Nektar Therapeutics (NKTR) Stock Price & Analysis

Nektar Therapeutics (NKTR) closed at USD 38.55 on Wednesday, October 28, 2026, up 1.53% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 38.55; the Oct 28, 2026 session ranged USD 37.49–38.6 on volume of 404,793 shares. Market capitalization is —, with a 52-week range of USD 33.4–109 (NCM). Source: Nexqual, retrieved October 29, 2026 at 07:23 UTC.

Also available as compact Markdown for AI agents: nexqual.com/NKTR.md

Key facts (NKTR)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (NKTR)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$102M$92.1M$90.1M$98.4M$55.2M$54.6M
Gross profit$77.0M$70.4M$56.4M$67.7M$55.2M—
Operating income-$446M-$376M-$264M-$105M-$140M-$141M
Net income-$524M-$368M-$276M-$119M-$164M-$157M
EPS (diluted)-$42.90-$29.55-$21.75-$8.68-$9.73—
Free cash flow-$428M-$310M-$193M-$177M-$209M-$234M
Gross margin75.6%76.5%62.5%68.8%100.0%—
Operating margin-437.8%-408.6%-292.6%-106.9%-253.7%-257.8%
Net margin-514.0%-400.0%-306.3%-120.9%-297.1%-287.8%
Revenue growth-33.4%-9.7%-2.1%+9.2%-43.9%—
Cash + short-term investments$734M$505M$304M$255M$246M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (NKTR)

P/S 24.1x · P/B 1.5x · FCF yield -17.78% · Earnings yield -11.94%

Insider sales (SEC Form 4, open-market, last ~7 months) (NKTR)

3 of 7 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-08-18Zalevsky JonathanChief R&D Officer186$13K1.9%NoRoutine (sold in Feb & May & Aug & Nov each year 2023–2025)
2026-08-18Robin Howard WPresident & CEO418$30K0.8%NoRoutine (sold in Feb & May & Aug & Nov each year 2023–2025)
2026-06-30Zalevsky JonathanChief R&D Officer5,681$398K36.8%Yes (adopted March 13, 2026)Routine (sold in Feb & May & Aug & Nov each year 2023–2025; this trade is outside those months)
2026-06-16…2026-06-17Robin Howard WPresident & CEO20,000$1.2M26.6%Yes (adopted March 13, 2026)Routine (sold in Feb & May & Aug & Nov each year 2023–2025; this trade is outside those months)
2026-06-15Zalevsky JonathanChief R&D Officer5,538$336K26.4%Yes (adopted March 13, 2026)Routine (sold in Feb & May & Aug & Nov each year 2023–2025; this trade is outside those months)
2026-05-19Zalevsky JonathanChief R&D Officer199$13K0.9%NoRoutine (sold in Feb & May & Aug & Nov each year 2023–2025)
2026-05-19Robin Howard WPresident & CEO444$29K0.6%NoRoutine (sold in Feb & May & Aug & Nov each year 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (NKTR)

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-12UBSInitiatedNeutral$53
2026-10-12Leerink PartnersInitiatedOutperform$130
2026-10-09BTIGReiteratedBuy$178
2026-10-09Raymond JamesInitiatedMarket Perform
2026-10-02HC Wainwright & Co.ReiteratedBuy$185
2026-09-28BTIGReiteratedBuy$178
2026-09-25BTIGReiteratedBuy$178
2026-09-23WedbushTarget loweredNeutral$80 → $50
2026-09-16BTIGReiteratedBuy$178
2026-09-09BTIGReiteratedBuy$178
2026-07-22Canaccord GenuityInitiatedBuy$153

Total return (dividends reinvested) (NKTR)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return-35.4%-83.0%
S&P 500 (SPY)+13.6%+79.8%
Per year-35.5%-29.8%
Volatility (annualized)79.9%109.1%
Max drawdown-64.3% (Apr 2026→Oct 2026)-97.1% (Dec 2021→Nov 2023)

NKTR earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 13, 2026Quarter ended Jun 30, 2026−$1.23−$1.93Beat +36.3%-4.0%
May 7, 2026Quarter ended Mar 31, 2026−$1.82−$1.56Miss −16.7%-3.8%
Mar 12, 2026Quarter ended Dec 31, 2025−$1.78−$2.47Beat +27.9%-0.1%
Nov 6, 2025Quarter ended Sep 30, 2025−$1.87−$2.61Beat +28.4%+3.2%
Aug 7, 2025————+2.7%
May 8, 2025————-3.3%
Mar 12, 2025————+0.0%
Nov 7, 2024————+0.7%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

NKTR recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 1, 20268-KRegulation FD disclosure
Sep 28, 2026Schedule 13G/ATwo Seas Capital LP, Two Seas Capital GP LLC: 9.8% of shares, passive 5%+ holder (amended)
Sep 25, 20268-KOther material event
“In August 2023, Nektar Therapeutics (the "Company") filed a complaint in the U.S. District Court for the Northern District of California (the "District Court") against Eli Lilly and Company ("Lilly") alleging, among other claims, breach of contract and breach of the implied covenant of good faith and fair dealing in connection with the license agreement governing the parties' prior collaboration for the development and commercialization of rezpegaldesleukin (the "License Agreement"). The case, Nektar Therapeutics…”
Sep 8, 20268-KRegulation FD disclosure
Aug 14, 2026Schedule 13G/ATwo Seas Capital LP, Two Seas Capital GP LLC: 9.1% of shares, passive 5%+ holder (amended)
Aug 14, 2026Schedule 13G/ABIOTECHNOLOGY VALUE FUND L P, BVF I GP LLC: 7.1% of shares, passive 5%+ holder (amended)
Aug 14, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 13, 20268-KQuarterly results
Jul 31, 2026Schedule 13GVanguard Capital Management: 5.2% of shares, passive 5%+ holder
Jul 29, 2026Schedule 13GBlackRock, Inc.: 7.8% of shares, passive 5%+ holder

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

NKTR suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
CustomerTAKEDA PHARMACEUTICAL CO LTD (TAK)“Revenue from Baxalta (a subsidiary of Takeda Pharmaceutical Company Limited), AstraZeneca, and UCB represented 45%, 37%, and 14% of our revenue, respectively, for the year ended December 31, 2025.”
CustomerBaxalta“Revenue from UCB, Baxalta, AstraZeneca, Pfizer Inc., and Roche represented 39%, 18%, 17%, 12% and 10% of our revenue, respectively, for the year ended December 31, 2024.”
CustomerPfizer (PFE)“Revenue from UCB, Baxalta, AstraZeneca, Pfizer Inc., and Roche represented 39%, 18%, 17%, 12% and 10% of our revenue, respectively, for the year ended December 31, 2024.”
PartnerEli Lilly (LLY)“Although we previously entered into a license agreement with Eli Lilly and Company (Lilly) in 2017 (the Lilly Agreement) to develop and commercialize rezpegaldesleukin, on April 23, 2023, we received from Lilly a notice of at-will termination of the Lilly Agreement, and on April 27, 2023, we announced that we would be regaining full rights to rezpegaldesleukin.”
PartnerBiolojic Design“We are currently conducting Investigational New Drug (IND) enabling studies for this program, after having exercised an option to gain an exclusive license to specified agonistic antibodies and other materials that were developed pursuant to a research collaboration and license option agreement we entered into with Biolojic Design, Ltd. in 2021.”
PartnerMerck (MRK)“We are continuing our oncology clinical collaboration with Merck KGaA to evaluate the maintenance regimen of NKTR-255 in combination with avelumab, a PD-L1 inhibitor, in patients with locally advanced or metastatic urothelial carcinoma in the Phase II JAVELIN Bladder Medley study.”
PartnerTCG Crossover Fund II“On March 4, 2024, we entered into a Securities Purchase Agreement with TCG Crossover Fund II, L.P. (TCG), pursuant to which we issued a pre-funded warrant (the TCG Pre-funded Warrant) to TCG to purchase 1,666,667 shares of Nektar's common stock for gross proceeds of $30.0 million (or a purchase price of $18.00 per share of common stock that can be issued upon exercise of the TCG Pre-funded Warrant).”
PartnerBTIG“On November 12, 2025, we also entered into the November 2025 ATM Sales Agreement with Piper Sandler & Co. and BTIG, LLC, relating to the sale of our common stock having an aggregate offering price of up to $110.0 million in an "at-the-market" offering.”

Quoted from the company's 10-K filed Mar 13, 2026.

NKTR customer concentration

In the period ended Dec 31, 2025, 3 direct customers each accounted for at least 10% (45%, 37%, 14%) of revenue, per the company's 10-K filed Mar 13, 2026. The company does not name them.

NKTR company outlook (results filed Aug 13, 2026)

Quoted word-for-word from the SEC 8-K results press release.

NKTR analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-2.07$-2.14+$0.07$10.4M15
Next quarter (ends Dec 2026)$-2.76$-2.58−$0.17$10.5M15
Current fiscal year (ends Dec 2026)$-8.08$-9.01+$0.93$41.8M15
Next fiscal year (ends Dec 2027)$-10.50$-10.85+$0.34$53.4M15

NKTR options: expected move

Options price a move of about ±15.4% (±$5.90) by Nov 20, 2026, which includes earnings on Nov 12, 2026. Over the last 8 reports the stock moved ±2.2% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262377.0%±15.4%
Dec 18, 20265171.4%±21.1%
Jan 15, 20277962.9%±23.1%
Feb 19, 202711472.3%±32.6%
Mar 19, 202714278.1%±39.3%
Apr 16, 202717079.3%±43.4%
May 21, 202720578.6%±47.1%

30-day implied volatility 73.4% vs 92.3% realized over the last 30 trading days. Put/call ratio (volume) 0.05. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 07:23 UTC)

PriceUSD 38.55
Change▲ 1.53% (up)
Previous CloseUSD 38.55
OpenUSD 38.55
Day RangeUSD 37.49 – 38.6
52-Week RangeUSD 33.4 – 109
Volume404,793 shares
Market Cap—
ExchangeNCM

Technical Analysis (NKTR)

Nexqual's technical model rates NKTR "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 29, 2026 at 07:23 UTC.

Overall SignalSTRONG SELL
RSI (14)31.46 (neutral)
vs SMA50Below (USD 57.14)
MACD-5.46 (negative)

Earnings (NKTR)

Next Earnings Date2026-11-12
EPS EstimateUSD -2.11
Revenue Estimate$10.40M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -1.23 vs est -1.93 ▲ beat
2026-03-31USD -1.82 vs est -1.56 ▼ miss
2025-12-31USD -1.78 vs est -2.47 ▲ beat
2025-09-30USD -1.87 vs est -2.61 ▲ beat

Source: Nexqual, October 29, 2026 at 07:23 UTC.

Financials & Fundamentals (NKTR)

Total Revenue$54.59M
Revenue Growth (latest quarter, YoY)-9.30%
Gross Margin+100.00%
Operating Margin-412.23%
Profit Margin-287.84%
ROE-35.76%
Debt / Equity0.15
Current Ratio10.42
Total Cash$684.34M
Total Debt$135.93M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$234.03M (-428.7% of revenue)

Source: Nexqual, October 29, 2026 at 07:23 UTC.

Financial Health Score (NKTR)

Nexqual rates Nektar Therapeutics's overall financial health "Weak" across five dimensions, as of October 29, 2026 at 07:23 UTC.

GrowthCritical — Revenue -44% YoY (annual), sharp decline
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $684M cash vs $136M debt, net cash position
Cash FlowWeak — FCF negative: -$234M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -17%, ROA -14.3% (last 4 quarters, SEC)

Ownership (NKTR)

Insider Ownership+0.38%
Institutional Ownership+107.20%
Shares Outstanding34.14M
Float28.28M
Short % of Float+22.59%

Source: Nexqual, October 29, 2026 at 07:23 UTC.

From Nektar Therapeutics's Latest SEC 10-K Filing (filed 2026-03-13)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 07:23 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt