Caris Life Sciences, Inc. (CAI) Stock Price & Analysis

Caris Life Sciences, Inc. (CAI) closed at USD 31.76 on Thursday, October 15, 2026, up 4.97% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 30.26; the Oct 15, 2026 session ranged USD 28.8–32.15 on volume of 3,457,931 shares. Market capitalization is $8.98B, with a 52-week range of USD 14.19–33.65 (NMS). Source: Nexqual, retrieved October 16, 2026 at 05:21 UTC.

Also available as compact Markdown for AI agents: nexqual.com/CAI.md

Key facts (CAI)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (CAI)

USDFY2025FY2025FY2025TTM
Revenue$306M$412M$812M$990M
Operating income-$320M-$257M$45.1M$153M
Net income-$341M-$282M-$68.1M$105M
EPS (diluted)-$13.24-$10.66-$3.22—
Free cash flow-$298M-$254M$66.9M$124M
Operating margin-104.4%-62.4%5.6%15.5%
Net margin-111.5%-68.4%-8.4%10.6%
Revenue growth—+34.7%+97.0%—
Cash + short-term investments—$66.2M$799M—
Total debt—$380M$379M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (CAI)

P/E 85.4x · P/S 9.1x · P/FCF 72.4x · P/B 15.2x · FCF yield 1.38% · Earnings yield 1.17% · Buyback yield (TTM) 0.24%

Analysts (CAI)

Consensus Buy (mean 2.21 on a 1–5 scale), 14 analysts; mean target USD 31.62 (low 22, high 38).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-10-14JP MorganTarget raisedOverweight$25 → $35
2026-10-13TD CowenTarget raisedBuy$30 → $36
2026-09-09UBSInitiatedNeutral$28
2026-08-06Evercore ISI GroupTarget raisedOutperform$25 → $26
2026-08-06BTIGTarget raisedBuy$32 → $33
2026-08-05JP MorganTarget loweredOverweight$30 → $25
2026-07-06Evercore ISI GroupTarget loweredOutperform$30 → $25
2026-07-02BTIGReiteratedBuy$32

Total return (dividends reinvested) (CAI)

1Y (from 2025-10-16)5Y (from 2025-06-16)
Total return-0.6%+16.6%
S&P 500 (SPY)+18.1%+85.1%
Per year-0.6%+12.2%
Volatility (annualized)68.5%65.5%
Max drawdown-54.5% (Oct 2025→May 2026)-63.0% (Aug 2025→May 2026)

Key Statistics (as of October 16, 2026 at 05:21 UTC)

PriceUSD 31.76
Change▲ 4.97% (up)
Previous CloseUSD 30.26
OpenUSD 29.5
Day RangeUSD 28.8 – 32.15
52-Week RangeUSD 14.19 – 33.65
Volume3,457,931 shares
Market Cap$8.98B
ExchangeNMS

Technical Analysis (CAI)

Nexqual's technical model rates CAI "BUY" based on 5 bullish and 1 bearish signals across 127 daily candles, as of October 16, 2026 at 05:21 UTC.

Overall SignalBUY
RSI (14)62.22 (neutral)
vs SMA50Above (USD 26.86)
MACD0.92 (positive)

Analyst Ratings (CAI)

Wall Street analysts rate CAI "Buy" based on 14 analysts, with a mean price target of USD 31.62 (range USD 22–38), per Nexqual as of October 16, 2026 at 05:21 UTC.

Consensus RatingBuy
Analyst Count14
Mean TargetUSD 31.62
High TargetUSD 38
Low TargetUSD 22
Buy / Hold / Sell10 / 4 / 0

Earnings (CAI)

Next Earnings Date2026-11-04
EPS EstimateUSD 0.02
Revenue Estimate$254.67M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD 0 vs est 0.01 ▼ miss
2026-03-31USD 0 vs est -0.02 ▲ beat
2025-12-31USD 0.28 vs est 0.1 ▲ beat
2025-09-30USD 0.08 vs est -0.14 ▲ beat

Source: Nexqual, October 16, 2026 at 05:21 UTC.

Financials & Fundamentals (CAI)

Total Revenue$989.60M
Revenue Growth (latest quarter, YoY)+45.40%
Gross Margin+69.85%
Operating Margin+10.21%
Profit Margin+10.62%
ROE+20.13%
Debt / Equity0.76
Current Ratio5.53
Total Cash$793.12M
Total Debt$452.40M
Free Cash Flow (fiscal year ended Dec 2025, SEC 10-K)$66.89M (8.2% of revenue)

Source: Nexqual, October 16, 2026 at 05:21 UTC.

Financial Health Score (CAI)

Nexqual rates Caris Life Sciences, Inc.'s overall financial health "Strong" across five dimensions, as of October 16, 2026 at 05:21 UTC.

GrowthStrong — Revenue +45% YoY (latest Q)
ProfitabilityStrong — Gross margin 70%, operating 10%
Balance SheetMixed — $793M cash vs $452M debt, net cash position
Cash FlowSolid — FCF $67M (FY ended Dec 2025, 10-K), 8% margin
EfficiencyStrong — ROE 20%, ROA 8.8%

Ownership (CAI)

Insider Ownership+48.79%
Institutional Ownership+56.59%
Shares Outstanding282.68M
Float134.87M
Short % of Float+12.06%

Source: Nexqual, October 16, 2026 at 05:21 UTC.

Leadership (CAI)

Caris Life Sciences, Inc. is led by David Dean Halbert (age 69), Chairman, CEO & Founder, per Nexqual as of October 16, 2026 at 05:21 UTC.

Chairman, CEO & FounderDavid Dean Halbert (age 69)
Executive Vice Chairman & Executive VPBrian J. Brille (age 64)
PresidentDavid Spetzler M.B.A., M.S. (age 48)
Senior VP, CFO & Chief Accounting OfficerLuke Power (age 43)
Senior VP & CTOValeriy Domenyuk

Major Backers & Investors (CAI)

Notable institutional backers of Caris Life Sciences, Inc. include FMR, LLC, J. H. Whitney Equity Partners VI, LLC, JPMorgan, according to Nexqual as of October 16, 2026 at 05:21 UTC.

Active Investors

InvestorStake
FMR, LLC10.94%
J. H. Whitney Equity Partners VI, LLC3.98%
JPMorgan3.5%
Coatue Management3.47%
Braidwell LP 2.92%
T. Rowe Price2.76%
Fidelity2.71%
Sixth Street Partners Management Company, L.P.2.59%

Index Funds (Passive)

FundStake
Vanguard Group4.77%

Source: Nexqual, October 16, 2026 at 05:21 UTC.

Peers & Related Stocks

SymbolNamePriceChange
TGTXTG Therapeutics, Inc.USD 56▲ 3.05%
AXSMAxsome Therapeutics, Inc.USD 161.79▲ 3.5%
PTGXProtagonist Therapeutics, Inc.USD 136.55▼ 1.4%
CYTKCytokinetics, IncorporatedUSD 63.92▲ 3.73%
TWSTTwist Bioscience CorporationUSD 144.49▼ 4.52%
KYMRKymera Therapeutics, Inc.USD 108.14▲ 1.37%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 16, 2026 at 05:21 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt