Janux Therapeutics, Inc. (JANX) Stock Price & Analysis

Janux Therapeutics, Inc. (JANX) closed at USD 18.05 on Wednesday, October 28, 2026, up 4.58% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 17.26; the Oct 28, 2026 session ranged USD 16.89–18.07 on volume of 984,103 shares. Market capitalization is $1.10B, with a 52-week range of USD 12.12–35.34 (NGM). Source: Nexqual, retrieved October 29, 2026 at 04:05 UTC.

Also available as compact Markdown for AI agents: nexqual.com/JANX.md

Key facts (JANX)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (JANX)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$3.6M$8.6M$8.1M$10.6M$10.0M$24.0M
Operating income-$32.9M-$67.1M-$73.0M-$98.8M-$158M-$144M
Net income-$32.7M-$63.1M-$58.3M-$69.0M-$114M-$103M
EPS (diluted)-$1.39-$1.52-$1.32-$1.28-$1.83—
Free cash flow-$18.5M-$49.4M-$52.4M-$44.2M-$83.3M-$41.9M
Operating margin-905.4%-779.0%-902.9%-933.6%-1576.7%-598.1%
Net margin-898.3%-732.2%-721.2%-651.6%-1136.3%-427.5%
Revenue growth—+136.8%-6.1%+31.0%-5.6%—
Cash + short-term investments$375M$327M$344M$1.03B$967M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (JANX)

P/S 46.0x · P/B 1.2x · FCF yield -3.80% · Earnings yield -9.30%

Insider sales (SEC Form 4, open-market, last ~7 months) (JANX)

0 of 2 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-06-02Doyle Janeen NoelChief Corp. & Bus. Dev. Ofcr4,059$57K5.1%NoToo little history (no open-market trades in 2023–2025)
2026-05-11Dobek MariaVice President, Accounting2,038$29K5.9%NoToo little history (no open-market trades in 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (JANX)

Consensus Buy (mean 2.11 on a 1–5 scale), 18 analysts; mean target USD 33.81 (low 14, high 60).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-24Wolfe ResearchUpgradePeer Perform → Outperform$23
2026-08-07GuggenheimTarget loweredBuy$58 → $55

Total return (dividends reinvested) (JANX)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return-35.1%-25.9%
S&P 500 (SPY)+13.6%+79.8%
Per year-35.2%-5.8%
Volatility (annualized)89.7%99.2%
Max drawdown-64.9% (Nov 2025→Feb 2026)-79.9% (Dec 2024→Feb 2026)

JANX earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 6, 2026Quarter ended Jun 30, 2026−$0.35−$0.29Miss −20.7%-0.9%
May 7, 2026Quarter ended Mar 31, 2026−$0.39−$0.52Beat +25.0%-3.0%
Feb 26, 2026Quarter ended Dec 31, 2025−$0.51−$0.64Beat +20.3%-0.7%
Nov 6, 2025Quarter ended Sep 30, 2025−$0.39−$0.61Beat +36.1%-3.8%
Aug 7, 2025————-5.6%
May 8, 2025————-0.5%
Feb 27, 2025————+0.9%
Nov 6, 2024————-1.9%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

JANX recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 14, 2026Schedule 13G/APoint72 Asset Management, L.P., Point72 Capital Advisors, Inc.: 3.3% of shares, passive 5%+ holder (amended)
Aug 13, 2026Schedule 13G/AJANUS HENDERSON GROUP Ltd.: 0.3% of shares, passive 5%+ holder (amended)
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 6, 20268-KQuarterly results
Jul 28, 2026Schedule 13G/ABlackRock, Inc.: 6.7% of shares, passive 5%+ holder (amended)

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

JANX suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerMerck (MRK)“In addition to our wholly-owned pipeline programs, we have strategic research collaborations with Merck Sharp & Dohme Corp. (Merck) and Bristol Myers Squibb to develop product candidates directed against cancer targets.”
PartnerWuXi“License Agreement with WuXi Biologics (Hong Kong) Limited”
PartnerMerck Sharpe & Dohme“Related to the strategic research collaboration with Merck we also co-own with Merck Sharpe & Dohme LLC 1 U.S. non-provisional patent application, 1 PCT patent application, and 5 foreign patent applications which are expected to expire in 2045 absent any patent term adjustments or extensions.”
CompetitorEli Lilly (LLY)“With respect to our EGFR-TRACTr, we face competition from several targeted therapies approved by the U.S. Food and Drug Administration (FDA) to treat NSCLC, SCCHN, RCC and CRC, including, but not limited to, Genmab/Janssen's amivantamab, Roche's bevacizumab, Amgen's panitumumab, Eli Lilly/Merck KGaA's cetuximab, Bayer's regorafenib, and Eli Lilly's ramucirumab.”
CompetitorAbbVie (ABBV)“Additional competition may come from other companies developing costimulatory multispecifics, including, but not limited to AbbVie, AstraZeneca, Genmab/BioNTech, Inhibrx, Incyte/Merus, Johnson & Johnson, Chugai/Roche and Xencor.”
CompetitorJohnson & Johnson (JNJ)“Additional competition may come from other companies developing costimulatory multispecifics, including, but not limited to AbbVie, AstraZeneca, Genmab/BioNTech, Inhibrx, Incyte/Merus, Johnson & Johnson, Chugai/Roche and Xencor.”

Quoted from the company's 10-K filed Feb 26, 2026.

JANX company outlook (results filed Aug 6, 2026)

Quoted word-for-word from the SEC 8-K results press release.

JANX analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.49$-0.52+$0.03$6.4M14
Next quarter (ends Dec 2026)$-0.57$-0.61+$0.05$7.3M14
Current fiscal year (ends Dec 2026)$-1.73$-1.76+$0.03$29.4M14
Next fiscal year (ends Dec 2027)$-2.62$-2.70+$0.07$8.1M13

JANX options: expected move

Options price a move of about ±18.9% (±$3.33) by Nov 20, 2026, which includes earnings on Nov 5, 2026. Over the last 8 reports the stock moved ±2.2% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262398.1%±18.9%
Dec 18, 20265182.7%±25.0%
Jan 15, 20277990.2%±30.5%
Feb 19, 202711473.7%±33.4%
May 21, 202720578.8%±46.7%

30-day implied volatility 81.4% vs 46.1% realized over the last 30 trading days. Put/call ratio (volume) 2.51. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 04:05 UTC)

PriceUSD 18.05
Change▲ 4.58% (up)
Previous CloseUSD 17.26
OpenUSD 17.01
Day RangeUSD 16.89 – 18.07
52-Week RangeUSD 12.12 – 35.34
Volume984,103 shares
Market Cap$1.10B
ExchangeNGM

Technical Analysis (JANX)

Nexqual's technical model rates JANX "BUY" based on 4 bullish and 1 bearish signals across 127 daily candles, as of October 29, 2026 at 04:05 UTC.

Overall SignalBUY
RSI (14)58.08 (neutral)
vs SMA50Above (USD 17.59)
MACD-0.02 (negative)

Analyst Ratings (JANX)

Wall Street analysts rate JANX "Buy" based on 18 analysts, with a mean price target of USD 33.81 (range USD 14–60), per Nexqual as of October 29, 2026 at 04:05 UTC.

Consensus RatingBuy
Analyst Count18
Mean TargetUSD 33.81
High TargetUSD 60
Low TargetUSD 14
Buy / Hold / Sell16 / 1 / 1

Earnings (JANX)

Next Earnings Date2026-11-05
EPS EstimateUSD -0.49
Revenue Estimate$6.42M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.35 vs est -0.29 ▼ miss
2026-03-31USD -0.39 vs est -0.52 ▲ beat
2025-12-31USD -0.51 vs est -0.64 ▲ beat
2025-09-30USD -0.39 vs est -0.61 ▲ beat

Source: Nexqual, October 29, 2026 at 04:05 UTC.

Financials & Fundamentals (JANX)

Total Revenue$24.00M
Gross Margin+0.00%
Operating Margin-308.66%
Profit Margin+0.00%
ROE-10.70%
Debt / Equity0.02
Current Ratio16.35
Total Cash$970.91M
Total Debt$20.99M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$41.92M (-174.7% of revenue)

Source: Nexqual, October 29, 2026 at 04:05 UTC.

Financial Health Score (JANX)

Nexqual rates Janux Therapeutics, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 04:05 UTC.

GrowthWeak — Revenue -6% YoY (annual), declining
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $971M cash vs $21M debt, net cash position
Cash FlowWeak — FCF negative: -$42M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -11%, ROA -10.2% (last 4 quarters, SEC)

Ownership (JANX)

Insider Ownership+0.99%
Institutional Ownership+101.14%
Shares Outstanding61.14M
Float42.53M
Short % of Float+11.15%

Source: Nexqual, October 29, 2026 at 04:05 UTC.

Leadership (JANX)

Janux Therapeutics, Inc. is led by David Alan Campbell, President, Co-Founder, CEO & Director, per Nexqual as of October 29, 2026 at 04:05 UTC.

President, Co-Founder, CEO & DirectorDavid Alan Campbell
Chief Scientific OfficerThomas Diraimondo
Vice President of FinanceMatt Whitmire
Vice President of AccountingMaria Dobek

Major Backers & Investors (JANX)

Notable institutional backers of Janux Therapeutics, Inc. include RA Capital Management, L.P., Prosight Management, Lp, FMR, LLC, according to Nexqual as of October 29, 2026 at 04:05 UTC.

Active Investors

InvestorStake
RA Capital Management, L.P.18.3%
Prosight Management, Lp6.22%
FMR, LLC3.95%
Federated Hermes, Inc.3.85%
Point72 Asset Management, L.P.3.26%
TCG Crossover Management, LLC2.93%
Alyeska Investment Group, L.p.2.69%

Index Funds (Passive)

FundStake
BlackRock10.03%
State Street4.92%
Vanguard Group3.04%

Source: Nexqual, October 29, 2026 at 04:05 UTC.

From Janux Therapeutics, Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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IONSIonis Pharmaceuticals, Inc.USD 44.9▲ 2.14%
AXSMAxsome Therapeutics, Inc.USD 143.51▲ 0.92%
ABVXAbivax SAUSD 89.84▲ 3.26%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 04:05 UTC. This page is informational and not investment advice.

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