Precision BioSciences, Inc. (DTIL) Stock Price & Analysis
Precision BioSciences, Inc. (DTIL) closed at USD 9.68 on Monday, November 9, 2026, down 8.68% on the day. The US market is currently closed; this is not a live price.
The prior close was USD 10.6; the Nov 9, 2026 session ranged USD 9.62–10.8 on volume of 589,692 shares. Market capitalization is $369.49M, with a 52-week range of USD 3.53–11.29 (NCM). Source: Nexqual, retrieved November 10, 2026 at 04:58 UTC.
What changed for DTIL since Aug 31, 2025
The built-in knowledge of several widely used AI models ends around Aug 31, 2025. Everything below is newer, dated and sourced (as of Nov 9, 2026).
- Precision BioSciences, Inc. (DTIL) stock went from USD 4.9 (close of the week of Aug 25, 2025, split-adjusted) to USD 9.68, a +97.6% price change; the S&P 500 (SPY) moved +18.3% over the same period.
- DTIL revenue over the last four reported quarters (through Sep 30, 2026) was $45.0M, -34.4% vs $68.7M in fiscal year 2024 (ended Dec 31, 2024), the last full year filed before September 2025; net income $7.2M → -$38.5M (SEC 10-K / 10-Q).
- Analyst actions on DTIL in the last 120 days: 1 (0 upgrades or target raises, 0 downgrades or target cuts); most recent HC Wainwright & Co., Aug 3, 2026.
Also available as compact Markdown for AI agents: nexqual.com/DTIL.md
Key facts (DTIL)
- Last four reported quarters (through Sep 30, 2026): revenue $45.0M, net income -$38.5M (-85.6% margin), free cash flow -$51.8M (SEC filings).
- Insider open-market purchases, last ~7 months: 3 Form 4 filings, $30K; 0 by opportunistic insiders, 0 by routine insiders.
- Analysts: Buy (mean 2.00 on a 1–5 scale) (5 analysts), mean target USD 29.4 (range 18–60).
- Total return with dividends: 1Y +59.5% vs S&P 500 +11.7%; 5Y -96.7% vs S&P 500 +72.2%.
- Latest earnings report: 2026-11-03 (next date not yet announced).
- Dividend: DTIL paid no cash dividend in the last five years.
- Short interest: 8.66% of float (as of 2026-10-15), 8.6 days to cover.
Financials (SEC 10-K; TTM = last four 10-Q/10-K quarters) (DTIL)
| USD | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM |
|---|---|---|---|---|---|---|
| Revenue | $116M | $25.1M | $48.7M | $68.7M | $34.3M | $45.0M |
| Operating income | -$39.4M | -$62.3M | -$43.7M | -$26.2M | -$52.1M | -$36.2M |
| Net income | -$30.6M | -$112M | -$61.3M | $7.2M | -$45.7M | -$38.5M |
| EPS (diluted) | -$15.60 | -$38.10 | -$15.96 | $1.04 | -$3.56 | — |
| Free cash flow | -$15.9M | -$49.1M | -$86.1M | -$58.7M | -$65.9M | -$51.8M |
| Operating margin | -34.1% | -248.3% | -89.8% | -38.1% | -152.2% | -80.3% |
| Net margin | -26.5% | -444.8% | -125.8% | 10.4% | -133.4% | -85.6% |
| Revenue growth | +375.7% | -78.3% | +94.1% | +41.0% | -50.1% | — |
| Cash + short-term investments | $144M | $190M | $117M | $86.3M | $116M | — |
| Total debt | $2.5M | $22.2M | — | — | — | — |
Fiscal years end Dec. EPS is split-adjusted.
Valuation (price ÷ last four quarters, through Sep 30, 2026) (DTIL)
P/S 8.2x · P/B 7.1x · FCF yield -14.02% · Earnings yield -10.43%
P/E at fiscal year-ends: Dec 2024 3.7x.
Insider purchases (SEC Form 4, open-market, last ~7 months) (DTIL)
3 purchases, $30K. Private placements, offerings, dividend reinvestment and employee stock purchase plan buys are excluded.
| Trade date | Insider | Role | Shares | Value | Avg price | Insider type |
|---|---|---|---|---|---|---|
| 2026-09-28 | Frankel Stanley | Director | 1,000 | $6K | 6 | Too little history (no open-market trades in 2023 or 2024) |
| 2026-09-25 | Brown Melinda | Director | 1,135 | $7K | 6.27 | Too little history (no open-market trades in 2023) |
| 2026-09-25 | Germano Geno J | Director | 2,609 | $16K | 6.28 | Too little history (no open-market trades in 2023) |
Insider type follows Cohen, Malloy & Pomorski (Journal of Finance, 2012). An insider who traded the stock in the same calendar month in each of the past three years is a routine trader; one who traded in each of those years without such a pattern is an opportunistic trader. In their study, trades by opportunistic insiders predicted future returns and trades by routine insiders did not. Counts open-market purchases and sales only (SEC Form 4 codes P and S) by that insider in that company. Not investment advice.
Analysts (DTIL)
Consensus Buy (mean 2.00 on a 1–5 scale), 5 analysts; mean target USD 29.4 (low 18, high 60).
Rating changes, last 120 days:
| Date | Firm | Action | Rating | Price target |
|---|---|---|---|---|
| 2026-08-03 | HC Wainwright & Co. | Reiterated | Buy | $60 |
Total return (dividends reinvested) (DTIL)
| 1Y (from 2025-11-10) | 5Y (from 2021-11-08) | |
|---|---|---|
| Total return | +59.5% | -96.7% |
| S&P 500 (SPY) | +11.7% | +72.2% |
| Per year | +59.7% | -49.5% |
| Volatility (annualized) | 72.9% | 74.9% |
| Max drawdown | -41.2% (Nov 2025→Feb 2026) | -98.7% (Nov 2021→Feb 2026) |
Dividends (DTIL)
DTIL paid no cash dividend in the last five years.
Short interest (DTIL)
2,356,838 shares sold short, 8.66% of the float, as of Oct 15, 2026 (exchange short-interest report, published about twice a month). Prior report (Sep 15, 2026): 2,223,477 shares (+6.0%). Days to cover: 8.6 (short shares ÷ average daily volume).
DTIL earnings history and stock reaction
| Results filed | Quarter | EPS | Consensus | Surprise | Stock reaction |
|---|---|---|---|---|---|
| Nov 3, 2026 | Quarter ended Sep 30, 2026 | −$0.28 | −$0.89 | Beat +68.5% | +16.8% |
| Aug 6, 2026 | Quarter ended Jun 30, 2026 | −$1.26 | −$0.69 | Miss −82.6% | +0.3% |
| May 5, 2026 | Quarter ended Mar 31, 2026 | −$0.75 | −$0.81 | Beat +7.4% | -1.4% |
| Mar 12, 2026 | Quarter ended Dec 31, 2025 | $1.01 | −$0.64 | Beat +$1.65 | +12.1% |
| Jan 13, 2026 | Quarter ended Dec 31, 2025 | $1.01 | −$0.64 | Beat +$1.65 | +1.7% |
| Nov 3, 2025 | — | — | — | — | -18.0% |
| Aug 7, 2025 | — | — | — | — | -8.9% |
| May 15, 2025 | — | — | — | — | -4.8% |
EPS as reported against the analyst consensus before the release; surprise uses the cent-rounded figures shown (in dollars when EPS and consensus have opposite signs). Stock reaction = close before the results to close after (the first close following a release after the bell or before the open).
DTIL recent SEC filings (last 120 days)
| Filed | Form | What it says |
|---|---|---|
| Nov 9, 2026 | 8-K | Other material event “As previously reported, on November 5, 2026, Precision BioSciences, Inc. (the "Company") entered into an underwriting agreement relating to the issuance and sale by the Company of 10,235,077 shares of its common stock, $0.000005 par value per share (the "Common Stock"), at a price of $7.75 per share and, in lieu of Common Stock to certain investors, pre-funded warrants to purchase up to 5,893,964 shares of its Common Stock at a price of $7.749995 per pre-funded warrant (the "Offering"). The Company expects net…” |
| Nov 6, 2026 | 8-K | Other material event “On November 5, 2026, Precision BioSciences, Inc. (the "Company") entered into an underwriting agreement (the "Underwriting Agreement") with TD Securities (USA) LLC and Guggenheim Securities, LLC, as representatives of the several underwriters named therein (the "Underwriters"), in connection with the offering (the "Offering"), issuance and sale by the Company of 10,235,077 shares of its common stock, $0.000005 par value per share (the "Common Stock"), at a price of $7.75 per share and, in lieu of Common Stock to…” |
| Nov 5, 2026 | 8-K | Regulation FD disclosure; Other material event “On November 5, 2026, the Company issued the HBV News Release announcing a late-breaking oral presentation at the American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2026. This presentation includes new and updated preliminary data from the ongoing Phase 1 ELIMINATE-B study of PBGENE-HBV, the first and only in vivo gene editing therapy designed to eliminate cccDNA, the root cause of chronic hepatitis B. The PBGENE Late Breaker Abstract for this presentation was published on November 5,…” |
| Nov 3, 2026 | Schedule 13G/A | Octagon Capital Advisors LP, Octagon Investments Master Fund LP: 5.7% of shares, passive 5%+ holder (amended) |
| Nov 3, 2026 | 8-K | Quarterly results |
| Nov 3, 2026 | 10-Q | Quarterly report · period ended Sep 30, 2026 |
| Oct 27, 2026 | Schedule 13G | BlackRock, Inc.: 5.0% of shares, passive 5%+ holder |
| Aug 24, 2026 | Schedule 13G/A | Weinstein Benjamin: 4.0% of shares, passive 5%+ holder (amended) |
| Aug 24, 2026 | 8-K | Regulation FD disclosure; Other material event “On August 24, 2026, the Company issued a press release announcing the first patient has been dosed in its Phase 1/2 FUNCTION-DMD clinical trial evaluating PBGENE-DMD for the treatment of DMD.” |
| Aug 6, 2026 | 10-Q | Quarterly report · period ended Jun 30, 2026 |
| Aug 6, 2026 | 8-K | Quarterly results |
| Jul 29, 2026 | Schedule 13G/A | Empery Asset Management, LP, Ryan M. Lane: 5.0% of shares, passive 5%+ holder (amended) |
| Jul 27, 2026 | 8-K | Director or executive officer change, or pay arrangement; Regulation FD disclosure |
| Jul 20, 2026 | Schedule 13G | passive 5%+ holder |
Source: SEC EDGAR. Quotes are the opening words of each item as filed; each form links to the filing. Insider Form 4 filings are listed in the insider sections.
DTIL suppliers, customers and competitors (named in its 10-K)
| Relationship | Company | Sentence in the filing |
|---|---|---|
| Partner | TG THERAPEUTICS, INC. (TGTX) | “On January 7, 2024, we entered into a license agreement (the "TG License Agreement") with TG Cell Therapy, Inc. ("TG Subsidiary") and its parent company TG Therapeutics, Inc. ("TG Parent" and, together with TG Subsidiary, "TG Therapeutics"), pursuant to which we granted TG Subsidiary certain exclusive and non-exclusive license rights to develop, manufacture, and commercialize azercabtagene zapreleucel ("azer-cel")…” |
| Partner | Imugene | “Additionally on August 15, 2023, we and Imugene US entered into a license agreement (the "Imugene License Agreement"), pursuant to which we granted Imugene US certain exclusive and non-exclusive license rights to develop, manufacture, and commercialize oncological applications of our allogeneic CAR T therapy, azer-cel, and up to three additional research product candidates directed to targets that Imugene US may n…” |
| Partner | Novartis Pharma | “In June 2022, we and Novartis Pharma AG ("Novartis") entered into a research and development collaboration and license agreement (the "Novartis Agreement") incorporating our custom ARCUS nucleases for potential treatments for certain diseases, including certain hemoglobinopathies such as sickle cell disease and beta thalassemia.” |
| Partner | Cellectis S.A. (CLLS) | “The license we received from Cellectis is subject to the rights of a preexisting license agreement that Cellectis entered into with a third party, and the license granted to us excludes any rights exclusively granted by Cellectis under such preexisting license, which preexisting license is limited to certain specific applications unrelated to the fields of human therapeutics, for so long as the rights under the pr…” |
| Partner | Prevail Therapeutics | “The decrease of $34.4 million in revenue during the year ended December 31, 2025 was primarily the result of $52.7 million of revenue recognized in the prior period related to the conclusion of our agreement with Prevail Therapeutics, which represented all remaining deferred revenue under that agreement.” |
| Partner | Caribou Biosciences, Inc. (CRBU) | “Additionally contributing to the decrease in revenue was $9.5 million of revenue recognized under the TG License Agreement and the Caribou Biosciences, Inc. license agreement in the prior year.” |
Quoted from the company's 10-K filed Mar 12, 2026.
Companies that name DTIL in their SEC reports
| Relationship to DTIL | Company | Filing | Sentence |
|---|---|---|---|
| partner | TG THERAPEUTICS, INC. (TGTX) | 10-K Feb 27, 2026 | “Pursuant to our license agreement with Precision, we have an exclusive license to develop and commercialize Precision's azer-cel for the treatment of autoimmune and other non-oncology diseases and conditions as well as a non-exclusive license to manufacture azer-cel.” |
DTIL company outlook (results filed Nov 3, 2026)
- “Initial safety data are targeted for year-end 2026, with efficacy data at distinct timepoints expected to follow in H1 and H2 2027.”
- “The Company expects that existing cash and cash equivalents, continued fiscal and operating discipline, and availability of Precision's at-the-market facility will fund the Company's cash runway through 2028.”
- “Based on its expected cash runway, Precision projects it is sufficiently capitalized to achieve key PBGENE-HBV and PBGENE-DMD clinical data milestones through 2028.”
- “Revenues: As expected, no revenue was reported for the quarter ended September 30, 2026, compared to less than $0.1 million for the quarter ended September 30, 2025.”
Quoted word-for-word from the SEC 8-K results press release.
DTIL analyst estimates and revisions
| Period | EPS estimate | 90 days ago | Change | Revenue estimate | Analysts |
|---|---|---|---|---|---|
| Current quarter (ends Dec 2026) | $-0.74 | $-0.78 | +$0.04 | $0 | 2 |
| Next quarter (ends Mar 2027) | $-0.39 | $-0.53 | +$0.14 | $0 | 1 |
| Current fiscal year (ends Dec 2026) | $-2.93 | $-3.38 | +$0.44 | $10.9M | 2 |
| Next fiscal year (ends Dec 2027) | $-1.76 | $-2.14 | +$0.38 | $9.3M | 3 |
DTIL options: expected move
| Expiration | Days | ATM implied volatility | Expected move |
|---|---|---|---|
| Nov 20, 2026 | 11 | 179.3% | ±25.3% |
| Dec 18, 2026 | 39 | 143.4% | ±16.8% |
| Jan 15, 2027 | 67 | 149.4% | ±70.6% |
| Feb 19, 2027 | 102 | 103.0% | ±52.6% |
| May 21, 2027 | 193 | 101.2% | ±58.3% |
30-day implied volatility 156.8% vs 97.1% realized over the last 30 trading days. Put/call ratio (volume) 0.79. Cboe delayed quotes (15 min). Expected move = at-the-money straddle.
Key Statistics (as of November 10, 2026 at 04:58 UTC)
| Price | USD 9.68 |
|---|---|
| Change | ▼ 8.68% (down) |
| Previous Close | USD 10.6 |
| Open | USD 10.72 |
| Day Range | USD 9.62 – 10.8 |
| 52-Week Range | USD 3.53 – 11.29 |
| Volume | 589,692 shares |
| Market Cap | $369.49M |
| Exchange | NCM |
Technical Analysis (DTIL)
Nexqual's technical model rates DTIL "BUY" based on 5 bullish and 1 bearish signals across 127 daily candles, as of November 10, 2026 at 04:58 UTC.
| Overall Signal | BUY |
|---|---|
| RSI (14) | 70.26 (overbought) |
| vs SMA50 | Above (USD 6.93) |
| MACD | 0.73 (positive) |
Analyst Ratings (DTIL)
Wall Street analysts rate DTIL "Buy" based on 5 analysts, with a mean price target of USD 29.4 (range USD 18–60), per Nexqual as of November 10, 2026 at 04:58 UTC.
| Consensus Rating | Buy |
|---|---|
| Analyst Count | 5 |
| Mean Target | USD 29.4 |
| High Target | USD 60 |
| Low Target | USD 18 |
| Buy / Hold / Sell | 5 / 0 / 0 |
Earnings (DTIL)
| Next Earnings Date | 2026-11-03 |
|---|---|
| EPS Estimate | USD -0.74 |
| Revenue Estimate | $0 |
Recent Earnings History
| Quarter | Actual vs Estimate |
|---|---|
| 2026-09-30 | USD -0.28 vs est -0.89 ▲ beat |
| 2026-06-30 | USD -1.26 vs est -0.69 ▼ miss |
| 2026-03-31 | USD -0.75 vs est -0.81 ▲ beat |
| 2025-12-31 | USD 1.01 vs est -0.64 ▲ beat |
Source: Nexqual, November 10, 2026 at 04:58 UTC.
Financials & Fundamentals (DTIL)
| Total Revenue | $45.04M |
|---|---|
| Gross Margin | +100.00% |
| Operating Margin | -80.27% |
| Profit Margin | -85.58% |
| ROE | -115.28% |
| Debt / Equity | 0.54 |
| Current Ratio | 10.47 |
| Total Cash | $81.85M |
| Total Debt | $27.72M |
| Free Cash Flow (last four quarters to Sep 2026, SEC 10-Q / 10-K) | -$51.80M (-115.0% of revenue) |
Source: Nexqual, November 10, 2026 at 04:58 UTC.
Financial Health Score (DTIL)
Nexqual rates Precision BioSciences, Inc.'s overall financial health "Weak" across five dimensions, as of November 10, 2026 at 04:58 UTC.
| Growth | Mixed — No data |
|---|---|
| Profitability | Weak — Not yet profitable — scaling phase |
| Balance Sheet | Strong — $82M cash vs $28M debt, net cash position |
| Cash Flow | Weak — FCF negative: -$52M (last 4 quarters to Sep 2026, SEC), burning cash |
| Efficiency | Critical — ROE -74%, ROA -32.0% (last 4 quarters, SEC) |
Ownership (DTIL)
| Insider Ownership | +7.95% |
|---|---|
| Institutional Ownership | +64.28% |
| Shares Outstanding | 38.17M |
| Float | 25.79M |
| Short % of Float | +8.66% |
Source: Nexqual, November 10, 2026 at 04:58 UTC.
Leadership (DTIL)
Precision BioSciences, Inc. is led by Michael Amoroso, President, CEO & Director, per Nexqual as of November 10, 2026 at 04:58 UTC.
| President, CEO & Director | Michael Amoroso |
|---|---|
| Chief Operating Officer | John Alexander Kelly R.Ph. |
| Chief Financial Officer | Naresh Tanna |
| Chief Scientific Officer | Cassie Gorsuch |
Major Backers & Investors (DTIL)
Notable institutional backers of Precision BioSciences, Inc. include Aberdeen Group plc, Bleichroeder LP, Octagon Capital Advisors LP, according to Nexqual as of November 10, 2026 at 04:58 UTC.
Active Investors
| Investor | Stake |
|---|---|
| Aberdeen Group plc | 7.98% |
| Bleichroeder LP | 7.22% |
| Octagon Capital Advisors LP | 4.83% |
| Boothbay Fund Management, LLC | 4.82% |
| abrdn World Healthcare Fund | 4.1% |
| abrdn Life Sciences Investors | 3.89% |
| Lynx1 Capital Management Lp | 3.4% |
| Driehaus Capital Management, LLC | 3.39% |
Index Funds (Passive)
| Fund | Stake |
|---|---|
| BlackRock | 4.2% |
| Vanguard Group | 4% |
Source: Nexqual, November 10, 2026 at 04:58 UTC.
From Precision BioSciences, Inc.'s Latest SEC 10-K Filing (filed 2026-03-12)
Key Strengths & Strategy (as disclosed to the SEC)
- Recently, iECURE reached alignment with the FDA on the primary and key secondary efficacy endpoints, comparators and study size for the ongoing OTC-HOPE study which could support a Biologics License Application.
- We seek to protect our proprietary technology and processes, in part, by monitoring confidential disclosures and through confidentiality agreements and invention assignment agreements with our employees, consultants, scientific advisors, contractors and others who may have access to proprietary information, under which they are bound to assign to us inventions made during the term of their employment or term of service.
- We also rely on trademarks, trade secrets, know-how, continuing technological innovation and confidential information, and the pursuit of licensing opportunities, to develop and maintain our proprietary position and protect aspects of our business that are not amenable to, or that we do not consider appropriate for, patent protection.
- We cannot be sure that patents will be granted with respect to any patent applications we have licensed or filed or may license or file in the future, and we cannot be sure that any patents we have licensed or which have been granted to us, or patents that may be licensed or granted to us in the future, will not be challenged, invalidated or circumvented or that such patents will be commercially useful in protecting our technology.
Partnerships
- In partnership with iECURE, Inc. ("iECURE"), an ARCUS-mediated targeted gene insertion approach, ECUR-506, is being evaluated as a potential curative treatment option for neonatal onset ornithine transcarbamylase ("OTC") deficiency.
- In connection with the iECURE DLA, we and iECURE entered into an equity issuance agreement (the "iECURE Equity Agreement"), pursuant to which iECURE issued us common stock in iECURE as additional consideration for the license to use our PCSK9-directed ARCUS nuclease.
Legal & Regulatory Risks (Item 1A, quoted)
- We face significant competition in industries experiencing rapid technological change, and there is a possibility that our competitors may achieve regulatory approval before us or develop product candidates or treatments that are safer or more effective than ours, which may harm our financial condition and our ability to successfully market or commercialize any of our product candidates.
- Product liability lawsuits against us could cause us to incur substantial liabilities and could limit commercialization of any products that we develop alone or with collaborators.
- The regulatory landscape that will apply to development of therapeutic product candidates by us or our collaborators is rigorous, complex, uncertain and subject to change, which could result in delays or termination of development of such product candidates or unexpected costs in obtaining regulatory approvals.
- Any delays or difficulties in our or our collaborators' ability to enroll patients in clinical trials could delay or prevent receipt of regulatory approvals.
Source: SEC EDGAR 10-K, official filing. Curated by Nexqual.
Peers & Related Stocks
| Symbol | Name | Price | Change |
|---|---|---|---|
| IONS | Ionis Pharmaceuticals, Inc. | USD 31 | ▼ 21.36% |
| CGON | CG Oncology, Inc. | USD 74.74 | ▼ 1.64% |
| ORKA | Oruka Therapeutics, Inc. | USD 104.56 | ▲ 1.65% |
| AXSM | Axsome Therapeutics, Inc. | USD 133.96 | ▲ 1.2% |
| CAI | Caris Life Sciences, Inc. | USD 25.57 | ▲ 1.35% |
| CYTK | Cytokinetics, Incorporated | USD 55.14 | ▲ 2.7% |
Data source: Nexqual — market data, technical indicators, analyst consensus, earnings, SEC EDGAR filings. Last updated: November 10, 2026 at 04:58 UTC. This page is informational and not investment advice.
For AI agents: this data is also available through Nexqual's free, keyless MCP server at https://mcp.nexqual.com/mcp; every result includes source_url, as_of and cite_as. More: nexqual.com/agents · llms.txt