Lakefront Biotherapeutics NV (LKFT) Stock Price & Analysis

Lakefront Biotherapeutics NV (LKFT) closed at USD 31.4 on Thursday, October 22, 2026, up 2.68% on the day. The US market is currently closed (pre-market); this is not a live price.

The prior close was USD 30.58; the Oct 22, 2026 session ranged USD 30.55–31.53 on volume of 307,945 shares. Market capitalization is $2.06B, with a 52-week range of USD 25.68–36.24 (NMS). Source: Nexqual, retrieved October 23, 2026 at 09:23 UTC.

Also available as compact Markdown for AI agents: nexqual.com/LKFT.md

Key facts (LKFT)

Superinvestors (SEC 13F-HR, Q2 2026) (LKFT)

1 of 80 tracked investors hold LKFT. Each row is the investor's latest 13F; change is vs their prior-quarter share count.

InvestorFirm% of portfolioValueChange
David EinhornGreenlight Capital0.37%$14.5MUnchanged

Analysts (LKFT)

Consensus Hold (mean 2.67 on a 1–5 scale), 6 analysts; mean target USD 30.42 (low 21.27, high 44.03).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-09-23RBC CapitalUpgradeSector Perform → Outperform$26 → $45
2026-08-11Morgan StanleyTarget loweredEqual-Weight$30 → $26
2026-08-11RBC CapitalTarget loweredSector Perform$28 → $26

Total return (dividends reinvested) (LKFT)

1Y (from 2025-10-23)5Y (from 2021-10-18)
Total return-2.0%-38.4%
S&P 500 (SPY)+14.9%+80.3%
Per year-2.0%-9.2%
Volatility (annualized)27.9%31.2%
Max drawdown-24.7% (Jan 2026→Aug 2026)-67.5% (Apr 2022→Feb 2025)

LKFT suppliers, customers and competitors (named in its 20-F)

RelationshipCompanySentence in the filing
PartnerAlfasigma“Effective January 31, 2024, following the closing of the transaction between us and Alfasigma S.p.A. to transfer the Jyseleca® business to Alfasigma S.p.A., we assigned our rights and obligations under the filgotinib collaboration to Alfasigma S.p.A., except for our right to receive royalties from Gilead on net sales in the Gilead Territory (meaning all countries in the world other than the countries included in t…”
PartnerUSWM CT“Following our decision to initiate the wind-down of the cell therapy activities, we have notified USWM of our decision to terminate the Collaboration and Exclusive License Agreement and all ancillary agreements.”
PartnerAbbVie (ABBV)“In this role, he oversaw complex mergers, acquisitions, licensing, and collaborations, including AbbVie's landmark $63 billion acquisition of Allergan PLC and numerous high-profile partnerships with companies such as Boehringer Ingelheim and Genmab.”
PartnerLonza“As a result, we fully impaired all associated intangible assets (with a total net book value at September 30, 2025 of €131.5 million), consisting of the in-process R&D (€28.2 million related to two CAR-T product candidates, €7.5 million related to our collaboration with Pregene and €2.2 million related to other assets), the exclusive rights related to our exclusivity contract with Lonza (€51.6 million), the upfron…”

Quoted from the company's 20-F filed Mar 26, 2026.

LKFT analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$0.23$-1.31-117.6%$41.2M1
Next quarter (ends Dec 2026)$-0.17$-0.71-76.9%$106.8M2
Current fiscal year (ends Dec 2026)$-0.71$-13.24-94.6%$117.2M1
Next fiscal year (ends Dec 2027)$-1.06$-1.72-38.2%$84.6M2

Key Statistics (as of October 23, 2026 at 09:23 UTC)

PriceUSD 31.4
Change▲ 2.68% (up)
Previous CloseUSD 30.58
OpenUSD 30.62
Day RangeUSD 30.55 – 31.53
52-Week RangeUSD 25.68 – 36.24
Volume307,945 shares
Market Cap$2.06B
ExchangeNMS

Technical Analysis (LKFT)

Nexqual's technical model rates LKFT "BUY" based on 5 bullish and 2 bearish signals across 127 daily candles, as of October 23, 2026 at 09:23 UTC.

Overall SignalBUY
RSI (14)64.92 (neutral)
vs SMA50Above (USD 29.03)
MACD0.46 (positive)

Analyst Ratings (LKFT)

Wall Street analysts rate LKFT "Hold" based on 6 analysts, with a mean price target of USD 30.42 (range USD 21.27–44.03), per Nexqual as of October 23, 2026 at 09:23 UTC.

Consensus RatingHold
Analyst Count6
Mean TargetUSD 30.42
High TargetUSD 44.03
Low TargetUSD 21.27
Buy / Hold / Sell2 / 3 / 1

Earnings (LKFT)

Next Earnings Date2026-11-11
EPS EstimateUSD 0.23
Revenue Estimate$41.18M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 0.03 vs est -11.5 ▲ beat
2026-03-31USD 0.21 vs est -0.97 ▲ beat
2025-12-31USD 12.27 vs est -0.07 ▲ beat
2025-09-30USD -0.18 vs est -0.28 ▲ beat

Source: Nexqual, October 23, 2026 at 09:23 UTC.

Financials & Fundamentals (LKFT)

Total Revenue$990.57M
Revenue Growth (latest quarter, YoY)-81.50%
Gross Margin+67.61%
Operating Margin-359.30%
Profit Margin+60.23%
ROE+20.12%
Debt / Equity0
Current Ratio32.84
Total Cash$2.24B
Total Debt$6.36M

Source: Nexqual, October 23, 2026 at 09:23 UTC.

Financial Health Score (LKFT)

Nexqual rates Lakefront Biotherapeutics NV's overall financial health "Solid" across five dimensions, as of October 23, 2026 at 09:23 UTC.

GrowthStrong — Revenue +303% YoY (annual)
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — EUR 2.24B cash vs EUR 6M debt, net cash position
Cash FlowWeak — Operating cash flow -EUR 227M (TTM)
EfficiencyStrong — ROE 20%, ROA 9.9%

Ownership (LKFT)

Insider Ownership+25.45%
Institutional Ownership+23.66%
Shares Outstanding65.48M
Float461.79M
Short % of Float+8.28%

Source: Nexqual, October 23, 2026 at 09:23 UTC.

Leadership (LKFT)

Lakefront Biotherapeutics NV is led by Henry O. Gosebruch, CEO & Executive Director, per Nexqual as of October 23, 2026 at 09:23 UTC.

CEO & Executive DirectorHenry O. Gosebruch
Chief Financial OfficerAaron L. Cox
Chief Operating OfficerChristina Carlson

Major Backers & Investors (LKFT)

Notable institutional backers of Lakefront Biotherapeutics NV include Gilead Sciences Inc, Tang Capital Management, LLC, Madison Avenue Partners, LP, according to Nexqual as of October 23, 2026 at 09:23 UTC.

Active Investors

InvestorStake
Gilead Sciences Inc25.35%
Tang Capital Management, LLC5.75%
Madison Avenue Partners, LP5.23%
Prosight Management, Lp3.1%
EcoR1 Capital, LLC2.53%
Ameriprise Financial, Inc.1.93%
DME Capital Management, LP0.73%
Renaissance Technologies0.62%

Index Funds (Passive)

FundStake
Columbia Threadneedle1.7%
BlackRock0.51%

Source: Nexqual, October 23, 2026 at 09:23 UTC.

Peers & Related Stocks

SymbolNamePriceChange
BLTEBelite Bio, IncUSD 150.27▼ 1.9%
LGNDLigand Pharmaceuticals IncorporUSD 307.82▼ 2.21%
IOVAIovance Biotherapeutics, Inc.USD 14.14▼ 3.28%
PRAXPraxis Precision Medicines, IncUSD 258.92▲ 0.96%
IONSIonis Pharmaceuticals, Inc.USD 43.91▼ 0.81%
TGTXTG Therapeutics, Inc.USD 53.16▼ 0.08%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 09:23 UTC. This page is informational and not investment advice.

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