Precision BioSciences, Inc. (DTIL) Stock Price & Analysis

Precision BioSciences, Inc. (DTIL) closed at USD 9.68 on Monday, November 9, 2026, down 8.68% on the day. The US market is currently closed; this is not a live price.

The prior close was USD 10.6; the Nov 9, 2026 session ranged USD 9.62–10.8 on volume of 589,692 shares. Market capitalization is $369.49M, with a 52-week range of USD 3.53–11.29 (NCM). Source: Nexqual, retrieved November 10, 2026 at 04:58 UTC.

What changed for DTIL since Aug 31, 2025

The built-in knowledge of several widely used AI models ends around Aug 31, 2025. Everything below is newer, dated and sourced (as of Nov 9, 2026).

Also available as compact Markdown for AI agents: nexqual.com/DTIL.md

Key facts (DTIL)

Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (DTIL)

USDFY2021FY2022FY2023FY2024FY2025TTM
Revenue$116M$25.1M$48.7M$68.7M$34.3M$45.0M
Operating income-$39.4M-$62.3M-$43.7M-$26.2M-$52.1M-$36.2M
Net income-$30.6M-$112M-$61.3M$7.2M-$45.7M-$38.5M
EPS (diluted)-$15.60-$38.10-$15.96$1.04-$3.56—
Free cash flow-$15.9M-$49.1M-$86.1M-$58.7M-$65.9M-$51.8M
Operating margin-34.1%-248.3%-89.8%-38.1%-152.2%-80.3%
Net margin-26.5%-444.8%-125.8%10.4%-133.4%-85.6%
Revenue growth+375.7%-78.3%+94.1%+41.0%-50.1%—
Cash + short-term investments$144M$190M$117M$86.3M$116M—
Total debt$2.5M$22.2M————

Fiscal years end Dec. EPS is split-adjusted.

Valuation (price ÷ last four quarters, through Sep 30, 2026) (DTIL)

P/S 8.2x · P/B 7.1x · FCF yield -14.02% · Earnings yield -10.43%

P/E at fiscal year-ends: Dec 2024 3.7x.

Insider purchases (SEC Form 4, open-market, last ~7 months) (DTIL)

3 purchases, $30K. Private placements, offerings, dividend reinvestment and employee stock purchase plan buys are excluded.

Trade dateInsiderRoleSharesValueAvg priceInsider type
2026-09-28Frankel StanleyDirector1,000$6K6Too little history (no open-market trades in 2023 or 2024)
2026-09-25Brown MelindaDirector1,135$7K6.27Too little history (no open-market trades in 2023)
2026-09-25Germano Geno JDirector2,609$16K6.28Too little history (no open-market trades in 2023)

Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.

Analysts (DTIL)

Consensus Buy (mean 2.00 on a 1–5 scale), 5 analysts; mean target USD 29.4 (low 18, high 60).

Rating changes, last 120 days:

DateFirmActionRatingPrice target
2026-08-03HC Wainwright & Co.ReiteratedBuy$60

Total return (dividends reinvested) (DTIL)

1Y (from 2025-11-10)5Y (from 2021-11-08)
Total return+59.5%-96.7%
S&P 500 (SPY)+11.7%+72.2%
Per year+59.7%-49.5%
Volatility (annualized)72.9%74.9%
Max drawdown-41.2% (Nov 2025→Feb 2026)-98.7% (Nov 2021→Feb 2026)

Dividends (DTIL)

DTIL paid no cash dividend in the last five years.

Short interest (DTIL)

2,356,838 shares sold short, 8.66% of the float, as of Oct 15, 2026 (exchange short-interest report, published about twice a month). Prior report (Sep 15, 2026): 2,223,477 shares (+6.0%). Days to cover: 8.6 (short shares ÷ average daily volume).

DTIL earnings history and stock reaction

Results filedQuarterEPSConsensusSurpriseStock reaction
Nov 3, 2026Quarter ended Sep 30, 2026−$0.28−$0.89Beat +68.5%+16.8%
Aug 6, 2026Quarter ended Jun 30, 2026−$1.26−$0.69Miss −82.6%+0.3%
May 5, 2026Quarter ended Mar 31, 2026−$0.75−$0.81Beat +7.4%-1.4%
Mar 12, 2026Quarter ended Dec 31, 2025$1.01−$0.64Beat +$1.65+12.1%
Jan 13, 2026Quarter ended Dec 31, 2025$1.01−$0.64Beat +$1.65+1.7%
Nov 3, 2025————-18.0%
Aug 7, 2025————-8.9%
May 15, 2025————-4.8%

EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).

DTIL recent SEC filings (last 120 days)

FiledFormWhat it says
Nov 9, 20268-KOther material event
“As previously reported, on November 5, 2026, Precision BioSciences, Inc. (the "Company") entered into an underwriting agreement relating to the issuance and sale by the Company of 10,235,077 shares of its common stock, $0.000005 par value per share (the "Common Stock"), at a price of $7.75 per share and, in lieu of Common Stock to certain investors, pre-funded warrants to purchase up to 5,893,964 shares of its Common Stock at a price of $7.749995 per pre-funded warrant (the "Offering"). The Company expects net…”
Nov 6, 20268-KOther material event
“On November 5, 2026, Precision BioSciences, Inc. (the "Company") entered into an underwriting agreement (the "Underwriting Agreement") with TD Securities (USA) LLC and Guggenheim Securities, LLC, as representatives of the several underwriters named therein (the "Underwriters"), in connection with the offering (the "Offering"), issuance and sale by the Company of 10,235,077 shares of its common stock, $0.000005 par value per share (the "Common Stock"), at a price of $7.75 per share and, in lieu of Common Stock to…”
Nov 5, 20268-KRegulation FD disclosure; Other material event
“On November 5, 2026, the Company issued the HBV News Release announcing a late-breaking oral presentation at the American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2026. This presentation includes new and updated preliminary data from the ongoing Phase 1 ELIMINATE-B study of PBGENE-HBV, the first and only in vivo gene editing therapy designed to eliminate cccDNA, the root cause of chronic hepatitis B. The PBGENE Late Breaker Abstract for this presentation was published on November 5,…”
Nov 3, 2026Schedule 13G/AOctagon Capital Advisors LP, Octagon Investments Master Fund LP: 5.7% of shares, passive 5%+ holder (amended)
Nov 3, 20268-KQuarterly results
Nov 3, 202610-QQuarterly report · period ended Sep 30, 2026
Oct 27, 2026Schedule 13GBlackRock, Inc.: 5.0% of shares, passive 5%+ holder
Aug 24, 2026Schedule 13G/AWeinstein Benjamin: 4.0% of shares, passive 5%+ holder (amended)
Aug 24, 20268-KRegulation FD disclosure; Other material event
“On August 24, 2026, the Company issued a press release announcing the first patient has been dosed in its Phase 1/2 FUNCTION-DMD clinical trial evaluating PBGENE-DMD for the treatment of DMD.”
Aug 6, 202610-QQuarterly report · period ended Jun 30, 2026
Aug 6, 20268-KQuarterly results
Jul 29, 2026Schedule 13G/AEmpery Asset Management, LP, Ryan M. Lane: 5.0% of shares, passive 5%+ holder (amended)
Jul 27, 20268-KDirector or executive officer change, or pay arrangement; Regulation FD disclosure
Jul 20, 2026Schedule 13Gpassive 5%+ holder

Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.

DTIL suppliers, customers and competitors (named in its 10-K)

RelationshipCompanySentence in the filing
PartnerTG THERAPEUTICS, INC. (TGTX)“On January 7, 2024, we entered into a license agreement (the "TG License Agreement") with TG Cell Therapy, Inc. ("TG Subsidiary") and its parent company TG Therapeutics, Inc. ("TG Parent" and, together with TG Subsidiary, "TG Therapeutics"), pursuant to which we granted TG Subsidiary certain exclusive and non-exclusive license rights to develop, manufacture, and commercialize azercabtagene zapreleucel ("azer-cel")…”
PartnerImugene“Additionally on August 15, 2023, we and Imugene US entered into a license agreement (the "Imugene License Agreement"), pursuant to which we granted Imugene US certain exclusive and non-exclusive license rights to develop, manufacture, and commercialize oncological applications of our allogeneic CAR T therapy, azer-cel, and up to three additional research product candidates directed to targets that Imugene US may n…”
PartnerNovartis Pharma“In June 2022, we and Novartis Pharma AG ("Novartis") entered into a research and development collaboration and license agreement (the "Novartis Agreement") incorporating our custom ARCUS nucleases for potential treatments for certain diseases, including certain hemoglobinopathies such as sickle cell disease and beta thalassemia.”
PartnerCellectis S.A. (CLLS)“The license we received from Cellectis is subject to the rights of a preexisting license agreement that Cellectis entered into with a third party, and the license granted to us excludes any rights exclusively granted by Cellectis under such preexisting license, which preexisting license is limited to certain specific applications unrelated to the fields of human therapeutics, for so long as the rights under the pr…”
PartnerPrevail Therapeutics“The decrease of $34.4 million in revenue during the year ended December 31, 2025 was primarily the result of $52.7 million of revenue recognized in the prior period related to the conclusion of our agreement with Prevail Therapeutics, which represented all remaining deferred revenue under that agreement.”
PartnerCaribou Biosciences, Inc. (CRBU)“Additionally contributing to the decrease in revenue was $9.5 million of revenue recognized under the TG License Agreement and the Caribou Biosciences, Inc. license agreement in the prior year.”

Quoted from the company's 10-K filed Mar 12, 2026.

Companies that name DTIL in their SEC reports

Relationship to DTILCompanyFilingSentence
partnerTG THERAPEUTICS, INC. (TGTX)10-K Feb 27, 2026“Pursuant to our license agreement with Precision, we have an exclusive license to develop and commercialize Precision's azer-cel for the treatment of autoimmune and other non-oncology diseases and conditions as well as a non-exclusive license to manufacture azer-cel.”

DTIL company outlook (results filed Nov 3, 2026)

Quoted word-for-word from the SEC 8-K results press release.

DTIL analyst estimates and revisions

PeriodEPS estimate90 days agoChangeRevenue estimateAnalysts
Current quarter (ends Dec 2026)$-0.74$-0.78+$0.04$02
Next quarter (ends Mar 2027)$-0.39$-0.53+$0.14$01
Current fiscal year (ends Dec 2026)$-2.93$-3.38+$0.44$10.9M2
Next fiscal year (ends Dec 2027)$-1.76$-2.14+$0.38$9.3M3

DTIL options: expected move

ExpirationDaysATM implied volatilityExpected move
Nov 20, 202611179.3%±25.3%
Dec 18, 202639143.4%±16.8%
Jan 15, 202767149.4%±70.6%
Feb 19, 2027102103.0%±52.6%
May 21, 2027193101.2%±58.3%

30-day implied volatility 156.8% vs 97.1% realized over the last 30 trading days. Put/call ratio (volume) 0.79. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.

Key Statistics (as of November 10, 2026 at 04:58 UTC)

PriceUSD 9.68
Change▼ 8.68% (down)
Previous CloseUSD 10.6
OpenUSD 10.72
Day RangeUSD 9.62 – 10.8
52-Week RangeUSD 3.53 – 11.29
Volume589,692 shares
Market Cap$369.49M
ExchangeNCM

Technical Analysis (DTIL)

Nexqual's technical model rates DTIL "BUY" based on 5 bullish and 1 bearish signals across 127 daily candles, as of November 10, 2026 at 04:58 UTC.

Overall SignalBUY
RSI (14)70.26 (overbought)
vs SMA50Above (USD 6.93)
MACD0.73 (positive)

Analyst Ratings (DTIL)

Wall Street analysts rate DTIL "Buy" based on 5 analysts, with a mean price target of USD 29.4 (range USD 18–60), per Nexqual as of November 10, 2026 at 04:58 UTC.

Consensus RatingBuy
Analyst Count5
Mean TargetUSD 29.4
High TargetUSD 60
Low TargetUSD 18
Buy / Hold / Sell5 / 0 / 0

Earnings (DTIL)

Next Earnings Date2026-11-03
EPS EstimateUSD -0.74
Revenue Estimate$0

Recent Earnings History

QuarterActual vs Estimate
2026-09-30USD -0.28 vs est -0.89 ▲ beat
2026-06-30USD -1.26 vs est -0.69 ▼ miss
2026-03-31USD -0.75 vs est -0.81 ▲ beat
2025-12-31USD 1.01 vs est -0.64 ▲ beat

Source: Nexqual, November 10, 2026 at 04:58 UTC.

Financials & Fundamentals (DTIL)

Total Revenue$45.04M
Gross Margin+100.00%
Operating Margin-80.27%
Profit Margin-85.58%
ROE-115.28%
Debt / Equity0.54
Current Ratio10.47
Total Cash$81.85M
Total Debt$27.72M
Free Cash Flow (last four quarters to Sep 2026, SEC 10-Q / 10-K)-$51.80M (-115.0% of revenue)

Source: Nexqual, November 10, 2026 at 04:58 UTC.

Financial Health Score (DTIL)

Nexqual rates Precision BioSciences, Inc.'s overall financial health "Weak" across five dimensions, as of November 10, 2026 at 04:58 UTC.

GrowthMixed — No data
ProfitabilityWeak — Not yet profitable — scaling phase
Balance SheetStrong — $82M cash vs $28M debt, net cash position
Cash FlowWeak — FCF negative: -$52M (last 4 quarters to Sep 2026, SEC), burning cash
EfficiencyCritical — ROE -74%, ROA -32.0% (last 4 quarters, SEC)

Ownership (DTIL)

Insider Ownership+7.95%
Institutional Ownership+64.28%
Shares Outstanding38.17M
Float25.79M
Short % of Float+8.66%

Source: Nexqual, November 10, 2026 at 04:58 UTC.

Leadership (DTIL)

Precision BioSciences, Inc. is led by Michael Amoroso, President, CEO & Director, per Nexqual as of November 10, 2026 at 04:58 UTC.

President, CEO & DirectorMichael Amoroso
Chief Operating OfficerJohn Alexander Kelly R.Ph.
Chief Financial OfficerNaresh Tanna
Chief Scientific OfficerCassie Gorsuch

Major Backers & Investors (DTIL)

Notable institutional backers of Precision BioSciences, Inc. include Aberdeen Group plc, Bleichroeder LP, Octagon Capital Advisors LP, according to Nexqual as of November 10, 2026 at 04:58 UTC.

Active Investors

InvestorStake
Aberdeen Group plc7.98%
Bleichroeder LP7.22%
Octagon Capital Advisors LP4.83%
Boothbay Fund Management, LLC4.82%
abrdn World Healthcare Fund4.1%
abrdn Life Sciences Investors3.89%
Lynx1 Capital Management Lp3.4%
Driehaus Capital Management, LLC3.39%

Index Funds (Passive)

FundStake
BlackRock4.2%
Vanguard Group4%

Source: Nexqual, November 10, 2026 at 04:58 UTC.

From Precision BioSciences, Inc.'s Latest SEC 10-K Filing (filed 2026-03-12)

Key Strengths & Strategy (as disclosed to the SEC)

Partnerships

Legal & Regulatory Risks (Item 1A, quoted)

Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.

Peers & Related Stocks

SymbolNamePriceChange
IONSIonis Pharmaceuticals, Inc.USD 31▼ 21.36%
CGONCG Oncology, Inc.USD 74.74▼ 1.64%
ORKAOruka Therapeutics, Inc.USD 104.56▲ 1.65%
AXSMAxsome Therapeutics, Inc.USD 133.96▲ 1.2%
CAICaris Life Sciences, Inc.USD 25.57▲ 1.35%
CYTKCytokinetics, IncorporatedUSD 55.14▲ 2.7%

Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: November 10, 2026 at 04:58 UTC. This page is informational and not investment advice.

For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt