Avalo Therapeutics, Inc. (AVTX) Stock Price & Analysis

Avalo Therapeutics, Inc. (AVTX) closed at USD 7.12 on Wednesday, October 28, 2026, up 5.48% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 6.75; the Oct 28, 2026 session ranged USD 6.66–7.14 on volume of 2,165,697 shares. Market capitalization is $381.85M, with a 52-week range of USD 6.53–24.27 (NCM). Source: Nexqual, retrieved October 29, 2026 at 07:20 UTC.

Also available as compact Markdown for AI agents: nexqual.com/AVTX.md

Key facts (AVTX)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (AVTX)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$5.4M$18.1M$1.9M$441K$59K—
Gross profit$3.9M$14.6M$640K———
Operating income-$82.1M-$37.4M-$27.4M-$68.5M-$72.9M-$91.4M
Net income-$84.4M-$41.7M-$31.5M-$35.1M-$78.3M-$100M
EPS (diluted)—-$1063.00-$113.58-$20.91-$5.84—
Free cash flow-$71.0M-$26.8M-$30.8M-$49.1M——
Gross margin72.4%81.0%33.3%———
Operating margin-1521.6%-207.4%-1421.6%-15535.6%-123601.7%—
Net margin-1563.1%-230.8%-1639.5%-7965.8%-132642.4%—
Revenue growth-19.4%+234.4%-89.3%-77.1%-86.6%—
Cash + short-term investments$54.6M$13.2M$7.4M$135M$98.3M—
Total debt$32.8M$13.5M$0K———

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (AVTX)

P/B 0.8x · Earnings yield -26.28%

Analysts (AVTX)

Consensus Buy (mean 2.00 on a 1–5 scale), 14 analysts; mean target USD 36.6 (low 10, high 60).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-23GuggenheimDowngradeBuy → Neutral
2026-10-23WedbushTarget loweredOutperform$34 → $22
2026-10-23HC Wainwright & Co.DowngradeBuy → Neutral
2026-10-23BTIGTarget loweredBuy$58 → $10
2026-08-07GuggenheimTarget loweredBuy$50 → $48
2026-08-07HC Wainwright & Co.Target loweredBuy$35 → $30
2026-07-06Leerink PartnersInitiatedOutperform$38

Total return (dividends reinvested) (AVTX)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return-60.5%-99.9%
S&P 500 (SPY)+13.6%+79.8%
Per year-60.7%-74.5%
Volatility (annualized)92.7%169.6%
Max drawdown-70.5% (May 2026→Oct 2026)-100.0% (Nov 2021→May 2025)

AVTX earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 6, 2026Quarter ended Jun 30, 2026−$0.83−$0.62Miss −33.9%-2.8%
May 13, 2026Quarter ended Mar 31, 2026−$0.98−$1.07Beat +8.4%-4.7%
May 7, 2026Quarter ended Mar 31, 2026−$0.98−$1.07Beat +8.4%-1.1%
Mar 23, 2026Quarter ended Dec 31, 2025−$0.37−$1.49Beat +75.2%+0.2%
Jan 12, 2026Quarter ended Dec 31, 2025−$0.37−$1.49Beat +75.2%+1.5%
Nov 6, 2025Quarter ended Sep 30, 2025−$2.19−$1.64Miss −33.5%-8.5%
Aug 7, 2025————+7.5%
May 12, 2025————-9.4%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

AVTX recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 14, 2026Schedule 13G/ANantahala Capital Management, LLC, Wilmot B. Harkey: 3.5% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/ACaligan Partners LP, David Johnson: 5.9% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/ARA Capital Management, L.P., Peter Kolchinsky: 6.3% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/ABIOTECHNOLOGY VALUE FUND L P, BVF I GP LLC: 5.3% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/AT. Rowe Price Investment Management, Inc.: 0.0% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/AAvoro Capital Advisors LLC, Behzad Aghazadeh: 4.4% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/ADeep Track Capital, LP, Deep Track Biotechnology Master Fund, Ltd.: 6.9% of shares, passive 5%+ holder (amended)
Aug 13, 2026Schedule 13G/AAffinity Asset Advisors, LLC, Michael Cho: 5.5% of shares, passive 5%+ holder (amended)
Aug 7, 2026Schedule 13G/Apassive 5%+ holder (amended)
Aug 7, 2026Schedule 13Gpassive 5%+ holder
Aug 6, 2026Schedule 13G/Apassive 5%+ holder (amended)
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 6, 20268-KQuarterly results
Jul 27, 2026Schedule 13Gpassive 5%+ holder

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

AVTX suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
CustomerES Therapeutics“In the event that J&J and/or Apollo are required to make payment(s) to ES Therapeutics pursuant to the underlying agreements, we will recognize revenue under our existing contracts with those customers for that amount when it is no longer probable there would be a significant revenue reversal with any differences between the fair value of the derivative liability related to that payment immediately prior to the re…”
CustomerApollo AP43“In the event that J&J and/or Apollo are required to make payment(s) to ES Therapeutics pursuant to the underlying agreements, we will recognize revenue under our existing contracts with those customers for that amount when it is no longer probable there would be a significant revenue reversal with any differences between the fair value of the derivative liability related to that payment immediately prior to the re…”
PartnerEli Lilly (LLY)“Eli Lilly License Agreement”
PartnerJohnson & Johnson (JNJ)“The economic rights sold include (a) rights to a milestone payment of $20.0 million upon the filing and acceptance of an NDA for AVTX-501 pursuant to an agreement with Janssen Pharmaceutics, Inc., now Johnson & Johnson Innovative Medicine ("J&J") (the "AVTX-501 Milestone") and (b) rights to any future milestone payments and royalties relating to AVTX-007 under a license agreement with Apollo AP43 Limited ("Apollo"…”
PartnerLeap Therapeutics“We have not paid any milestones, royalties or any other amounts under the Lilly License Agreement or the Leap Agreement as of the date of this report.”
PartnerApple (AAPL)“From September 2012 to September 2013, Dr. Neil was a Partner at Apple Tree Partners, a life sciences private equity fund.”
PartnerKyowa Kirin“Under the KKC License Agreement, the Company paid KKC an upfront license fee of $10.0 million, which we recognized within research and development expenses in 2021.”
PartnerAlto Neuroscience, Inc. (ANRO)“Under the out-license agreement, the Company received a mid-six digit upfront payment from Alto, which we recognized as license revenue in 2021.”
CompetitorAbbVie (ABBV)“There are numerous other companies that have commercialized or are developing treatments for HS and inflammatory diseases that we will compete with, including AbbVie, Lilly, Merck, Novartis, Pfizer, Sanofi, Takeda, UCB and others.”
CompetitorMerck (MRK)“There are numerous other companies that have commercialized or are developing treatments for HS and inflammatory diseases that we will compete with, including AbbVie, Lilly, Merck, Novartis, Pfizer, Sanofi, Takeda, UCB and others.”
CompetitorPfizer (PFE)“There are numerous other companies that have commercialized or are developing treatments for HS and inflammatory diseases that we will compete with, including AbbVie, Lilly, Merck, Novartis, Pfizer, Sanofi, Takeda, UCB and others.”

Quoted from the company's 10-K filed Mar 23, 2026.

Companies that name AVTX in their SEC reports

Relationship to AVTXCompanyFilingSentence
partnerAlto Neuroscience, Inc. (ANRO)10-K Mar 16, 2026“In May 2021, we entered into a patent and know-how license agreement, or the Cerecor Agreement, with Cerecor Inc. (n/k/a Avalo Therapeutics, Inc.), or Cerecor, pursuant to which we obtained an exclusive worldwide, royalty-bearing license, with the right to sublicense, under certain patent rights and know-how owned or controlled by Cerecor relating to an NR2B inhibitor compound now known as ALTO-202, including cert…”

AVTX company outlook (results filed Aug 6, 2026)

Quoted word-for-word from the SEC 8-K results press release.

AVTX analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.55$-0.55$0.00$08
Next quarter (ends Dec 2026)$-0.53$-0.66+$0.13$08
Current fiscal year (ends Dec 2026)$-2.72$-2.56−$0.16$08
Next fiscal year (ends Dec 2027)$-2.78$-2.76−$0.01$010

AVTX options: expected move

Options price a move of about ±44.2% (±$3.15) by Nov 20, 2026, which includes earnings on Nov 12, 2026. Over the last 8 reports the stock moved ±4.5% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202623206.9%±44.2%
Dec 18, 20265180.5%±24.9%
Feb 19, 202711499.0%±44.2%
May 21, 202720592.2%±54.4%

30-day implied volatility 76.5% vs 153.1% realized over the last 30 trading days. Put/call ratio (volume) 3.68. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 07:20 UTC)

PriceUSD 7.12
Change▲ 5.48% (up)
Previous CloseUSD 6.75
OpenUSD 6.66
Day RangeUSD 6.66 – 7.14
52-Week RangeUSD 6.53 – 24.27
Volume2,165,697 shares
Market Cap$381.85M
ExchangeNCM

Technical Analysis (AVTX)

Nexqual's technical model rates AVTX "SELL" based on 2 bullish and 5 bearish signals across 127 daily candles, as of October 29, 2026 at 07:20 UTC.

Overall SignalSELL
RSI (14)20.44 (oversold)
vs SMA50Below (USD 15.29)
MACD-2.33 (negative)

Analyst Ratings (AVTX)

Wall Street analysts rate AVTX "Buy" based on 14 analysts, with a mean price target of USD 36.6 (range USD 10–60), per Nexqual as of October 29, 2026 at 07:20 UTC.

Consensus RatingBuy
Analyst Count14
Mean TargetUSD 36.6
High TargetUSD 60
Low TargetUSD 10
Buy / Hold / Sell12 / 2 / 0

Earnings (AVTX)

Next Earnings Date2026-11-12
EPS EstimateUSD -0.55
Revenue Estimate$0

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.83 vs est -0.62 ▼ miss
2026-03-31USD -0.98 vs est -1.07 ▲ beat
2025-12-31USD -0.37 vs est -1.5 ▲ beat
2025-09-30USD -2.19 vs est -1.64 ▼ miss

Source: Nexqual, October 29, 2026 at 07:20 UTC.

Financials & Fundamentals (AVTX)

Total Revenue$59,000
Gross Margin+0.00%
Operating Margin-154847.45%
Profit Margin+0.00%
ROE-36.27%
Debt / Equity0
Current Ratio19.31
Total Cash$400.28M
Total Debt$242,000

Source: Nexqual, October 29, 2026 at 07:20 UTC.

Financial Health Score (AVTX)

Nexqual rates Avalo Therapeutics, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 07:20 UTC.

GrowthCritical — Revenue -87% YoY (annual), sharp decline
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $400M cash, no debt
Cash FlowWeak — Operating cash flow -$51M (FY ended Dec 2025, 10-K)
EfficiencyCritical — ROE -22%, ROA -20.4% (last 4 quarters, SEC)

Ownership (AVTX)

Insider Ownership+1.69%
Institutional Ownership+133.64%
Shares Outstanding53.63M
Float40.11M
Short % of Float+22.34%

Source: Nexqual, October 29, 2026 at 07:20 UTC.

Leadership (AVTX)

Avalo Therapeutics, Inc. is led by Garry A. Neil, President, CEO & Director, per Nexqual as of October 29, 2026 at 07:20 UTC.

President, CEO & DirectorGarry A. Neil
Founder and Chairman of Scientific Advisory BoardSolomon H. Snyder
CFO & Head of Investor relationsChristopher Ryan Sullivan
Senior Vice President of Human ResourcesAshley Ivanowicz
Senior Vice President of CMC & Technical OperationsDino C. Miano

Major Backers & Investors (AVTX)

Notable institutional backers of Avalo Therapeutics, Inc. include FMR, LLC, Deep Track Capital, Lp, Caligan Partners, LP, according to Nexqual as of October 29, 2026 at 07:20 UTC.

Active Investors

InvestorStake
FMR, LLC9.51%
Deep Track Capital, Lp6.73%
Caligan Partners, LP5.9%
TCG Crossover Management, LLC5.63%
Fidelity5.5%
Affinity Asset Advisors, Llc5.41%
Farallon Capital Management LLC4.66%
Point72 Asset Management, L.P.4.45%

Index Funds (Passive)

FundStake
BlackRock8.14%
State Street5.39%

Source: Nexqual, October 29, 2026 at 07:20 UTC.

From Avalo Therapeutics, Inc.'s Latest SEC 10-K Filing (filed 2026-03-23)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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AXSMAxsome Therapeutics, Inc.USD 143.51▲ 0.92%
ABVXAbivax SAUSD 89.84▲ 3.26%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 07:20 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt