Acadia Pharmaceuticals Inc. (ACAD) Stock Price & Analysis
Acadia Pharmaceuticals Inc. (ACAD) is trading at USD 20.76, up 2.14% today, as of October 29, 2026 at 19:40 UTC (US market open; quotes may be delayed), according to Nexqual market data.
ACAD last closed at USD 20.32; today's session has ranged USD 20.5–20.77 on volume of 798,570 shares. Market capitalization is $3.58B, with a 52-week range of USD 18.39–30.96 (NMS). Source: Nexqual, retrieved October 29, 2026 at 19:40 UTC.
Also available as compact Markdown for AI agents: nexqual.com/ACAD.md
Key facts (ACAD)
- Last four reported quarters (through Jun 30, 2026): revenue $1.14B, net income $380M (33.4% margin), free cash flow $146M (SEC filings).
- Valuation: P/E 9.4x (avg 12.6x at the last 2 fiscal year-ends).
- Insider open-market sales, last ~7 months: 6 Form 4 filings, $1.5M; 1 not under a Rule 10b5-1 plan ($114K); 0 by opportunistic insiders, 5 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.15 on a 1–5 scale) (20 analysts), mean target USD 30.53 (range 16–37).
- Total return with dividends: 1Y -7.9% vs S&P 500 +12.9%; 5Y +15.6% vs S&P 500 +78.8%.
- Next earnings: 2026-11-04, EPS estimate USD 0.18, revenue estimate $333M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (ACAD)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $484M | $517M | $726M | $958M | $1.07B | $1.14B |
| Gross profit | $473M | $507M | $685M | $876M | $983M | — |
| Operating income | -$170M | -$224M | -$73.4M | $231M | $105M | $86.4M |
| Net income | -$168M | -$216M | -$61.3M | $226M | $391M | $380M |
| EPS (diluted) | -$1.05 | -$1.34 | -$0.37 | $1.36 | $2.30 | — |
| Free cash flow | -$127M | -$114M | $16.7M | $157M | $105M | $146M |
| Gross margin | 97.8% | 98.0% | 94.3% | 91.5% | 91.7% | — |
| Operating margin | -35.2% | -43.2% | -10.1% | 24.1% | 9.8% | 7.6% |
| Net margin | -34.7% | -41.8% | -8.4% | 23.6% | 36.5% | 33.4% |
| Revenue growth | +9.6% | +6.8% | +40.4% | +31.8% | +11.9% | — |
| Cash + short-term investments | $521M | $417M | $439M | $756M | $820M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (ACAD)
P/E 9.4x · P/S 3.1x · P/FCF 24.5x · P/B 2.7x · FCF yield 4.07% · Earnings yield 10.64%
P/E at fiscal year-ends: Dec 2025 11.6x, Dec 2024 13.5x.
Insider sales (SEC Form 4, open-market, last ~7 months) (ACAD)
5 of 6 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-08-05…2026-08-06 | Schneyer Mark C. | EVP, CHIEF FINANCIAL OFFICER | 20,141 | $587K | 22.9% | Yes (adopted May 19, 2025) | Routine (sold in Feb & Apr & May & Aug & Nov each year 2023–2025) |
| 2026-07-30 | Thompson Elizabeth H.Z. | EVP, Head of Research & Dev | 16,558 | $433K | 46.6% | Yes | Too little history (no open-market trades in 2023–2025) |
| 2026-06-26 | Kihara James | PRINCIPAL ACCOUNTING OFFICER | 11,421 | $298K | 46.6% | Yes (adopted December 9, 2025) | Routine (sold in Feb & Apr & May & Nov each year 2023–2025; this trade is outside those months) |
| 2026-05-26 | Kihara James | PRINCIPAL ACCOUNTING OFFICER | 5,401 | $114K | 18.1% | No | Routine (sold in Feb & Apr & May & Nov each year 2023–2025) |
| 2026-05-04 | Kihara James | PRINCIPAL ACCOUNTING OFFICER | 1,332 | $29K | 4.4% | Yes | Routine (sold in Feb & Apr & May & Nov each year 2023–2025) |
| 2026-05-04 | Schneyer Mark C. | EVP, CHIEF FINANCIAL OFFICER | 3,506 | $76K | 5% | Yes | Routine (sold in Feb & Apr & May & Aug & Nov each year 2023–2025) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (ACAD)
Consensus Buy (mean 2.15 on a 1–5 scale), 20 analysts; mean target USD 30.53 (low 16, high 37).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-19 | Needham | Reiterated | Buy | $35 |
| 2026-10-13 | UBS | Downgrade | Buy → Neutral | $49 → $23 |
| 2026-10-08 | RBC Capital | Target lowered | Outperform | $37 → $36 |
| 2026-09-25 | Deutsche Bank | Target lowered | Buy | $38 → $31 |
| 2026-09-25 | HC Wainwright & Co. | Target lowered | Buy | $37 → $33 |
| 2026-09-25 | Citizens | Target lowered | Market Outperform | $36 → $33 |
| 2026-09-25 | BMO Capital | Target lowered | Outperform | $36 → $34 |
| 2026-09-25 | Needham | Target lowered | Buy | $41 → $35 |
| 2026-09-24 | Citigroup | Target lowered | Buy | $40 → $33 |
| 2026-09-24 | Needham | Reiterated | Buy | $41 |
| 2026-08-25 | Deutsche Bank | Target raised | Buy | $37 → $38 |
| 2026-08-25 | Morgan Stanley | Target raised | Equal-Weight | $27 → $28 |
Total return (dividends reinvested) (ACAD)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | -7.9% | +15.6% |
| S&P 500 (SPY) | +12.9% | +78.8% |
| Per year | -7.9% | +2.9% |
| Volatility (annualized) | 39.0% | 49.9% |
| Max drawdown | -39.1% (Aug 2026→Oct 2026) | -55.4% (Jul 2023→Oct 2024) |
ACAD earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 4, 2026 | Quarter ended Jun 30, 2026 | $0.18 | $0.04 | Beat +$0.14 | +12.5% |
| May 6, 2026 | Quarter ended Mar 31, 2026 | $0.02 | $0.08 | Miss −75.0% | +0.9% |
| Feb 25, 2026 | Quarter ended Dec 31, 2025 | $0.14 | $0.14 | In line | +0.2% |
| Jan 13, 2026 | Quarter ended Dec 31, 2025 | $0.14 | $0.14 | In line | +1.0% |
| Nov 5, 2025 | Quarter ended Sep 30, 2025 | $0.42 | $0.15 | Beat +180.0% | -0.9% |
| Aug 6, 2025 | — | — | — | — | +3.2% |
| May 7, 2025 | — | — | — | — | +16.4% |
| Feb 26, 2025 | — | — | — | — | +1.7% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
ACAD recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Oct 23, 2026 | 8-K | Director or executive officer change, or pay arrangement |
| Sep 24, 2026 | 8-K | Regulation FD disclosure; Other material event “On September 24, 2026, the Company announced Phase 3 enabling topline results from the Phase 2 portion of the ongoing RADIANT clinical trial program evaluating remlifanserin for the treatment of hallucinations and delusions associated with ADP. For the primary endpoint of change from baseline in the Scale for the Assessment of Positive Symptoms-Hallucinations and Delusions subscales (SAPS-H+D), once daily 60 mg remlifanserin demonstrated a change of -12.6 versus a -10.4 change for placebo at week 6, yielding a…” |
| Sep 11, 2026 | 8-K | Other material event “On August 24, 2026, the United States District Court for the Southern District of California (the "Court") preliminarily approved the settlement ("Settlement") of the stockholder derivative action captioned Kanner et al. v. Biggar et al. , Case No. 3:23-cv-02293-WQH-MSB. Pursuant to the Court's order granting preliminary approval of the Settlement, Acadia Pharmaceuticals Inc. (the "Company") is required to publish the Notice of Pendency and Proposed Settlement of Derivative Matters (the "Notice"), attached hereto…” |
| Aug 7, 2026 | Schedule 13G | STATE STREET CORPORATION: 5.3% of shares, passive 5%+ holder |
| Aug 5, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 4, 2026 | 8-K | Quarterly results |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
ACAD revenue by product line (quarter ended Jun 30, 2026)
| Line | Revenue | Share of total | YoY |
|---|---|---|---|
| Nuplazid | $183.1M | 59.5% | +8.7% |
| Daybue | $124.8M | 40.5% | +29.9% |
| Total revenue | $308.0M | 100% | — |
As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).
ACAD suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Supplier | General | “General business and economic conditions that could affect our business, financial condition or results of operations include fluctuations in economic growth, debt and equity capital markets, liquidity of the global financial markets, the availability and cost of credit, investor and consumer confidence, and the strength of the economies in which we, our collaborators, our manufacturers and our suppliers operate.” |
| Partner | Neuren Pharmaceuticals | “In July 2023, we expanded the 2018 licensing agreement with Neuren to acquire rights to trofinetide outside of North America as well as global rights to Neuren's development candidate NNZ-2591 in Rett syndrome and Fragile X syndrome.” |
| Partner | Stoke Therapeutics, Inc. (STOK) | “In January 2022, we entered into a license and collaboration with Stoke Therapeutics, Inc. (Stoke) to discover, develop and commercialize novel RNA-based medicines for the potential treatment of severe and rare genetic neurodevelopmental diseases of the central nervous system (CNS).” |
| Partner | Patheon Pharmaceuticals | “Under the manufacturing agreement with Patheon, we have agreed to purchase from Patheon a specified percentage of our commercial requirements of NUPLAZID for the United States.” |
| Partner | Siegfried | “Under the manufacturing agreement with Siegfried, Acadia GmbH has agreed to purchase specified percentages of our commercial requirements of the pimavanserin API at a predefined price.” |
| Partner | Catalent Pharma Solutions | “Under the manufacturing agreement with Catalent, we have agreed to purchase from Catalent NUPLAZID for commercial use in the United States.” |
| Partner | Corden Pharma Bergamo | “Under the manufacturing agreement with Corden, we have agreed to purchase from Corden the API for trofinetide products at specified price per volume and a specified percentage of our commercial requirements of trofinetide API for the United States and Canada market.” |
| Partner | Halo Pharmaceuticals | “Under the manufacturing agreement with Halo, we have agreed to purchase from Halo a specified number of bathes of our commercial requirements of DAYBUE STIX for the United States.” |
Quoted from the company's 10-K filed Feb 26, 2026.
Companies that name ACAD in their SEC reports
| Relationship to ACAD | Company | Filing | Sentence |
|---|---|---|---|
| partner | Stoke Therapeutics, Inc. (STOK) | 10-K Mar 16, 2026 | “the success of our collaborations with Acadia Pharmaceuticals and Biogen and our ability to enter into successful collaborations in the future;” |
ACAD analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $0.18 | $0.13 | +40.7% | $332.6M | 14 |
| Next quarter (ends Dec 2026) | $0.21 | $0.17 | +21.9% | $361.6M | 13 |
| Current fiscal year (ends Dec 2026) | $0.60 | $0.37 | +62.3% | $1.27B | 14 |
| Next fiscal year (ends Dec 2027) | $0.92 | $0.85 | +7.7% | $1.43B | 13 |
ACAD options: expected move
Options price a move of about ±9.6% (±$1.95) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±4.6% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 22 | 52.9% | ±9.6% |
| Dec 18, 2026 | 50 | 35.2% | ±13.1% |
| Jan 15, 2027 | 78 | 31.9% | ±16.3% |
| Mar 19, 2027 | 141 | 29.7% | ±18.0% |
| Jun 17, 2027 | 231 | 47.3% | ±29.6% |
30-day implied volatility 41.9% vs 53.9% realized over the last 30 trading days. Put/call ratio (volume) 4.08. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 29, 2026 at 19:40 UTC)
| Price | USD 20.76 |
|---|---|
| Change | ▲ 2.14% (up) |
| Previous Close | USD 20.32 |
| Open | USD 20.61 |
| Day Range | USD 20.5 – 20.77 |
| 52-Week Range | USD 18.39 – 30.96 |
| Volume | 798,570 shares |
| Market Cap | $3.58B |
| Exchange | NMS |
Technical Analysis (ACAD)
Nexqual's technical model rates ACAD "SELL" based on 2 bullish and 4 bearish signals across 128 daily candles, as of October 29, 2026 at 19:40 UTC.
| Overall Signal | SELL |
|---|---|
| RSI (14) | 42.21 (neutral) |
| vs SMA50 | Below (USD 23.91) |
| MACD | -0.84 (negative) |
Analyst Ratings (ACAD)
Wall Street analysts rate ACAD "Buy" based on 20 analysts, with a mean price target of USD 30.53 (range USD 16–37), per Nexqual as of October 29, 2026 at 19:40 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 20 |
| Mean Target | USD 30.53 |
| High Target | USD 37 |
| Low Target | USD 16 |
| Buy / Hold / Sell | 14 / 5 / 1 |
Earnings (ACAD)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD 0.18 |
| Revenue Estimate | $332.55M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD 0.18 vs est 0.04 ▲ beat |
| 2026-03-31 | USD 0.02 vs est 0.08 ▼ miss |
| 2025-12-31 | USD 0.14 vs est 0.14 ▼ miss |
| 2025-09-30 | USD 0.42 vs est 0.15 ▲ beat |
Source: Nexqual, October 29, 2026 at 19:40 UTC.
Financials & Fundamentals (ACAD)
| Total Revenue | $1.14B |
|---|---|
| Revenue Growth (latest quarter, YoY) | +16.40% |
| Gross Margin | +62.06% |
| Operating Margin | +12.29% |
| Profit Margin | +33.42% |
| ROE | +35.74% |
| Debt / Equity | 0.06 |
| Current Ratio | 3.39 |
| Total Cash | $956.47M |
| Total Debt | $73.85M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | $145.63M (12.8% of revenue) |
Source: Nexqual, October 29, 2026 at 19:40 UTC.
Financial Health Score (ACAD)
Nexqual rates Acadia Pharmaceuticals Inc.'s overall financial health "Strong" across five dimensions, as of October 29, 2026 at 19:40 UTC.
| Growth | Solid — Revenue +12% YoY (annual) |
|---|---|
| Profitability | Strong — Gross margin 91%, operating 8% (last 4 quarters to Jun 2026, SEC) |
| Balance Sheet | Strong — $956M cash vs $74M debt, net cash position |
| Cash Flow | Solid — FCF $146M (last 4 quarters to Jun 2026, SEC), 13% margin |
| Efficiency | Strong — ROE 29%, ROA 21.8% (last 4 quarters, SEC) |
Ownership (ACAD)
| Insider Ownership | +0.33% |
|---|---|
| Institutional Ownership | +100.05% |
| Shares Outstanding | 172.31M |
| Float | 128.35M |
| Short % of Float | +8.34% |
Source: Nexqual, October 29, 2026 at 19:40 UTC.
Leadership (ACAD)
Acadia Pharmaceuticals Inc. is led by Catherine E. Owen Adams, CEO & Director, per Nexqual as of October 29, 2026 at 19:40 UTC.
| CEO & Director | Catherine E. Owen Adams |
|---|---|
| Executive VP & CFO | Mark C. Schneyer |
Major Backers & Investors (ACAD)
Notable institutional backers of Acadia Pharmaceuticals Inc. include Baker Bros. Advisors, LP, RTW Investments LP, Palo Alto Investors Lp, according to Nexqual as of October 29, 2026 at 19:40 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Baker Bros. Advisors, LP | 24.91% |
| RTW Investments LP | 4.15% |
| Palo Alto Investors Lp | 1.66% |
| Goldman Sachs | 1.5% |
| Fidelity | 0.82% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 13.07% |
| Vanguard Group | 8.48% |
| State Street | 5.27% |
| Dimensional Fund Advisors | 2.14% |
| Geode Capital | 1.95% |
Source: Nexqual, October 29, 2026 at 19:40 UTC.
From Acadia Pharmaceuticals Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)
Key Strengths & Strategy (as disclosed to the SEC)
- Before commencing clinical investigations in humans, we or our collaborators must submit an Investigational New Drug Application (IND), to the FDA.
- The data and information are submitted to the FDA in the form of a New Drug Application (NDA), which must be accompanied by payment of a significant user fee unless a waiver or exemption applies.
- Our patent applications claim proprietary technology, including chemical synthetic or manufacturing methods, drug assays, novel compounds, compositions, formulations and methods of treatment.
Partnerships
- In July 2023, we expanded the 2018 licensing agreement with Neuren to acquire rights to trofinetide outside of North America as well as global rights to Neuren's development candidate NNZ-2591 in Rett syndrome and Fragile X syndrome.
- In November 2024, we entered into an exclusive worldwide license agreement with Saniona A/S (Saniona) for the development and commercialization of ACP-711 (formerly SAN711).
Legal & Regulatory Risks (Item 1A, quoted)
- We are subject, directly and indirectly, to federal, state and foreign healthcare laws and regulations, including healthcare fraud and abuse laws, false claims laws, physician payment transparency laws and health information privacy and security laws. If we are unable to comply, or have not fully complied, with such laws, we could face substantial penalties.
- We could face liability if a regulatory authority determines that we are promoting our products for any "off-label" uses.
- We are subject to stringent regulation in connection with the marketing of our products, which could delay the development, approval and commercialization of our products.
- We may expend significant resources or fundamentally change our business activities and practices (including our clinical trials) to try to protect against security incidents. Certain data privacy and security obligations may require us to implement and maintain specific security measures or industry-standard or reasonable security measures to protect our information technology systems and sensitive data.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| ORKA | Oruka Therapeutics, Inc. | USD 96.37 | ▲ 0.41% |
| LGND | Ligand Pharmaceuticals Incorpor | USD 319.89 | ▲ 0.35% |
| IOVA | Iovance Biotherapeutics, Inc. | USD 9.69 | ▼ 34.6% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 44.58 | ▼ 0.71% |
| AXSM | Axsome Therapeutics, Inc. | USD 143.52 | ▲ 0.01% |
| ABVX | Abivax SA | USD 89.11 | ▼ 0.82% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 19:40 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt