Pacific Biosciences of California, Inc. (PACB) Stock Price & Analysis

Pacific Biosciences of California, Inc. (PACB) closed at USD 2.83 on Wednesday, October 28, 2026, up 15.51% on the day. The US market is currently closed (after-hours); this is not a live price.

The prior close was USD 2.45; the Oct 28, 2026 session ranged USD 2.44–3.07 on volume of 34,969,050 shares. Market capitalization is $879.65M, with a 52-week range of USD 1.07–3.44 (NMS). Source: Nexqual, retrieved October 28, 2026 at 22:00 UTC.

Also available as compact Markdown for AI agents: nexqual.com/PACB.md

Key facts (PACB)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (PACB)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$131M$128M$201M$154M$160M$159M
Gross profit$58.9M$49.0M$52.8M$37.3M$45.8M—
Operating income-$210M-$307M-$334M-$474M-$554M-$133M
Net income-$181M-$314M-$307M-$310M-$546M-$131M
EPS (diluted)-$0.89-$1.40-$1.21-$1.59-$1.82—
Free cash flow-$117M-$280M-$268M-$212M-$114M-$123M
Gross margin45.1%38.2%26.3%24.2%28.6%—
Operating margin-161.2%-239.4%-166.8%-308.0%-346.2%-83.5%
Net margin-138.9%-244.9%-153.0%-201.2%-341.5%-82.5%
Revenue growth+65.4%-1.7%+56.3%-23.2%+3.9%—
Cash + short-term investments$1.04B$772M$631M$390M$280M—
Total debt$898M$899M$893M$647M$645M—

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Jun 30, 2026) (PACB)

P/S 5.5x · EV/Sales 8.1x · FCF yield -14.03% · Earnings yield -14.94% · Net debt $407M · EV $1.29B

Insider sales (SEC Form 4, open-market, last ~7 months) (PACB)

1 of 2 under a Rule 10b5-1 trading plan (scheduled in advance). Unplanned sales were timed by the insider.

Trade dateInsiderRoleSharesValue% of holdings sold10b5-1 planInsider type
2026-10-06Gibson James R IiSee Remarks661,815$2.1M37.9%Yes (adopted May 22, 2026)Too little history (no open-market trades in 2023–2025)
2026-08-17Van Oene MarkSee Remarks26,911$30K1%NoRoutine (sold in Jan & Mar & Aug each year 2023–2025)

% of holdings sold = shares sold ÷ (shares sold + all holdings the insider reported on that Form 4, direct and through trusts).

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (PACB)

Consensus Hold (mean 2.75 on a 1–5 scale), 8 analysts; mean target USD 2.54 (low 1.25, high 3.05).

Total return (dividends reinvested) (PACB)

1Y (from 2025-10-29)5Y (from 2021-10-25)
Total return+40.8%-89.3%
S&P 500 (SPY)+13.6%+79.8%
Per year+41.0%-36.0%
Volatility (annualized)93.4%97.5%
Max drawdown-58.4% (Jan 2026→Aug 2026)-96.8% (Nov 2021→May 2025)

PACB earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Aug 5, 2026Quarter ended Jun 30, 2026−$0.14−$0.13Miss −7.7%-18.8%
May 7, 2026Quarter ended Mar 31, 2026−$0.12−$0.13Beat +7.7%-17.5%
Feb 12, 2026Quarter ended Dec 31, 2025−$0.12−$0.13Beat +7.7%-7.1%
Jan 12, 2026Quarter ended Dec 31, 2025−$0.12−$0.13Beat +7.7%+9.8%
Nov 5, 2025Quarter ended Sep 30, 2025−$0.12−$0.14Beat +14.3%-11.0%
Aug 7, 2025————-2.2%
May 8, 2025————-0.9%
Apr 9, 2025————+15.0%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

PACB recent SEC filings (last 120 days)

FiledFormWhat it says
Aug 14, 2026Schedule 13G/AARK Investment Management LLC, Catherine D. Wood: 9.6% of shares, passive 5%+ holder (amended)
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 5, 20268-KQuarterly results; Exit or restructuring costs (layoffs, closures); Director or executive officer change, or pay arrangement; Regulation FD disclosure
“On July 30, 2026, the Board of Directors (the "Board") of the Company approved a restructuring plan to continue to better align the Company's organizational structure and resources with its strategic initiatives. The restructuring includes operating expense reductions and a reduction in force (the "Reduction in Force"). These restructuring actions are expected to result in a workforce reduction of approximately 40 employees, or approximately 8% of the Company's workforce, as the Company aligns its organizational…”
Jul 9, 20268-KDirector or executive officer change, or pay arrangement
“On July 8, 2026, Christopher M. Smith, a member of the board of directors (the "Board") of Pacific Biosciences of California, Inc. (the "Company"), notified the Company of his resignation from the Board, effective immediately. The Company is not aware of any disagreement between Mr. Smith and the Company on any matter relating to the Company's operations, policies or practices that resulted in Mr. Smith's resignation.”

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

PACB revenue by product line (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Product revenue$33.0M84.5%-0.4%
— Consumable revenue (part of Product revenue)$20.1M51.6%+6.2%
— Instrument revenue (part of Product revenue)$12.8M32.9%-9.3%
Service and other revenue$6.1M15.5%-9.4%
Total revenue$39.0M100%—

PACB revenue by region (quarter ended Jun 30, 2026)

LineRevenueShare of totalYoY
Americas$17.6M45.2%-0.4%
Europe, Middle East and Africa$14.4M37.0%+52.4%
Asia-Pacific$7.0M17.8%-44.8%
Total revenue$39.0M100%—

As tagged by the company in its SEC 10-Q / 10-K filings (XBRL).

PACB suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerSOFTBANK GROUP CORP. (SFTBF)“On February 9, 2021, we entered into an investment agreement with SB Northstar LP ("SBN"), a subsidiary of SoftBank Group Corp., relating to the issuance and sale to SBN of $900.0 million in aggregate principal amount of our 2028 Notes.”

Quoted from the company's 10-K filed Feb 25, 2026.

PACB company outlook (results filed Aug 5, 2026)

Quoted word-for-word from the SEC 8-K results press release.

PACB analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Sep 2026)$-0.13$-0.13$0.00$39.5M7
Next quarter (ends Dec 2026)$-0.13$-0.13$0.00$43.0M7
Current fiscal year (ends Dec 2026)$-0.52$-0.51−$0.01$158.7M7
Next fiscal year (ends Dec 2027)$-0.42$-0.39−$0.03$184.1M7

PACB options: expected move

Options price a move of about ±24.7% (±$0.75) by Nov 20, 2026, which includes earnings on Nov 4, 2026. Over the last 8 reports the stock moved ±10.3% on average.

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202623124.5%±24.7%
Dec 18, 202651133.0%±38.7%
Jan 15, 202779114.5%±41.2%
Mar 19, 2027142121.1%±56.8%
Jun 17, 202723295.7%±56.8%

30-day implied volatility 119.7% vs 133.9% realized over the last 30 trading days. Put/call ratio (volume) 0.02. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of October 28, 2026 at 22:00 UTC)

PriceUSD 2.83
Change▲ 15.51% (up)
Previous CloseUSD 2.45
OpenUSD 2.45
Day RangeUSD 2.44 – 3.07
52-Week RangeUSD 1.07 – 3.44
Volume34,969,050 shares
Market Cap$879.65M
ExchangeNMS

Technical Analysis (PACB)

Nexqual's technical model rates PACB "BUY" based on 5 bullish and 2 bearish signals across 127 daily candles, as of October 28, 2026 at 22:00 UTC.

Overall SignalBUY
RSI (14)71.51 (overbought)
vs SMA50Above (USD 1.77)
MACD0.16 (positive)

Analyst Ratings (PACB)

Wall Street analysts rate PACB "Hold" based on 8 analysts, with a mean price target of USD 2.54 (range USD 1.25–3.05), per Nexqual as of October 28, 2026 at 22:00 UTC.

Consensus RatingHold
Analyst Count8
Mean TargetUSD 2.54
High TargetUSD 3.05
Low TargetUSD 1.25
Buy / Hold / Sell4 / 3 / 1

Earnings (PACB)

Next Earnings Date2026-11-04
EPS EstimateUSD -0.13
Revenue Estimate$39.46M

Recent Earnings History

QuarterActual vs Estimate
2026-06-30USD -0.14 vs est -0.13 ▼ miss
2026-03-31USD -0.12 vs est -0.13 ▲ beat
2025-12-31USD -0.12 vs est -0.13 ▲ beat
2025-09-30USD -0.12 vs est -0.14 ▲ beat

Source: Nexqual, October 28, 2026 at 22:00 UTC.

Financials & Fundamentals (PACB)

Total Revenue$159.27M
Revenue Growth (latest quarter, YoY)-1.90%
Gross Margin+29.42%
Operating Margin-114.36%
Profit Margin-82.49%
ROE-929.32%
Current Ratio4.92
Total Cash$236.87M
Total Debt$709.13M
Free Cash Flow (last four quarters to Jun 2026, SEC 10-Q / 10-K)-$123.42M (-77.5% of revenue)

Source: Nexqual, October 28, 2026 at 22:00 UTC.

Financial Health Score (PACB)

Nexqual rates Pacific Biosciences of California, Inc.'s overall financial health "Weak" across five dimensions, as of October 28, 2026 at 22:00 UTC.

GrowthMixed — Revenue +3.9% YoY (annual), slow
ProfitabilityWeak — Gross margin 36%, operating -84% (last 4 quarters to Jun 2026, SEC)
Balance SheetMixed — $237M cash and investments vs $644M debt (Jun 2026, SEC)
Cash FlowWeak — FCF negative: -$123M (last 4 quarters to Jun 2026, SEC), burning cash
EfficiencyCritical — ROE not meaningful (negative equity); ROA -17.5% (last 4 quarters, SEC)

Ownership (PACB)

Insider Ownership+8.86%
Institutional Ownership+56.94%
Shares Outstanding310.83M
Float304.17M
Short % of Float+17.36%

Source: Nexqual, October 28, 2026 at 22:00 UTC.

Leadership (PACB)

Pacific Biosciences of California, Inc. is led by Mark Van Oene, CEO, President & Director, per Nexqual as of October 28, 2026 at 22:00 UTC.

CEO, President & DirectorMark Van Oene
CFO & Principal Accounting OfficerJames R. Gibson
Senior Business Advisor & DirectorChristian O. Henry

Major Backers & Investors (PACB)

Notable institutional backers of Pacific Biosciences of California, Inc. include ARK Invest, Softbank Group Corporation, Sumitomo Mitsui Trust Group, Inc., according to Nexqual as of October 28, 2026 at 22:00 UTC.

Active Investors

InvestorStake
ARK Invest9.58%
Softbank Group Corporation6.58%
Sumitomo Mitsui Trust Group, Inc.1.93%
Amova Asset Management Americas Inc1.93%
Point72 Asset Management, L.P.1.54%
Two Sigma Investments, LP1.36%

Index Funds (Passive)

FundStake
BlackRock10.4%
Vanguard Group4.31%
Geode Capital2.45%
State Street1.92%

Source: Nexqual, October 28, 2026 at 22:00 UTC.

From Pacific Biosciences of California, Inc.'s Latest SEC 10-K Filing (filed 2026-02-25)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

SymbolNamePriceChange
ESTAEstablishment Labs Holdings IncUSD 68.97▲ 3.02%
BFLYButterfly Network, Inc.USD 7.81▲ 5.83%
INSPInspire Medical Systems, Inc.USD 70.97▼ 0.46%
UFPTUFP Technologies, Inc.USD 286▼ 3%
ALMRAlamar Biosciences, Inc.USD 34.3▲ 7.42%
TMDXTransMedics Group, Inc.USD 66.9▼ 4.06%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: October 28, 2026 at 22:00 UTC. This page is informational and not investment advice.

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