Guardant Health, Inc. (GH) Stock Price & Analysis

Guardant Health, Inc. (GH) closed at USD 162.94 on Thursday, October 22, 2026, down 2.23% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 166.66; the Oct 22, 2026 session ranged USD 158.68–167.25 on volume of 1,770,605 shares. Market capitalization is $21.87B, with a 52-week range of USD 66.59–191.05 (NMS). Source: Nexqual, retrieved October 23, 2026 at 09:14 UTC.

Also available as compact Markdown for AI agents: nexqual.com/GH.md

Key facts (GH)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (GH)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$374M$450M$564M$739M$982M$1.18B
Gross profit——$337M$449M$633M—
Operating income-$411M-$544M-$565M-$444M-$437M-$470M
Net income-$385M-$655M-$479M-$436M-$416M-$453M
EPS (diluted)-$4.00-$6.41-$4.28-$3.56-$3.32—
Free cash flow-$284M-$387M-$345M-$275M-$233M-$241M
Gross margin——59.7%60.8%64.5%—
Operating margin-110.0%-121.1%-100.1%-60.0%-44.5%-39.7%
Net margin-103.0%-145.6%-85.0%-59.0%-42.4%-38.3%
Revenue growth+30.3%+20.3%+25.5%+31.0%+32.9%—
Cash + short-term investments$933M$1.01B$1.17B$840M$1.20B—
Total debt$1.13B$1.14B$1.14B$1.14B$1.50B—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (GH)

P/S 18.5x · EV/Sales 18.9x · FCF yield -1.10% · Earnings yield -2.07% · Buyback yield (TTM) 0.00% · Net debt $449M · EV $22.3B

Superinvestors (SEC 13F-HR, Q2 2026) (GH)

1 of 80 tracked investors hold GH. Each row is the investor's latest 13F; change is vs their prior-quarter share count.

InvestorFirm% of portfolioValueChange
Polen CapitalPolen Capital Management0.04%$5.2MReduced -1.0%

Analysts (GH)

Consensus Buy (mean 1.96 on a 1–5 scale), 26 analysts; mean target USD 201.64 (low 105, high 240).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-13Morgan StanleyTarget raisedOverweight$185 → $200
2026-10-07BarclaysTarget raisedOverweight$200 → $220
2026-10-01GuggenheimTarget raisedBuy$190 → $200
2026-09-09UBSTarget raisedBuy$175 → $225
2026-09-08Rothschild & CoInitiatedBuy$203
2026-09-02BTIGReiteratedBuy$195
2026-08-04Piper SandlerTarget raisedOverweight$135 → $193
2026-08-04Stephens & Co.Target raisedOverweight$170 → $195
2026-08-04Morgan StanleyTarget raisedOverweight$175 → $185
2026-08-03StifelTarget raisedBuy$130 → $180
2026-07-31RBC CapitalTarget raisedOutperform$185 → $200
2026-07-31MizuhoTarget raisedOutperform$175 → $200

Total return (dividends reinvested) (GH)

1Y (from 2025-10-23)5Y (from 2021-10-18)
Total return+134.9%+49.0%
S&P 500 (SPY)+14.9%+80.3%
Per year+135.6%+8.3%
Volatility (annualized)56.9%69.3%
Max drawdown-33.0% (Jan 2026→Apr 2026)-86.2% (Oct 2021→Apr 2024)

GH revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Oncology$219.1M65.4%+38.1%
Biopharma Data$60.9M18.2%+8.8%
Screening$52.9M15.8%+256.9%
Licensing Other$2.1M0.6%-19.8%
Total revenue$335.0M100%—

GH revenue by region (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
United States$318.0M94.9%+46.8%
International$16.9M5.1%+10.0%
Total revenue$335.0M100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

GH suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
SupplierILLUMINA, INC. (ILMN)“In September 2014, we entered into a supply agreement with Illumina, Inc., or Illumina, for Illumina to provide products and services that can be used for certain research and clinical activities, including certain sequencers, reagents, and other consumables for use with the Illumina sequencers, as well as service contracts for the maintenance and repair of the sequencers.”
PartnerAdicon Holdings“In June 2022, we signed a strategic partnership agreement with Adicon Holdings Limited, or Adicon, a leading independent clinical laboratory company based in China, and in December 2023, the blood-based cancer testing services based on our digital sequencing platform became available at Adicon's testing facility, which offers our industry-leading comprehensive genomic profiling tests to biopharmaceutical companies…”

Quoted from the company's 10-K filed Feb 19, 2026.

GH customer concentration

In the period ended Jun 30, 2026, a single direct customer accounted for 27% of revenue, per the company's 10-Q filed Jul 30, 2026. The company does not name it.

GH company outlook (results filed Jul 30, 2026)

Analysts expect $350.6M for the current quarter, 74.0% below the midpoint of the company's guidance ($1.35B).

Quoted word-for-word from the SEC 8-K results press release.

GH analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.31$-0.30+4.5%$350.6M17
Next quarter (ends Dec 2026)$-0.28$-0.27+2.1%$369.1M17
Current fiscal year (ends Dec 2026)$-1.45$-1.39+3.8%$1.36B21
Next fiscal year (ends Dec 2027)$-0.38$-0.43-12.5%$1.84B19

GH options: expected move

Options price a move of about ±16.3% (±$26.60) by Nov 20, 2026, which includes earnings on Nov 5, 2026. Over the last 8 reports the stock moved ±9.4% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262872.2%±16.3%
Dec 18, 20265662.2%±19.7%
Jan 15, 20278458.5%±22.5%
Mar 19, 202714758.6%±29.6%
Apr 16, 202717558.1%±32.0%
May 21, 202721058.9%±35.5%
Jun 17, 202723757.8%±37.0%

30-day implied volatility 70.2% vs 49.3% realized over the last 30 trading days. Put/call ratio (volume) 1.64. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 23, 2026 at 09:14 UTC)

PriceUSD 162.94
Change▼ 2.23% (down)
Previous CloseUSD 166.66
OpenUSD 165.03
Day RangeUSD 158.68 – 167.25
52-Week RangeUSD 66.59 – 191.05
Volume1,770,605 shares
Market Cap$21.87B
ExchangeNMS

Technical Analysis (GH)

Nexqual's technical model rates GH "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 23, 2026 at 09:14 UTC.

Overall SignalSTRONG SELL
RSI (14)47.29 (neutral)
vs SMA50Below (USD 167.76)
MACD-2.18 (negative)

Analyst Ratings (GH)

Wall Street analysts rate GH "Buy" based on 26 analysts, with a mean price target of USD 201.64 (range USD 105–240), per Nexqual as of October 23, 2026 at 09:14 UTC.

Consensus RatingBuy
Analyst Count26
Mean TargetUSD 201.64
High TargetUSD 240
Low TargetUSD 105
Buy / Hold / Sell25 / 0 / 1

Earnings (GH)

Next Earnings Date2026-11-05
EPS EstimateUSD -0.31
Revenue Estimate$350.64M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.42 vs est -0.39 ▼ miss
2026-03-31USD -0.45 vs est -0.47 ▲ beat
2025-12-31USD -0.5 vs est -0.47 ▼ miss
2025-09-30USD -0.39 vs est -0.49 ▲ beat

Source: Nexqual, October 23, 2026 at 09:14 UTC.

Financials & Fundamentals (GH)

Total Revenue$1.18B
Revenue Growth (latest quarter, YoY)+44.30%
Gross Margin+65.01%
Operating Margin-38.25%
Profit Margin-38.33%
Current Ratio4.03
Total Cash$1.05B
Total Debt$1.70B
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$240.72M (-20.3% of revenue)

Source: Nexqual, October 23, 2026 at 09:14 UTC.

Financial Health Score (GH)

Nexqual rates Guardant Health, Inc.'s overall financial health "Mixed" across five dimensions, as of October 23, 2026 at 09:14 UTC.

GrowthStrong — Revenue +33% YoY (annual)
ProfitabilitySolid — Gross margin 65%, operating -38% (last 12 months)
Balance SheetMixed — $1.05B cash and investments vs $1.50B debt (Jun 2026, SEC)
Cash FlowWeak — FCF negative: -$241M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyMixed — No data

Ownership (GH)

Insider Ownership+3.98%
Institutional Ownership+101.04%
Shares Outstanding134.20M
Float129.48M
Short % of Float+9.25%

Source: Nexqual, October 23, 2026 at 09:14 UTC.

Leadership (GH)

Guardant Health, Inc. is led by Helmy Eltoukhy, Co-Founder, Co-CEO & Chairman, per Nexqual as of October 23, 2026 at 09:14 UTC.

Co-Founder, Co-CEO & ChairmanHelmy Eltoukhy
Co-CEO & DirectorAmirAli Talasaz
Chief Financial OfficerMichael Bell
Chief Technology OfficerDarya Chudova
Senior Vice President of OperationsAndy Ament

Major Backers & Investors (GH)

Notable institutional backers of Guardant Health, Inc. include Price (T.Rowe) Associates Inc, FMR, LLC, Invesco, according to Nexqual as of October 23, 2026 at 09:14 UTC.

Active Investors

InvestorStake
Price (T.Rowe) Associates Inc4.85%
FMR, LLC4.09%
Invesco3.3%
Goldman Sachs2.81%
Two Sigma Investments, LP2.77%
Capital International Investors2.53%
Deep Track Capital, Lp2.53%
T. Rowe Price1.33%

Index Funds (Passive)

FundStake
Vanguard Group8.35%
BlackRock5.68%

Source: Nexqual, October 23, 2026 at 09:14 UTC.

From Guardant Health, Inc.'s Latest SEC 10-K Filing (filed 2026-02-19)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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LHLabcorp Holdings Inc.USD 329.93▲ 1.91%
RVTYRevvity, Inc.USD 157.36▲ 0.48%
CRLCharles River Laboratories InteUSD 339.66▼ 1.51%
ICLRICON plcUSD 185.43▲ 0.1%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 09:14 UTC. This page is informational and not investment advice.

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