Xencor, Inc. (XNCR) Stock Price & Analysis

Xencor, Inc. (XNCR) closed at USD 29.21 on Thursday, October 29, 2026, down 2.60% on the day. The US market is currently closed (after-hours); this is not a live price.

The prior close was USD 29.99; the Oct 29, 2026 session ranged USD 28.92–30.56 on volume of 930,369 shares. Market capitalization is $2.17B, with a 52-week range of USD 10.38–33.6 (NGM). Source: Nexqual, retrieved October 29, 2026 at 20:49 UTC.

Also available as compact Markdown for AI agents: nexqual.com/XNCR.md

Key facts (XNCR)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (XNCR)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$275M$165M$175M$110M$126M$105M
Operating income$43.8M-$82.5M-$132M-$178M-$178M-$216M
Net income$82.6M-$55.2M-$133M-$233M-$91.9M-$163M
EPS (diluted)$1.37-$0.93-$2.20-$3.58-$1.24—
Free cash flow-$30.2M-$14.0M-$96.4M-$208M-$138M-$208M
Operating margin15.9%-50.1%-75.8%-161.5%-141.4%-205.8%
Net margin30.0%-33.5%-76.2%-210.5%-73.2%-155.6%
Revenue growth+124.2%-40.2%+6.1%-36.7%+13.7%—
Cash + short-term investments$297M$581M$552M$450M$435M—
Total debt—$0K$189M$164M$120M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (XNCR)

P/S 20.7x · EV/Sales 18.1x · P/B 4.3x · FCF yield -9.59% · Earnings yield -7.52% · Net cash $273M · EV $1.90B

Insider sales (SEC Form 4, open-market, last ~7 months) (XNCR)

5 of 6 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-06-18Feigal EllenDirector6,843$89K35.7%Yes (adopted June 26, 2025)Too little history (no open-market trades in 2023)
2026-06-15Gorman Kevin CharlesDirector7,527$93K39.8%Yes (adopted June 27, 2025)Too little history (no open-market trades in 2023)
2026-06-15Gustafson Kurt ADirector5,474$67K27.1%Yes (adopted June 24, 2025)Too little history (no open-market trades in 2023)
2026-06-15Ranieri Richard JDirector5,474$67K28.5%Yes (adopted June 26, 2025)Too little history (no open-market trades in 2023)
2026-06-15Montgomery Alan BruceDirector5,064$62K24.6%Yes (adopted March 4, 2026)Too little history (no open-market trades in 2023)
2026-04-10Cornelissen Bart JanSR. VICE PRESIDENT & CFO3,499$43K4.4%NoToo little history (no open-market trades in 2023 or 2024)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (XNCR)

Consensus Buy (mean 1.93 on a 1–5 scale), 14 analysts; mean target USD 40.25 (low 21, high 70).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-27Truist SecuritiesTarget raisedBuy$29 → $40
2026-10-27RBC CapitalTarget raisedOutperform$20 → $43
2026-10-27Wells FargoTarget raisedOverweight$30 → $44
2026-10-27WedbushTarget raisedOutperform$30 → $45
2026-10-21WedbushReiteratedOutperform$30
2026-09-28Truist SecuritiesTarget raisedBuy$27 → $29
2026-09-21B of A SecuritiesTarget raisedNeutral$20 → $26
2026-09-11BarclaysTarget raisedOverweight$27 → $35
2026-09-03JP MorganTarget raisedNeutral$14 → $21
2026-09-01Raymond JamesTarget raisedStrong Buy$40 → $46
2026-08-06RBC CapitalTarget raisedOutperform$19 → $20
2026-08-06WedbushTarget raisedOutperform$26 → $30

Total return (dividends reinvested) (XNCR)

1Y (from 2025-10-30)5Y (from 2021-10-25)
Total return+106.7%-26.2%
S&P 500 (SPY)+14.4%+79.1%
Per year+107.2%-5.9%
Volatility (annualized)63.3%53.7%
Max drawdown-42.6% (Dec 2025→May 2026)-82.5% (Nov 2021→Aug 2025)

XNCR earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Oct 26, 2026————+19.1%
Aug 5, 2026Quarter ended Jun 30, 2026−$0.29−$0.84Beat +65.5%+0.4%
Jul 29, 2026Quarter ended Jun 30, 2026−$0.29−$0.84Beat +65.5%+7.6%
May 6, 2026Quarter ended Mar 31, 2026−$1.71−$0.75Miss −128.0%-4.2%
Feb 25, 2026Quarter ended Dec 31, 2025−$0.09−$0.58Beat +84.5%+14.7%
Jan 8, 2026Quarter ended Sep 30, 2025−$0.08−$0.70Beat +88.6%-7.1%
Nov 5, 2025Quarter ended Sep 30, 2025−$0.08−$0.70Beat +88.6%+2.2%
Aug 6, 2025————-7.9%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

XNCR recent SEC filings (last 120 days)

FiledFormWhat it says
Oct 27, 2026Schedule 13G/ABlackRock, Inc.: 14.5% of shares, passive 5%+ holder (amended)
Oct 26, 20268-KQuarterly results; Regulation FD disclosure; Other material event
“On October 25, 2026, the Company issued a press release announcing updated results from the Phase 1 study of XmAb819, an ENPP3 x CD3 T-cell engaging bispecific antibody, in patients with advanced clear cell renal cell carcinoma. A copy of the press release is filed as Exhibit 99.2 to this Current Report on Form 8-K and incorporated herein by reference.”
Aug 5, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 5, 20268-KQuarterly results
Jul 31, 2026Schedule 13GVanguard Capital Management: 5.1% of shares, passive 5%+ holder
Jul 29, 20268-KEntered a material agreement; Quarterly results; Regulation FD disclosure
“On July 29, 2026, Xencor, Inc. (the "Company") entered into a settlement agreement and release (the "Settlement Agreement"), with Alexion Pharma International Operations Limited, an Irish limited company ("Alexion") with respect to a commercial dispute related to U.S. royalties on Ultomiris (ravulizumab-cwvz). Pursuant to the Settlement Agreement, the Company will receive an aggregate of $105 million in two equal payments: the first $52.5 million payment is anticipated in August 2026 and the second $52.5 million…”

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

XNCR revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Royalties$41.2M80.5%+121.5%
Milestone$10.0M19.5%-60.0%
Total revenue$51.2M100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

XNCR suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerAMGEN INC (AMGN)“Amgen: Xaluritamig is a STEAP1 x CD3 2+1 XmAb bispecific T-cell engager that our partner Amgen is advancing for the treatment of patients with prostate cancer.”
PartnerZenas BioPharma, Inc. (ZBIO)“Zenas' partner, Bristol Myers Squibb, holds exclusive development and commercialization rights for obexelimab in Japan, South Korea, Taiwan, Hong Kong, Singapore, and Australia.”
PartnerWuXi“Master Services Agreement with WuXi Biologics (Hong Kong) Limited”
PartnerINCYTE CORP (INCY)“Our partnership and license agreements include those we have with J&J, Genentech, Vir, Amgen, Incyte, Alexion and others.”
PartnerAlexion Pharmaceuticals“Our partnership and license agreements include those we have with J&J, Genentech, Vir, Amgen, Incyte, Alexion and others.”
PartnerAlimentiv“In February 2025, we entered into a master services agreement with Alimentiv Inc. for contract research organizations ("CROs") services supporting clinical trial management and development (including site selection, study design, site monitoring, management and training, and patient selection).”
PartnerOncoBay Clinical“In August 2023, we entered into a master services agreement with OncoBay Clinical, Inc., now known as Kapadi, for CROs services supporting clinical trial management and development (including site selection, study design, site monitoring, management and training, and patient selection).”
PartnerVetter Pharma International“In October 2020, we entered into a master services agreement with Vetter Pharma International GmbH for clinical scale-up, analytical method development, formulation development, and manufacturing of drug product for certain bispecific antibody candidates, including vudalimab and XmAb541.”
PartnerICON Clinical Research“In April 2016, as amended in April 2021, we entered into a master clinical services agreement with ICON Clinical Research Limited for clinical trial services, including site selection, study design, monitoring, and trial management.”
PartnerPPD Development“In June 2015, we entered into a master services agreement with PPD Development, L.P. for clinical trial management and development services (including site selection, study design, site monitoring, management and training, and patient selection).”
PartnerKBI Biopharma“In July 2014, we entered into a master services agreement with KBI Biopharma, Inc. for process development, clinical scale-up, analytical method development, formulation development, and related drug substance and drug product services for certain antibody candidates, including XmAb541 and plamotamab.”
PartnerPAREXEL International“We entered into a master services agreement with PAREXEL International, LLC in April 2014, as amended from time to time, most recently in April 2025, for CROs services supporting clinical trial management and development (including site selection, study design, site monitoring, management and training, and patient selection).”

Quoted from the company's 10-K filed Feb 25, 2026.

Companies that name XNCR in their SEC reports

Relationship to XNCRCompanyFilingSentence
partnerInmune Bio, Inc. (INMB)10-K Mar 30, 2026“entered into a license agreement with Xencor, Inc. ("Xencor"), which has discovered and developed a proprietary biological”
partnerZenas BioPharma, Inc. (ZBIO)10-K Mar 16, 2026“In September 2020, we entered into a license agreement (the "2020 Xencor Agreement") with Xencor, to obtain (i) an exclusive, royalty-bearing, sublicensable worldwide license under certain patent rights controlled by Xencor and (ii) a non-exclusive payment bearing license under certain know-how controlled by Xencor to research, develop, manufacture, market and sell three antibody product candidates (the "2020 Lice…”
partnerINCYTE CORP (INCY)10-K Feb 10, 2026“Under the purchase agreement, we also became the successor to MorphoSys under its collaboration and license agreement with Xencor, Inc. ("Xencor"), pursuant to which Xencor granted MorphoSys an exclusive, worldwide license, including the right to sublicense under certain conditions, for tafasitamab.”

XNCR company outlook (results filed Oct 26, 2026)

Quoted word-for-word from the SEC 8-K results press release.

XNCR analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.34$-0.83+$0.49$63.0M12
Next quarter (ends Dec 2026)$-0.79$-0.74−$0.05$30.1M12
Current fiscal year (ends Dec 2026)$-3.07$-4.03+$0.96$148.8M12
Next fiscal year (ends Dec 2027)$-3.54$-3.55+$0.01$121.0M12

XNCR options: expected move

Options price a move of about ±17.8% (±$5.28) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±7.9% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 20262287.8%±17.8%
Dec 18, 20265079.9%±24.2%
Feb 19, 202711378.8%±35.1%
May 21, 202720473.9%±42.5%

30-day implied volatility 87.3% vs 64.5% realized over the last 30 trading days. Put/call ratio (volume) 0.32. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 29, 2026 at 20:49 UTC)

PriceUSD 29.21
Change▼ 2.60% (down)
Previous CloseUSD 29.99
OpenUSD 30.08
Day RangeUSD 28.92 – 30.56
52-Week RangeUSD 10.38 – 33.6
Volume930,369 shares
Market Cap$2.17B
ExchangeNGM

Technical Analysis (XNCR)

Nexqual's technical model rates XNCR "STRONG BUY" based on 5 bullish and 0 bearish signals across 127 daily candles, as of October 29, 2026 at 20:49 UTC.

Overall SignalSTRONG BUY
RSI (14)66.65 (neutral)
vs SMA50Above (USD 25.68)
MACD1.15 (positive)

Analyst Ratings (XNCR)

Wall Street analysts rate XNCR "Buy" based on 14 analysts, with a mean price target of USD 40.25 (range USD 21–70), per Nexqual as of October 29, 2026 at 20:49 UTC.

Consensus RatingBuy
Analyst Count14
Mean TargetUSD 40.25
High TargetUSD 70
Low TargetUSD 21
Buy / Hold / Sell12 / 2 / 0

Earnings (XNCR)

Next Earnings Date2026-11-04
EPS EstimateUSD -0.34
Revenue Estimate$62.99M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.29 vs est -0.84 ▲ beat
2026-03-31USD -1.71 vs est -0.75 ▼ miss
2025-12-31USD -0.09 vs est -0.58 ▲ beat
2025-09-30USD -0.08 vs est -0.7 ▲ beat

Source: Nexqual, October 29, 2026 at 20:49 UTC.

Financials & Fundamentals (XNCR)

Total Revenue$104.97M
Revenue Growth (latest quarter, YoY)+17.50%
Gross Margin-143.65%
Operating Margin-72.37%
Profit Margin-155.59%
ROE-29.07%
Debt / Equity0.34
Current Ratio6.39
Total Cash$456.45M
Total Debt$170.11M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$208.28M (-198.4% of revenue)

Source: Nexqual, October 29, 2026 at 20:49 UTC.

Financial Health Score (XNCR)

Nexqual rates Xencor, Inc.'s overall financial health "Weak" across five dimensions, as of October 29, 2026 at 20:49 UTC.

GrowthSolid — Revenue +14% YoY (annual)
ProfitabilityCritical — Heavily loss-making — early-stage company
Balance SheetStrong — $378M cash and investments vs $105M debt (Jun 2026, SEC), net cash
Cash FlowWeak — FCF negative: -$208M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE -32%, ROA -22.5% (last 4 quarters, SEC)

Ownership (XNCR)

Insider Ownership+1.22%
Institutional Ownership+114.68%
Shares Outstanding74.35M
Float54.25M
Short % of Float+23.40%

Source: Nexqual, October 29, 2026 at 20:49 UTC.

Leadership (XNCR)

Xencor, Inc. is led by Bassil I. Dahiyat, Co-Founder, CEO, President & Director, per Nexqual as of October 29, 2026 at 20:49 UTC.

Co-Founder, CEO, President & DirectorBassil I. Dahiyat
Senior VP & CFOBart Jan Cornelissen
Executive VP of Research & Chief Scientific OfficerJohn R. Desjarlais
Associate Director and Head of Corporate Communications & Investor RelationsCharles Liles
Senior VIce President of Human ResourcesJennifer Sandoz

Major Backers & Investors (XNCR)

Notable institutional backers of Xencor, Inc. include Primecap Management Company, PRIMECAP Odyssey Funds-PRIMECAP Odyssey Aggressive Growth Fund, BVF Inc., according to Nexqual as of October 29, 2026 at 20:49 UTC.

Active Investors

InvestorStake
Primecap Management Company13.69%
PRIMECAP Odyssey Funds-PRIMECAP Odyssey Aggressive Growth Fund12.69%
BVF Inc.9.59%
RTW Investments LP9.12%
RA Capital Management, L.P.7.09%
TCG Crossover Management, LLC3.3%
Price (T.Rowe) Associates Inc3.17%

Index Funds (Passive)

FundStake
BlackRock18.36%
Vanguard Group7.39%
State Street6.66%

Source: Nexqual, October 29, 2026 at 20:49 UTC.

From Xencor, Inc.'s Latest SEC 10-K Filing (filed 2026-02-25)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

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Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 29, 2026 at 20:49 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt