Nautilus Biotechnology, Inc. (NAUT) Stock Price & Analysis

Nautilus Biotechnology, Inc. (NAUT) closed at USD 2.16 on Thursday, October 15, 2026, up 0.00% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 2.16; the Oct 15, 2026 session ranged USD 1.88–2.2 on volume of 8,502,195 shares. Market capitalization is $274.87M, with a 52-week range of USD 0.84–4.31 (NCM). Source: Nexqual, retrieved October 16, 2026 at 05:20 UTC.

Also available as compact Markdown for AI agents: nexqual.com/NAUT.md

Key facts (NAUT)

Analysts (NAUT)

Consensus Buy (mean 2.00 on a 1–5 scale), 4 analysts; mean target USD 3.83 (low 3.5, high 4).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-09-29Roth CapitalInitiatedBuy$3.5
2026-09-09Leerink PartnersInitiatedOutperform$4

Total return (dividends reinvested) (NAUT)

1Y (from 2025-10-16)5Y (from 2021-10-11)
Total return+101.9%-62.2%
S&P 500 (SPY)+18.1%+85.1%
Per year+102.4%-17.6%
Volatility (annualized)117.0%78.4%
Max drawdown-78.4% (Mar 2026→Aug 2026)-89.1% (Dec 2021→Sep 2025)

Key Statistics (as of October 16, 2026 at 05:20 UTC)

PriceUSD 2.16
Change▲ 0.00% (up)
Previous CloseUSD 2.16
OpenUSD 2.07
Day RangeUSD 1.88 – 2.2
52-Week RangeUSD 0.84 – 4.31
Volume8,502,195 shares
Market Cap$274.87M
ExchangeNCM

Technical Analysis (NAUT)

Nexqual's technical model rates NAUT "STRONG BUY" based on 5 bullish and 0 bearish signals across 127 daily candles, as of October 16, 2026 at 05:20 UTC.

Overall SignalSTRONG BUY
RSI (14)69.85 (neutral)
vs SMA50Above (USD 1.18)
MACD0.3 (positive)

Analyst Ratings (NAUT)

Wall Street analysts rate NAUT "Buy" based on 4 analysts, with a mean price target of USD 3.83 (range USD 3.5–4), per Nexqual as of October 16, 2026 at 05:20 UTC.

Consensus RatingBuy
Analyst Count4
Mean TargetUSD 3.83
High TargetUSD 4
Low TargetUSD 3.5
Buy / Hold / Sell4 / 0 / 0

Earnings (NAUT)

Next Earnings Date2026-10-27
Revenue Estimate$206,250

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.11 vs est -0.14 ▲ beat
2026-03-31USD -0.12 vs est -0.15 ▲ beat
2025-12-31USD -0.11 vs est -0.14 ▲ beat
2025-09-30USD -0.11 vs est -0.15 ▲ beat

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Financials & Fundamentals (NAUT)

Total Revenue$190,000
Gross Margin+92.11%
Operating Margin-8296.32%
Profit Margin+0.00%
ROE-36.21%
Debt / Equity0.21
Current Ratio10.14
Total Cash$84.03M
Total Debt$27.82M

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Financial Health Score (NAUT)

Nexqual rates Nautilus Biotechnology, Inc.'s overall financial health "Weak" across five dimensions, as of October 16, 2026 at 05:20 UTC.

GrowthMixed — No data
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $84M cash vs $28M debt, net cash position
Cash FlowWeak — Operating cash flow -$51M (FY ended Dec 2025, 10-K)
EfficiencyCritical — ROE -36%, ROA -20.8%

Ownership (NAUT)

Insider Ownership+32.02%
Institutional Ownership+43.04%
Shares Outstanding127.26M
Float67.47M
Short % of Float+9.21%

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Leadership (NAUT)

Nautilus Biotechnology, Inc. is led by Sujal M. Patel (age 50), Co-Founder, CEO, President, Secretary & Director, per Nexqual as of October 16, 2026 at 05:20 UTC.

Co-Founder, CEO, President, Secretary & DirectorSujal M. Patel (age 50)
Co-Founder, Chief Scientist & DirectorParag Mallick (age 47)
CFO & TreasurerAnna Mowry (age 42)
Vice President of Global SalesAmber Faust
Vice President of MarketingJamie Rose Kuhar

Major Backers & Investors (NAUT)

Notable institutional backers of Nautilus Biotechnology, Inc. include Perceptive Advisors Llc, a16z Capital Management, L.L.C., Cercano Management Llc, according to Nexqual as of October 16, 2026 at 05:20 UTC.

Active Investors

InvestorStake
Perceptive Advisors Llc9.14%
a16z Capital Management, L.L.C.7.12%
Cercano Management Llc5.64%
Comprehensive Financial Management, LLC1.73%
Citadel1.49%
Acadian Asset Management. LLC0.83%
Clearstead Advisors, LLC0.7%

Index Funds (Passive)

FundStake
Vanguard Group3.95%
BlackRock3.37%
Geode Capital0.99%

Source: Nexqual, October 16, 2026 at 05:20 UTC.

Peers & Related Stocks

SymbolNamePriceChange
RYTMRhythm Pharmaceuticals, Inc.USD 87.97▲ 1.57%
BLTEBelite Bio, IncUSD 152.62▲ 0.49%
IOVAIovance Biotherapeutics, Inc.USD 14.72▲ 1.52%
PRAXPraxis Precision Medicines, IncUSD 248.24▲ 2.01%
IONSIonis Pharmaceuticals, Inc.USD 44.12▲ 4.11%
SYRESpyre Therapeutics, Inc.USD 80.1▼ 0.44%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 16, 2026 at 05:20 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt