Arvinas, Inc. (ARVN) Stock Price & Analysis

Arvinas, Inc. (ARVN) closed at USD 7.6 on Wednesday, October 28, 2026, up 2.01% on the day. The US market is currently closed (after-hours); this is not a live price.

The prior close was USD 7.45; the Oct 28, 2026 session ranged USD 7.3–7.67 on volume of 891,286 shares. Market capitalization is $490.36M, with a 52-week range of USD 6.74–14.51 (NMS). Source: Nexqual, retrieved October 28, 2026 at 23:47 UTC.

Also available as compact Markdown for AI agents: nexqual.com/ARVN.md

Key facts (ARVN)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (ARVN)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$53.6M$131M$78.5M$263M$263M$317M
Operating income-$188M-$263M-$402M-$250M-$119M-$18.1M
Net income-$191M-$283M-$367M-$199M-$80.8M$9.3M
EPS (diluted)-$3.82-$5.31-$6.62-$2.77-$1.14—
Free cash flow$555M-$280M-$351M-$261M-$276M-$209M
Operating margin-351.5%-200.3%-511.5%-95.0%-45.1%-5.7%
Net margin-356.3%-215.0%-467.9%-75.5%-30.8%2.9%
Revenue growth+106.9%+145.1%-40.3%+235.5%-0.3%—
Cash + short-term investments$1.50B$1.21B$1.26B$1.04B$685M—
Total debt$1.0M$1.0M$1.0M$800K$600K—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (ARVN)

P/E 52.7x · P/S 1.6x · EV/Sales -0.2x · P/B 0.9x · FCF yield -42.58% · Earnings yield 1.90% · Net cash $567M · EV -$77.0M

Insider sales (SEC Form 4, open-market, last ~7 months) (ARVN)

2 of 8 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-06-24Saik AndrewChief Financial Officer5,696$46K2.9%YesToo little history (no open-market trades in 2023 or 2024)
2026-06-17Cacace Angela MChief Scientific Officer2,576$20K1.4%YesToo little history (no open-market trades in 2023 or 2024)
2026-05-21Teel RandyPresident and CEO2,209$20K0.8%NoToo little history (no open-market trades in 2023–2025)
2026-05-11Saik AndrewChief Financial Officer11,139$111K5.5%NoToo little history (no open-market trades in 2023 or 2024)
2026-05-11Loomis David KVP, Chief Accounting Officer1,919$19K4.6%NoRoutine (sold in Nov each year 2023–2025; this trade is outside those months)
2026-05-11Cacace Angela MChief Scientific Officer9,657$96K5%NoToo little history (no open-market trades in 2023 or 2024)
2026-05-11Berkowitz NoahChief Medical Officer11,108$110K5.5%NoToo little history (no open-market trades in 2023 or 2024)
2026-05-11Teel RandyPresident and CEO9,657$96K3.3%NoToo little history (no open-market trades in 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (ARVN)

Consensus Hold (mean 2.50 on a 1–5 scale), 16 analysts; mean target USD 13.93 (low 6, high 21).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-10Evercore ISI GroupTarget loweredOutperform$19 → $14
2026-08-10CitigroupTarget loweredBuy$24 → $21
2026-08-05Wells FargoDowngradeOverweight → Equal-Weight$15 → $11
2026-08-05WedbushTarget raisedNeutral$11 → $12
2026-08-04BTIGReiteratedBuy$18

Total return (dividends reinvested) (ARVN)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return-20.8%-91.2%
S&P 500 (SPY)+13.6%+79.8%
Per year-20.8%-38.5%
Volatility (annualized)55.2%70.7%
Max drawdown-50.7% (Feb 2026→Oct 2026)-93.1% (Nov 2021→Aug 2025)

ARVN earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 4, 2026Quarter ended Jun 30, 2026$2.58−$0.28Beat +$2.86+4.2%
May 12, 2026Quarter ended Mar 31, 2026−$0.90−$0.96Beat +6.3%+2.2%
Feb 24, 2026Quarter ended Dec 31, 2025−$1.10−$0.57Miss −93.0%+8.1%
Nov 5, 2025Quarter ended Sep 30, 2025−$0.48−$0.74Beat +35.1%+4.8%
Aug 6, 2025————-18.0%
May 1, 2025————-19.8%
Feb 11, 2025————-5.4%
Oct 30, 2024————-3.9%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

ARVN recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 14, 2026Schedule 13G/AD. E. Shaw & Co., L.P., D. E. Shaw & Co., L.L.C.: 5.4% of shares, passive 5%+ holder (amended)
Aug 4, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 4, 20268-KQuarterly results

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

ARVN suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerPfizer (PFE)“•the potential achievement of milestones and receipt of payments under our collaborations, including our collaboration with Pfizer Inc. entered into in July 2021;”
PartnerNovartis Pharma“•the potential receipt of payments based on the achievement of milestones related to luxdegalutamide (ARV-766) and future royalties under our license agreement with Novartis Pharma AG;”
PartnerHoffman-La Roche“In addition to the programs above and our early-stage collaborations, including with Pfizer, Inc., or Pfizer, and Genentech, Inc. and F.”
PartnerBayer“In June 2019, we entered into a Collaboration and License Agreement, or the Bayer Collaboration Agreement, with Bayer, setting forth our collaboration to identify or optimize PROTAC targeted protein degraders that mediate for degradation of Targets, using our proprietary platform technology, that are selected by Bayer, subject to certain exclusions and limitations.”
PartnerAbbVie (ABBV)“Hoffman-La Roche Ltd. and AbbVie and its partner, Genmab.”
CompetitorWuXi“Any unfavorable government policies on international trade, such as export controls, capital controls or tariffs, may increase the cost of manufacturing our product candidates and platform materials, affect the demand for our product candidates (if and once approved), the competitive position of our product candidates, and import or export of raw materials and finished product candidates used in our preclinical st…”

Quoted from the company's 10-K filed Feb 24, 2026.

Companies that name ARVN in their SEC reports

Relationship to ARVNCompanyFilingSentence
partnerMUSTANG BIO, INC. (MBIO)10-K Mar 19, 2026“While at Arvinas, Dr. Litchman oversaw the advancement of the company's pipeline of protein-degradation therapeutics for the treatment of cancers and other diseases toward Investigational New Drug applications and secured multi-target discovery collaborations with Merck and Genentech.”

ARVN analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.95$-0.83−$0.12$16.8M12
Next quarter (ends Dec 2026)$-0.93$-0.85−$0.08$15.5M12
Current fiscal year (ends Dec 2026)$-0.14$-2.86+$2.73$296.1M12
Next fiscal year (ends Dec 2027)$-3.23$-3.45+$0.22$64.2M12

ARVN options: expected move

Options price a move of about ±17.2% (±$1.31) by Nov 20, 2026, which includes earnings on Nov 3, 2026. Over the last 8 reports the stock moved ±8.3% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262384.1%±17.2%
Dec 18, 202651131.9%±40.1%
Jan 15, 20277975.1%±28.6%
Apr 16, 202717083.8%±44.7%

30-day implied volatility 67.5% vs 53.1% realized over the last 30 trading days. Put/call ratio (volume) 0. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 28, 2026 at 23:47 UTC)

PriceUSD 7.6
Change▲ 2.01% (up)
Previous CloseUSD 7.45
OpenUSD 7.39
Day RangeUSD 7.3 – 7.67
52-Week RangeUSD 6.74 – 14.51
Volume891,286 shares
Market Cap$490.36M
ExchangeNMS

Technical Analysis (ARVN)

Nexqual's technical model rates ARVN "SELL" based on 2 bullish and 4 bearish signals across 127 daily candles, as of October 28, 2026 at 23:47 UTC.

Overall SignalSELL
RSI (14)49.5 (neutral)
vs SMA50Below (USD 8.16)
MACD-0.15 (negative)

Analyst Ratings (ARVN)

Wall Street analysts rate ARVN "Hold" based on 16 analysts, with a mean price target of USD 13.93 (range USD 6–21), per Nexqual as of October 28, 2026 at 23:47 UTC.

Consensus RatingHold
Analyst Count16
Mean TargetUSD 13.93
High TargetUSD 21
Low TargetUSD 6
Buy / Hold / Sell7 / 8 / 1

Earnings (ARVN)

Next Earnings Date2026-11-03
EPS EstimateUSD -0.95
Revenue Estimate$16.82M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 2.58 vs est -0.28 ▲ beat
2026-03-31USD -0.9 vs est -0.96 ▲ beat
2025-12-31USD -1.1 vs est -0.57 ▼ miss
2025-09-30USD -0.48 vs est -0.74 ▲ beat

Source: Nexqual, October 28, 2026 at 23:47 UTC.

Financials & Fundamentals (ARVN)

Total Revenue$316.70M
Revenue Growth (latest quarter, YoY)+1014.70%
Gross Margin+97.16%
Operating Margin+66.36%
Profit Margin+2.94%
ROE+1.59%
Debt / Equity0.01
Current Ratio7.91
Total Cash$567.90M
Total Debt$8.00M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$208.80M (-65.9% of revenue)

Source: Nexqual, October 28, 2026 at 23:47 UTC.

Financial Health Score (ARVN)

Nexqual rates Arvinas, Inc.'s overall financial health "Weak" across five dimensions, as of October 28, 2026 at 23:47 UTC.

GrowthWeak — Revenue -0% YoY (annual), declining
ProfitabilityWeak — Operating margin -6%
Balance SheetStrong — $568M cash and investments, no debt (Jun 2026, SEC)
Cash FlowWeak — FCF negative: -$209M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyWeak — ROE 2%, ROA 1.4% (last 4 quarters, SEC)

Ownership (ARVN)

Insider Ownership+7.80%
Institutional Ownership+84.05%
Shares Outstanding64.52M
Float56.81M
Short % of Float+9.97%

Source: Nexqual, October 28, 2026 at 23:47 UTC.

Leadership (ARVN)

Arvinas, Inc. is led by Randy Teel, CEO, President & Director, per Nexqual as of October 28, 2026 at 23:47 UTC.

CEO, President & DirectorRandy Teel
CFO & TreasurerAndrew R. Saik
Chief Scientific OfficerAngela M. Cacace
Vice President of Investor RelationsJeff Boyle

Major Backers & Investors (ARVN)

Notable institutional backers of Arvinas, Inc. include Shaw D.E. & Co., Inc., Pfizer Inc, Armistice Capital, LLC, according to Nexqual as of October 28, 2026 at 23:47 UTC.

Active Investors

InvestorStake
Shaw D.E. & Co., Inc.5.42%
Pfizer Inc5.36%
Armistice Capital, LLC4.33%
Two Sigma Investments, LP3.99%
Qube Research & Technologies Ltd2.47%
Fidelity1.01%

Index Funds (Passive)

FundStake
BlackRock11.79%
Vanguard Group10.6%
State Street3.4%
Geode Capital2.58%

Source: Nexqual, October 28, 2026 at 23:47 UTC.

From Arvinas, Inc.'s Latest SEC 10-K Filing (filed 2026-02-24)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 28, 2026 at 23:47 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt