Relay Therapeutics, Inc. (RLAY) Stock Price & Analysis
Relay Therapeutics, Inc. (RLAY) closed at USD 19.69 on Wednesday, October 28, 2026, up 4.51% on the day. The US market is currently closed; this is not a live price.
The prior close was USD 18.84; the Oct 28, 2026 session ranged USD 18.6–19.71 on volume of 2,807,593 shares. Market capitalization is $4.31B, with a 52-week range of USD 5.95–21.27 (NGM). Source: Nexqual, retrieved October 29, 2026 at 07:08 UTC.
Also available as compact Markdown for AI agents: nexqual.com/RLAY.md
Key facts (RLAY)
- Last four reported quarters (through Jun 30, 2026): revenue $10.3M, net income -$286M (-2763.6% margin) (SEC filings).
- Insider open-market sales, last ~7 months: 22 Form 4 filings, $128M; 7 not under a Rule 10b5-1 plan ($117M); 4 by opportunistic insiders (0 outside 10b5-1 plans), 17 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Buy (mean 1.77 on a 1–5 scale) (13 analysts), mean target USD 27.58 (range 20–32).
- Total return with dividends: 1Y +169.4% vs S&P 500 +13.6%; 5Y -40.8% vs S&P 500 +79.8%.
- Next earnings: 2026-11-04, EPS estimate USD -0.4, revenue estimate $1.6M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (RLAY)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $3.0M | $1.4M | $25.5M | $10.0M | $15.4M | $10.3M |
| Operating income | -$365M | -$299M | -$373M | -$372M | -$303M | -$310M |
| Net income | -$364M | -$291M | -$342M | -$338M | -$276M | -$286M |
| EPS (diluted) | -$3.82 | -$2.59 | -$2.79 | -$2.36 | -$1.61 | — |
| Free cash flow | -$77.9M | -$239M | -$304M | -$251M | -$236M | — |
| Operating margin | -12040.2% | -21670.9% | -1460.1% | -3722.1% | -1971.6% | -2999.4% |
| Net margin | -12012.9% | -21036.1% | -1338.7% | -3374.7% | -1800.6% | -2763.6% |
| Revenue growth | -96.3% | -54.4% | +1749.8% | -60.8% | +53.4% | — |
| Cash + short-term investments | $280M | $152M | $144M | $124M | $84.0M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (RLAY)
P/S 416.9x · P/B 4.8x · Earnings yield -6.63%
Insider sales (SEC Form 4, open-market, last ~7 months) (RLAY)
15 of 22 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-10-07 | Patel Sanjiv | President and CEO | 48,199 | $872K | 3.4% | Yes (adopted October 30, 2025) | Opportunistic (traded every year 2023–2025, no repeating month) |
| 2026-10-06 | Catinazzo Thomas | Chief Financial Officer | 17,717 | $329K | 14.4% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
| 2026-09-08 | Bergstrom Donald A | President, R&D | 8,530 | $162K | 2.1% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-09-08 | Catinazzo Thomas | Chief Financial Officer | 17,717 | $336K | 12.6% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-09-08 | Patel Sanjiv | President and CEO | 48,199 | $913K | 3.3% | Yes (adopted October 30, 2025) | Opportunistic (traded every year 2023–2025, no repeating month) |
| 2026-08-26 | Rahmer Peter | See remarks | 4,508 | $90K | 2% | Yes (adopted October 31, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-08-25 | Svf Pauling (cayman) Ltd | 6,000,000 | $116M | 21.5% | No | Too little history (no open-market trades in 2023–2025) | |
| 2026-08-17 | Patel Sanjiv | President and CEO | 48,199 | $980K | 3.2% | Yes (adopted October 30, 2025) | Opportunistic (traded every year 2023–2025, no repeating month) |
| 2026-08-14 | Catinazzo Thomas | Chief Financial Officer | 17,717 | $350K | 11.2% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-07-28 | Catinazzo Thomas | Chief Financial Officer | 1,459 | $27K | 0.9% | No | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
| 2026-07-28 | Rahmer Peter | See remarks | 748 | $14K | 0.3% | No | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
| 2026-07-28 | Bergstrom Donald A | President, R&D | 2,237 | $42K | 0.5% | No | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
| 2026-07-07 | Patel Sanjiv | President and CEO | 48,199 | $944K | 3.1% | Yes (adopted October 30, 2025) | Opportunistic (traded every year 2023–2025, no repeating month) |
| 2026-07-06 | Bergstrom Donald A | President, R&D | 8,660 | $162K | 2.1% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
| 2026-07-06 | Catinazzo Thomas | Chief Financial Officer | 17,717 | $331K | 10% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
| 2026-06-30 | Rahmer Peter | See remarks | 50,000 | $955K | 17.9% | Yes (adopted October 31, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-06-22 | Catinazzo Thomas | Chief Financial Officer | 187,163 | $3.2M | 51.3% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-06-22 | Bergstrom Donald A | President, R&D | 93,456 | $1.6M | 18.3% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-05-14 | Catinazzo Thomas | Chief Financial Officer | 17,717 | $228K | 8.3% | Yes (adopted October 30, 2025) | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025; this trade is outside those months) |
| 2026-04-28 | Catinazzo Thomas | Chief Financial Officer | 972 | $14K | 0.5% | No | Routine (sold in Jan & Mar & Apr & Jul & Oct each year 2023–2025) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (RLAY)
Consensus Buy (mean 1.77 on a 1–5 scale), 13 analysts; mean target USD 27.58 (low 20, high 32).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-08-20 | HC Wainwright & Co. | Target raised | Buy | $28 → $29 |
| 2026-08-14 | JP Morgan | Target raised | Overweight | $28 → $31 |
| 2026-08-10 | Citizens | Target raised | Market Outperform | $21 → $26 |
| 2026-08-07 | Barclays | Target raised | Overweight | $27 → $30 |
| 2026-07-21 | Goldman Sachs | Target raised | Buy | $22 → $31 |
| 2026-07-16 | Canaccord Genuity | Initiated | Buy | $29 |
| 2026-07-08 | JP Morgan | Initiated | Overweight | $28 |
Total return (dividends reinvested) (RLAY)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +169.4% | -40.8% |
| S&P 500 (SPY) | +13.6% | +79.8% |
| Per year | +170.3% | -9.9% |
| Volatility (annualized) | 63.0% | 71.5% |
| Max drawdown | -28.1% (Apr 2026→May 2026) | -94.4% (Nov 2021→Mar 2025) |
RLAY earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| — | Quarter ended Jun 30, 2026 | −$0.41 | −$0.39 | Miss −5.1% | — |
| — | Quarter ended Mar 31, 2026 | −$0.41 | −$0.36 | Miss −13.9% | — |
| — | Quarter ended Dec 31, 2025 | −$0.31 | −$0.40 | Beat +22.5% | — |
| — | Quarter ended Sep 30, 2025 | −$0.43 | −$0.42 | Miss −2.4% | — |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
RLAY recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Aug 14, 2026 | Schedule 13G/A | Commodore Capital LP, Commodore Capital Master LP: 5.5% of shares, passive 5%+ holder (amended) |
| Aug 10, 2026 | Schedule 13G/A | Perceptive Advisors LLC, Joseph Edelman: 6.4% of shares, passive 5%+ holder (amended) |
| Aug 7, 2026 | Schedule 13G/A | FMR LLC, Abigail P. Johnson: 10.0% of shares, passive 5%+ holder (amended) |
| Aug 6, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 6, 2026 | 8-K | Entered a material agreement; Quarterly results “Relay Therapeutics, Inc. (the "Company") previously entered into a common stock sales agreement (the "Original Sales Agreement"), dated August 6, 2024, with TD Securities (USA) LLC ("TD Cowen" or the "Sales Agent"), relating to shares of the Company's common stock, par value $0.001 per share (the "Common Stock"), having an aggregate offering price of up to $250,000,000, through TD Cowen. Pursuant to the Original Sales Agreement, the sale and issuance of the shares under the Original Sales Agreement were made…” |
| Aug 6, 2026 | Schedule 13G | FMR LLC, Abigail P. Johnson: 9.4% of shares, passive 5%+ holder |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
RLAY suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Customer | Company and Genentech | “On December 11, 2020, we entered into a Collaboration and License Agreement with Genentech, Inc. and F.” |
| Partner | Elevar Therapeutics | “Additionally, in December 2024, we entered into an exclusive global licensing agreement, or the Elevar Agreement, with Elevar Therapeutics, Inc., or Elevar, pursuant to which Elevar was granted global development and commercialization” |
| Partner | Pfizer (PFE) | “For example, in June 2024, we entered into a global clinical trial collaboration with Pfizer for the development of zovegalisib in combination with fulvestrant and atirmociclib, Pfizer's investigative selective-CDK4 inhibitor, in patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.” |
| Partner | ZebiAI Therapeutics | “Change in fair value of our contingent consideration liability under the Merger Agreement with ZebiAI was $0 for the year ended December 31, 2025 compared to a decrease of $13.2 million for the year ended December 31, 2024.” |
| Partner | Cowen and Company | “In August 2021, we entered into the 2021 Sales Agreement with Cowen, pursuant to which we could offer and sell shares of our common stock having aggregate gross proceeds of up to $300.0 million from time to time in "at-the-market" offerings through Cowen, as our sales agent.” |
Quoted from the company's 10-K filed Feb 26, 2026.
RLAY analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-0.40 | $-0.39 | −$0.01 | $1.6M | 11 |
| Next quarter (ends Dec 2026) | $-0.38 | $-0.36 | −$0.02 | $7.8M | 11 |
| Current fiscal year (ends Dec 2026) | $-1.61 | $-1.53 | −$0.09 | $11.2M | 11 |
| Next fiscal year (ends Dec 2027) | $-1.63 | $-1.64 | +$0.01 | $17.9M | 11 |
Key Statistics (as of October 29, 2026 at 07:08 UTC)
| Price | USD 19.69 |
|---|---|
| Change | ▲ 4.51% (up) |
| Previous Close | USD 18.84 |
| Open | USD 18.62 |
| Day Range | USD 18.6 – 19.71 |
| 52-Week Range | USD 5.95 – 21.27 |
| Volume | 2,807,593 shares |
| Market Cap | $4.31B |
| Exchange | NGM |
Technical Analysis (RLAY)
Nexqual's technical model rates RLAY "BUY" based on 5 bullish and 1 bearish signals across 127 daily candles, as of October 29, 2026 at 07:08 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 60.67 (neutral) |
| vs SMA50 | Above (USD 18.57) |
| MACD | 0.07 (positive) |
Analyst Ratings (RLAY)
Wall Street analysts rate RLAY "Buy" based on 13 analysts, with a mean price target of USD 27.58 (range USD 20–32), per Nexqual as of October 29, 2026 at 07:08 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 13 |
| Mean Target | USD 27.58 |
| High Target | USD 32 |
| Low Target | USD 20 |
| Buy / Hold / Sell | 13 / 0 / 0 |
Earnings (RLAY)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD -0.4 |
| Revenue Estimate | $1.58M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -0.41 vs est -0.39 ▼ miss |
| 2026-03-31 | USD -0.41 vs est -0.36 ▼ miss |
| 2025-12-31 | USD -0.31 vs est -0.4 ▲ beat |
| 2025-09-30 | USD -0.43 vs est -0.42 ▼ miss |
Source: Nexqual, October 29, 2026 at 07:08 UTC.
Financials & Fundamentals (RLAY)
| Total Revenue | $10.35M |
|---|---|
| Revenue Growth (latest quarter, YoY) | -48.30% |
| Gross Margin | +0.00% |
| Operating Margin | -25949.72% |
| Profit Margin | +0.00% |
| ROE | -36.77% |
| Debt / Equity | 0.03 |
| Current Ratio | 18.27 |
| Total Cash | $910.93M |
| Total Debt | $30.66M |
| Free Cash Flow (fiscal year ended Dec 2025, SEC 10-K) | -$235.87M (-1536.1% of revenue) |
Source: Nexqual, October 29, 2026 at 07:08 UTC.
Financial Health Score (RLAY)
Nexqual rates Relay Therapeutics, Inc.'s overall financial health "Mixed" across five dimensions, as of October 29, 2026 at 07:08 UTC.
| Growth | Strong — Revenue +53% YoY (annual) |
|---|---|
| Profitability | Critical — Heavily loss-making — early-stage company |
| Balance Sheet | Strong — $911M cash vs $31M debt, net cash position |
| Cash Flow | Weak — FCF negative: -$236M (FY ended Dec 2025, 10-K), burning cash |
| Efficiency | Critical — ROE -32%, ROA -29.6% (last 4 quarters, SEC) |
Ownership (RLAY)
| Insider Ownership | +1.58% |
|---|---|
| Institutional Ownership | +110.89% |
| Shares Outstanding | 219.14M |
| Float | 145.55M |
| Short % of Float | +23.39% |
Source: Nexqual, October 29, 2026 at 07:08 UTC.
Leadership (RLAY)
Relay Therapeutics, Inc. is led by Sanjiv K. Patel M.A., M.B.A., M.D., MBBS, CEO, President & Director, per Nexqual as of October 29, 2026 at 07:08 UTC.
| CEO, President & Director | Sanjiv K. Patel M.A., M.B.A., M.D., MBBS |
|---|---|
| Founder & Independent Director | Mark Murcko |
| Chief Financial Officer | Thomas Catinazzo |
| President of Research & Development | Donald A. Bergstrom |
| Chief Scientific Officer | Jim Watters |
Major Backers & Investors (RLAY)
Notable institutional backers of Relay Therapeutics, Inc. include SB Investment Advisers (UK) LTD, FMR, LLC, Casdin Capital, LLC, according to Nexqual as of October 29, 2026 at 07:08 UTC.
Active Investors
| Investor | Stake |
|---|---|
| SB Investment Advisers (UK) LTD | 12.73% |
| FMR, LLC | 9.18% |
| Casdin Capital, LLC | 7.32% |
| Perceptive Advisors Llc | 6.44% |
| Commodore Capital Lp | 5.48% |
| Fidelity | 4.37% |
| Price (T.Rowe) Associates Inc | 3.52% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 6.98% |
| State Street | 4.62% |
| Vanguard Group | 4.09% |
Source: Nexqual, October 29, 2026 at 07:08 UTC.
From Relay Therapeutics, Inc.'s Latest SEC 10-K Filing (filed 2026-02-26)
Key Strengths & Strategy (as disclosed to the SEC)
- We seek to protect the intellectual property and proprietary technology that we consider important to our business, including by pursuing patent applications that cover our product candidates and methods of using the same, as well as any other relevant inventions and improvements that we believe to be commercially important to the development of our business.
- We also rely on trade secrets, know-how and continuing technological innovation to develop and maintain our proprietary and intellectual property position.
- As with other biotechnology and pharmaceutical companies, our ability to maintain and solidify our proprietary and intellectual property position for our product candidates and technologies will depend on our success in obtaining effective patent claims and enforcing those claims if granted.
- Our approach pivots the understanding of protein targets from the industry-standard, static view, to a novel paradigm based on fundamental insights into protein motion.
Partnerships
- In December 2024, we entered into the Elevar Agreement with Elevar, pursuant to which Elevar was granted global development and commercialization rights for lirafugratinib, a potent, selective and oral small molecule inhibitor of FGFR2, a receptor tyrosine kinase that is frequently altered in certain cancers.
- On August 17, 2016, we entered into a Collaboration and License Agreement with D.
Legal & Regulatory Risks (Item 1A, quoted)
- Risks Related to Commercialization
- We face substantial competition, which may result in others discovering, developing or commercializing products before or more successfully than we do.
- Any product candidates that we successfully develop and commercialize will compete with currently approved therapies and new therapies that may become available in the future from segments of the pharmaceutical, biotechnology and other related markets that pursue precision medicines.
- Our commercial opportunity could be reduced or eliminated if our competitors develop and commercialize products that are safer, more effective, have fewer or less severe side effects, are more convenient or are less expensive than any products that we or our collaborators may develop.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| RYTM | Rhythm Pharmaceuticals, Inc. | USD 91.97 | ▼ 0.23% |
| ORKA | Oruka Therapeutics, Inc. | USD 95.97 | ▲ 0.17% |
| IOVA | Iovance Biotherapeutics, Inc. | USD 14.81 | ▲ 1.58% |
| IONS | Ionis Pharmaceuticals, Inc. | USD 44.9 | ▲ 2.14% |
| AXSM | Axsome Therapeutics, Inc. | USD 143.51 | ▲ 0.92% |
| PRAX | Praxis Precision Medicines, Inc | USD 285.48 | ▲ 6.69% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 07:08 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt