MeiraGTx Holdings plc (MGTX) Stock Price & Analysis

MeiraGTx Holdings plc (MGTX) is trading at USD 9.78, up 0.26% today, as of October 29, 2026 at 16:06 UTC (US market open; quotes may be delayed), according to Nexqual market data.

MGTX last closed at USD 9.75; today's session has ranged USD 9.58–9.9 on volume of 100,293 shares. Market capitalization is $938.82M, with a 52-week range of USD 6.62–15.35 (NMS). Source: Nexqual, retrieved October 29, 2026 at 16:07 UTC.

Also available as compact Markdown for AI agents: nexqual.com/MGTX.md

Key facts (MGTX)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (MGTX)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$37.7M$15.9M$14.0M$33.3M$81.4M$398M
Operating income-$72.8M-$116M-$137M-$164M-$106M$184M
Net income-$79.6M-$130M-$84.0M-$148M-$114M$79.0M
EPS (diluted)-$1.80-$2.87-$1.49-$2.12-$1.42—
Free cash flow-$56.9M-$118M-$126M-$109M-$50.2M$10.5M
Operating margin-193.0%-730.9%-977.8%-493.4%-130.2%46.3%
Net margin-211.0%-814.2%-599.5%-444.1%-140.3%19.9%
Revenue growth+142.2%-57.8%-12.0%+137.4%+144.6%—
Cash + short-term investments$138M$116M$130M$104M$65.9M—
Total debt—$71.0M$72.1M$73.2M$49.7M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (MGTX)

P/E 11.9x · P/S 2.4x · EV/EBITDA 4.6x · EV/Sales 2.3x · P/FCF 89.7x · P/B 4.3x · FCF yield 1.11% · Earnings yield 8.41% · Net cash $43.2M · EV $896M

Insider sales (SEC Form 4, open-market, last ~7 months) (MGTX)

7 of 7 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-10-20Giroux RichardCFO & COO56,000$557K5.6%Yes (adopted November 18, 2025)Too little history (no open-market trades in 2023 or 2024)
2026-10-06Naylor StuartCHIEF SCI OFCR, OPHTHALMOLOGY27,659$294K4.3%Yes (adopted December 9, 2025)Too little history (no open-market trades in 2023–2025)
2026-08-18Forbes AlexandriaPRESIDENT & CEO62,000$859K4.5%Yes (adopted November 18, 2025)Too little history (no open-market trades in 2023 or 2024)
2026-07-21Giroux RichardCFO & COO56,000$701K5.3%Yes (adopted November 18, 2025)Too little history (no open-market trades in 2023 or 2024)
2026-07-07Naylor StuartCHIEF SCI OFCR, OPHTHALMOLOGY27,659$409K4.1%Yes (adopted December 9, 2025)Too little history (no open-market trades in 2023–2025)
2026-05-19Forbes AlexandriaPRESIDENT & CEO62,000$569K4.3%Yes (adopted November 18, 2025)Too little history (no open-market trades in 2023 or 2024)
2026-04-21Giroux RichardCFO & COO56,000$572K5%Yes (adopted November 18, 2025)Too little history (no open-market trades in 2023 or 2024)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (MGTX)

Consensus Buy (mean 1.88 on a 1–5 scale), 8 analysts; mean target USD 27.75 (low 16, high 50).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-09-24Goldman SachsInitiatedNeutral$16
2026-08-14RBC CapitalTarget raisedOutperform$26 → $27
2026-07-08RBC CapitalTarget raisedOutperform$25 → $26
2026-07-08HC Wainwright & Co.ReiteratedBuy$20

Total return (dividends reinvested) (MGTX)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+9.5%-54.5%
S&P 500 (SPY)+13.2%+79.2%
Per year+9.5%-14.6%
Volatility (annualized)57.5%69.4%
Max drawdown-38.7% (Aug 2026→Oct 2026)-84.4% (Dec 2021→Oct 2023)

MGTX earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 13, 2026Quarter ended Jun 30, 2026$2.52−$0.42Beat +$2.94+4.3%
May 14, 2026Quarter ended Mar 31, 2026−$0.57−$0.45Miss −26.7%-5.7%
Mar 26, 2026Quarter ended Dec 31, 2025$0.19−$0.62Beat +$0.81+0.0%
Nov 13, 2025Quarter ended Sep 30, 2025−$0.62−$0.49Miss −26.5%-5.4%
Aug 14, 2025————-2.0%
May 13, 2025————-17.5%
Mar 13, 2025————+21.5%
Nov 13, 2024————-0.3%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

MGTX recent SEC filings (last 120 days)

FiledFormWhat it says
Sep 23, 20268-KDirector or executive officer change, or pay arrangement; Regulation FD disclosure
“On September 22, 2026, the Board of Directors (the "Board") of MeiraGTx Holdings plc (the "Company"), upon the recommendation of its Nominating and Corporate Governance Committee, appointed Alan M. Sebulsky to the Board as a Class I director, effective September 23, 2026, with a term that expires at the Company's 2028 annual meeting of shareholders when Class I directors are up for re-election and until his successor is duly elected and qualified. Mr. Sebulsky has been appointed to serve as a member of the Science…”
Aug 14, 2026Schedule 13G/ARubric Capital Management LP, David Rosen: 9.8% of shares, passive 5%+ holder (amended)
Aug 13, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 13, 20268-KQuarterly results
Jul 7, 20268-KEntered a material agreement; Ended a material agreement; New debt or off-balance-sheet obligation; Unregistered sale of shares; Regulation FD disclosure
“Royalty Note Purchase Agreement On June 30, 2026, MeiraGTx Holdings plc (the "Company") and certain of its subsidiaries entered into a Royalty Note Purchase Agreement (the "Royalty Note Purchase Agreement"), by and among MeiraGTx, LLC, as issuer, the Company and certain of its subsidiaries, as obligors (collectively, together with the Company, the "Obligors"), the purchasers party thereto (the "Purchasers") and Maverick SA LLC, as purchaser agent, an affiliate of funds managed by Oberland Capital Management LLC…”

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

MGTX suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerJohnson & Johnson (JNJ)“On January 30, 2019, we and our wholly-owned subsidiary MeiraGTx UK II Limited entered into a Collaboration, Option and License Agreement with Johnson & Johnson Innovative Medicine (formerly known as Janssen Pharmaceuticals, Inc.), as further amended by that certain First Amendment to Collaboration, Option and License Agreement, dated as of December 16, 2021 (the "Collaboration Agreement"), for, among other things…”
PartnerEli Lilly (LLY)“On November 7, 2025 (the "Effective Date"), our affiliates MeiraGTx Ocular UK Limited ("MeiraGTx Ocular"), MeiraGTx Limited and MeiraGTx UK II Limited, entered into a strategic collaboration and license agreement with Eli Lilly and Company ("Lilly") (the "Lilly Collaboration Agreement") for the research, development and commercialization of genetic medicines in and related to the area of ophthalmology.”
PartnerHologen“As part of the strategic collaboration, we also received an aggregate of 500,000 Class A shares of Hologen at a nominal price.”
PartnerMeiraGTx Neuro UK“On the Hologen Closing Date, under the Hologen Collaboration Agreement, MeiraGTx Neuro US will have received the applicable portion of the Upfront Payment in consideration for granting to Hologen Neuro and Hologen Neuro UK, as of the Hologen Closing Date and subject to the license granted by Hologen Neuro and Hologen Neuro UK back to MeiraGTx Neuro UK, exclusive, worldwide, royalty-free, fully paid-up licenses to …”
PartnerMeiraGTx UK II“In connection with entering into the Asset Purchase Agreement, we and MeiraGTx UK II Limited entered into a Termination Agreement with Johnson & Johnson Innovative Medicine on the Closing Date terminating the Collaboration Agreement.”
PartnerBofA Securities“In December 2023, we entered into an "at-the-market" sales agreement with BofA Securities, Inc., or BofA, pursuant to which we may sell from time to time, ordinary shares having an aggregate offering price of up to $100.0 million through BofA, acting as our agent.”
PartnerAMD (AMD)“The First UCLB License Agreement had also included an option to the dry AMD gene therapy program.”

Quoted from the company's 10-K filed Mar 30, 2026.

Companies that name MGTX in their SEC reports

Relationship to MGTXCompanyFilingSentence
partnerOcugen, Inc. (OCGN)10-K Mar 4, 2026“We are aware of several companies focusing on gene therapies for various ophthalmic indications including Applied Genetic Technologies Corporation, as acquired by Beacon Therapeutics, Astellas Pharma Inc., MeiraGTx Holdings plc in partnership with Janssen Pharmaceuticals, Inc., Nanoscope Therapeutics Inc., REGENXBIO Inc., Novartis AG, F.”

MGTX analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.47$-0.50+$0.03$7.0M3
Next quarter (ends Dec 2026)$-0.50$-0.27−$0.23$8.5M3
Current fiscal year (ends Dec 2026)$0.51$-1.47+$1.98$337.1M3
Next fiscal year (ends Dec 2027)$-1.52$-1.39−$0.13$66.9M4

MGTX options: expected move

Options price a move of about ±50.3% (±$4.80) by Nov 20, 2026, which includes earnings on Nov 12, 2026. Over the last 8 reports the stock moved ±7.1% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202622166.7%±50.3%
Dec 18, 202650130.7%±39.8%
Jan 15, 202778149.1%±56.6%
Apr 16, 2027169108.6%±60.2%

30-day implied volatility 95% vs 53.3% realized over the last 30 trading days. Put/call ratio (volume) 0. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 16:07 UTC)

PriceUSD 9.78
Change▲ 0.26% (up)
Previous CloseUSD 9.75
OpenUSD 9.79
Day RangeUSD 9.58 – 9.9
52-Week RangeUSD 6.62 – 15.35
Volume100,293 shares
Market Cap$938.82M
ExchangeNMS

Technical Analysis (MGTX)

Nexqual's technical model rates MGTX "STRONG SELL" based on 0 bullish and 5 bearish signals across 128 daily candles, as of October 29, 2026 at 16:07 UTC.

Overall SignalSTRONG SELL
RSI (14)39.86 (neutral)
vs SMA50Below (USD 11.82)
MACD-0.6 (negative)

Analyst Ratings (MGTX)

Wall Street analysts rate MGTX "Buy" based on 8 analysts, with a mean price target of USD 27.75 (range USD 16–50), per Nexqual as of October 29, 2026 at 16:07 UTC.

Consensus RatingBuy
Analyst Count8
Mean TargetUSD 27.75
High TargetUSD 50
Low TargetUSD 16
Buy / Hold / Sell7 / 1 / 0

Earnings (MGTX)

Next Earnings Date2026-11-12
EPS EstimateUSD -0.47
Revenue Estimate$7.02M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 2.52 vs est -0.42 ▲ beat
2026-03-31USD -0.57 vs est -0.45 ▼ miss
2025-12-31USD 0.19 vs est -0.62 ▲ beat
2025-09-30USD -0.62 vs est -0.49 ▼ miss

Source: Nexqual, October 29, 2026 at 16:07 UTC.

Financials & Fundamentals (MGTX)

Total Revenue$397.50M
Revenue Growth (latest quarter, YoY)+8608.60%
Gross Margin+97.95%
Operating Margin+76.04%
Profit Margin+19.87%
ROE+72.17%
Debt / Equity0.52
Current Ratio3.76
Total Cash$143.17M
Total Debt$112.32M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)$10.47M (2.6% of revenue)

Source: Nexqual, October 29, 2026 at 16:07 UTC.

Financial Health Score (MGTX)

Nexqual rates MeiraGTx Holdings plc's overall financial health "Strong" across five dimensions, as of October 29, 2026 at 16:07 UTC.

GrowthStrong — Revenue +145% YoY (annual)
ProfitabilityStrong — Operating margin 46%
Balance SheetStrong — $143M cash and investments vs $100M debt (Jun 2026, SEC), net cash
Cash FlowMixed — FCF $10M (last 4 quarters to Jun 2026, SEC), slim 2.6% margin
EfficiencyStrong — ROE 37%, ROA 19.9% (last 4 quarters, SEC)

Ownership (MGTX)

Insider Ownership+16.27%
Institutional Ownership+70.78%
Shares Outstanding96.04M
Float53.83M
Short % of Float+9.35%

Source: Nexqual, October 29, 2026 at 16:07 UTC.

Leadership (MGTX)

MeiraGTx Holdings plc is led by Alexandria Forbes, CEO, President & Director, per Nexqual as of October 29, 2026 at 16:07 UTC.

CEO, President & DirectorAlexandria Forbes
COO & CFORichard Brian Giroux B.A.
Chief Scientific Officer of OphthalmologyStuart Naylor
Senior Vice President of Global IntegrationChristine Elise Sheehy
Senior Vice President of Risk & Internal ControlsTim Randall

Major Backers & Investors (MGTX)

Notable institutional backers of MeiraGTx Holdings plc include Sanofi, Perceptive Advisors Llc, Rubric Capital Management LP, according to Nexqual as of October 29, 2026 at 16:07 UTC.

Active Investors

InvestorStake
Sanofi12.7%
Perceptive Advisors Llc11.23%
Rubric Capital Management LP9.47%
Johnson & Johnson6.91%
Adage Capital Partners GP L.L.C.4.58%
Opaleye Management Inc.3.7%
Millennium Management3.09%
683 Capital Management LLC2.39%

Index Funds (Passive)

FundStake
BlackRock4.95%

Source: Nexqual, October 29, 2026 at 16:07 UTC.

From MeiraGTx Holdings plc's Latest SEC 10-K Filing (filed 2026-03-30)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 16:07 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt