Cryoport, Inc. (CYRX) Stock Price & Analysis

Cryoport, Inc. (CYRX) is trading at USD 18.58, down 0.32% today, as of October 29, 2026 at 16:30 UTC (US market open; quotes may be delayed), according to Nexqual market data.

CYRX last closed at USD 18.64; today's session has ranged USD 18.31–18.69 on volume of 125,299 shares. Market capitalization is $941.06M, with a 52-week range of USD 7.61–18.88 (NCM). Source: Nexqual, retrieved October 29, 2026 at 16:34 UTC.

Also available as compact Markdown for AI agents: nexqual.com/CYRX.md

Key facts (CYRX)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (CYRX)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$223M$237M$169M$157M$176M$186M
Gross profit$96.6M$104M$75.3M$69.7M$83.1M—
Operating income-$17.8M-$31.9M-$101M-$122M-$36.8M-$39.6M
Net income-$276M-$37.3M-$99.6M-$115M$78.3M-$37.4M
EPS (diluted)-$6.18-$0.93-$2.21-$2.49$1.40—
Free cash flow-$15.8M-$24.0M-$39.5M-$33.6M-$25.0M-$20.0M
Gross margin43.4%43.8%44.7%44.4%47.1%—
Operating margin-8.0%-13.4%-59.6%-77.6%-20.9%-21.2%
Net margin-123.8%-15.7%-59.0%-73.2%44.4%-20.1%
Revenue growth+182.9%+6.6%-28.9%-7.1%+12.4%—
Cash + short-term investments$629M$523M$457M$251M$411M—
Total debt$404M$407M$379M$184M$1.1M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (CYRX)

P/S 5.0x · EV/Sales 2.9x · P/B 1.9x · FCF yield -2.13% · Earnings yield -3.97% · Net cash $396M · EV $545M

P/E at fiscal year-ends: Dec 2025 6.1x.

Superinvestors (SEC 13F-HR, Q2 2026) (CYRX)

1 of 80 tracked investors hold CYRX. Each row is the investor's latest 13F; change is vs their prior-quarter share count.

InvestorFirm% of portfolioValueChange
First Eagle InvestmentFirst Eagle Investment Management0.03%$20.0MAdded +70.7%

Insider sales (SEC Form 4, open-market, last ~7 months) (CYRX)

1 of 4 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-08-11Shelton JerrellPresident, CEO28,800$429K2.3%Yes (adopted May 11, 2026)Routine (sold in Mar each year 2023–2025; this trade is outside those months)
2026-06-10…2026-06-11Zecchini Edward JChief Digital and Tech Officer35,000$508K24.2%NoToo little history (no open-market trades in 2023)
2026-06-08Mandalam RamkumarDirector23,214$358K25.5%NoToo little history (no open-market trades in 2023)
2026-06-04Stefanovich RobertChief Financial Officer169,427$2.8M60.7%NoRoutine (sold in Mar each year 2023–2025; this trade is outside those months)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (CYRX)

Consensus Buy (mean 2.00 on a 1–5 scale), 9 analysts; mean target USD 19.78 (low 15, high 26).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-13BTIGTarget raisedBuy$25 → $26
2026-10-01GuggenheimTarget raisedBuy$16 → $19
2026-09-18BTIGReiteratedBuy$25
2026-08-07GuggenheimTarget raisedBuy$12 → $16
2026-08-07NeedhamTarget raisedBuy$15 → $19
2026-07-24BTIGTarget raisedBuy$17 → $25

Total return (dividends reinvested) (CYRX)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+101.1%-77.2%
S&P 500 (SPY)+13.1%+79.1%
Per year+101.2%-25.6%
Volatility (annualized)45.8%68.2%
Max drawdown-31.5% (Jan 2026→Mar 2026)-93.4% (Oct 2021→Mar 2025)

CYRX earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
—Quarter ended Jun 30, 2026−$0.20−$0.18Miss −11.1%—
—Quarter ended Mar 31, 2026−$0.19−$0.19In line—
—Quarter ended Dec 31, 2025−$0.17−$0.21Beat +19.0%—
—Quarter ended Sep 30, 2025−$0.13−$0.19Beat +31.6%—

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

CYRX recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 14, 2026Schedule 13G/ACadian Capital Management, LP, Cadian Capital Management GP, LLC: 5.8% of shares, passive 5%+ holder (amended)
Aug 13, 2026Schedule 13G/AMorgan Stanley, Morgan Stanley Capital Services LLC: 4.5% of shares, passive 5%+ holder (amended)
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 6, 20268-KQuarterly results
Jul 29, 2026Schedule 13G/AIntegrated Core Strategies (US) LLC, Millennium Management LLC: 3.4% of shares, passive 5%+ holder (amended)

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

CYRX suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerDHL Supply Chain International Holding“The divestiture and strategic partnership with DHL are expected to enhance our ability to develop our business, particularly in the Europe, the Middle East, and Africa (EMEA) and Asia-Pacific (APAC) regions, and to provide differentiated and high-value services aligned with our long-term growth strategy.”
CompetitorCencora (COR)“Life Sciences Services competition is primarily with specialty couriers, who fall into the category of coopetition and include companies such as World Courier (a Cencora company), UPS Healthcare, Quick (a Kuehne+Nagel company), and Biocair.”
CompetitorUPS (UPS)“Life Sciences Services competition is primarily with specialty couriers, who fall into the category of coopetition and include companies such as World Courier (a Cencora company), UPS Healthcare, Quick (a Kuehne+Nagel company), and Biocair.”

Quoted from the company's 10-K filed Mar 5, 2026.

CYRX analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.17$-0.16−$0.01$48.7M3
Next quarter (ends Dec 2026)$-0.17$-0.15−$0.02$50.0M3
Current fiscal year (ends Dec 2026)$-0.77$-0.73−$0.04$195.5M3
Next fiscal year (ends Dec 2027)$-0.66$-0.62−$0.04$215.2M3

Key Statistics (as of October 29, 2026 at 16:34 UTC)

PriceUSD 18.58
Change▼ 0.32% (down)
Previous CloseUSD 18.64
OpenUSD 18.66
Day RangeUSD 18.31 – 18.69
52-Week RangeUSD 7.61 – 18.88
Volume125,299 shares
Market Cap$941.06M
ExchangeNCM

Technical Analysis (CYRX)

Nexqual's technical model rates CYRX "BUY" based on 5 bullish and 1 bearish signals across 128 daily candles, as of October 29, 2026 at 16:34 UTC.

Overall SignalBUY
RSI (14)64.66 (neutral)
vs SMA50Above (USD 16.95)
MACD0.42 (positive)

Analyst Ratings (CYRX)

Wall Street analysts rate CYRX "Buy" based on 9 analysts, with a mean price target of USD 19.78 (range USD 15–26), per Nexqual as of October 29, 2026 at 16:34 UTC.

Consensus RatingBuy
Analyst Count9
Mean TargetUSD 19.78
High TargetUSD 26
Low TargetUSD 15
Buy / Hold / Sell8 / 1 / 0

Earnings (CYRX)

Next Earnings Date2026-11-05
EPS EstimateUSD -0.17
Revenue Estimate$48.69M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.2 vs est -0.18 ▼ miss
2026-03-31USD -0.19 vs est -0.19 ▲ beat
2025-12-31USD -0.17 vs est -0.21 ▲ beat
2025-09-30USD -0.13 vs est -0.19 ▲ beat

Source: Nexqual, October 29, 2026 at 16:34 UTC.

Financials & Fundamentals (CYRX)

Total Revenue$186.45M
Revenue Growth (latest quarter, YoY)+7.70%
Gross Margin+47.08%
Operating Margin-20.45%
Profit Margin-20.05%
ROE-6.54%
Debt / Equity0.47
Current Ratio2.08
Total Cash$396.69M
Total Debt$232.02M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$20.03M (-10.7% of revenue)

Source: Nexqual, October 29, 2026 at 16:34 UTC.

Financial Health Score (CYRX)

Nexqual rates Cryoport, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 16:34 UTC.

GrowthCritical — Revenue -23% YoY (annual), sharp decline
ProfitabilityMixed — Gross margin 47%, operating -21% (last 4 quarters to Jun 2026, SEC)
Balance SheetStrong — $397M cash and investments, no debt (Jun 2026, SEC)
Cash FlowWeak — FCF negative: -$20M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -8%, ROA -4.9% (last 4 quarters, SEC)

Ownership (CYRX)

Insider Ownership+3.86%
Institutional Ownership+94.91%
Shares Outstanding50.65M
Float45.95M
Short % of Float+6.02%

Source: Nexqual, October 29, 2026 at 16:34 UTC.

Leadership (CYRX)

Cryoport, Inc. is led by Jerrell W. Shelton, Chairman, President & CEO, per Nexqual as of October 29, 2026 at 16:34 UTC.

Chairman, President & CEOJerrell W. Shelton
Senior VP, CFO, Treasurer & Chief Administrative OfficerRobert S. Stefanovich MS
Senior VP & Chief Scientific OfficerMark W. Sawicki
Vice President of Corporate Development & Investor RelationsThomas J. Heinzen
Vice President of Global Human Resources & Organizational DevelopmentKylie A. Crowe

Major Backers & Investors (CYRX)

Notable institutional backers of Cryoport, Inc. include Cadian Capital Management, LP, Morgan Stanley, Millennium Management, according to Nexqual as of October 29, 2026 at 16:34 UTC.

Active Investors

InvestorStake
Cadian Capital Management, LP5.77%
Morgan Stanley4.5%
Millennium Management3.41%
Fred Alger Management, LLC3.05%
MAK Capital One LLC2.52%
First Eagle Investment Management, LLC2.51%
ALGER FUNDS-Alger Small Cap Focus Fund2.11%

Index Funds (Passive)

FundStake
BlackRock8.33%
Vanguard Group4.25%
Geode Capital2.59%

Source: Nexqual, October 29, 2026 at 16:34 UTC.

From Cryoport, Inc.'s Latest SEC 10-K Filing (filed 2026-03-05)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 16:34 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt