Cryoport, Inc. (CYRX) Stock Price & Analysis
Cryoport, Inc. (CYRX) is trading at USD 18.58, down 0.32% today, as of October 29, 2026 at 16:30 UTC (US market open; quotes may be delayed), according to Nexqual market data.
CYRX last closed at USD 18.64; today's session has ranged USD 18.31–18.69 on volume of 125,299 shares. Market capitalization is $941.06M, with a 52-week range of USD 7.61–18.88 (NCM). Source: Nexqual, retrieved October 29, 2026 at 16:34 UTC.
Also available as compact Markdown for AI agents: nexqual.com/CYRX.md
Key facts (CYRX)
- Last four reported quarters (through Jun 30, 2026): revenue $186M, net income -$37.4M (-20.1% margin), free cash flow -$20.0M (SEC filings).
- 1 of 80 tracked superinvestors hold CYRX (13F, Q2 2026): 0 new, 1 added, 0 reduced, 0 unchanged.
- Insider open-market sales, last ~7 months: 4 Form 4 filings, $4.1M; 3 not under a Rule 10b5-1 plan ($3.6M); 0 by opportunistic insiders, 2 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.00 on a 1–5 scale) (9 analysts), mean target USD 19.78 (range 15–26).
- Total return with dividends: 1Y +101.1% vs S&P 500 +13.1%; 5Y -77.2% vs S&P 500 +79.1%.
- Next earnings: 2026-11-05, EPS estimate USD -0.17, revenue estimate $48.7M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (CYRX)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $223M | $237M | $169M | $157M | $176M | $186M |
| Gross profit | $96.6M | $104M | $75.3M | $69.7M | $83.1M | — |
| Operating income | -$17.8M | -$31.9M | -$101M | -$122M | -$36.8M | -$39.6M |
| Net income | -$276M | -$37.3M | -$99.6M | -$115M | $78.3M | -$37.4M |
| EPS (diluted) | -$6.18 | -$0.93 | -$2.21 | -$2.49 | $1.40 | — |
| Free cash flow | -$15.8M | -$24.0M | -$39.5M | -$33.6M | -$25.0M | -$20.0M |
| Gross margin | 43.4% | 43.8% | 44.7% | 44.4% | 47.1% | — |
| Operating margin | -8.0% | -13.4% | -59.6% | -77.6% | -20.9% | -21.2% |
| Net margin | -123.8% | -15.7% | -59.0% | -73.2% | 44.4% | -20.1% |
| Revenue growth | +182.9% | +6.6% | -28.9% | -7.1% | +12.4% | — |
| Cash + short-term investments | $629M | $523M | $457M | $251M | $411M | — |
| Total debt | $404M | $407M | $379M | $184M | $1.1M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (CYRX)
P/S 5.0x · EV/Sales 2.9x · P/B 1.9x · FCF yield -2.13% · Earnings yield -3.97% · Net cash $396M · EV $545M
P/E at fiscal year-ends: Dec 2025 6.1x.
Superinvestors (SEC 13F-HR, Q2 2026) (CYRX)
1 of 80 tracked investors hold CYRX. Each row is the investor's latest 13F; change is vs their prior-quarter share count.
| Investor | Firm | % of portfolio | Value | Change |
|---|---|---|---|---|
| First Eagle Investment | First Eagle Investment Management | 0.03% | $20.0M | Added +70.7% |
Insider sales (SEC Form 4, open-market, last ~7 months) (CYRX)
1 of 4 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-08-11 | Shelton Jerrell | President, CEO | 28,800 | $429K | 2.3% | Yes (adopted May 11, 2026) | Routine (sold in Mar each year 2023–2025; this trade is outside those months) |
| 2026-06-10…2026-06-11 | Zecchini Edward J | Chief Digital and Tech Officer | 35,000 | $508K | 24.2% | No | Too little history (no open-market trades in 2023) |
| 2026-06-08 | Mandalam Ramkumar | Director | 23,214 | $358K | 25.5% | No | Too little history (no open-market trades in 2023) |
| 2026-06-04 | Stefanovich Robert | Chief Financial Officer | 169,427 | $2.8M | 60.7% | No | Routine (sold in Mar each year 2023–2025; this trade is outside those months) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (CYRX)
Consensus Buy (mean 2.00 on a 1–5 scale), 9 analysts; mean target USD 19.78 (low 15, high 26).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-13 | BTIG | Target raised | Buy | $25 → $26 |
| 2026-10-01 | Guggenheim | Target raised | Buy | $16 → $19 |
| 2026-09-18 | BTIG | Reiterated | Buy | $25 |
| 2026-08-07 | Guggenheim | Target raised | Buy | $12 → $16 |
| 2026-08-07 | Needham | Target raised | Buy | $15 → $19 |
| 2026-07-24 | BTIG | Target raised | Buy | $17 → $25 |
Total return (dividends reinvested) (CYRX)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +101.1% | -77.2% |
| S&P 500 (SPY) | +13.1% | +79.1% |
| Per year | +101.2% | -25.6% |
| Volatility (annualized) | 45.8% | 68.2% |
| Max drawdown | -31.5% (Jan 2026→Mar 2026) | -93.4% (Oct 2021→Mar 2025) |
CYRX earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| — | Quarter ended Jun 30, 2026 | −$0.20 | −$0.18 | Miss −11.1% | — |
| — | Quarter ended Mar 31, 2026 | −$0.19 | −$0.19 | In line | — |
| — | Quarter ended Dec 31, 2025 | −$0.17 | −$0.21 | Beat +19.0% | — |
| — | Quarter ended Sep 30, 2025 | −$0.13 | −$0.19 | Beat +31.6% | — |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
CYRX recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Aug 14, 2026 | Schedule 13G/A | Cadian Capital Management, LP, Cadian Capital Management GP, LLC: 5.8% of shares, passive 5%+ holder (amended) |
| Aug 13, 2026 | Schedule 13G/A | Morgan Stanley, Morgan Stanley Capital Services LLC: 4.5% of shares, passive 5%+ holder (amended) |
| Aug 6, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 6, 2026 | 8-K | Quarterly results |
| Jul 29, 2026 | Schedule 13G/A | Integrated Core Strategies (US) LLC, Millennium Management LLC: 3.4% of shares, passive 5%+ holder (amended) |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
CYRX suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | DHL Supply Chain International Holding | “The divestiture and strategic partnership with DHL are expected to enhance our ability to develop our business, particularly in the Europe, the Middle East, and Africa (EMEA) and Asia-Pacific (APAC) regions, and to provide differentiated and high-value services aligned with our long-term growth strategy.” |
| Competitor | Cencora (COR) | “Life Sciences Services competition is primarily with specialty couriers, who fall into the category of coopetition and include companies such as World Courier (a Cencora company), UPS Healthcare, Quick (a Kuehne+Nagel company), and Biocair.” |
| Competitor | UPS (UPS) | “Life Sciences Services competition is primarily with specialty couriers, who fall into the category of coopetition and include companies such as World Courier (a Cencora company), UPS Healthcare, Quick (a Kuehne+Nagel company), and Biocair.” |
Quoted from the company's 10-K filed Mar 5, 2026.
CYRX analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-0.17 | $-0.16 | −$0.01 | $48.7M | 3 |
| Next quarter (ends Dec 2026) | $-0.17 | $-0.15 | −$0.02 | $50.0M | 3 |
| Current fiscal year (ends Dec 2026) | $-0.77 | $-0.73 | −$0.04 | $195.5M | 3 |
| Next fiscal year (ends Dec 2027) | $-0.66 | $-0.62 | −$0.04 | $215.2M | 3 |
Key Statistics (as of October 29, 2026 at 16:34 UTC)
| Price | USD 18.58 |
|---|---|
| Change | ▼ 0.32% (down) |
| Previous Close | USD 18.64 |
| Open | USD 18.66 |
| Day Range | USD 18.31 – 18.69 |
| 52-Week Range | USD 7.61 – 18.88 |
| Volume | 125,299 shares |
| Market Cap | $941.06M |
| Exchange | NCM |
Technical Analysis (CYRX)
Nexqual's technical model rates CYRX "BUY" based on 5 bullish and 1 bearish signals across 128 daily candles, as of October 29, 2026 at 16:34 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 64.66 (neutral) |
| vs SMA50 | Above (USD 16.95) |
| MACD | 0.42 (positive) |
Analyst Ratings (CYRX)
Wall Street analysts rate CYRX "Buy" based on 9 analysts, with a mean price target of USD 19.78 (range USD 15–26), per Nexqual as of October 29, 2026 at 16:34 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 9 |
| Mean Target | USD 19.78 |
| High Target | USD 26 |
| Low Target | USD 15 |
| Buy / Hold / Sell | 8 / 1 / 0 |
Earnings (CYRX)
| Next Earnings Date | 2026-11-05 |
|---|---|
| EPS Estimate | USD -0.17 |
| Revenue Estimate | $48.69M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -0.2 vs est -0.18 ▼ miss |
| 2026-03-31 | USD -0.19 vs est -0.19 ▲ beat |
| 2025-12-31 | USD -0.17 vs est -0.21 ▲ beat |
| 2025-09-30 | USD -0.13 vs est -0.19 ▲ beat |
Source: Nexqual, October 29, 2026 at 16:34 UTC.
Financials & Fundamentals (CYRX)
| Total Revenue | $186.45M |
|---|---|
| Revenue Growth (latest quarter, YoY) | +7.70% |
| Gross Margin | +47.08% |
| Operating Margin | -20.45% |
| Profit Margin | -20.05% |
| ROE | -6.54% |
| Debt / Equity | 0.47 |
| Current Ratio | 2.08 |
| Total Cash | $396.69M |
| Total Debt | $232.02M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$20.03M (-10.7% of revenue) |
Source: Nexqual, October 29, 2026 at 16:34 UTC.
Financial Health Score (CYRX)
Nexqual rates Cryoport, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 16:34 UTC.
| Growth | Critical — Revenue -23% YoY (annual), sharp decline |
|---|---|
| Profitability | Mixed — Gross margin 47%, operating -21% (last 4 quarters to Jun 2026, SEC) |
| Balance Sheet | Strong — $397M cash and investments, no debt (Jun 2026, SEC) |
| Cash Flow | Weak — FCF negative: -$20M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE -8%, ROA -4.9% (last 4 quarters, SEC) |
Ownership (CYRX)
| Insider Ownership | +3.86% |
|---|---|
| Institutional Ownership | +94.91% |
| Shares Outstanding | 50.65M |
| Float | 45.95M |
| Short % of Float | +6.02% |
Source: Nexqual, October 29, 2026 at 16:34 UTC.
Leadership (CYRX)
Cryoport, Inc. is led by Jerrell W. Shelton, Chairman, President & CEO, per Nexqual as of October 29, 2026 at 16:34 UTC.
| Chairman, President & CEO | Jerrell W. Shelton |
|---|---|
| Senior VP, CFO, Treasurer & Chief Administrative Officer | Robert S. Stefanovich MS |
| Senior VP & Chief Scientific Officer | Mark W. Sawicki |
| Vice President of Corporate Development & Investor Relations | Thomas J. Heinzen |
| Vice President of Global Human Resources & Organizational Development | Kylie A. Crowe |
Major Backers & Investors (CYRX)
Notable institutional backers of Cryoport, Inc. include Cadian Capital Management, LP, Morgan Stanley, Millennium Management, according to Nexqual as of October 29, 2026 at 16:34 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Cadian Capital Management, LP | 5.77% |
| Morgan Stanley | 4.5% |
| Millennium Management | 3.41% |
| Fred Alger Management, LLC | 3.05% |
| MAK Capital One LLC | 2.52% |
| First Eagle Investment Management, LLC | 2.51% |
| ALGER FUNDS-Alger Small Cap Focus Fund | 2.11% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 8.33% |
| Vanguard Group | 4.25% |
| Geode Capital | 2.59% |
Source: Nexqual, October 29, 2026 at 16:34 UTC.
From Cryoport, Inc.'s Latest SEC 10-K Filing (filed 2026-03-05)
Key Strengths & Strategy (as disclosed to the SEC)
- Our integrated temperature-controlled supply chain solutions combine advanced logistics, biostorage, kitting and labelling, clinical sample management, collection and cryopreservation services for cell therapies starting materials, cryogenic systems manufacturing, and an industry-leading informatics platform that integrates all our solutions.
- We operate a Global Supply Chain Center Network through which we provide our BioLogistics, BioStorage, BioServices, and Cryopreservation services, supporting the end-to-end requirements of the life sciences industry.
- Cryoport continues to expand the foundations for its fully integrated solutions through ongoing enhancements to the Cryoportal, broader deployment of its Smartpak® Condition Monitoring System and Tec4med IoT-based monitoring solutions, and deeper integration of quality systems such as Chain of Compliance.
- Patents provide some degree of protection for our proprietary technology.
Partnerships
- The divestiture and strategic partnership with DHL are expected to enhance our ability to develop our business, particularly in the Europe, the Middle East, and Africa (EMEA) and Asia-Pacific (APAC) regions, and to provide differentiated and high-value services aligned with our long-term growth strategy.
- We also entered into certain related agreements in connection with the transaction, including a master partnership agreement.
Legal & Regulatory Risks (Item 1A, quoted)
- Changes in trade policy, tariff and import/export regulations may have a material adverse effect on our business, financial condition and results of operations.
- We, along with our customers, are subject to various international governmental regulations. Compliance with or changes in such regulations may cause us to incur significant expenses, and if we fail to maintain satisfactory compliance with certain regulations, we may be forced to recall products and cease their manufacture and distribution, and we could be subject to civil or criminal penalties.
- We are subject to regulation by the FDA or certain similar foreign regulatory agencies, and failure to comply with such regulations could harm our reputation, business, financial condition and results of operations.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| FWRD | Forward Air Corporation | USD 17.51 | ▼ 0.2% |
| HUBG | Hub Group, Inc. | USD 26.52 | ▲ 0.95% |
| RLGT | Radiant Logistics, Inc. | USD 9.1 | ▲ 0.65% |
| PBI | Pitney Bowes Inc. | USD 16.93 | ▼ 2.92% |
| LSTR | Landstar System, Inc. | USD 139.79 | ▲ 0.71% |
| GXO | GXO Logistics, Inc. | USD 49.77 | ▲ 0.79% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 16:34 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt