GH Research PLC (GHRS) Stock Price & Analysis

GH Research PLC (GHRS) closed at USD 20.71 on Wednesday, October 28, 2026, up 3.45% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 20.02; the Oct 28, 2026 session ranged USD 19.52–20.79 on volume of 198,718 shares. Market capitalization is $1.42B, with a 52-week range of USD 12.04–31.44 (NGM). Source: Nexqual, retrieved October 29, 2026 at 12:56 UTC.

Also available as compact Markdown for AI agents: nexqual.com/GHRS.md

Key facts (GHRS)

Analysts (GHRS)

Consensus Buy (mean 1.70 on a 1–5 scale), 10 analysts; mean target USD 42.89 (low 38, high 65).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-07GuggenheimTarget raisedBuy$34 → $40
2026-08-07Cantor FitzgeraldTarget raisedOverweight$35 → $40
2026-08-06NeedhamTarget raisedBuy$32 → $39
2026-07-27Wells FargoInitiatedOverweight$44

Total return (dividends reinvested) (GHRS)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+50.4%-18.2%
S&P 500 (SPY)+13.6%+79.8%
Per year+50.6%-3.9%
Volatility (annualized)69.9%69.2%
Max drawdown-41.0% (Aug 2026→Oct 2026)-79.2% (Nov 2021→Jan 2024)

GHRS earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
—Quarter ended Jun 30, 2026−$0.23−$0.30Beat +23.3%—
—Quarter ended Mar 31, 2026−$0.31−$0.26Miss −19.2%—
—Quarter ended Dec 31, 2025−$0.22−$0.27Beat +18.5%—
—Quarter ended Sep 30, 2025−$0.23−$0.23In line—

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

GHRS recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 9, 20266-KCurrent report (foreign issuer) · period ended Oct 9, 2026
Sep 11, 20266-KCurrent report (foreign issuer) · period ended Sep 11, 2026
Aug 14, 2026Schedule 13G/ARA Capital Management, L.P., Peter Kolchinsky: 7.1% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/ALynx1 Capital Management LP, Weston Nichols: 19.3% of shares, passive 5%+ holder (amended)
Aug 6, 20266-KCurrent report (foreign issuer) · period ended Jun 30, 2026

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

GHRS analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.30$-0.36+$0.06$09
Next quarter (ends Dec 2026)$-0.35$-0.42+$0.07$09
Current fiscal year (ends Dec 2026)$-1.17$-1.40+$0.23$09
Next fiscal year (ends Dec 2027)$-1.85$-2.00+$0.15$09

GHRS options: expected move

Options price a move of about ±24.4% (±$5.05) by Nov 20, 2026, which includes earnings on Nov 5, 2026.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202622123.8%±24.4%
Dec 18, 20265090.5%±26.4%
Jan 15, 20277877.8%±26.3%
Apr 16, 202716965.6%±34.5%

30-day implied volatility 78.2% vs 56.5% realized over the last 30 trading days. Put/call ratio (volume) 0. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 12:56 UTC)

PriceUSD 20.71
Change▲ 3.45% (up)
Previous CloseUSD 20.02
OpenUSD 19.91
Day RangeUSD 19.52 – 20.79
52-Week RangeUSD 12.04 – 31.44
Volume198,718 shares
Market Cap$1.42B
ExchangeNGM

Technical Analysis (GHRS)

Nexqual's technical model rates GHRS "SELL" based on 2 bullish and 4 bearish signals across 127 daily candles, as of October 29, 2026 at 12:56 UTC.

Overall SignalSELL
RSI (14)46.35 (neutral)
vs SMA50Below (USD 24.38)
MACD-1.46 (negative)

Analyst Ratings (GHRS)

Wall Street analysts rate GHRS "Buy" based on 10 analysts, with a mean price target of USD 42.89 (range USD 38–65), per Nexqual as of October 29, 2026 at 12:56 UTC.

Consensus RatingBuy
Analyst Count10
Mean TargetUSD 42.89
High TargetUSD 65
Low TargetUSD 38
Buy / Hold / Sell10 / 0 / 0

Earnings (GHRS)

Next Earnings Date2026-11-05
EPS EstimateUSD -0.3
Revenue Estimate$0

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.23 vs est -0.3 ▲ beat
2026-03-31USD -0.31 vs est -0.26 ▼ miss
2025-12-31USD -0.22 vs est -0.27 ▲ beat
2025-09-30USD -0.23 vs est -0.23 ▼ miss

Source: Nexqual, October 29, 2026 at 12:56 UTC.

Financials & Fundamentals (GHRS)

Gross Margin+0.00%
Operating Margin+0.00%
Profit Margin+0.00%
ROE-18.79%
Debt / Equity0
Current Ratio28.7
Total Cash$362.65M
Total Debt$360,000

Source: Nexqual, October 29, 2026 at 12:56 UTC.

Financial Health Score (GHRS)

Nexqual rates GH Research PLC's overall financial health "Mixed" across five dimensions, as of October 29, 2026 at 12:56 UTC.

GrowthMixed — No data
ProfitabilityWeak — Pre-revenue or very early stage
Balance SheetStrong — $363M cash, no debt
Cash FlowWeak — Operating cash flow -$52M (TTM)
EfficiencyCritical — ROE -19%, ROA -13.0%

Ownership (GHRS)

Insider Ownership+24.46%
Institutional Ownership+72.15%
Shares Outstanding68.64M
Float32.37M
Short % of Float+7.47%

Source: Nexqual, October 29, 2026 at 12:56 UTC.

Leadership (GHRS)

GH Research PLC is led by Velichka Valcheva M.D., M.Sc., Chief Executive Officer, per Nexqual as of October 29, 2026 at 12:56 UTC.

Chief Executive OfficerVelichka Valcheva M.D., M.Sc.
Co-Founder & Non-Executive Chairman of the BoardFlorian Schonharting M.Sc. (Econ)
Vice President of FinanceJulie Ryan F.C.A.
Chief Operating OfficerAaron Cameron

Major Backers & Investors (GHRS)

Notable institutional backers of GH Research PLC include Lynx1 Capital Management Lp, BVF Inc., RA Capital Management, L.P., according to Nexqual as of October 29, 2026 at 12:56 UTC.

Active Investors

InvestorStake
Lynx1 Capital Management Lp19.33%
BVF Inc.12.61%
RA Capital Management, L.P.11.13%
FMR, LLC8.71%
RTW Investments LP8.65%
Deep Track Capital, Lp4.86%
Fidelity4.76%
Avoro Capital Advisors LLC2.62%

Source: Nexqual, October 29, 2026 at 12:56 UTC.

Peers & Related Stocks

SymbolNamePriceChange
ORKAOruka Therapeutics, Inc.USD 95.97▲ 0.17%
LGNDLigand Pharmaceuticals IncorporUSD 318.78▲ 2.26%
IOVAIovance Biotherapeutics, Inc.USD 14.81▲ 1.58%
IONSIonis Pharmaceuticals, Inc.USD 44.9▲ 2.14%
AXSMAxsome Therapeutics, Inc.USD 143.51▲ 0.92%
ABVXAbivax SAUSD 89.84▲ 3.26%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 12:56 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt