MacroGenics, Inc. (MGNX) Stock Price & Analysis

MacroGenics, Inc. (MGNX) is trading at USD 2.53, up 2.43% today, as of October 29, 2026 at 16:00 UTC (US market open; quotes may be delayed), according to Nexqual market data.

MGNX last closed at USD 2.47; today's session has ranged USD 2.43–2.59 on volume of 399,457 shares. Market capitalization is $161.16M, with a 52-week range of USD 1.29–5.08 (NMS). Source: Nexqual, retrieved October 29, 2026 at 16:06 UTC.

Also available as compact Markdown for AI agents: nexqual.com/MGNX.md

Key facts (MGNX)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (MGNX)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$77.4M$152M$58.7M$150M$150M$168M
Gross profit$74.8M$149M$58.1M$149M$150M—
Operating income-$203M-$121M-$168M-$111M-$72.8M-$40.8M
Net income-$202M-$120M-$9.1M-$67.0M-$74.6M-$14.6M
EPS (diluted)-$3.37-$1.95-$0.15-$1.07-$1.18—
Free cash flow-$150M-$90.6M-$80.0M-$72.1M-$83.0M-$65.5M
Gross margin96.6%97.8%98.9%99.4%100.0%—
Operating margin-261.9%-79.9%-286.4%-73.7%-48.7%-24.3%
Net margin-261.0%-78.8%-15.4%-44.7%-49.9%-8.7%
Revenue growth-26.2%+96.2%-61.3%+155.3%-0.3%—
Cash + short-term investments—$109M$101M$183M$57.2M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (MGNX)

P/S 1.0x · P/B 3.8x · FCF yield -40.67% · Earnings yield -9.05%

Insider sales (SEC Form 4, open-market, last ~7 months) (MGNX)

1 of 1 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-08-19Peters Jeffrey StuartSenior VP, GC, and Secretary31,105$129K100%Yes (adopted May 20, 2026)Too little history (no open-market trades in 2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (MGNX)

Consensus Buy (mean 2.43 on a 1–5 scale), 7 analysts; mean target USD 8 (low 4, high 11).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-17B. Riley SecuritiesTarget raisedBuy$9 → $11

Total return (dividends reinvested) (MGNX)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+49.7%-87.0%
S&P 500 (SPY)+13.2%+79.2%
Per year+49.8%-33.5%
Volatility (annualized)92.3%111.3%
Max drawdown-54.9% (Jun 2026→Oct 2026)-95.2% (Nov 2021→Mar 2025)

MGNX earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 13, 2026Quarter ended Jun 30, 2026$1.14$0.26Beat +338.5%+5.0%
May 13, 2026Quarter ended Mar 31, 2026−$0.58−$0.55Miss −5.5%+18.2%
Mar 9, 2026Quarter ended Dec 31, 2025−$0.22−$0.02Miss −$0.20+53.8%
Nov 12, 2025Quarter ended Sep 30, 2025$0.27−$0.50Beat +$0.77+5.3%
Aug 14, 2025————-4.8%
May 13, 2025————-2.5%
Mar 20, 2025————-8.5%
Nov 5, 2024————+13.2%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

MGNX recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 23, 20268-KOther material event
“On October 23, 2026, MacroGenics, Inc. (the "Company") issued a press release announcing interim data related to its Phase 1 study evaluating MGC026, a B7-H3-directed antibody-drug conjugate, in patients with advanced solid tumors (the "Press Release"). The interim data will be presented in a poster presentation at the European Society for Medical Oncology Congress, taking place in Madrid, Spain from October 23-27, 2026. On October 23, 2026, the Company also posted a slide presentation titled "MGC026 Clinical…”
Sep 3, 20268-K/ACurrent report
Aug 14, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 14, 2026Schedule 13G/AArmistice Capital, LLC, Steven Boyd: 7.9% of shares, passive 5%+ holder (amended)
Aug 13, 20268-KQuarterly results
Aug 3, 2026Schedule 13G/ABANK OF AMERICA CORP /DE/: 4.0% of shares, passive 5%+ holder (amended)
Jul 29, 2026Schedule 13GBlackRock, Inc.: 7.1% of shares, passive 5%+ holder
Jul 23, 20268-KOther material event
“On July 23 , 2026, MacroGenics, Inc. issued a press release providing a clinical update on its ongoing Phase 1 study of MGC026. A copy of the press release is attached to this Current Report on Form 8-K as Exhibit 99.1 and is incorporated by reference into this Item 8.01.”
Jul 20, 2026Schedule 13G/AMillennium Management LLC, Millennium Group Management LLC: 3.7% of shares, passive 5%+ holder (amended)
Jul 8, 20268-KDirector or executive officer change, or pay arrangement
“On July 1, 2026, Karen Ferrante, M.D. provided notice to the board of directors (the "Board") of MacroGenics, Inc. (the "Company") of her decision to resign from the Board, effective September 1, 2026. Dr. Ferrante's decision was for personal reasons and was not the result of any disagreement with the Company or any matter relating to the Company's operations, policies or practices. The Company thanks Dr. Ferrante for her many contributions to the Company.”
Jul 7, 20268-KCompleted an acquisition or sale of assets; Regulation FD disclosure
“Effective as of June 30, 2026, MacroGenics, Inc. (the " Company ") completed the previously announced sale (the " Closing ") of certain assets and liabilities related to its GMP manufacturing operations, including its CDMO business (the " CDMO Operations ") conducted by the Company at its manufacturing facility located at 9704 Medical Center Drive, Rockville, Maryland and related warehouse operations located at 4735 Arcadia Drive, Frederick, Maryland (excluding all research and related assets and operations of the…”

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

MGNX suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerINCYTE CORP (INCY)“In 2017, we licensed retifanlimab, a mAb targeting PD-1, to Incyte Corporation (Incyte) under a global collaboration and license agreement (Incyte License Agreement); we retain the right to develop the molecule in combination with product candidates from our pipeline.”
PartnerGILEAD SCIENCES, INC. (GILD)“We are also collaborating with Gilead Sciences, Inc. (Gilead) on the development of MGD024, a bispecific DART molecule targeting CD123 and CD3 that utilizes our next-generation T-cell engager technology, as well as two additional undisclosed pre-clinical DART and TRIDENT molecule development programs.”
PartnerSynaffix“This cleavable linker-payload is based on exatecan, a clinically validated and potent camptothecin, and is site-specifically conjugated using the GlycoConnect® technology developed by our collaboration partner, Synaffix B.V., a Lonza company (Synaffix).”
PartnerSanofi (SNY)“In April 2023, Sanofi S.A. completed its acquisition of Provention and the Company entered into a tripartite agreement with DRI and Sanofi under which it was released of any obligations under the Royalty Purchase Agreement.”
PartnerLonza“This cleavable linker-payload is based on exatecan, a clinically validated and potent camptothecin, and is site-specifically conjugated using the GlycoConnect® technology developed by our collaboration partner, Synaffix B.V., a Lonza company (Synaffix).”
PartnerEversana Life Sciences Services“In November 2024, we paid an $8.0 million amendment fee to Eversana Life Sciences Services, LLC (Eversana), our former partner that had previously commercialized MARGENZA.”
PartnerTerSera Therapeutics“In connection with the sale, we entered into an agreement with TerSera to provide manufacturing services to produce MARGENZA.”
PartnerEversana Life Science Services“Selling, general and administrative expense also includes legal and professional fees and included costs incurred under the arrangement with our commercialization partner, Eversana Life Science Services, LLC in 2023 and 2024.”

Quoted from the company's 10-K filed Mar 9, 2026.

Companies that name MGNX in their SEC reports

Relationship to MGNXCompanyFilingSentence
partnerINCYTE CORP (INCY)10-K Feb 10, 2026“In October 2017, we and MacroGenics, Inc. ("MacroGenics"), announced an exclusive global collaboration and license agreement for MacroGenics' retifanlimab (formerly INCMGA0012), a humanized monoclonal antibody targeting programmed death receptor-1 ("PD-1").”

MGNX company outlook (results filed Aug 13, 2026)

Quoted word-for-word from the SEC 8-K results press release.

MGNX analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.13$-0.31+$0.19$39.2M2
Next quarter (ends Dec 2026)$-0.35$-0.28−$0.06$19.9M1
Current fiscal year (ends Dec 2026)$-1.56$-0.67−$0.89$108.2M7
Next fiscal year (ends Dec 2027)$-1.47$-1.41−$0.05$90.6M2

MGNX options: expected move

Options price a move of about ±27.1% (±$0.67) by Nov 20, 2026, which includes earnings on Nov 12, 2026. Over the last 8 reports the stock moved ±13.9% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202622126.0%±27.1%
Jan 15, 20277899.3%±134.7%
Apr 16, 202716997.7%±60.2%

30-day implied volatility 95.3% vs 155.8% realized over the last 30 trading days. Put/call ratio (volume) —. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 16:06 UTC)

PriceUSD 2.53
Change▲ 2.43% (up)
Previous CloseUSD 2.47
OpenUSD 2.49
Day RangeUSD 2.43 – 2.59
52-Week RangeUSD 1.29 – 5.08
Volume399,457 shares
Market Cap$161.16M
ExchangeNMS

Technical Analysis (MGNX)

Nexqual's technical model rates MGNX "STRONG SELL" based on 0 bullish and 5 bearish signals across 128 daily candles, as of October 29, 2026 at 16:06 UTC.

Overall SignalSTRONG SELL
RSI (14)32.72 (neutral)
vs SMA50Below (USD 3.73)
MACD-0.36 (negative)

Analyst Ratings (MGNX)

Wall Street analysts rate MGNX "Buy" based on 7 analysts, with a mean price target of USD 8 (range USD 4–11), per Nexqual as of October 29, 2026 at 16:06 UTC.

Consensus RatingBuy
Analyst Count7
Mean TargetUSD 8
High TargetUSD 11
Low TargetUSD 4
Buy / Hold / Sell3 / 4 / 0

Earnings (MGNX)

Next Earnings Date2026-11-12
EPS EstimateUSD -0.13
Revenue Estimate$39.18M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 1.14 vs est 0.26 ▲ beat
2026-03-31USD -0.58 vs est -0.55 ▼ miss
2025-12-31USD -0.22 vs est -0.02 ▼ miss
2025-09-30USD 0.27 vs est -0.51 ▲ beat

Source: Nexqual, October 29, 2026 at 16:06 UTC.

Financials & Fundamentals (MGNX)

Total Revenue$175.14M
Revenue Growth (latest quarter, YoY)+378.00%
Gross Margin-0.74%
Operating Margin-42.19%
Profit Margin-8.33%
ROE-225.85%
Debt / Equity0.82
Current Ratio2.96
Total Cash$173.30M
Total Debt$35.09M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$65.54M (-39.1% of revenue)

Source: Nexqual, October 29, 2026 at 16:06 UTC.

Financial Health Score (MGNX)

Nexqual rates MacroGenics, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 16:06 UTC.

GrowthWeak — Revenue -0% YoY (annual), declining
ProfitabilityCritical — Gross margin -1%, operating -24% (last 12 months)
Balance SheetMixed — $173M cash vs $35M debt, net cash position
Cash FlowWeak — FCF negative: -$66M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -34%, ROA -4.2% (last 4 quarters, SEC)

Ownership (MGNX)

Insider Ownership+3.49%
Institutional Ownership+77.09%
Shares Outstanding63.70M
Float56.41M
Short % of Float+8.23%

Source: Nexqual, October 29, 2026 at 16:06 UTC.

Leadership (MGNX)

MacroGenics, Inc. is led by Eric Blasius Risser, CEO, President & Director, per Nexqual as of October 29, 2026 at 16:06 UTC.

CEO, President & DirectorEric Blasius Risser
Senior VP & CFOJames Karrels
Senior VP of Research & Chief Scientific OfficerEzio Bonvini
Vice President of Technical OperationsAraba Lamouse-Smith
Senior Vice President of Human ResourcesSteve Harig

Major Backers & Investors (MGNX)

Notable institutional backers of MacroGenics, Inc. include Armistice Capital, LLC, Renaissance Technologies, Acadian Asset Management. LLC, according to Nexqual as of October 29, 2026 at 16:06 UTC.

Active Investors

InvestorStake
Armistice Capital, LLC7.86%
Renaissance Technologies4.13%
Acadian Asset Management. LLC3.99%
Bank of America Corporation3.91%
Two Sigma Investments, LP3.87%
Millennium Management3.73%
WASATCH FUNDS TRUST-Wasatch Ultra Growth Fund2.96%
RA Capital Management, L.P.2.93%

Index Funds (Passive)

FundStake
BlackRock7.35%
Vanguard Group7.03%

Source: Nexqual, October 29, 2026 at 16:06 UTC.

From MacroGenics, Inc.'s Latest SEC 10-K Filing (filed 2026-03-09)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 16:06 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt