MacroGenics, Inc. (MGNX) Stock Price & Analysis
MacroGenics, Inc. (MGNX) is trading at USD 2.53, up 2.43% today, as of October 29, 2026 at 16:00 UTC (US market open; quotes may be delayed), according to Nexqual market data.
MGNX last closed at USD 2.47; today's session has ranged USD 2.43–2.59 on volume of 399,457 shares. Market capitalization is $161.16M, with a 52-week range of USD 1.29–5.08 (NMS). Source: Nexqual, retrieved October 29, 2026 at 16:06 UTC.
Also available as compact Markdown for AI agents: nexqual.com/MGNX.md
Key facts (MGNX)
- Last four reported quarters (through Jun 30, 2026): revenue $168M, net income -$14.6M (-8.7% margin), free cash flow -$65.5M (SEC filings).
- Insider open-market sales, last ~7 months: 1 Form 4 filings, $129K; 0 not under a Rule 10b5-1 plan ($0K); 0 by opportunistic insiders, 0 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 2.43 on a 1–5 scale) (7 analysts), mean target USD 8 (range 4–11).
- Total return with dividends: 1Y +49.7% vs S&P 500 +13.2%; 5Y -87.0% vs S&P 500 +79.2%.
- Next earnings: 2026-11-12, EPS estimate USD -0.13, revenue estimate $39.2M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (MGNX)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $77.4M | $152M | $58.7M | $150M | $150M | $168M |
| Gross profit | $74.8M | $149M | $58.1M | $149M | $150M | — |
| Operating income | -$203M | -$121M | -$168M | -$111M | -$72.8M | -$40.8M |
| Net income | -$202M | -$120M | -$9.1M | -$67.0M | -$74.6M | -$14.6M |
| EPS (diluted) | -$3.37 | -$1.95 | -$0.15 | -$1.07 | -$1.18 | — |
| Free cash flow | -$150M | -$90.6M | -$80.0M | -$72.1M | -$83.0M | -$65.5M |
| Gross margin | 96.6% | 97.8% | 98.9% | 99.4% | 100.0% | — |
| Operating margin | -261.9% | -79.9% | -286.4% | -73.7% | -48.7% | -24.3% |
| Net margin | -261.0% | -78.8% | -15.4% | -44.7% | -49.9% | -8.7% |
| Revenue growth | -26.2% | +96.2% | -61.3% | +155.3% | -0.3% | — |
| Cash + short-term investments | — | $109M | $101M | $183M | $57.2M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (MGNX)
P/S 1.0x · P/B 3.8x · FCF yield -40.67% · Earnings yield -9.05%
Insider sales (SEC Form 4, open-market, last ~7 months) (MGNX)
1 of 1 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-08-19 | Peters Jeffrey Stuart | Senior VP, GC, and Secretary | 31,105 | $129K | 100% | Yes (adopted May 20, 2026) | Too little history (no open-market trades in 2025) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (MGNX)
Consensus Buy (mean 2.43 on a 1–5 scale), 7 analysts; mean target USD 8 (low 4, high 11).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-08-17 | B. Riley Securities | Target raised | Buy | $9 → $11 |
Total return (dividends reinvested) (MGNX)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +49.7% | -87.0% |
| S&P 500 (SPY) | +13.2% | +79.2% |
| Per year | +49.8% | -33.5% |
| Volatility (annualized) | 92.3% | 111.3% |
| Max drawdown | -54.9% (Jun 2026→Oct 2026) | -95.2% (Nov 2021→Mar 2025) |
MGNX earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 13, 2026 | Quarter ended Jun 30, 2026 | $1.14 | $0.26 | Beat +338.5% | +5.0% |
| May 13, 2026 | Quarter ended Mar 31, 2026 | −$0.58 | −$0.55 | Miss −5.5% | +18.2% |
| Mar 9, 2026 | Quarter ended Dec 31, 2025 | −$0.22 | −$0.02 | Miss −$0.20 | +53.8% |
| Nov 12, 2025 | Quarter ended Sep 30, 2025 | $0.27 | −$0.50 | Beat +$0.77 | +5.3% |
| Aug 14, 2025 | — | — | — | — | -4.8% |
| May 13, 2025 | — | — | — | — | -2.5% |
| Mar 20, 2025 | — | — | — | — | -8.5% |
| Nov 5, 2024 | — | — | — | — | +13.2% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
MGNX recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Oct 23, 2026 | 8-K | Other material event “On October 23, 2026, MacroGenics, Inc. (the "Company") issued a press release announcing interim data related to its Phase 1 study evaluating MGC026, a B7-H3-directed antibody-drug conjugate, in patients with advanced solid tumors (the "Press Release"). The interim data will be presented in a poster presentation at the European Society for Medical Oncology Congress, taking place in Madrid, Spain from October 23-27, 2026. On October 23, 2026, the Company also posted a slide presentation titled "MGC026 Clinical…” |
| Sep 3, 2026 | 8-K/A | Current report |
| Aug 14, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 14, 2026 | Schedule 13G/A | Armistice Capital, LLC, Steven Boyd: 7.9% of shares, passive 5%+ holder (amended) |
| Aug 13, 2026 | 8-K | Quarterly results |
| Aug 3, 2026 | Schedule 13G/A | BANK OF AMERICA CORP /DE/: 4.0% of shares, passive 5%+ holder (amended) |
| Jul 29, 2026 | Schedule 13G | BlackRock, Inc.: 7.1% of shares, passive 5%+ holder |
| Jul 23, 2026 | 8-K | Other material event “On July 23 , 2026, MacroGenics, Inc. issued a press release providing a clinical update on its ongoing Phase 1 study of MGC026. A copy of the press release is attached to this Current Report on Form 8-K as Exhibit 99.1 and is incorporated by reference into this Item 8.01.” |
| Jul 20, 2026 | Schedule 13G/A | Millennium Management LLC, Millennium Group Management LLC: 3.7% of shares, passive 5%+ holder (amended) |
| Jul 8, 2026 | 8-K | Director or executive officer change, or pay arrangement “On July 1, 2026, Karen Ferrante, M.D. provided notice to the board of directors (the "Board") of MacroGenics, Inc. (the "Company") of her decision to resign from the Board, effective September 1, 2026. Dr. Ferrante's decision was for personal reasons and was not the result of any disagreement with the Company or any matter relating to the Company's operations, policies or practices. The Company thanks Dr. Ferrante for her many contributions to the Company.” |
| Jul 7, 2026 | 8-K | Completed an acquisition or sale of assets; Regulation FD disclosure “Effective as of June 30, 2026, MacroGenics, Inc. (the " Company ") completed the previously announced sale (the " Closing ") of certain assets and liabilities related to its GMP manufacturing operations, including its CDMO business (the " CDMO Operations ") conducted by the Company at its manufacturing facility located at 9704 Medical Center Drive, Rockville, Maryland and related warehouse operations located at 4735 Arcadia Drive, Frederick, Maryland (excluding all research and related assets and operations of the…” |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
MGNX suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | INCYTE CORP (INCY) | “In 2017, we licensed retifanlimab, a mAb targeting PD-1, to Incyte Corporation (Incyte) under a global collaboration and license agreement (Incyte License Agreement); we retain the right to develop the molecule in combination with product candidates from our pipeline.” |
| Partner | GILEAD SCIENCES, INC. (GILD) | “We are also collaborating with Gilead Sciences, Inc. (Gilead) on the development of MGD024, a bispecific DART molecule targeting CD123 and CD3 that utilizes our next-generation T-cell engager technology, as well as two additional undisclosed pre-clinical DART and TRIDENT molecule development programs.” |
| Partner | Synaffix | “This cleavable linker-payload is based on exatecan, a clinically validated and potent camptothecin, and is site-specifically conjugated using the GlycoConnect® technology developed by our collaboration partner, Synaffix B.V., a Lonza company (Synaffix).” |
| Partner | Sanofi (SNY) | “In April 2023, Sanofi S.A. completed its acquisition of Provention and the Company entered into a tripartite agreement with DRI and Sanofi under which it was released of any obligations under the Royalty Purchase Agreement.” |
| Partner | Lonza | “This cleavable linker-payload is based on exatecan, a clinically validated and potent camptothecin, and is site-specifically conjugated using the GlycoConnect® technology developed by our collaboration partner, Synaffix B.V., a Lonza company (Synaffix).” |
| Partner | Eversana Life Sciences Services | “In November 2024, we paid an $8.0 million amendment fee to Eversana Life Sciences Services, LLC (Eversana), our former partner that had previously commercialized MARGENZA.” |
| Partner | TerSera Therapeutics | “In connection with the sale, we entered into an agreement with TerSera to provide manufacturing services to produce MARGENZA.” |
| Partner | Eversana Life Science Services | “Selling, general and administrative expense also includes legal and professional fees and included costs incurred under the arrangement with our commercialization partner, Eversana Life Science Services, LLC in 2023 and 2024.” |
Quoted from the company's 10-K filed Mar 9, 2026.
Companies that name MGNX in their SEC reports
| Relationship to MGNX | Company | Filing | Sentence |
|---|---|---|---|
| partner | INCYTE CORP (INCY) | 10-K Feb 10, 2026 | “In October 2017, we and MacroGenics, Inc. ("MacroGenics"), announced an exclusive global collaboration and license agreement for MacroGenics' retifanlimab (formerly INCMGA0012), a humanized monoclonal antibody targeting programmed death receptor-1 ("PD-1").” |
MGNX company outlook (results filed Aug 13, 2026)
- “Guidance : MacroGenics anticipates that its pro forma cash, cash equivalents and marketable securities of $327 million as of June 30, 2026, plus other projected future payments from partners, will support the Company's cash runway through 2028.”
Quoted word-for-word from the SEC 8-K results press release.
MGNX analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-0.13 | $-0.31 | +$0.19 | $39.2M | 2 |
| Next quarter (ends Dec 2026) | $-0.35 | $-0.28 | −$0.06 | $19.9M | 1 |
| Current fiscal year (ends Dec 2026) | $-1.56 | $-0.67 | −$0.89 | $108.2M | 7 |
| Next fiscal year (ends Dec 2027) | $-1.47 | $-1.41 | −$0.05 | $90.6M | 2 |
MGNX options: expected move
Options price a move of about ±27.1% (±$0.67) by Nov 20, 2026, which includes earnings on Nov 12, 2026. Over the last 8 reports the stock moved ±13.9% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 22 | 126.0% | ±27.1% |
| Jan 15, 2027 | 78 | 99.3% | ±134.7% |
| Apr 16, 2027 | 169 | 97.7% | ±60.2% |
30-day implied volatility 95.3% vs 155.8% realized over the last 30 trading days. Put/call ratio (volume) —. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 29, 2026 at 16:06 UTC)
| Price | USD 2.53 |
|---|---|
| Change | ▲ 2.43% (up) |
| Previous Close | USD 2.47 |
| Open | USD 2.49 |
| Day Range | USD 2.43 – 2.59 |
| 52-Week Range | USD 1.29 – 5.08 |
| Volume | 399,457 shares |
| Market Cap | $161.16M |
| Exchange | NMS |
Technical Analysis (MGNX)
Nexqual's technical model rates MGNX "STRONG SELL" based on 0 bullish and 5 bearish signals across 128 daily candles, as of October 29, 2026 at 16:06 UTC.
| Overall Signal | STRONG SELL |
|---|---|
| RSI (14) | 32.72 (neutral) |
| vs SMA50 | Below (USD 3.73) |
| MACD | -0.36 (negative) |
Analyst Ratings (MGNX)
Wall Street analysts rate MGNX "Buy" based on 7 analysts, with a mean price target of USD 8 (range USD 4–11), per Nexqual as of October 29, 2026 at 16:06 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 7 |
| Mean Target | USD 8 |
| High Target | USD 11 |
| Low Target | USD 4 |
| Buy / Hold / Sell | 3 / 4 / 0 |
Earnings (MGNX)
| Next Earnings Date | 2026-11-12 |
|---|---|
| EPS Estimate | USD -0.13 |
| Revenue Estimate | $39.18M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD 1.14 vs est 0.26 ▲ beat |
| 2026-03-31 | USD -0.58 vs est -0.55 ▼ miss |
| 2025-12-31 | USD -0.22 vs est -0.02 ▼ miss |
| 2025-09-30 | USD 0.27 vs est -0.51 ▲ beat |
Source: Nexqual, October 29, 2026 at 16:06 UTC.
Financials & Fundamentals (MGNX)
| Total Revenue | $175.14M |
|---|---|
| Revenue Growth (latest quarter, YoY) | +378.00% |
| Gross Margin | -0.74% |
| Operating Margin | -42.19% |
| Profit Margin | -8.33% |
| ROE | -225.85% |
| Debt / Equity | 0.82 |
| Current Ratio | 2.96 |
| Total Cash | $173.30M |
| Total Debt | $35.09M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$65.54M (-39.1% of revenue) |
Source: Nexqual, October 29, 2026 at 16:06 UTC.
Financial Health Score (MGNX)
Nexqual rates MacroGenics, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 16:06 UTC.
| Growth | Weak — Revenue -0% YoY (annual), declining |
|---|---|
| Profitability | Critical — Gross margin -1%, operating -24% (last 12 months) |
| Balance Sheet | Mixed — $173M cash vs $35M debt, net cash position |
| Cash Flow | Weak — FCF negative: -$66M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE -34%, ROA -4.2% (last 4 quarters, SEC) |
Ownership (MGNX)
| Insider Ownership | +3.49% |
|---|---|
| Institutional Ownership | +77.09% |
| Shares Outstanding | 63.70M |
| Float | 56.41M |
| Short % of Float | +8.23% |
Source: Nexqual, October 29, 2026 at 16:06 UTC.
Leadership (MGNX)
MacroGenics, Inc. is led by Eric Blasius Risser, CEO, President & Director, per Nexqual as of October 29, 2026 at 16:06 UTC.
| CEO, President & Director | Eric Blasius Risser |
|---|---|
| Senior VP & CFO | James Karrels |
| Senior VP of Research & Chief Scientific Officer | Ezio Bonvini |
| Vice President of Technical Operations | Araba Lamouse-Smith |
| Senior Vice President of Human Resources | Steve Harig |
Major Backers & Investors (MGNX)
Notable institutional backers of MacroGenics, Inc. include Armistice Capital, LLC, Renaissance Technologies, Acadian Asset Management. LLC, according to Nexqual as of October 29, 2026 at 16:06 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Armistice Capital, LLC | 7.86% |
| Renaissance Technologies | 4.13% |
| Acadian Asset Management. LLC | 3.99% |
| Bank of America Corporation | 3.91% |
| Two Sigma Investments, LP | 3.87% |
| Millennium Management | 3.73% |
| WASATCH FUNDS TRUST-Wasatch Ultra Growth Fund | 2.96% |
| RA Capital Management, L.P. | 2.93% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 7.35% |
| Vanguard Group | 7.03% |
Source: Nexqual, October 29, 2026 at 16:06 UTC.
From MacroGenics, Inc.'s Latest SEC 10-K Filing (filed 2026-03-09)
Key Strengths & Strategy (as disclosed to the SEC)
- However, there is no guarantee that the applicable authorities, including the FDA in the United States, will agree with our assessment of whether such extensions should be granted, and even if granted, the length of such extensions.
- Although we take steps to protect our proprietary information and trade secrets, including through contractual means with our employees and consultants, third parties may independently develop substantially equivalent proprietary information and techniques or otherwise gain access to our trade secrets or disclose our technology.
- We generate our pipeline of product candidates from our proprietary suite of antibody technology platforms.
- DART and TRIDENT Platforms: Our Proprietary Approach to Engineer Multi-Specific Antibodies We use our DART platform to create derivatives of antibodies with the ability to bind to two distinct targets instead of a single target as with traditional mAbs.
Partnerships
- In connection with the sale, we entered into an agreement with TerSera to provide manufacturing services to produce MARGENZA.
- In June 2025, we received $70.0 million upon entering into a royalty purchase agreement with Sagard Healthcare Partners (Sagard) in exchange for a capped royalty interest on future global net sales of ZYNYZ.
Legal & Regulatory Risks (Item 1A, quoted)
- We are subject to the U.S. Foreign Corrupt Practices Act and other anti-corruption laws. If we fail to comply with these laws, we could be subject to civil or criminal penalties, other remedial measures, and legal expenses, which could adversely affect our business, results of operations and financial condition.
- Our research and development involves, and may in the future involve, the use of potentially hazardous materials and chemicals.
- We and our collaborators are subject to various healthcare laws, and our failure, or the failure of our collaborators, to comply with those laws could result in significant penalties and adversely affect our business, operations and financial condition.
- Our employees and personnel may integrate generative AI technologies to perform their work, and the disclosure and use of personal data in AI technologies is subject to various privacy laws and other privacy obligations.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| KOD | Kodiak Sciences Inc | USD 101.39 | ▲ 4.48% |
| RYTM | Rhythm Pharmaceuticals, Inc. | USD 93.07 | ▲ 1.19% |
| ORKA | Oruka Therapeutics, Inc. | USD 96.98 | ▲ 1.05% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 45.04 | ▲ 0.31% |
| AXSM | Axsome Therapeutics, Inc. | USD 144.54 | ▲ 0.72% |
| ABVX | Abivax SA | USD 90.59 | ▲ 0.83% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 16:06 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt