Cytokinetics, Incorporated (CYTK) Stock Price & Analysis
Cytokinetics, Incorporated (CYTK) closed at USD 62.33 on Thursday, October 22, 2026, down 0.84% on the day. The US market is currently closed (pre-market); this is not a live price.
The prior close was USD 62.33; the Oct 22, 2026 session ranged USD 61.94–64.07 on volume of 2,061,230 shares. Market capitalization is —, with a 52-week range of USD 54.3–88.31 (NMS). Source: Nexqual, retrieved October 23, 2026 at 09:50 UTC.
Also available as compact Markdown for AI agents: nexqual.com/CYTK.md
Key facts (CYTK)
- Last four reported quarters (through Jun 30, 2026): revenue $67.7M, net income -$894M (-1321.1% margin), free cash flow -$581M (SEC filings).
- Total return with dividends: 1Y +8.4% vs S&P 500 +14.9%; 5Y +68.3% vs S&P 500 +80.3%.
- Next earnings: 2026-11-04, EPS estimate USD -1.41, revenue estimate $41.6M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (CYTK)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $70.4M | $94.6M | $7.5M | $18.5M | $88.0M | $67.7M |
| Operating income | -$186M | -$324M | -$496M | -$536M | -$612M | -$708M |
| Net income | -$215M | -$389M | -$526M | -$590M | -$785M | -$894M |
| EPS (diluted) | -$2.80 | -$4.33 | -$5.45 | -$5.26 | -$6.54 | — |
| Free cash flow | -$191M | -$311M | -$416M | -$400M | -$535M | -$581M |
| Operating margin | -264.5% | -342.8% | -6589.7% | -2902.7% | -695.4% | -1046.1% |
| Net margin | -305.7% | -411.2% | -6988.6% | -3191.1% | -891.6% | -1321.1% |
| Revenue growth | +26.2% | +34.3% | -92.0% | +145.3% | +376.6% | — |
| Cash + short-term investments | $624M | $829M | $655M | $1.20B | $1.20B | — |
| Total debt | $47.4M | $650M | $639M | $620M | $288M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (CYTK)
P/S 128.1x · EV/Sales 107.0x · FCF yield -6.70% · Earnings yield -10.32% · Net cash $1.42B · EV $7.24B
Analysts (CYTK)
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-10-19 | HC Wainwright & Co. | Reiterated | Buy | $140 |
| 2026-10-16 | William Blair | Initiated | Outperform | |
| 2026-10-08 | RBC Capital | Target raised | Outperform | $112 → $113 |
| 2026-08-31 | HC Wainwright & Co. | Reiterated | Buy | $140 |
| 2026-08-13 | Barclays | Target raised | Overweight | $95 → $110 |
| 2026-08-13 | JP Morgan | Target raised | Overweight | $97 → $103 |
| 2026-08-10 | Truist Securities | Target raised | Buy | $106 → $112 |
| 2026-08-07 | RBC Capital | Target lowered | Outperform | $117 → $112 |
| 2026-08-07 | Citizens | Target raised | Market Outperform | $105 → $110 |
| 2026-08-07 | Needham | Target raised | Buy | $102 → $112 |
| 2026-07-07 | RBC Capital | Target lowered | Outperform | $119 → $117 |
| 2026-06-29 | UBS | Upgrade | Neutral → Buy | $69 → $115 |
Total return (dividends reinvested) (CYTK)
| 1Y (from 2025-10-23) | 5Y (from 2021-10-18) | |
|---|---|---|
| Total return | +8.4% | +68.3% |
| S&P 500 (SPY) | +14.9% | +80.3% |
| Per year | +8.4% | +10.9% |
| Volatility (annualized) | 42.1% | 59.3% |
| Max drawdown | -30.0% (Jun 2026→Oct 2026) | -67.4% (Jan 2024→May 2025) |
CYTK revenue by product line (quarter ended Jun 30, 2026)
| Line | Revenue | Share of total | YoY |
|---|---|---|---|
| Net Product Revenue | $25.3M | 88.5% | — |
| Collaboration Revenues | $3.3M | 11.5% | +36.2% |
| Total revenue | $28.6M | 100% | — |
As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).
CYTK suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | Bayer | “Under the terms of our license and collaboration agreements, Sanofi is responsible for the development and commercialization of aficamten (to be commercialized as MYQORZO) in China and Bayer is responsible for the development and commercialization of aficamten in Japan.” |
| Partner | Royalty Pharma Development Funding | “Concurrently, we entered into a common stock purchase agreement with RPFT through which RPFT purchased 875,656 shares of the Company's common stock for $10.0 million.” |
| Competitor | Merck (MRK) | “Omecamtiv mecarbil could also compete against other novel drug candidates and therapies in development, such as those being developed by Novartis AG, Merck & Co., Inc., Bayer AG, AstraZeneca PLC, Kardigan, Inc., and Bristol-Myers Squibb Company.” |
| Competitor | Eli Lilly (LLY) | “Therefore, ulacamten could also compete against other novel drug candidates and therapies in development, such as those being developed by Eli Lilly, Novo Nordisk, Mission Therapeutics, Cardurion Pharmaceuticals and potentially others that may still move into the clinic before potential approval of ulacamten.” |
| Competitor | Novo Nordisk (NVO) | “Therefore, ulacamten could also compete against other novel drug candidates and therapies in development, such as those being developed by Eli Lilly, Novo Nordisk, Mission Therapeutics, Cardurion Pharmaceuticals and potentially others that may still move into the clinic before potential approval of ulacamten.” |
Quoted from the company's 10-K filed Feb 26, 2026.
Companies that name CYTK in their SEC reports
| Relationship to CYTK | Company | Filing | Sentence |
|---|---|---|---|
| partner | Royalty Pharma plc (RPRX) | 10-K Feb 11, 2026 | “In May 2024, we expanded our funding collaboration with Cytokinetics, Incorporated ("Cytokinetics").” |
CYTK customer concentration
In the period ended Jun 30, 2026, 3 direct customers each accounted for at least 10% (36%, 34%, 23%) of revenue, per the company's 10-Q filed Aug 6, 2026. The company does not name them.
CYTK company outlook (results filed Aug 6, 2026)
- “The financial guidance does not include the effect of GAAP adjustments as may be caused by events that occur subsequent to publication of this guidance including, but not limited to, Business Development activities.”
Quoted word-for-word from the SEC 8-K results press release.
CYTK analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-1.41 | $-1.55 | -8.8% | $41.6M | 17 |
| Next quarter (ends Dec 2026) | $-1.39 | $-1.50 | -7.5% | $61.2M | 17 |
| Current fiscal year (ends Dec 2026) | $-5.87 | $-6.32 | -7.1% | $156.3M | 17 |
| Next fiscal year (ends Dec 2027) | $-4.46 | $-4.68 | -4.9% | $428.6M | 17 |
CYTK options: expected move
Options price a move of about ±12.2% (±$7.63) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±6.1% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 28 | 54.1% | ±12.2% |
| Dec 18, 2026 | 56 | 46.8% | ±14.8% |
| Jan 15, 2027 | 84 | 52.9% | ±20.5% |
| Feb 19, 2027 | 119 | 55.0% | ±25.3% |
| May 21, 2027 | 210 | 61.9% | ±37.4% |
30-day implied volatility 53.7% vs 29% realized over the last 30 trading days. Put/call ratio (volume) 0.19. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 23, 2026 at 09:50 UTC)
| Price | USD 62.33 |
|---|---|
| Change | ▼ 0.84% (down) |
| Previous Close | USD 62.33 |
| Open | USD 62.33 |
| Day Range | USD 61.94 – 64.07 |
| 52-Week Range | USD 54.3 – 88.31 |
| Volume | 2,061,230 shares |
| Market Cap | — |
| Exchange | NMS |
Technical Analysis (CYTK)
Nexqual's technical model rates CYTK "STRONG SELL" based on 0 bullish and 5 bearish signals across 127 daily candles, as of October 23, 2026 at 09:50 UTC.
| Overall Signal | STRONG SELL |
|---|---|
| RSI (14) | 38.51 (neutral) |
| vs SMA50 | Below (USD 69.17) |
| MACD | -1.83 (negative) |
Earnings (CYTK)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD -1.41 |
| Revenue Estimate | $41.60M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -1.5 vs est -1.6 ▲ beat |
| 2026-03-31 | USD -1.67 vs est -1.65 ▼ miss |
| 2025-12-31 | USD -1.5 vs est -1.37 ▼ miss |
| 2025-09-30 | USD -1.54 vs est -1.57 ▲ beat |
Source: Nexqual, October 23, 2026 at 09:50 UTC.
Financials & Fundamentals (CYTK)
| Total Revenue | $67.67M |
|---|---|
| Revenue Growth (latest quarter, YoY) | -57.10% |
| Gross Margin | +0.00% |
| Operating Margin | -625.95% |
| Profit Margin | +0.00% |
| Current Ratio | 6.66 |
| Total Cash | $1.17B |
| Total Debt | $1.42B |
Source: Nexqual, October 23, 2026 at 09:50 UTC.
Ownership (CYTK)
| Insider Ownership | +0.57% |
|---|---|
| Institutional Ownership | +125.95% |
| Shares Outstanding | 139.02M |
| Float | 138.49M |
| Short % of Float | +21.23% |
Source: Nexqual, October 23, 2026 at 09:50 UTC.
From Cytokinetics, Incorporated's Latest SEC 10-K Filing (filed 2026-02-26)
Key Strengths & Strategy (as disclosed to the SEC)
- Our market research supports our belief that MYQORZO will be highly competitive amongst cardiac myosin inhibitors, potentially eventually achieving a greater than 50% market share in the United States but also growing the cardiac myosin inhibitor category overall.
- Finally, in January 2026 we submitted a supplemental NDA for MYQORZO to the FDA requesting to include the results of MAPLE-HCM, a Phase 3 randomized, double blind, active-comparator clinical trial of aficamten as monotherapy compared to metoprolol as a monotherapy in patients with obstructive HCM, in the label.
- We submitted a supplemental NDA to the FDA in January 2026 with the intent to include the results of MAPLE-HCM (a Phase 3 randomized, double blind, active-comparator clinical trial of aficamten as monotherapy compared to metoprolol as a monotherapy in patients with obstructive HCM) in the label.
- The FDA granted aficamten orphan drug designation for the treatment of symptomatic HCM in 2021.
Partnerships
- We are party to a collaboration and license agreement with Bayer Consumer Care AG, an affiliate of Bayer AG, for the exclusive development and commercialization of drug products containing aficamten in Japan, subject to certain reserved development rights of Cytokinetics to conduct ACACIA-HCM and CEDAR-HCM in Japan.
- We are party to a revenue interest agreement with RPI ICAV, the RP Aficamten RPA, pursuant to which RPI ICAV purchased rights to certain revenue streams from net sales of MYQORZO and any other future potential pharmaceutical products containing aficamten by us, our affiliates and our licensees.
Legal & Regulatory Risks (Item 1A, quoted)
- We cannot predict the likelihood, nature, or extent of health reform initiatives that may arise from future legislation or administrative action and cannot predict the effect of any of such initiatives on our future financial results or the value of our common stock.
- We may be subject to costly product liability or other liability claims and may not be able to obtain adequate insurance.
- The use of our drugs and drug candidates in clinical trials or by commercial patients may result in adverse events.
- We are subject to laws and regulations relating to privacy, data protection and the collection and processing of personal data. Failure to maintain compliance with these regulations could create additional liabilities for us.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| SYRE | Spyre Therapeutics, Inc. | USD 92.33 | ▼ 0.67% |
| PTGX | Protagonist Therapeutics, Inc. | USD 139.53 | ▲ 1.05% |
| CAI | Caris Life Sciences, Inc. | USD 31.71 | ▼ 1.98% |
| IBRX | ImmunityBio, Inc. | USD 8.31 | ▼ 3.82% |
| ARWR | Arrowhead Pharmaceuticals, Inc. | USD 58.36 | ▼ 0.82% |
| KYMR | Kymera Therapeutics, Inc. | USD 110.85 | ▼ 1.58% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 23, 2026 at 09:50 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt