Acadia Pharmaceuticals Inc. (ACAD) Stock Price & Analysis

Acadia Pharmaceuticals Inc. (ACAD) is trading at USD 20.76, up 2.14% today, as of October 29, 2026 at 19:40 UTC (US market open; quotes may be delayed), according to Nexqual market data.

ACAD last closed at USD 20.32; today's session has ranged USD 20.5–20.77 on volume of 798,570 shares. Market capitalization is $3.58B, with a 52-week range of USD 18.39–30.96 (NMS). Source: Nexqual, retrieved October 29, 2026 at 19:40 UTC.

Also available as compact Markdown for AI agents: nexqual.com/ACAD.md

Key facts (ACAD)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (ACAD)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$484M$517M$726M$958M$1.07B$1.14B
Gross profit$473M$507M$685M$876M$983M—
Operating income-$170M-$224M-$73.4M$231M$105M$86.4M
Net income-$168M-$216M-$61.3M$226M$391M$380M
EPS (diluted)-$1.05-$1.34-$0.37$1.36$2.30—
Free cash flow-$127M-$114M$16.7M$157M$105M$146M
Gross margin97.8%98.0%94.3%91.5%91.7%—
Operating margin-35.2%-43.2%-10.1%24.1%9.8%7.6%
Net margin-34.7%-41.8%-8.4%23.6%36.5%33.4%
Revenue growth+9.6%+6.8%+40.4%+31.8%+11.9%—
Cash + short-term investments$521M$417M$439M$756M$820M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (ACAD)

P/E 9.4x · P/S 3.1x · P/FCF 24.5x · P/B 2.7x · FCF yield 4.07% · Earnings yield 10.64%

P/E at fiscal year-ends: Dec 2025 11.6x, Dec 2024 13.5x.

Insider sales (SEC Form 4, open-market, last ~7 months) (ACAD)

5 of 6 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-08-05…2026-08-06Schneyer Mark C.EVP, CHIEF FINANCIAL OFFICER20,141$587K22.9%Yes (adopted May 19, 2025)Routine (sold in Feb & Apr & May & Aug & Nov each year 2023–2025)
2026-07-30Thompson Elizabeth H.Z.EVP, Head of Research & Dev16,558$433K46.6%YesToo little history (no open-market trades in 2023–2025)
2026-06-26Kihara JamesPRINCIPAL ACCOUNTING OFFICER11,421$298K46.6%Yes (adopted December 9, 2025)Routine (sold in Feb & Apr & May & Nov each year 2023–2025; this trade is outside those months)
2026-05-26Kihara JamesPRINCIPAL ACCOUNTING OFFICER5,401$114K18.1%NoRoutine (sold in Feb & Apr & May & Nov each year 2023–2025)
2026-05-04Kihara JamesPRINCIPAL ACCOUNTING OFFICER1,332$29K4.4%YesRoutine (sold in Feb & Apr & May & Nov each year 2023–2025)
2026-05-04Schneyer Mark C.EVP, CHIEF FINANCIAL OFFICER3,506$76K5%YesRoutine (sold in Feb & Apr & May & Aug & Nov each year 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (ACAD)

Consensus Buy (mean 2.15 on a 1–5 scale), 20 analysts; mean target USD 30.53 (low 16, high 37).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-19NeedhamReiteratedBuy$35
2026-10-13UBSDowngradeBuy → Neutral$49 → $23
2026-10-08RBC CapitalTarget loweredOutperform$37 → $36
2026-09-25Deutsche BankTarget loweredBuy$38 → $31
2026-09-25HC Wainwright & Co.Target loweredBuy$37 → $33
2026-09-25CitizensTarget loweredMarket Outperform$36 → $33
2026-09-25BMO CapitalTarget loweredOutperform$36 → $34
2026-09-25NeedhamTarget loweredBuy$41 → $35
2026-09-24CitigroupTarget loweredBuy$40 → $33
2026-09-24NeedhamReiteratedBuy$41
2026-08-25Deutsche BankTarget raisedBuy$37 → $38
2026-08-25Morgan StanleyTarget raisedEqual-Weight$27 → $28

Total return (dividends reinvested) (ACAD)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return-7.9%+15.6%
S&P 500 (SPY)+12.9%+78.8%
Per year-7.9%+2.9%
Volatility (annualized)39.0%49.9%
Max drawdown-39.1% (Aug 2026→Oct 2026)-55.4% (Jul 2023→Oct 2024)

ACAD earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 4, 2026Quarter ended Jun 30, 2026$0.18$0.04Beat +$0.14+12.5%
May 6, 2026Quarter ended Mar 31, 2026$0.02$0.08Miss −75.0%+0.9%
Feb 25, 2026Quarter ended Dec 31, 2025$0.14$0.14In line+0.2%
Jan 13, 2026Quarter ended Dec 31, 2025$0.14$0.14In line+1.0%
Nov 5, 2025Quarter ended Sep 30, 2025$0.42$0.15Beat +180.0%-0.9%
Aug 6, 2025————+3.2%
May 7, 2025————+16.4%
Feb 26, 2025————+1.7%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

ACAD recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 23, 20268-KDirector or executive officer change, or pay arrangement
Sep 24, 20268-KRegulation FD disclosure; Other material event
“On September 24, 2026, the Company announced Phase 3 enabling topline results from the Phase 2 portion of the ongoing RADIANT clinical trial program evaluating remlifanserin for the treatment of hallucinations and delusions associated with ADP. For the primary endpoint of change from baseline in the Scale for the Assessment of Positive Symptoms-Hallucinations and Delusions subscales (SAPS-H+D), once daily 60 mg remlifanserin demonstrated a change of -12.6 versus a -10.4 change for placebo at week 6, yielding a…”
Sep 11, 20268-KOther material event
“On August 24, 2026, the United States District Court for the Southern District of California (the "Court") preliminarily approved the settlement ("Settlement") of the stockholder derivative action captioned Kanner et al. v. Biggar et al. , Case No. 3:23-cv-02293-WQH-MSB. Pursuant to the Court's order granting preliminary approval of the Settlement, Acadia Pharmaceuticals Inc. (the "Company") is required to publish the Notice of Pendency and Proposed Settlement of Derivative Matters (the "Notice"), attached hereto…”
Aug 7, 2026Schedule 13GSTATE STREET CORPORATION: 5.3% of shares, passive 5%+ holder
Aug 5, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 4, 20268-KQuarterly results

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

ACAD revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Nuplazid$183.1M59.5%+8.7%
Daybue$124.8M40.5%+29.9%
Total revenue$308.0M100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

ACAD suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
SupplierGeneral“General business and economic conditions that could affect our business, financial condition or results of operations include fluctuations in economic growth, debt and equity capital markets, liquidity of the global financial markets, the availability and cost of credit, investor and consumer confidence, and the strength of the economies in which we, our collaborators, our manufacturers and our suppliers operate.”
PartnerNeuren Pharmaceuticals“In July 2023, we expanded the 2018 licensing agreement with Neuren to acquire rights to trofinetide outside of North America as well as global rights to Neuren's development candidate NNZ-2591 in Rett syndrome and Fragile X syndrome.”
PartnerStoke Therapeutics, Inc. (STOK)“In January 2022, we entered into a license and collaboration with Stoke Therapeutics, Inc. (Stoke) to discover, develop and commercialize novel RNA-based medicines for the potential treatment of severe and rare genetic neurodevelopmental diseases of the central nervous system (CNS).”
PartnerPatheon Pharmaceuticals“Under the manufacturing agreement with Patheon, we have agreed to purchase from Patheon a specified percentage of our commercial requirements of NUPLAZID for the United States.”
PartnerSiegfried“Under the manufacturing agreement with Siegfried, Acadia GmbH has agreed to purchase specified percentages of our commercial requirements of the pimavanserin API at a predefined price.”
PartnerCatalent Pharma Solutions“Under the manufacturing agreement with Catalent, we have agreed to purchase from Catalent NUPLAZID for commercial use in the United States.”
PartnerCorden Pharma Bergamo“Under the manufacturing agreement with Corden, we have agreed to purchase from Corden the API for trofinetide products at specified price per volume and a specified percentage of our commercial requirements of trofinetide API for the United States and Canada market.”
PartnerHalo Pharmaceuticals“Under the manufacturing agreement with Halo, we have agreed to purchase from Halo a specified number of bathes of our commercial requirements of DAYBUE STIX for the United States.”

Quoted from the company's 10-K filed Feb 26, 2026.

Companies that name ACAD in their SEC reports

Relationship to ACADCompanyFilingSentence
partnerStoke Therapeutics, Inc. (STOK)10-K Mar 16, 2026“the success of our collaborations with Acadia Pharmaceuticals and Biogen and our ability to enter into successful collaborations in the future;”

ACAD analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$0.18$0.13+40.7%$332.6M14
Next quarter (ends Dec 2026)$0.21$0.17+21.9%$361.6M13
Current fiscal year (ends Dec 2026)$0.60$0.37+62.3%$1.27B14
Next fiscal year (ends Dec 2027)$0.92$0.85+7.7%$1.43B13

ACAD options: expected move

Options price a move of about ±9.6% (±$1.95) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±4.6% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262252.9%±9.6%
Dec 18, 20265035.2%±13.1%
Jan 15, 20277831.9%±16.3%
Mar 19, 202714129.7%±18.0%
Jun 17, 202723147.3%±29.6%

30-day implied volatility 41.9% vs 53.9% realized over the last 30 trading days. Put/call ratio (volume) 4.08. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 19:40 UTC)

PriceUSD 20.76
Change▲ 2.14% (up)
Previous CloseUSD 20.32
OpenUSD 20.61
Day RangeUSD 20.5 – 20.77
52-Week RangeUSD 18.39 – 30.96
Volume798,570 shares
Market Cap$3.58B
ExchangeNMS

Technical Analysis (ACAD)

Nexqual's technical model rates ACAD "SELL" based on 2 bullish and 4 bearish signals across 128 daily candles, as of October 29, 2026 at 19:40 UTC.

Overall SignalSELL
RSI (14)42.21 (neutral)
vs SMA50Below (USD 23.91)
MACD-0.84 (negative)

Analyst Ratings (ACAD)

Wall Street analysts rate ACAD "Buy" based on 20 analysts, with a mean price target of USD 30.53 (range USD 16–37), per Nexqual as of October 29, 2026 at 19:40 UTC.

Consensus RatingBuy
Analyst Count20
Mean TargetUSD 30.53
High TargetUSD 37
Low TargetUSD 16
Buy / Hold / Sell14 / 5 / 1

Earnings (ACAD)

Next Earnings Date2026-11-04
EPS EstimateUSD 0.18
Revenue Estimate$332.55M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 0.18 vs est 0.04 ▲ beat
2026-03-31USD 0.02 vs est 0.08 ▼ miss
2025-12-31USD 0.14 vs est 0.14 ▼ miss
2025-09-30USD 0.42 vs est 0.15 ▲ beat

Source: Nexqual, October 29, 2026 at 19:40 UTC.

Financials & Fundamentals (ACAD)

Total Revenue$1.14B
Revenue Growth (latest quarter, YoY)+16.40%
Gross Margin+62.06%
Operating Margin+12.29%
Profit Margin+33.42%
ROE+35.74%
Debt / Equity0.06
Current Ratio3.39
Total Cash$956.47M
Total Debt$73.85M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)$145.63M (12.8% of revenue)

Source: Nexqual, October 29, 2026 at 19:40 UTC.

Financial Health Score (ACAD)

Nexqual rates Acadia Pharmaceuticals Inc.'s overall financial health "Strong" across five dimensions, as of October 29, 2026 at 19:40 UTC.

GrowthSolid — Revenue +12% YoY (annual)
ProfitabilityStrong — Gross margin 91%, operating 8% (last 4 quarters to Jun 2026, SEC)
Balance SheetStrong — $956M cash vs $74M debt, net cash position
Cash FlowSolid — FCF $146M (last 4 quarters to Jun 2026, SEC), 13% margin
EfficiencyStrong — ROE 29%, ROA 21.8% (last 4 quarters, SEC)

Ownership (ACAD)

Insider Ownership+0.33%
Institutional Ownership+100.05%
Shares Outstanding172.31M
Float128.35M
Short % of Float+8.34%

Source: Nexqual, October 29, 2026 at 19:40 UTC.

Leadership (ACAD)

Acadia Pharmaceuticals Inc. is led by Catherine E. Owen Adams, CEO & Director, per Nexqual as of October 29, 2026 at 19:40 UTC.

CEO & DirectorCatherine E. Owen Adams
Executive VP & CFOMark C. Schneyer

Major Backers & Investors (ACAD)

Notable institutional backers of Acadia Pharmaceuticals Inc. include Baker Bros. Advisors, LP, RTW Investments LP, Palo Alto Investors Lp, according to Nexqual as of October 29, 2026 at 19:40 UTC.

Active Investors

InvestorStake
Baker Bros. Advisors, LP24.91%
RTW Investments LP4.15%
Palo Alto Investors Lp1.66%
Goldman Sachs1.5%
Fidelity0.82%

Index Funds (Passive)

FundStake
BlackRock13.07%
Vanguard Group8.48%
State Street5.27%
Dimensional Fund Advisors2.14%
Geode Capital1.95%

Source: Nexqual, October 29, 2026 at 19:40 UTC.

From Acadia Pharmaceuticals Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 19:40 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt