Relay Therapeutics, Inc. (RLAY) Stock Price & Analysis

Relay Therapeutics, Inc. (RLAY) closed at USD 19.69 on Wednesday, October 28, 2026, up 4.51% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 18.84; the Oct 28, 2026 session ranged USD 18.6–19.71 on volume of 2,807,593 shares. Market capitalization is $4.31B, with a 52-week range of USD 5.95–21.27 (NGM). Source: Nexqual, retrieved October 29, 2026 at 07:08 UTC.

Also available as compact Markdown for AI agents: nexqual.com/RLAY.md

Key facts (RLAY)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (RLAY)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$3.0M$1.4M$25.5M$10.0M$15.4M$10.3M
Operating income-$365M-$299M-$373M-$372M-$303M-$310M
Net income-$364M-$291M-$342M-$338M-$276M-$286M
EPS (diluted)-$3.82-$2.59-$2.79-$2.36-$1.61—
Free cash flow-$77.9M-$239M-$304M-$251M-$236M—
Operating margin-12040.2%-21670.9%-1460.1%-3722.1%-1971.6%-2999.4%
Net margin-12012.9%-21036.1%-1338.7%-3374.7%-1800.6%-2763.6%
Revenue growth-96.3%-54.4%+1749.8%-60.8%+53.4%—
Cash + short-term investments$280M$152M$144M$124M$84.0M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (RLAY)

P/S 416.9x · P/B 4.8x · Earnings yield -6.63%

Insider sales (SEC Form 4, open-market, last ~7 months) (RLAY)

15 of 22 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-10-07Patel SanjivPresident and CEO48,199$872K3.4%Yes (adopted October 30, 2025)Opportunistic (traded every year 2023–2025, no repeating month)
2026-10-06Catinazzo ThomasChief Financial Officer17,717$329K14.4%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)
2026-09-08Bergstrom Donald APresident, R&D8,530$162K2.1%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-09-08Catinazzo ThomasChief Financial Officer17,717$336K12.6%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-09-08Patel SanjivPresident and CEO48,199$913K3.3%Yes (adopted October 30, 2025)Opportunistic (traded every year 2023–2025, no repeating month)
2026-08-26Rahmer PeterSee remarks4,508$90K2%Yes (adopted October 31, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-08-25Svf Pauling (cayman) Ltd6,000,000$116M21.5%NoToo little history (no open-market trades in 2023–2025)
2026-08-17Patel SanjivPresident and CEO48,199$980K3.2%Yes (adopted October 30, 2025)Opportunistic (traded every year 2023–2025, no repeating month)
2026-08-14Catinazzo ThomasChief Financial Officer17,717$350K11.2%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-07-28Catinazzo ThomasChief Financial Officer1,459$27K0.9%NoRoutine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)
2026-07-28Rahmer PeterSee remarks748$14K0.3%NoRoutine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)
2026-07-28Bergstrom Donald APresident, R&D2,237$42K0.5%NoRoutine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)
2026-07-07Patel SanjivPresident and CEO48,199$944K3.1%Yes (adopted October 30, 2025)Opportunistic (traded every year 2023–2025, no repeating month)
2026-07-06Bergstrom Donald APresident, R&D8,660$162K2.1%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)
2026-07-06Catinazzo ThomasChief Financial Officer17,717$331K10%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)
2026-06-30Rahmer PeterSee remarks50,000$955K17.9%Yes (adopted October 31, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-06-22Catinazzo ThomasChief Financial Officer187,163$3.2M51.3%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-06-22Bergstrom Donald APresident, R&D93,456$1.6M18.3%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-05-14Catinazzo ThomasChief Financial Officer17,717$228K8.3%Yes (adopted October 30, 2025)Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months)
2026-04-28Catinazzo ThomasChief Financial Officer972$14K0.5%NoRoutine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (RLAY)

Consensus Buy (mean 1.77 on a 1–5 scale), 13 analysts; mean target USD 27.58 (low 20, high 32).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-20HC Wainwright & Co.Target raisedBuy$28 → $29
2026-08-14JP MorganTarget raisedOverweight$28 → $31
2026-08-10CitizensTarget raisedMarket Outperform$21 → $26
2026-08-07BarclaysTarget raisedOverweight$27 → $30
2026-07-21Goldman SachsTarget raisedBuy$22 → $31
2026-07-16Canaccord GenuityInitiatedBuy$29
2026-07-08JP MorganInitiatedOverweight$28

Total return (dividends reinvested) (RLAY)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+169.4%-40.8%
S&P 500 (SPY)+13.6%+79.8%
Per year+170.3%-9.9%
Volatility (annualized)63.0%71.5%
Max drawdown-28.1% (Apr 2026→May 2026)-94.4% (Nov 2021→Mar 2025)

RLAY earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
—Quarter ended Jun 30, 2026−$0.41−$0.39Miss −5.1%—
—Quarter ended Mar 31, 2026−$0.41−$0.36Miss −13.9%—
—Quarter ended Dec 31, 2025−$0.31−$0.40Beat +22.5%—
—Quarter ended Sep 30, 2025−$0.43−$0.42Miss −2.4%—

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

RLAY recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 14, 2026Schedule 13G/ACommodore Capital LP, Commodore Capital Master LP: 5.5% of shares, passive 5%+ holder (amended)
Aug 10, 2026Schedule 13G/APerceptive Advisors LLC, Joseph Edelman: 6.4% of shares, passive 5%+ holder (amended)
Aug 7, 2026Schedule 13G/AFMR LLC, Abigail P. Johnson: 10.0% of shares, passive 5%+ holder (amended)
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 6, 20268-KEntered a material agreement; Quarterly results
“Relay Therapeutics, Inc. (the "Company") previously entered into a common stock sales agreement (the "Original Sales Agreement"), dated August 6, 2024, with TD Securities (USA) LLC ("TD Cowen" or the "Sales Agent"), relating to shares of the Company's common stock, par value $0.001 per share (the "Common Stock"), having an aggregate offering price of up to $250,000,000, through TD Cowen. Pursuant to the Original Sales Agreement, the sale and issuance of the shares under the Original Sales Agreement were made…”
Aug 6, 2026Schedule 13GFMR LLC, Abigail P. Johnson: 9.4% of shares, passive 5%+ holder

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

RLAY suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
CustomerCompany and Genentech“On December 11, 2020, we entered into a Collaboration and License Agreement with Genentech, Inc. and F.”
PartnerElevar Therapeutics“Additionally, in December 2024, we entered into an exclusive global licensing agreement, or the Elevar Agreement, with Elevar Therapeutics, Inc., or Elevar, pursuant to which Elevar was granted global development and commercialization”
PartnerPfizer (PFE)“For example, in June 2024, we entered into a global clinical trial collaboration with Pfizer for the development of zovegalisib in combination with fulvestrant and atirmociclib, Pfizer's investigative selective-CDK4 inhibitor, in patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.”
PartnerZebiAI Therapeutics“Change in fair value of our contingent consideration liability under the Merger Agreement with ZebiAI was $0 for the year ended December 31, 2025 compared to a decrease of $13.2 million for the year ended December 31, 2024.”
PartnerCowen and Company“In August 2021, we entered into the 2021 Sales Agreement with Cowen, pursuant to which we could offer and sell shares of our common stock having aggregate gross proceeds of up to $300.0 million from time to time in "at-the-market" offerings through Cowen, as our sales agent.”

Quoted from the company's 10-K filed Feb 26, 2026.

RLAY analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.40$-0.39−$0.01$1.6M11
Next quarter (ends Dec 2026)$-0.38$-0.36−$0.02$7.8M11
Current fiscal year (ends Dec 2026)$-1.61$-1.53−$0.09$11.2M11
Next fiscal year (ends Dec 2027)$-1.63$-1.64+$0.01$17.9M11

Key Statistics (as of October 29, 2026 at 07:08 UTC)

PriceUSD 19.69
Change▲ 4.51% (up)
Previous CloseUSD 18.84
OpenUSD 18.62
Day RangeUSD 18.6 – 19.71
52-Week RangeUSD 5.95 – 21.27
Volume2,807,593 shares
Market Cap$4.31B
ExchangeNGM

Technical Analysis (RLAY)

Nexqual's technical model rates RLAY "BUY" based on 5 bullish and 1 bearish signals across 127 daily candles, as of October 29, 2026 at 07:08 UTC.

Overall SignalBUY
RSI (14)60.67 (neutral)
vs SMA50Above (USD 18.57)
MACD0.07 (positive)

Analyst Ratings (RLAY)

Wall Street analysts rate RLAY "Buy" based on 13 analysts, with a mean price target of USD 27.58 (range USD 20–32), per Nexqual as of October 29, 2026 at 07:08 UTC.

Consensus RatingBuy
Analyst Count13
Mean TargetUSD 27.58
High TargetUSD 32
Low TargetUSD 20
Buy / Hold / Sell13 / 0 / 0

Earnings (RLAY)

Next Earnings Date2026-11-04
EPS EstimateUSD -0.4
Revenue Estimate$1.58M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.41 vs est -0.39 ▼ miss
2026-03-31USD -0.41 vs est -0.36 ▼ miss
2025-12-31USD -0.31 vs est -0.4 ▲ beat
2025-09-30USD -0.43 vs est -0.42 ▼ miss

Source: Nexqual, October 29, 2026 at 07:08 UTC.

Financials & Fundamentals (RLAY)

Total Revenue$10.35M
Revenue Growth (latest quarter, YoY)-48.30%
Gross Margin+0.00%
Operating Margin-25949.72%
Profit Margin+0.00%
ROE-36.77%
Debt / Equity0.03
Current Ratio18.27
Total Cash$910.93M
Total Debt$30.66M
Free Cash Flow (fiscal year ended Dec 2025, SEC 10-K)-$235.87M (-1536.1% of revenue)

Source: Nexqual, October 29, 2026 at 07:08 UTC.

Financial Health Score (RLAY)

Nexqual rates Relay Therapeutics, Inc.'s overall financial health "Mixed" across five dimensions, as of October 29, 2026 at 07:08 UTC.

GrowthStrong — Revenue +53% YoY (annual)
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $911M cash vs $31M debt, net cash position
Cash FlowWeak — FCF negative: -$236M (FY ended Dec 2025, 10-K), burning cash
EfficiencyCritical — ROE -32%, ROA -29.6% (last 4 quarters, SEC)

Ownership (RLAY)

Insider Ownership+1.58%
Institutional Ownership+110.89%
Shares Outstanding219.14M
Float145.55M
Short % of Float+23.39%

Source: Nexqual, October 29, 2026 at 07:08 UTC.

Leadership (RLAY)

Relay Therapeutics, Inc. is led by Sanjiv K. Patel M.A., M.B.A., M.D., MBBS, CEO, President & Director, per Nexqual as of October 29, 2026 at 07:08 UTC.

CEO, President & DirectorSanjiv K. Patel M.A., M.B.A., M.D., MBBS
Founder & Independent DirectorMark Murcko
Chief Financial OfficerThomas Catinazzo
President of Research & DevelopmentDonald A. Bergstrom
Chief Scientific OfficerJim Watters

Major Backers & Investors (RLAY)

Notable institutional backers of Relay Therapeutics, Inc. include SB Investment Advisers (UK) LTD, FMR, LLC, Casdin Capital, LLC, according to Nexqual as of October 29, 2026 at 07:08 UTC.

Active Investors

InvestorStake
SB Investment Advisers (UK) LTD12.73%
FMR, LLC9.18%
Casdin Capital, LLC7.32%
Perceptive Advisors Llc6.44%
Commodore Capital Lp5.48%
Fidelity4.37%
Price (T.Rowe) Associates Inc3.52%

Index Funds (Passive)

FundStake
BlackRock6.98%
State Street4.62%
Vanguard Group4.09%

Source: Nexqual, October 29, 2026 at 07:08 UTC.

From Relay Therapeutics, Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

SymbolNamePriceChange
RYTMRhythm Pharmaceuticals, Inc.USD 91.97▼ 0.23%
ORKAOruka Therapeutics, Inc.USD 95.97▲ 0.17%
IOVAIovance Biotherapeutics, Inc.USD 14.81▲ 1.58%
IONSIonis Pharmaceuticals, Inc.USD 44.9▲ 2.14%
AXSMAxsome Therapeutics, Inc.USD 143.51▲ 0.92%
PRAXPraxis Precision Medicines, IncUSD 285.48▲ 6.69%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 07:08 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt