Pacific Biosciences of California, Inc. (PACB) Stock Price & Analysis
Pacific Biosciences of California, Inc. (PACB) closed at USD 2.83 on Wednesday, October 28, 2026, up 15.51% on the day. The US market is currently closed (after-hours); this is not a live price.
The prior close was USD 2.45; the Oct 28, 2026 session ranged USD 2.44–3.07 on volume of 34,969,050 shares. Market capitalization is $879.65M, with a 52-week range of USD 1.07–3.44 (NMS). Source: Nexqual, retrieved October 28, 2026 at 22:00 UTC.
Also available as compact Markdown for AI agents: nexqual.com/PACB.md
Key facts (PACB)
- Last four reported quarters (through Jun 30, 2026): revenue $159M, net income -$131M (-82.5% margin), free cash flow -$123M (SEC filings).
- Insider open-market sales, last ~7 months: 2 Form 4 filings, $2.1M; 1 not under a Rule 10b5-1 plan ($30K); 0 by opportunistic insiders, 1 by routine insiders (three-year test, Cohen, Malloy & Pomorski 2012).
- Analysts: Hold (mean 2.75 on a 1–5 scale) (8 analysts), mean target USD 2.54 (range 1.25–3.05).
- Total return with dividends: 1Y +40.8% vs S&P 500 +13.6%; 5Y -89.3% vs S&P 500 +79.8%.
- Next earnings: 2026-11-04, EPS estimate USD -0.13, revenue estimate $39.5M.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (PACB)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $131M | $128M | $201M | $154M | $160M | $159M |
| Gross profit | $58.9M | $49.0M | $52.8M | $37.3M | $45.8M | — |
| Operating income | -$210M | -$307M | -$334M | -$474M | -$554M | -$133M |
| Net income | -$181M | -$314M | -$307M | -$310M | -$546M | -$131M |
| EPS (diluted) | -$0.89 | -$1.40 | -$1.21 | -$1.59 | -$1.82 | — |
| Free cash flow | -$117M | -$280M | -$268M | -$212M | -$114M | -$123M |
| Gross margin | 45.1% | 38.2% | 26.3% | 24.2% | 28.6% | — |
| Operating margin | -161.2% | -239.4% | -166.8% | -308.0% | -346.2% | -83.5% |
| Net margin | -138.9% | -244.9% | -153.0% | -201.2% | -341.5% | -82.5% |
| Revenue growth | +65.4% | -1.7% | +56.3% | -23.2% | +3.9% | — |
| Cash + short-term investments | $1.04B | $772M | $631M | $390M | $280M | — |
| Total debt | $898M | $899M | $893M | $647M | $645M | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Jun 30, 2026) (PACB)
P/S 5.5x · EV/Sales 8.1x · FCF yield -14.03% · Earnings yield -14.94% · Net debt $407M · EV $1.29B
Insider sales (SEC Form 4, open-market, last ~7 months) (PACB)
1 of 2 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.
| Trade date | Insider | Role | Shares | Value | % of holdings sold | 10b5-1 plan | Insider type |
|---|---|---|---|---|---|---|---|
| 2026-10-06 | Gibson James R Ii | See Remarks | 661,815 | $2.1M | 37.9% | Yes (adopted May 22, 2026) | Too little history (no open-market trades in 2023–2025) |
| 2026-08-17 | Van Oene Mark | See Remarks | 26,911 | $30K | 1% | No | Routine (sold in Jan & Mar & Aug each year 2023–2025) |
% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (PACB)
Consensus Hold (mean 2.75 on a 1–5 scale), 8 analysts; mean target USD 2.54 (low 1.25, high 3.05).
Total return (dividends reinvested) (PACB)
| 1Y (from 2025-10-29) | 5Y (from 2021-10-25) | |
|---|---|---|
| Total return | +40.8% | -89.3% |
| S&P 500 (SPY) | +13.6% | +79.8% |
| Per year | +41.0% | -36.0% |
| Volatility (annualized) | 93.4% | 97.5% |
| Max drawdown | -58.4% (Jan 2026→Aug 2026) | -96.8% (Nov 2021→May 2025) |
PACB earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Aug 5, 2026 | Quarter ended Jun 30, 2026 | −$0.14 | −$0.13 | Miss −7.7% | -18.8% |
| May 7, 2026 | Quarter ended Mar 31, 2026 | −$0.12 | −$0.13 | Beat +7.7% | -17.5% |
| Feb 12, 2026 | Quarter ended Dec 31, 2025 | −$0.12 | −$0.13 | Beat +7.7% | -7.1% |
| Jan 12, 2026 | Quarter ended Dec 31, 2025 | −$0.12 | −$0.13 | Beat +7.7% | +9.8% |
| Nov 5, 2025 | Quarter ended Sep 30, 2025 | −$0.12 | −$0.14 | Beat +14.3% | -11.0% |
| Aug 7, 2025 | — | — | — | — | -2.2% |
| May 8, 2025 | — | — | — | — | -0.9% |
| Apr 9, 2025 | — | — | — | — | +15.0% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
PACB recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Aug 14, 2026 | Schedule 13G/A | ARK Investment Management LLC, Catherine D. Wood: 9.6% of shares, passive 5%+ holder (amended) |
| Aug 6, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 5, 2026 | 8-K | Quarterly results; Exit or restructuring costs (layoffs, closures); Director or executive officer change, or pay arrangement; Regulation FD disclosure “On July 30, 2026, the Board of Directors (the "Board") of the Company approved a restructuring plan to continue to better align the Company's organizational structure and resources with its strategic initiatives. The restructuring includes operating expense reductions and a reduction in force (the "Reduction in Force"). These restructuring actions are expected to result in a workforce reduction of approximately 40 employees, or approximately 8% of the Company's workforce, as the Company aligns its organizational…” |
| Jul 9, 2026 | 8-K | Director or executive officer change, or pay arrangement “On July 8, 2026, Christopher M. Smith, a member of the board of directors (the "Board") of Pacific Biosciences of California, Inc. (the "Company"), notified the Company of his resignation from the Board, effective immediately. The Company is not aware of any disagreement between Mr. Smith and the Company on any matter relating to the Company's operations, policies or practices that resulted in Mr. Smith's resignation.” |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
PACB revenue by product line (quarter ended Jun 30, 2026)
| Line | Revenue | Share of total | YoY |
|---|---|---|---|
| Product revenue | $33.0M | 84.5% | -0.4% |
| — Consumable revenue (part of Product revenue) | $20.1M | 51.6% | +6.2% |
| — Instrument revenue (part of Product revenue) | $12.8M | 32.9% | -9.3% |
| Service and other revenue | $6.1M | 15.5% | -9.4% |
| Total revenue | $39.0M | 100% | — |
PACB revenue by region (quarter ended Jun 30, 2026)
| Line | Revenue | Share of total | YoY |
|---|---|---|---|
| Americas | $17.6M | 45.2% | -0.4% |
| Europe, Middle East and Africa | $14.4M | 37.0% | +52.4% |
| Asia-Pacific | $7.0M | 17.8% | -44.8% |
| Total revenue | $39.0M | 100% | — |
As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).
PACB suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | SOFTBANK GROUP CORP. (SFTBF) | “On February 9, 2021, we entered into an investment agreement with SB Northstar LP ("SBN"), a subsidiary of SoftBank Group Corp., relating to the issuance and sale to SBN of $900.0 million in aggregate principal amount of our 2028 Notes.” |
Quoted from the company's 10-K filed Feb 25, 2026.
PACB company outlook (results filed Aug 5, 2026)
- “PacBio expects revenue for the full year 2026 to be in the range of $155 million to $165 million.”
Quoted word-for-word from the SEC 8-K results press release.
PACB analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Sep 2026) | $-0.13 | $-0.13 | $0.00 | $39.5M | 7 |
| Next quarter (ends Dec 2026) | $-0.13 | $-0.13 | $0.00 | $43.0M | 7 |
| Current fiscal year (ends Dec 2026) | $-0.52 | $-0.51 | −$0.01 | $158.7M | 7 |
| Next fiscal year (ends Dec 2027) | $-0.42 | $-0.39 | −$0.03 | $184.1M | 7 |
PACB options: expected move
Options price a move of about ±24.7% (±$0.75) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±10.3% on average.
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 23 | 124.5% | ±24.7% |
| Dec 18, 2026 | 51 | 133.0% | ±38.7% |
| Jan 15, 2027 | 79 | 114.5% | ±41.2% |
| Mar 19, 2027 | 142 | 121.1% | ±56.8% |
| Jun 17, 2027 | 232 | 95.7% | ±56.8% |
30-day implied volatility 119.7% vs 133.9% realized over the last 30 trading days. Put/call ratio (volume) 0.02. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of October 28, 2026 at 22:00 UTC)
| Price | USD 2.83 |
|---|---|
| Change | ▲ 15.51% (up) |
| Previous Close | USD 2.45 |
| Open | USD 2.45 |
| Day Range | USD 2.44 – 3.07 |
| 52-Week Range | USD 1.07 – 3.44 |
| Volume | 34,969,050 shares |
| Market Cap | $879.65M |
| Exchange | NMS |
Technical Analysis (PACB)
Nexqual's technical model rates PACB "BUY" based on 5 bullish and 2 bearish signals across 127 daily candles, as of October 28, 2026 at 22:00 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 71.51 (overbought) |
| vs SMA50 | Above (USD 1.77) |
| MACD | 0.16 (positive) |
Analyst Ratings (PACB)
Wall Street analysts rate PACB "Hold" based on 8 analysts, with a mean price target of USD 2.54 (range USD 1.25–3.05), per Nexqual as of October 28, 2026 at 22:00 UTC.
| Consensus Rating | Hold |
|---|---|
| Analyst Count | 8 |
| Mean Target | USD 2.54 |
| High Target | USD 3.05 |
| Low Target | USD 1.25 |
| Buy / Hold / Sell | 4 / 3 / 1 |
Earnings (PACB)
| Next Earnings Date | 2026-11-04 |
|---|---|
| EPS Estimate | USD -0.13 |
| Revenue Estimate | $39.46M |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-06-30 | USD -0.14 vs est -0.13 ▼ miss |
| 2026-03-31 | USD -0.12 vs est -0.13 ▲ beat |
| 2025-12-31 | USD -0.12 vs est -0.13 ▲ beat |
| 2025-09-30 | USD -0.12 vs est -0.14 ▲ beat |
Source: Nexqual, October 28, 2026 at 22:00 UTC.
Financials & Fundamentals (PACB)
| Total Revenue | $159.27M |
|---|---|
| Revenue Growth (latest quarter, YoY) | -1.90% |
| Gross Margin | +29.42% |
| Operating Margin | -114.36% |
| Profit Margin | -82.49% |
| ROE | -929.32% |
| Current Ratio | 4.92 |
| Total Cash | $236.87M |
| Total Debt | $709.13M |
| Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K) | -$123.42M (-77.5% of revenue) |
Source: Nexqual, October 28, 2026 at 22:00 UTC.
Financial Health Score (PACB)
Nexqual rates Pacific Biosciences of California, Inc.'s overall financial health "Weak" across five dimensions, as of October 28, 2026 at 22:00 UTC.
| Growth | Mixed — Revenue +3.9% YoY (annual), slow |
|---|---|
| Profitability | Weak — Gross margin 36%, operating -84% (last 4 quarters to Jun 2026, SEC) |
| Balance Sheet | Mixed — $237M cash and investments vs $644M debt (Jun 2026, SEC) |
| Cash Flow | Weak — FCF negative: -$123M (last 4 quarters to Jun 2026, SEC), burning cash |
| Efficiency | Critical — ROE not meaningful (negative equity); ROA -17.5% (last 4 quarters, SEC) |
Ownership (PACB)
| Insider Ownership | +8.86% |
|---|---|
| Institutional Ownership | +56.94% |
| Shares Outstanding | 310.83M |
| Float | 304.17M |
| Short % of Float | +17.36% |
Source: Nexqual, October 28, 2026 at 22:00 UTC.
Leadership (PACB)
Pacific Biosciences of California, Inc. is led by Mark Van Oene, CEO, President & Director, per Nexqual as of October 28, 2026 at 22:00 UTC.
| CEO, President & Director | Mark Van Oene |
|---|---|
| CFO & Principal Accounting Officer | James R. Gibson |
| Senior Business Advisor & Director | Christian O. Henry |
Major Backers & Investors (PACB)
Notable institutional backers of Pacific Biosciences of California, Inc. include ARK Invest, Softbank Group Corporation, Sumitomo Mitsui Trust Group, Inc., according to Nexqual as of October 28, 2026 at 22:00 UTC.
Active Investors
| Investor | Stake |
|---|---|
| ARK Invest | 9.58% |
| Softbank Group Corporation | 6.58% |
| Sumitomo Mitsui Trust Group, Inc. | 1.93% |
| Amova Asset Management Americas Inc | 1.93% |
| Point72 Asset Management, L.P. | 1.54% |
| Two Sigma Investments, LP | 1.36% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 10.4% |
| Vanguard Group | 4.31% |
| Geode Capital | 2.45% |
| State Street | 1.92% |
Source: Nexqual, October 28, 2026 at 22:00 UTC.
From Pacific Biosciences of California, Inc.'s Latest SEC 10-K Filing (filed 2026-02-25)
Key Strengths & Strategy (as disclosed to the SEC)
- Customers purchase proprietary consumable products to run their PacBio systems, including our SMRT Cells and reagent kits.
- Our HiFi long-read sequencing protocol was built upon our SMRT sequencing systems, including consumables and software, and offers customized end-to-end workflows for different sequencing applications.
- Our proprietary SMRT sequencing technology enables the direct observation of DNA synthesis in real time by monitoring the activity of individual DNA polymerase molecules as they incorporate nucleotides into a growing DNA strand.
- We also innovate across end-to-end workflows to improve usability, as well as develop new applications for the advancement of human health.
Partnerships
- We provide required compliance training for employees, along with targeted, function-specific training where applicable, and ongoing learning through cross-functional collaboration and knowledge sharing.
Legal & Regulatory Risks (Item 1A, quoted)
- Our products are highly complex, have recurring support requirements and could have unknown defects or errors, which may give rise to claims against us or divert application of our resources from other purposes.
- Changes in tax law and differences in interpretation of tax laws and regulations could adversely impact our business and financial condition.
- The measures that we use to protect the security of and enforce our intellectual property and other proprietary rights may not be adequate, which could result in the loss of legal protection for, and thereby diminish the value of, such intellectual property and other rights.
- We have been, are currently, and could in the future be, subject to legal proceedings with third parties who may claim that our products infringe or misappropriate their intellectual property rights.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| ESTA | Establishment Labs Holdings Inc | USD 68.97 | ▲ 3.02% |
| BFLY | Butterfly Network, Inc. | USD 7.81 | ▲ 5.83% |
| INSP | Inspire Medical Systems, Inc. | USD 70.97 | ▼ 0.46% |
| UFPT | UFP Technologies, Inc. | USD 286 | ▼ 3% |
| ALMR | Alamar Biosciences, Inc. | USD 34.3 | ▲ 7.42% |
| TMDX | TransMedics Group, Inc. | USD 66.9 | ▼ 4.06% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 28, 2026 at 22:00 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt