Ocular Therapeutix, Inc. (OCUL) Stock Price & Analysis
Ocular Therapeutix, Inc. (OCUL) closed at USD 6.61 on Thursday, October 22, 2026, up 2.01% on the day. The US market is currently closed (pre-market); this is not a live price.
The prior close was USD 6.48; the Oct 22, 2026 session ranged USD 6.4–6.67 on volume of 2,145,005 shares. Market capitalization is $1.45B, with a 52-week range of USD 6–16.44 (NGM). Source: Nexqual, retrieved October 23, 2026 at 10:31 UTC.
Also available as compact Markdown for AI agents: nexqual.com/OCUL.md
Key facts (OCUL)
- Last four reported quarters (through Jun 30, 2026): revenue $52.1M, net income -$301M (-579.1% margin), free cash flow -$255M (SEC filings).
- Insider open-market sales, last ~7 months: 13 Form 4 filings, $928K; 1 not under a Rule 10b5-1 plan ($11K); 0 by opportunistic insiders, 1 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 1.67 on a 1–5 scale) (12 analysts), mean target USD 26 (range 14–34).
- Total return with dividends: 1Y -42.2% vs S&P 500 +14.9%; 5Y -4.3% vs S&P 500 +80.3%.
- Next earnings: 2026-11-04, EPS estimate USD -0.35, revenue estimate $14.3M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (OCUL)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $43.5M | $51.5M | $58.4M | $63.7M | $52.0M | $52.1M |
| Gross profit | $39.1M | $47.0M | $53.2M | $58.1M | $45.4M | — |
| Operating income | -$78.0M | -$78.7M | -$82.4M | -$172M | -$270M | -$314M |
| Net income | -$6.6M | -$71.0M | -$80.7M | -$194M | -$266M | -$301M |
| EPS (diluted) | -$0.98 | -$0.97 | -$1.02 | -$1.22 | -$1.42 | — |
| Free cash flow | -$66.7M | -$63.3M | -$76.3M | -$136M | -$217M | -$255M |
| Gross margin | 89.9% | 91.2% | 91.0% | 91.2% | 87.3% | — |
| Operating margin | -179.3% | -152.7% | -141.0% | -269.6% | -519.8% | -603.0% |
| Net margin | -15.1% | -138.0% | -138.1% | -303.7% | -511.9% | -579.1% |
| Revenue growth | +150.1% | +18.3% | +13.5% | +9.0% | -18.5% | — |
| Cash + short-term investments | $164M | $102M | $196M | $392M | $737M | — |
| Total debt | $26.4M | $28.7M | $9.1M | $68.5M | $71.3M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (OCUL)
P/S 27.9x · EV/Sales 17.8x · P/B 2.8x · FCF yield -17.57% · Earnings yield -20.77% · Net cash $526M · EV $926M
Insider sales (SEC Form 4, open-market, last ~7 months) (OCUL)
12 of 13 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-10-08 | Anderman Todd | Chief Legal Officer | 11,984 | $87K | 7.9% | Yes (adopted October 7, 2024) | Too little history (no open-market trades in 2023 or 2024) |
| 2026-10-02 | Kaiser Peter | Chief Development Officer | 9,990 | $70K | 3.8% | Yes (adopted April 9, 2024) | Too little history (no open-market trades in 2023) |
| 2026-10-02 | Heier Jeffrey S. | Chief Scientific Officer | 10,869 | $77K | 3.4% | Yes (adopted April 9, 2024) | Too little history (no open-market trades in 2023) |
| 2026-08-31 | Notman Donald | Chief Operating Officer | 1,099 | $11K | 0.3% | No | Routine (sold in Feb each year 2023–2025; this trade is outside those months) |
| 2026-08-24 | Kaiser Peter | Chief Development Officer | 3,035 | $33K | 1.1% | Yes (adopted April 9, 2024) | Too little history (no open-market trades in 2023) |
| 2026-08-24 | Nayak Sanjay | Chief Strategy Officer | 1,897 | $20K | 0.6% | Yes (adopted February 21, 2024) | Too little history (no open-market trades in 2023) |
| 2026-08-24 | Heier Jeffrey S. | Chief Scientific Officer | 3,296 | $36K | 1% | Yes (adopted April 9, 2024) | Too little history (no open-market trades in 2023) |
| 2026-08-24 | Dugel Pravin | See Remarks | 21,649 | $233K | 0.7% | Yes (adopted February 21, 2024) | Too little history (no open-market trades in 2023) |
| 2026-06-03 | Waheed Nadia | Chief Medical Officer | 14,828 | $123K | 4.7% | Yes (adopted June 1, 2024) | Too little history (no open-market trades in 2023 or 2024) |
| 2026-05-26 | Dugel Pravin | See Remarks | 21,156 | $173K | 0.6% | Yes (adopted February 21, 2024) | Too little history (no open-market trades in 2023) |
| 2026-05-26 | Kaiser Peter | Chief Development Officer | 2,967 | $24K | 1.1% | Yes (adopted April 9, 2024) | Too little history (no open-market trades in 2023) |
| 2026-05-26 | Heier Jeffrey S. | Chief Scientific Officer | 3,018 | $25K | 0.9% | Yes (adopted April 9, 2024) | Too little history (no open-market trades in 2023) |
| 2026-05-26 | Nayak Sanjay | Chief Strategy Officer | 1,858 | $15K | 0.6% | Yes (adopted February 21, 2024) | Too little history (no open-market trades in 2023) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (OCUL)
Consensus Buy (mean 1.67 on a 1–5 scale), 12 analysts; mean target USD 26 (low 14, high 34).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-19 | Needham | Reiterated | Buy | $18 |
| 2026-10-12 | UBS | Initiated | Buy | $14 |
| 2026-10-02 | Chardan Capital | Maintained | Buy | $23 |
| 2026-09-29 | Needham | Reiterated | Buy | $18 |
| 2026-09-16 | Chardan Capital | Maintained | Buy | $23 |
| 2026-09-16 | HC Wainwright & Co. | Reiterated | Buy | $25 |
| 2026-08-04 | Chardan Capital | Maintained | Buy | $23 |
| 2026-06-25 | Chardan Capital | Target raised | Buy | $21 → $23 |
Total return (dividends reinvested) (OCUL)
| 1Y (from 2025-10-23) | 5Y (from 2021-10-18) | |
|---|---|---|
| Total return | -42.2% | -4.3% |
| S&P 500 (SPY) | +14.9% | +80.3% |
| Per year | -42.3% | -0.9% |
| Volatility (annualized) | 74.0% | 76.6% |
| Max drawdown | -61.0% (Dec 2025→Oct 2026) | -71.7% (Jun 2023→Nov 2023) |
OCUL suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | AffaMed Therapeutics | “We hold worldwide exclusive commercial rights to the core technology underlying all of our product candidates in development and have not granted commercial rights to any marketing partners other than a license agreement and collaboration with AffaMed Therapeutics Limited, or AffaMed, for the development and commercialization of DEXTENZA and OTX-TIC in certain geographies in Asia agreed to between the parties.” |
| Partner | Incept | “In January 2012, we entered into an amended and restated license agreement, which we refer to as either the Prior Agreement or Original License, with Incept under which we hold an exclusive, worldwide, perpetual, irrevocable license under specified patents and technology owned or controlled by Incept to make, have made, use, offer for sale, sell, sublicense, have sublicensed, offer for sublicense and import, produ…” |
| Partner | Barings Finance | “For the year ended December 31, 2023, our interest-bearing debt included the Barings Credit Facility (from August 2, 2023), the Convertible Notes, and our obligations under a credit and security agreement with MidCap Financial Trust, as administrative agent, and other lenders that we entered into in 2014, or, as amended, the MidCap Credit Agreement, establishing a credit facility, or the MidCap Credit Facility ($2…” |
| Competitor | AMD (AMD) | “In wet AMD and diabetic retinal disease, AXPAXLI will compete with anti-VEGF compounds administered in their current formulation and prescribed for the treatment of wet AMD as these agents can in some instances deliver more than one or two months of therapeutic effect, as well as products based on gene therapy, if such products are approved.” |
Quoted from the company's 10-K filed Feb 5, 2026.
Companies that name OCUL in their SEC reports
| Relationship to OCUL | Company | Filing | Sentence |
|---|---|---|---|
| partner | EyePoint, Inc. (EYPT) | 10-K Mar 5, 2026 | “In August 2025, Ocular Therapeutix announced it received a SPA agreement with the FDA for its Phase 3 HELIOS-2 trial for AXPAXLI in NPDR.” |
OCUL company outlook (results filed Aug 3, 2026)
- “In a new post-hoc analysis of SOL-1 data applying the SOL-R rescue criteria of >5 ETDRS letter loss and ≥75 µm CSFT increase from baseline, we estimate a treatment burden reduction of up to 72% as compared to a projected on-label dosing regimen of aflibercept (2 mg) over 60 weeks.”
- “Post-hoc Analysis of SOL-1 (Phase 3, wet AMD) demonstrates up to an estimated 72% reduction in treatment burden over 60 weeks with AXPAXLI relative to a projected on-label dosing regimen of aflibercept (2 mg) every 8 weeks.”
- “The total estimated mean injection burden with AXPAXLI represents a 72% reduction counting from the first screening visit at Week -8 excluding loading doses and a 56% reduction when loading doses are included, as compared to a projected on-label dosing regimen of aflibercept (2 mg) with no rescues. ·”
- “Following these changes, topline SOL-R results are now expected in the first quarter of 2028.”
Quoted word-for-word from the SEC 8-K results press release.
OCUL analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-0.35 | $-0.39 | -8.4% | $14.3M | 6 |
| Next quarter (ends Dec 2026) | $-0.38 | $-0.41 | -6.7% | $14.2M | 6 |
| Current fiscal year (ends Dec 2026) | $-1.44 | $-1.55 | -7.0% | $52.8M | 5 |
| Next fiscal year (ends Dec 2027) | $-1.48 | $-1.54 | -3.7% | $102.0M | 6 |
OCUL options: expected move
Options price a move of about ±17.0% (±$1.13) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±7.6% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 28 | 62.5% | ±17.0% |
| Dec 18, 2026 | 56 | 88.3% | ±24.6% |
| Jan 15, 2027 | 84 | 62.6% | ±25.4% |
| Mar 19, 2027 | 147 | 72.0% | ±37.1% |
| Jun 17, 2027 | 237 | 105.4% | ±67.3% |
30-day implied volatility 71% vs 86.5% realized over the last 30 trading days. Put/call ratio (volume) 0.08. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 23, 2026 at 10:31 UTC)
| Price | USD 6.61 |
|---|---|
| Change | ▲ 2.01% (up) |
| Previous Close | USD 6.48 |
| Open | USD 6.42 |
| Day Range | USD 6.4 – 6.67 |
| 52-Week Range | USD 6 – 16.44 |
| Volume | 2,145,005 shares |
| Market Cap | $1.45B |
| Exchange | NGM |
Technical Analysis (OCUL)
Nexqual's technical model rates OCUL "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 23, 2026 at 10:31 UTC.
| Overall Signal | STRONG SELL |
|---|---|
| RSI (14) | 33.17 (neutral) |
| vs SMA50 | Below (USD 9.28) |
| MACD | -0.75 (negative) |
Analyst Ratings (OCUL)
Wall Street analysts rate OCUL "Buy" based on 12 analysts, with a mean price target of USD 26 (range USD 14–34), per Nexqual as of October 23, 2026 at 10:31 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 12 |
| Mean Target | USD 26 |
| High Target | USD 34 |
| Low Target | USD 14 |
| Buy / Hold / Sell | 12 / 0 / 0 |
Earnings (OCUL)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD -0.35 |
| Revenue Estimate | $14.30M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -0.35 vs est -0.39 ▲ beat |
| 2026-03-31 | USD -0.4 vs est -0.32 ▼ miss |
| 2025-12-31 | USD -0.29 vs est -0.34 ▲ beat |
| 2025-09-30 | USD -0.38 vs est -0.35 ▼ miss |
Source: Nexqual, October 23, 2026 at 10:31 UTC.
Financials & Fundamentals (OCUL)
| Total Revenue | $52.05M |
|---|---|
| Revenue Growth (latest quarter, YoY) | +0.10% |
| Gross Margin | +0.00% |
| Operating Margin | -609.34% |
| Profit Margin | +0.00% |
| ROE | -72.99% |
| Debt / Equity | 0.15 |
| Current Ratio | 13.11 |
| Total Cash | $598.64M |
| Total Debt | $79.38M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$255.10M (-490.1% of revenue) |
Source: Nexqual, October 23, 2026 at 10:31 UTC.
Financial Health Score (OCUL)
Nexqual rates Ocular Therapeutix, Inc.'s overall financial health "Weak" across five dimensions, as of October 23, 2026 at 10:31 UTC.
| Growth | Critical — Revenue -18% YoY (annual), sharp decline |
|---|---|
| Profitability | Critical — Heavily loss-making — early-stage company |
| Balance Sheet | Strong — $599M cash and investments vs $73M debt (Jun 2026, SEC), net cash |
| Cash Flow | Weak — FCF negative: -$255M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE -73%, ROA -35.0% |
Ownership (OCUL)
| Insider Ownership | +0.91% |
|---|---|
| Institutional Ownership | +95.24% |
| Shares Outstanding | 219.62M |
| Float | 184.69M |
| Short % of Float | +15.81% |
Source: Nexqual, October 23, 2026 at 10:31 UTC.
Leadership (OCUL)
Ocular Therapeutix, Inc. is led by Pravin U. Dugel, Executive Chairman, President & CEO, per Nexqual as of October 23, 2026 at 10:31 UTC.
| Executive Chairman, President & CEO | Pravin U. Dugel |
|---|---|
| Chief Operating Officer (Leave of Absence) | Donald Notman |
Major Backers & Investors (OCUL)
Notable institutional backers of Ocular Therapeutix, Inc. include FMR, LLC, Deep Track Capital, Lp, Fidelity, according to Nexqual as of October 23, 2026 at 10:31 UTC.
Active Investors
| Investor | Stake |
|---|---|
| FMR, LLC | 14.96% |
| Deep Track Capital, Lp | 8.96% |
| Fidelity | 7.87% |
| Avoro Capital Advisors LLC | 5.71% |
| Summer Road LLC | 5.56% |
| Venrock Adviser, LLC | 4.71% |
| Price (T.Rowe) Associates Inc | 3.47% |
| Logos Global Management LP | 2.41% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 8.82% |
| Vanguard Group | 4.02% |
Source: Nexqual, October 23, 2026 at 10:31 UTC.
From Ocular Therapeutix, Inc.'s Latest SEC 10-K Filing (filed 2026-02-05)
Key Strengths & Strategy (as disclosed to the SEC)
- AXPAXLI is seeking to address segments of the exudative retinal diseases market, which in the aggregate is estimated to include up to 8.3 million patients in the United States by 2030 and accounted for approximately $9.4 billion in U.S. annual estimated revenues in 2025, according to the Market Scope 2025 Exudative Retinal Disease Pharmaceuticals Report, published in October 2025, or the Market Scope 2025 Retina Report.
- According to the Market Scope 2025 Retina Report, there were approximately 14.8 million people globally and 1.7 million people in the United States who suffered from wet AMD in 2025, and this population is expected to grow at a 3.0% and 3.3% compound annual growth rate, or CAGR, respectively, through 2030.
- In a written Type C response received in August 2024, and a subsequent written response received in December 2024, the FDA agreed that the SOL-R repeat dosing wet AMD trial, with a primary endpoint at Week 56, should be appropriate as an adequate and well-controlled trial in support of a potential NDA and product label for AXPAXLI for the treatment of wet AMD.
- At the time, the FDA also noted that the use of one superiority trial and one non-inferiority trial is generally acceptable as the basis of an eventual NDA in wet AMD.
Partnerships
- We are conducting the SOL-1 trial in accordance with a SPA agreement with the FDA.
- We hold worldwide exclusive commercial rights to the core technology underlying all of our product candidates in development and have not granted commercial rights to any marketing partners other than a license agreement and collaboration with AffaMed Therapeutics Limited, or AffaMed, for the development and commercialization of DEXTENZA and OTX-TIC in certain geographies in Asia agreed to between the parties.
Legal & Regulatory Risks (Item 1A, quoted)
- Changes in tax laws or in their implementation or interpretation could adversely affect our business and financial condition.
- Product liability lawsuits against us could cause us to incur substantial liabilities and to limit commercialization of any products that we develop.
- Any manufacturing defect or error discovered after products have been produced and distributed could result in significant consequences, including costly recall procedures, re-stocking costs, damage to our reputation and potential for product liability claims.
- We may become involved in lawsuits to protect or enforce our licensed and owned patents or other intellectual property, which could be expensive, time-consuming and unsuccessful.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
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| PRAX | Praxis Precision Medicines, Inc | USD 258.92 | ▲ 0.96% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 43.91 | ▼ 0.81% |
| ABVX | Abivax SA | USD 90.23 | ▼ 3.49% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 10:31 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt