Vaxcyte, Inc. (PCVX) Stock Price & Analysis
Vaxcyte, Inc. (PCVX) rose 1.19% to USD 46.88 as of June 10, 2026 at 00:52 UTC, according to Nexqual real-time market data.
PCVX last closed at USD 46.33; the session ranged USD 46.1–47.6 on volume of 1,008,607 shares. Market capitalization is $6.77B, with a 52-week range of USD 29.08–65 (NMS). Source: Nexqual, June 10, 2026 at 00:52 UTC.
Key Statistics (as of June 10, 2026 at 00:52 UTC)
| Price | USD 46.88 |
|---|---|
| Change | ▲ 1.19% (up) |
| Previous Close | USD 46.33 |
| Open | USD 46.93 |
| Day Range | USD 46.1 – 47.6 |
| 52-Week Range | USD 29.08 – 65 |
| Volume | 1,008,607 shares |
| Market Cap | $6.77B |
| Exchange | NMS |
Technical Analysis (PCVX)
Nexqual's technical model rates PCVX "STRONG SELL" based on 0 bullish and 5 bearish signals across 124 daily candles, as of June 10, 2026 at 00:52 UTC.
| Overall Signal | STRONG SELL |
|---|---|
| RSI (14) | 34.81 (neutral) |
| vs SMA50 | Below (USD 55.11) |
| MACD | -2.2 (negative) |
Analyst Ratings (PCVX)
Wall Street analysts rate PCVX "Strong Buy" based on 9 analysts, with a mean price target of USD 109 (range USD 67–163), per Nexqual as of June 10, 2026 at 00:52 UTC.
| Consensus Rating | Strong Buy |
|---|---|
| Analyst Count | 9 |
| Mean Target | USD 109 |
| High Target | USD 163 |
| Low Target | USD 67 |
| Buy / Hold / Sell | 10 / 1 / 0 |
Earnings (PCVX)
| Next Earnings Date | 2026-08-05 |
|---|---|
| EPS Estimate | USD -2.1 |
| Revenue Estimate | $0 |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-03-31 | USD -2.3 vs est -1.77 ▼ miss |
| 2025-12-31 | USD -1.8 vs est -1.5 ▼ miss |
| 2025-09-30 | USD -1.56 vs est -1.24 ▼ miss |
| 2025-06-30 | USD -1.22 vs est -1.16 ▼ miss |
Source: Nexqual, June 10, 2026 at 00:52 UTC.
Financials & Fundamentals (PCVX)
| Gross Margin | +0.00% |
|---|---|
| Operating Margin | +0.00% |
| Profit Margin | +0.00% |
| ROE | -30.55% |
| Debt / Equity | 3.88 |
| Current Ratio | 7.49 |
| Total Cash | $1.74B |
| Total Debt | $116.30M |
| Free Cash Flow | $-439.79M |
Source: Nexqual, June 10, 2026 at 00:52 UTC.
Financial Health Score (PCVX)
Nexqual rates Vaxcyte, Inc.'s overall financial health "Mixed" across five dimensions, as of June 10, 2026 at 00:52 UTC.
| Growth | Mixed — No data |
|---|---|
| Profitability | Weak — Pre-revenue or very early stage |
| Balance Sheet | Strong — $1.74B cash vs $116M debt, net cash position |
| Cash Flow | Weak — Operating cash flow -$770M |
| Efficiency | Critical — ROE -31%, ROA -20.2% |
Ownership (PCVX)
| Insider Ownership | +0.53% |
|---|---|
| Institutional Ownership | +114.57% |
| Shares Outstanding | 144.40M |
| Float | 131.96M |
| Short % of Float | +9.60% |
Source: Nexqual, June 10, 2026 at 00:52 UTC.
Leadership (PCVX)
Vaxcyte, Inc. is led by Grant E. Pickering (age 57), Co-Founder, CEO & Director, per Nexqual as of June 10, 2026 at 00:52 UTC.
| Co-Founder, CEO & Director | Grant E. Pickering (age 57) |
|---|---|
| President & CFO | Andrew L. Guggenhime (age 57) |
| Executive VP & COO | James T. Wassil M.B.A., M.S. (age 56) |
| Executive Director of Investor Relations | Jeff Macdonald |
| Senior Vice President of Corporate Affairs | Janet Graesser |
Major Backers & Investors (PCVX)
Notable institutional backers of Vaxcyte, Inc. include Janus Henderson Group PLC, FMR, LLC, T. Rowe Price, according to Nexqual as of June 10, 2026 at 00:52 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Janus Henderson Group PLC | 11.48% |
| FMR, LLC | 11.42% |
| T. Rowe Price | 10.16% |
| RA Capital Management, L.P. | 7.95% |
| Wellington Management | 3.89% |
| Paradigm Biocapital Advisors LP | 3.32% |
| JANUS INVESTMENT FUND-Janus Henderson Enterprise Fund | 3.12% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| Vanguard Group | 17.73% |
| BlackRock | 9.62% |
| State Street | 4.22% |
Source: Nexqual, June 10, 2026 at 00:52 UTC.
From Vaxcyte, Inc.'s Latest SEC 10-K Filing (filed 2026-02-24)
Key Strengths & Strategy (as disclosed to the SEC)
- Our Platform Our modern synthetic techniques, including advanced chemistry and the XpressCF™ cell-free protein synthesis platform, offer several advantages over conventional cell-based protein expression methods, which we believe enable us to generate superior, novel, broader-spectrum and/or more immunogenic vaccines.
- The vaccines to prevent RSV from Pfizer and GSK that were approved by the FDA in May 2023, and from Moderna that was approved by the FDA in May 2024, generated approximately $1.8 billion in global sales in 2025.
- In that study, the OPA responses directed against the polysaccharides of interest for all thirteen of the common strains were lower for PCV20 (Figure 6). 12 Table of Contents 1 IgG Geometric Mean Concentrations post-dose 4 – Prevnar 20 Biologics License Application ("BLA") Clinical Review Memorandum by FDA (STN: 125731/189).
- In contrast, the precision and flexibility of cell-free protein expression, together with our ability to insert nnAAs, allow us to construct our proprietary enhanced protein carrier ("eCRM") with pre-determined conjugation sites.
Partnerships
- In addition, in September 2025, we announced a new agreement with Patheon Manufacturing Services, LLC, part of Thermo Fisher Scientific (collectively, "Thermo Fisher") to provide custom commercial fill-finish capacity for our broad-spectrum PCVs at Thermo Fisher's Greenville, North Carolina facility.
- In October 2023, to complement this plan, we entered into a new commercial manufacturing agreement with Lonza to support the potential global commercialization of our PCV candidates in both the adult and pediatric populations.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| NUVL | Nuvalent, Inc. | USD 123.25 | ▲ 35.51% |
| KYMR | Kymera Therapeutics, Inc. | USD 76.91 | ▲ 3.75% |
| LEGN | Legend Biotech Corporation | USD 33.49 | ▲ 2.67% |
| CRNX | Crinetics Pharmaceuticals, Inc. | USD 34.97 | ▲ 6.23% |
| KROS | Keros Therapeutics, Inc. | USD 10.07 | ▼ 2.23% |
Data source: Nexqual — real-time market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: June 10, 2026 at 00:52 UTC. This page is informational and not investment advice.