▼ 0.47% (down) |
| Previous Close | USD 33.91 |
| Open | USD 33.66 |
| Day Range | USD 33.1 – 34.04 |
| 52-Week Range | USD 16.5 – 50.81 |
| Volume | 1,587,964 shares |
| Market Cap | $1.65B |
| Exchange | NGM |
Technical Analysis (URGN)
Nexqual's technical model rates URGN "SELL" based on 2 bullish and 5 bearish signals across 127 daily candles, as of October 29, 2026 at 13:07 UTC.
| Overall Signal | SELL |
|---|---|
| RSI (14) | 29.2 (oversold) |
| vs SMA50 | Below (USD 41.06) |
| MACD | -2.09 (negative) |
Analyst Ratings (URGN)
Wall Street analysts rate URGN "Buy" based on 8 analysts, with a mean price target of USD 60 (range USD 48–75), per Nexqual as of October 29, 2026 at 13:07 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 8 |
| Mean Target | USD 60 |
| High Target | USD 75 |
| Low Target | USD 48 |
| Buy / Hold / Sell | 7 / 1 / 0 |
Earnings (URGN)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD 0.09 |
| Revenue Estimate | $89.83M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -0.28 vs est -0.27 ▼ miss |
| 2026-03-31 | USD -0.47 vs est -0.48 ▲ beat |
| 2025-12-31 | USD -0.53 vs est -0.51 ▼ miss |
| 2025-09-30 | USD -0.69 vs est -0.68 ▼ miss |
Source: Nexqual, October 29, 2026 at 13:07 UTC.
Financials & Fundamentals (URGN)
| Total Revenue | $188.73M |
|---|---|
| Revenue Growth (latest quarter, YoY) | +199.20% |
| Gross Margin | +90.84% |
| Operating Margin | +0.15% |
| Profit Margin | -51.73% |
| Current Ratio | 3.8 |
| Total Cash | $107.97M |
| Total Debt | $196.13M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$159.13M (-84.3% of revenue) |
Source: Nexqual, October 29, 2026 at 13:07 UTC.
Financial Health Score (URGN)
Nexqual rates UroGen Pharma Ltd.'s overall financial health "Mixed" across five dimensions, as of October 29, 2026 at 13:07 UTC.
| Growth | Strong — Revenue +21% YoY (annual) |
|---|---|
| Profitability | Solid — Gross margin 91%, operating -35% (last 4 quarters to Jun 2026, SEC) |
| Balance Sheet | Mixed — $108M cash and investments vs $200M debt (Jun 2026, SEC) |
| Cash Flow | Weak — FCF negative: -$159M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE not meaningful (negative equity); ROA -38.7% (last 4 quarters, SEC) |
Ownership (URGN)
| Insider Ownership | +3.49% |
|---|---|
| Institutional Ownership | +98.08% |
| Shares Outstanding | 48.88M |
| Float | 43.41M |
| Short % of Float | +11.70% |
Source: Nexqual, October 29, 2026 at 13:07 UTC.
Leadership (URGN)
UroGen Pharma Ltd. is led by Elizabeth A. Barrett, President, CEO & Director, per Nexqual as of October 29, 2026 at 13:07 UTC.
| President, CEO & Director | Elizabeth A. Barrett |
|---|---|
| Chief Financial Officer | Christopher Degnan |
| Senior Director of Investor Relations | Vincent I. Perrone |
| Senior Vice President of Human Resources | Alison Hardgrove |
| Executive Vice President of Research & Development and Technical Operations | Marina Konorty |
Major Backers & Investors (URGN)
Notable institutional backers of UroGen Pharma Ltd. include RTW Investments LP, Morgan Stanley, Kynam Capital Management, LP, according to Nexqual as of October 29, 2026 at 13:07 UTC.
Active Investors
| Investor | Stake |
|---|---|
| RTW Investments LP | 9.3% |
| Morgan Stanley | 5.27% |
| Kynam Capital Management, LP | 4.98% |
| Jefferies Financial Group Inc. | 4.5% |
| SG Americas Securities, LLC | 4.2% |
| American Century Companies Inc | 3.45% |
| Acorn Capital Advisors, LLC | 3.42% |
| Point72 Asset Management, L.P. | 3.12% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 6.55% |
Source: Nexqual, October 29, 2026 at 13:07 UTC.
From UroGen Pharma Ltd.'s Latest SEC 10-K Filing (filed 2026-03-02)
Key Strengths & Strategy (as disclosed to the SEC)
- In April 2024, we announced that the FDA accepted our Investigational New Drug Application ("IND") for UGN-103 and we initiated our Phase 3 UTOPIA trial, a single-arm, multicenter study evaluating the efficacy and safety of UGN-103 in patients with recurrent low-grade intermediate risk NMIBC.
- We have developed RTGel reverse-thermal hydrogel, a proprietary sustained release, hydrogel-based technology that has the potential to improve therapeutic profiles of existing drugs.
- Jelmyto consists of mitomycin, an established chemotherapy, and sterile hydrogel, using our proprietary sustained release RTGel technology.
- Zusduri, which consists of mitomycin and sterile hydrogel, uses our proprietary sustained release RTGel technology and is delivered directly into the bladder in an out-patient procedure by a trained healthcare professional using a urinary catheter to enable the treatment of tumors by non-surgical means.
Partnerships
- In November 2025, we provided notice to terminate the license agreement with Agenus in connection with our decision to discontinue development of UGN-301.
Legal & Regulatory Risks (Item 1A, quoted)
- Our product candidates may not receive the requisite approvals for commercialization, or we may need to conduct additional nonclinical experiments and clinical trials, provide additional data and information, and meet additional standards for regulatory approval.
- We expect current and future legislation affecting the healthcare industry, including healthcare reform, to impact our business generally and to increase limitations on reimbursement, rebates and other payments, which could adversely affect third-party coverage of our products, our operations, and/or how much or under what circumstances healthcare providers will prescribe or administer our products, if approved.
- The United States and some foreign jurisdictions are considering or have enacted a number of legislative and regulatory proposals to change the healthcare system in ways that could affect our ability to sell our products profitably.
- We may be unable to obtain Orphan Drug Designation or exclusivity for future product candidates we may develop.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| RYTM | Rhythm Pharmaceuticals, Inc. | USD 91.97 | ▼ 0.23% |
| LGND | Ligand Pharmaceuticals Incorpor | USD 318.78 | ▲ 2.26% |
| IOVA | Iovance Biotherapeutics, Inc. | USD 14.81 | ▲ 1.58% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 44.9 | ▲ 2.14% |
| AXSM | Axsome Therapeutics, Inc. | USD 143.51 | ▲ 0.92% |
| ABVX | Abivax SA | USD 89.84 | ▲ 3.26% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 13:07 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt